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    South Carolina Office Properties & Spaces for Lease

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    Columbia, SC Greenville, SC Charleston, SC
    Showing 24 of 1,257 results
    West Greenville Studio Space Available
    $850 /Mo
    4,667 SF

    West Greenville Studio Space Available

    Creative studios and workspaces in dynamic West Greenville neighborhood.

    31 Burdette St, Greenville, SC 29611
    View details
    COMMERCIAL - Aiken, SC
    $2,950 /Mo
    4,000 SF

    COMMERCIAL - Aiken, SC

    Warehouses · 4,000 SF

    1908 Richland Avenue E, Aiken, SC 29801
    View details
    Wappoo Creek Office Space Available
    $20 SF/Yr
    2,944 SF

    Wappoo Creek Office Space Available

    Office space for lease in a convenient Charleston location.

    125 Wappoo Creek Dr, Charleston, SC 29412
    View details
    Class A Office & Lifestyle Center
    $43 SF/Yr
    13,200 SF

    Class A Office & Lifestyle Center

    Two-story office building in a park-like setting with walking trails.

    255 New Riverside Village Way, Bluffton, SC 29910
    View details
    Highway 170 Retail/Office/Medical Space
    $36 SF/Yr
    3,970 SF

    Highway 170 Retail/Office/Medical Space

    Retail, office, or medical space for sale on Highway 170.

    Bluffton, SC 29909
    View details
    Office Space in Marion, SC
    $1,000 /Mo
    2,000 SF

    Office Space in Marion, SC

    Office space featuring a reception area, offices, and conference room.

    1450 E Northside Avenue, Marion, SC 29571
    View details
    Class A Office Space Available
    $25 SF/Yr
    9,660 SF

    Class A Office Space Available

    Class A office building with monument signage on Palmetto Bay Road.

    19 Bow Circle Ste A, Hilton Head Island, SC 29928
    View details
    Daniel Island Office Space Available
    $32 SF/Yr
    3,975 SF

    Daniel Island Office Space Available

    Second-floor office suite in Daniel Island's Town Center.

    115 Riverlanding Dr, Charleston, SC
    View details
    Medical Office Space For Lease
    $20 SF/Yr
    7,659 SF

    Medical Office Space For Lease

    Medical office space in prime healthcare corridor location.

    161 Medical Circle, West Columbia, SC 29169
    View details
    James Island Office Space Available
    $20 SF/Yr
    2,200 SF

    James Island Office Space Available

    Office space for lease in a convenient Charleston location.

    125 Wappoo Creek Dr, Charleston, SC 29412
    View details
    Class A Medical Office Building
    $28 SF/Yr
    14,084 SF

    Class A Medical Office Building

    Renovated medical/office building with ample parking in Mt. Pleasant.

    1200 Innovation Way, Mount Pleasant, SC 29466
    View details
    Flex Space Near Interstate I-26
    $15 SF/Yr
    2,520 SF

    Flex Space Near Interstate I-26

    Professional flex and light manufacturing space with easy interstate access.

    104 Corporate Boulevard, West Columbia, SC 29169
    View details
    Retail Space in Whitehall Commons
    $13 SF/Yr
    1,200 SF

    Retail Space in Whitehall Commons

    Retail or office space available in a high-traffic area.

    1486 Pearman Dairy Road, Anderson, SC 29625
    View details
    Class A Office Space Available
    $34 SF/Yr
    8,452 SF

    Class A Office Space Available

    Four-story, 102,024 SF Class A office building for lease.

    4401 Leeds Avenue, North Charleston, SC 29405
    View details
    Functional Space in Sea Island
    $12 SF/Yr
    2,710 SF

    Functional Space in Sea Island

    2,710 SF warehouse and office space for lease.

    3609 River Road, Johns Island, SC 29455
    View details
    Class A Office Space Available
    $24 SF/Yr
    3,607 SF

    Class A Office Space Available

    Office space available November 2025 in Myrtle Beach, SC.

    2050 Corporate Center Dr., Myrtle Beach, SC 29577
    View details
    Prime Office Space on Devine
    $23 SF/Yr
    12,200 SF

    Prime Office Space on Devine

    Office space for lease in the Devine Street District.

    2422 Devine Street, Columbia, SC 29205
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    Myrtle Beach Office Space Available
    $3,250 /Mo
    2,400 SF

    Myrtle Beach Office Space Available

    Office space for rent in Myrtle Beach, South Carolina.

    1455 Commerce Pl., Myrtle Beach, SC 29577
    View details
    Highway 170 Retail/Office/Medical Space
    $36 SF/Yr

    Highway 170 Retail/Office/Medical Space

    Retail, office, or medical space for lease on Highway 170.

    48 Terrace Drive, Okatie, SC 29909
    View details
    Warehouse with Secured Yard
    $12 SF/Yr
    5,000 SF

    Warehouse with Secured Yard

    5,000 SF warehouse with office and secured yard.

    125 North Shorecrest Drive, Columbia, SC 29209
    View details
    Flex Space Near I-26
    $10 SF/Yr
    3,000 SF

    Flex Space Near I-26

    3,000 SF flex space with office, warehouse, and laydown yard.

    7120 Broad River Road, Irmo, SC 29063
    View details
    Class A Office Space
    $43 SF/Yr
    9,675 SF

    Class A Office Space

    Multi-tenant office building in Charleston's Historic District.

    100 Calhoun Street, Charleston, SC 29401
    View details
    Forestbrook Road Office Space
    $16 SF/Yr
    1,400 SF

    Forestbrook Road Office Space

    1,400 SF office space in Myrtle Beach for lease.

    2523 Forestbrook Road, Unit D, Myrtle Beach, SC 29579
    View details
    Landmark Center Retail/Office Space
    $2,000 /Mo
    1,250 SF

    Landmark Center Retail/Office Space

    Retail or office space in Bluffton's Landmark Center.

    49 Pennington Drive, Unit 2F, Bluffton, SC 29910
    View details
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