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    South Carolina Commercial Real Estate for Lease

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    Greenville, SC Columbia, SC Charleston, SC
    Showing 24 of 3,121 listings
    High-Traffic Retail/Office Space Available
    $16 SF/Yr
    10,361 SF
    High-Traffic Retail/Office Space Available

    Highly visible commercial space on a primary Myrtle Beach corridor.

    2903 North Kings Highway, Myrtle Beach, SC 29577

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    Downtown Conway Professional Office Space
    $18 SF/Yr
    7,000 SF
    Downtown Conway Professional Office Space

    Professional office space in Downtown Conway, available in 2025.

    1312 2nd Avenue, Conway, SC 29577

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    Georgetown Historic District Retail Space
    $3,800/Mo
    1,200 SF
    Georgetown Historic District Retail Space

    Move-in ready retail space in Georgetown's Historic District.

    718 Front St, Georgetown, SC 29440

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    Charleston Historic District Office Space
    $22 SF/Yr
    4,204 SF
    Charleston Historic District Office Space

    Renovated office suites with harbor views in historic Charleston.

    2 Cumberland St, Charleston, SC 29401

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    Premier Medical Office Space Available
    $20 SF/Yr
    7,039 SF
    Premier Medical Office Space Available

    Class A medical office space in Spartanburg's prime location.

    1650 Skylyn Drive, Spartanburg, SC 29307

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    Freestanding Retail Building For Lease
    $14 SF/Yr
    5,000 SF
    Freestanding Retail Building For Lease

    Freestanding retail building in high-traffic area near Dutch Square Mall.

    422 Bush River Road, Columbia, SC 29210

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    Georgetown Flex Office/Warehouse Space
    $0.73 SF/Yr
    6,000 SF
    Georgetown Flex Office/Warehouse Space

    6000 sqft flex office/warehouse space in downtown Georgetown.

    1434 Hawkins Street, Georgetown, SC 29440

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    Retail Space in Summerville
    $30 SF/Yr
    3,780 SF
    Retail Space in Summerville

    Retail space for lease in a prime Summerville location.

    710 Bacons Bridge Rd, Summerville, SC 29485

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    Mount Pleasant Retail Space Available
    $24 SF/Yr
    5,250 SF
    Mount Pleasant Retail Space Available

    Retail space in prime Mount Pleasant location, available June 1, 2026.

    543 Long Point Road, Mount Pleasant, SC 29464

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    Trade Shops/Warehouse Space Available
    $800/Mo
    1,250 SF
    Trade Shops/Warehouse Space Available

    Move-in ready units ideal for automotive, trade, and manufacturing.

    2352 Highway 9 East, Longs, SC 29568

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    Ashley Riverview Center Office Space
    $27 SF/Yr
    10,092 SF
    Ashley Riverview Center Office Space

    Multi-tenant office building with Ashley River views and easy access.

    4401 Belle Oaks Dr, North Charleston, SC 29405

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    Prime Retail/Office Space Available
    $12 SF/Yr
    11,970 SF
    Prime Retail/Office Space Available

    Two-story retail/office space in high-traffic Myrtle Beach location.

    6613 N Kings Hwy, Myrtle Beach, SC 29572

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    James Island Office Space Available
    $20 SF/Yr
    2,200 SF
    James Island Office Space Available

    Office space for lease in a convenient Charleston location.

    125 Wappoo Creek Dr, Charleston, SC 29412

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    Retail Space in Commercial Corridor
    $38 SF/Yr
    6,200 SF
    Retail Space in Commercial Corridor

    Highly visible retail space with flexible sizes in Manning, SC.

    2660 Paxville Hwy, Manning, SC 29102

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    Office/Warehouse Space in North Industrial
    $5,833/Mo
    5,000 SF
    Office/Warehouse Space in North Industrial

    5,000 SF office/warehouse space for lease in Myrtle Beach.

    1460 Dividend Loop Unit C, Myrtle Beach, SC 29577

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    Industrial Opportunity in Myrtle Beach
    $7,200/Mo
    2,242 SF
    Industrial Opportunity in Myrtle Beach

    Functional industrial space ideal for distribution, manufacturing, or trade services.

    3201 Mr Joe White Ave, Myrtle Beach, SC 29577

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    Oceanfront Retail Space Available
    $24 SF/Yr
    2,200 SF
    Oceanfront Retail Space Available

    Prime retail space near campgrounds, available Q1 2026.

    5905 S Kings Hwy, Myrtle Beach, SC 29575

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    Retail Space in Whitehall Commons
    $13 SF/Yr
    1,200 SF
    Retail Space in Whitehall Commons

    Retail or office space available in a high-traffic area.

    1486 Pearman Dairy Road, Anderson, SC 29625

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    Freestanding Building with Drive-Thru
    $35 SF/Yr
    3,400 SF
    Freestanding Building with Drive-Thru

    Freestanding building with drive-thru, convenient access, and high visibility.

    700 N Main St, Summerville, SC 29483

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    Restaurant Space in Drayton Mills
    $29 SF/Yr
    6,979 SF
    Restaurant Space in Drayton Mills

    Second-generation restaurant space in a historic mixed-use development.

    1802 Drayton Road Suite I, Spartanburg, SC 29307

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    Reimagined Class-A Office Space
    $25 SF/Yr
    7,521 SF
    Reimagined Class-A Office Space

    Newly renovated office space in prime downtown location.

    1710 Gervais St., Columbia, SC 29201

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    Office and Flex Warehouse Space
    $1,950/Mo
    2,400 SF
    Office and Flex Warehouse Space

    Office and flex warehouse spaces available for lease.

    354 Tiller Dr, Pawleys Island, SC 29585

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    Myrtle Beach Retail/Office Unit
    $13 SF/Yr
    5,000 SF
    Myrtle Beach Retail/Office Unit

    Retail/office unit in Myrtle Beach's Arts & Innovation District.

    515 9th Avenue North, Myrtle Beach, SC 29577

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    Turnkey Restaurant Space in Iva
    $2,150/Mo
    2,700 SF
    Turnkey Restaurant Space in Iva

    Move-in ready restaurant space with high visibility and convenient access.

    624 East Front Street, Iva, SC 29655

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