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    South Carolina Commercial Real Estate for Lease

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    Greenville, SC Columbia, SC Myrtle Beach, SC Charleston, SC North Charleston, SC Spartanburg, SC Rock Hill, SC Conway, SC
    3,007 properties
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    Walmart-Anchored Retail Center Space
    Walmart-Anchored Retail Center Space

    651 Hwy 28 Bypass, Anderson, SC 29625

    $3,200/Mo
    Multi-tenant  5,680 sqft  223,211 GLA
    27,300 VPD  Walmart, Dollar Tree co-tenants

    Several retail suites are available in a center with multiple established national and service tenants.

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    Professional Office Units
    Professional Office Units

    4559 Oleander Dr., Myrtle Beach, SC 29577

    $5,007/Mo
    8–14 people  2,225 sqft  0.85 acres

    Brand-new office suites feature private entrances, signage opportunities, and adaptable layouts.

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    Office Unit with Private Offices
    Office Unit with Private Offices

    1003 Prince St., Georgetown, SC 29440

    $2,180/Mo
    4–7 people  1,189 sqft  0.1 acres

    Commercially zoned suite with a reception area and flexible consultation room layout.

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    End Cap Flex Space
    End Cap Flex Space

    4512 Dick Pond Rd. Dependable Service Bldg @, Myrtle Beach, SC 29588

    $7,207/Mo
    3,459 sqft  Built 2026

    New-construction flex suite with open planning, two restrooms, and a side-access overhead door.

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    Endcap Retail or Office Space
    Endcap Retail or Office Space

    1638 North Main Street, Anderson, SC 29621

    $11 SF/Yr
    2,696 sqft

    Endcap space with strong daily traffic, signalized access, and 47 parking spaces for retail or office users.

    47 parking spaces
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    Storefront Property on Highway 501
    Storefront Property on Highway 501

    942 Highway 501, Myrtle Beach, SC 29577

    $1,500/Mo
    1,800 sqft  Built 1968

    The 1,800-square-foot property sits on a wooded lot with public water service.

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    Freestanding Office Building
    Freestanding Office Building

    607 19th Ave. N, Myrtle Beach, SC 29577

    $4,750/Mo
    8–14 people  2,230 sqft
    6 private offices  1 meeting rooms  Highway access + Road access

    Six-office configuration with a conference room, reception area, kitchen breakroom, and two bathrooms.

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    Private Office Unit
    Private Office Unit

    139 Waterloo Street SW, Aiken, SC 29801

    Triple net (NNN)
    $500/Mo
    1 person  101 sqft  Built 1956

    Professional workspace within a multi-office property with shared common areas and off-street parking.

    30 parking spaces
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    Flex Building with Outdoor Storage
    Flex Building with Outdoor Storage

    1629 Union Street, Spartanburg, SC 29306

    $10.95 SF/Yr
    5,000 sqft  6 drive-in  Built 2026  Clear span
    Highway access

    New construction pairs a clear-span warehouse with office space and grade-level loading.

    Outdoor storage
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    Warehouse with Fenced Yard
    Warehouse with Fenced Yard

    572 Longs Pond Road, Lexington, SC 29073

    $4,250/Mo
    4,800 sqft

    Warehouse space includes renovated office area, a mezzanine, two grade-level doors, and an enclosed outdoor storage area.

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    Office Units with Conference Room Access
    Office Units with Conference Room Access

    203 West Main Street E4 & E5, Lexington, SC 29072

    $994/Mo
    1–2 people  400 sqft  Built 2010

    Shared building amenities include a kitchenette, waiting area, restrooms, and internet availability.

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    Retail Suite with Office
    Retail Suite with Office

    2126 Hwy 9 E, Unit F-5, Longs, SC 29568

    $2,000/Mo
    1,188 sqft
    Highway access

    An open-plan commercial space includes a private office, restroom, and rear storage area.

    Private Office  Restroom  Rear Storage Area  Shared Parking Lot
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    Office Suite with Conference Room
    Office Suite with Conference Room

    121 Professional Ln., Pawleys Island, SC 29585

    $2,125/Mo
    6–10 people  1,500 sqft  0.46 acres

    Professional office space includes a kitchen, restroom, parking, and convenient access to US-17.

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    Retail/Showroom Space
    Retail/Showroom Space

    260 John C Calhoun Dr, Orangeburg, SC 29115

    Modified gross
    $8 SF/Yr
    7,350 sqft

    B-1-zoned space along Hwy 301 offers a broad footprint for retail, showroom, and service-commercial uses.

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    Private-Entry Office Unit
    Private-Entry Office Unit

    139 Waterloo Street SW, Aiken, SC 29801

    Triple net (NNN)
    $650/Mo
    1 person  134 sqft  Built 1956

    Professional office setting with shared common areas and private off-street parking for employees and clients.

    30 parking spaces
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    Office Units with Monument Signage
    Office Units with Monument Signage

    714 South Lake Drive, Lexington, SC 29072

    $21 SF/Yr
    31–51 people  7,785 sqft

    The property offers a stated parking ratio of 6.67 spaces per 1,000 RSF.

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    Class A Professional Office Suite
    Class A Professional Office Suite

    4559 Oleander Dr. Suite 3, Myrtle Beach, SC 29577

    $5,007/Mo
    8–14 people  2,225 sqft  Built 2026

    Newly built office suite with a private entrance, signage opportunities, and on-site parking.

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    Flex Space with Laydown Yard
    Flex Space with Laydown Yard

    858 Kingswood Dr., Conway, SC 29526

    $3,198/Mo
    2,414 sqft
    Highway access

    HC-zoned space pairs office and warehouse functions with an outdoor storage area.

    Outdoor storage
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    New Professional Office Suite
    New Professional Office Suite

    4559 Oleander Dr. Suite 2, Myrtle Beach, SC 29577

    $5,007/Mo
    8–14 people  2,225 sqft  Built 2026

    Brand-new office space offers a private entrance, signage opportunities, and flexible layout options for professional users.

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    Retail Strip Center Space
    Retail Strip Center Space

    4998 Carolina Forest Blvd. Unit 2, Myrtle Beach, SC 29579

    $6,891/Mo
    2,432 sqft  Built 2026

    Pre-leasing retail space near major retailers in a dense residential and commercial corridor.

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    In-Line Retail Suite
    In-Line Retail Suite

    10729 Ocean Highway #Unit C, Pawleys Island, SC 29585

    $2,888/Mo
    Multi-tenant  1,083 sqft
    Bistro 217, Rustic Table co-tenants  Corner location

    GC-zoned commercial space sits at the Ocean Highway and Professional Lane corner near established dining and shopping businesses.

    Signage opportunities
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    Retail Endcap Suite
    Retail Endcap Suite

    2402 Whiskey Rd, Aiken, SC 29803

    Gross
    $3,950/Mo
    Multi-tenant  2,160 sqft  Endcap
    41,000 VPD

    Endcap retail space in Gabriel Center with access to shared parking and neighboring national retailers.

    Cross access
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    Coffee Shop with Covered Patio
    Coffee Shop with Covered Patio

    1301 Gervais St, Columbia, SC 29201

    $1,857/Mo
    1,857 sqft

    Indoor seating pairs with a covered outdoor area for customer service.

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    Restored Office Space in Historic Building
    Restored Office Space in Historic Building

    4 / 8 North Atlantic Wharf, Charleston, SC 29401

    French Quarter
    $30 SF/Yr
    10–17 people  1 space  2,566 sqft
    11 private offices  1 meeting rooms

    Restored office unit with open workspace, private offices, and conference room in a historic Charleston building.

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