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Horry County, SC Office Spaces for Lease

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82 properties
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Flexible Offices and Coworking at SC, North Myrtle Beach- 2nd Ave. Contact us today to book a tour!
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New Mixed-Use Space
Updated: Sep 8
New Mixed-Use Space

5100 Highway 17 Bypass, Murrells Inlet, SC 29576

$3,125/Mo
2,500 sqft 1.90 AC lot
2,500 SF available within a 12,000 SF mixed‑use building
Can be configured as two 1,250 SF suites or one 2,500 SF space
Direct exposure on Highway 17 Bypass with approximately 36,700 vehicles per day
1.9‑acre site with ample parking
Projected completion March 2027
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Office Suite with Private Restroom
Updated: Sep 25
Office Suite with Private Restroom

618 Chestnut Rd., Myrtle Beach, SC 29572

$1,550/Mo
555 sqft 0.44 AC lot
555‑square‑foot second‑floor office suite
Reception area, three offices, and a private restroom
10‑foot ceilings and windows providing natural light
Accessible by two staircases
Near Highway 17, with access to Highways 31 and 22
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Medical Office Suite in Professional Park
Medical Office Suite in Professional Park

710 21st Ave. N, Myrtle Beach, SC 29577

$1,166/Mo
560 sqft 0.16 AC lot

The space is part of a multi-building office park with medical and professional units.

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Multi-Suite Office Property
Multi-Suite Office Property

1013 Surf Pine Dr, Surfside Beach, SC 29575

$4,500/Mo
3,419 sqft 0.60 AC lot

Two-level commercial layout includes private offices, conference rooms, storage, and a fenced outdoor area.

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Renovated Medical Office Suite
Renovated Medical Office Suite

4310 Highway 17 Business, Murrells Inlet, SC 29576

$8,000/Mo
3,557 sqft 3.00 AC lot

Recently renovated Class A space with shared patient amenities, dedicated elevators, and services included in the lease package.

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Medical Office Suite
Medical Office Suite

710 21st Ave. N, Myrtle Beach, SC 29577

$2,410/Mo
1,157 sqft 0.16 AC lot

A medical and professional office unit is available within a multi-building office park.

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Second-Floor Office Unit
Second-Floor Office Unit

870 Inlet Square Dr., Murrells Inlet, SC 29576

$1,450/Mo
1,246 sqft 0.59 AC lot

HC-zoned office space positioned near major commercial and recreational destinations in Murrells Inlet.

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New Medical Office Suites
New Medical Office Suites

5100 Highway 17, Murrells Inlet, SC 29576

$3,125/Mo
2,500 sqft

New construction with adaptable suite layouts, on-site parking, and direct exposure along a heavily traveled commercial corridor.

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First-Floor Professional Office Suite
First-Floor Professional Office Suite

3876 Renee Dr., Myrtle Beach, SC 29579

$3,920/Mo
2,352 sqft 0.56 AC lot

Eight private offices, two conference rooms, and a reception area create a defined workspace layout.

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Professional Office Suite
Professional Office Suite

4728 Jenn Dr., Myrtle Beach, SC 29577

$3,100/Mo
1,500 sqft 1.90 AC lot

Configured with private offices, a conference room, reception area, and shared restroom access.

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Office Suite with Private Offices
Office Suite with Private Offices

2001 S Ocean Blvd, Myrtle Beach, SC 29577

$2,500/Mo
2,200 sqft

The MU-H-zoned space has a reception area, coffee bar, private offices, and potential for other uses subject to approvals.

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Multi-Suite Office Property
Multi-Suite Office Property

1013 Surf Pine Dr., Surfside Beach, SC 29575

$4,500/Mo
3,419 sqft 0.60 AC lot

Flexible office configuration with private rooms, meeting areas, kitchen facilities, storage, and a secured outdoor yard.

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Office Suite with Private Offices
Office Suite with Private Offices

2001 Ocean Blvd. S, Myrtle Beach, SC 29577

$2,500/Mo
2,200 sqft

A former professional-office layout includes reception, private rooms, a work area, and two restrooms.

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First-Floor Professional Office Suite
First-Floor Professional Office Suite

3876 Renee Dr. Unit A, Myrtle Beach, SC 29579

$3,920/Mo
2,352 sqft

The layout includes private offices, meeting rooms, a reception area, a waiting room, and a kitchenette.

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Office Unit with Balcony
Office Unit with Balcony

4603 Oleander Dr., Myrtle Beach, SC 29577

$1,750/Mo
800 sqft 0.16 AC lot

The suite combines private offices with reception, kitchen, restroom, and paved on-site parking.

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Brand-New Professional Office Suites
Brand-New Professional Office Suites

4559 Oleander Dr., Myrtle Beach, SC 29577

$5,007/Mo
2,225 sqft 0.85 AC lot

New office suites offer private entrances, prominent signage opportunities, flexible layouts, and ample parking for professional users.

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Office Suite with Executive Center Amenities
Office Suite with Executive Center Amenities

2411 N Oak St. Suite 305-m, Myrtle Beach, SC 29577

$550/Mo
78,000 sqft

A windowless office suite offers access to an on-site gym, reception service, elevators, and 24-hour key-card entry.

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Professional Office Units
Professional Office Units

4559 Oleander Dr., Myrtle Beach, SC 29577

$5,007/Mo
2,225 sqft 0.85 AC lot

Brand-new office suites feature private entrances, signage opportunities, and adaptable layouts.

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Office Suite with Three Offices
Office Suite with Three Offices

618 Chestnut Rd. #204, Myrtle Beach, SC 29572

$1,550/Mo
555 sqft

A second-floor layout includes a reception area, private restroom, and natural light from generous windows.

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New Brick Medical Office Space
New Brick Medical Office Space

116 Professional Park Dr., Conway, SC 29526

$10,634/Mo
3,988 sqft 0.78 AC lot

Clinical rooms, private offices, laboratory space, and dedicated HVAC support a ready-to-lease configuration.

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Three-Room Office Suite
Three-Room Office Suite

2411 N Oak St. Suite 209-b, Myrtle Beach, SC 29577

$2,560/Mo
78,000 sqft

Building amenities include an onsite gym, reception, elevators, and 24-hour key-card entry.

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Executive Office Suite
Executive Office Suite

3955 Highway 17 Bypass, Murrells Inlet, SC 29576

$525/Mo
81 sqft

Compact workspace with shared conference and break facilities; water, sewer, and electric are included.

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Executive Office Suite
Executive Office Suite

2411 N Oak St. Suite 305-p, Myrtle Beach, SC 29577

$560/Mo
78,000 sqft

Suite 305-P includes 24-hour key-card access within a business center offering a gym, reception, and two elevators.

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Office Units with Monument Signage
Office Units with Monument Signage

5187 Horry Dr., Murrells Inlet, SC 29576

$3,670/Mo
1,000 sqft 1.00 AC lot

Divisible professional office space with on-site parking, dedicated break areas, and access to both Highway 17 corridors.

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Horry County, SC Office Spaces Market Trends and Statistics

Explore Office Spaces leasing options in Horry County, SC with 82 listings featured on our commercial real estate exchange. The current inventory includes 731,366 square feet of properties with an estimated lease value of $1,365.

Estimated lease rates for Office Spaces in Horry County, SC begin at $12 SF/Yr, with an average of $25.76 SF/Yr and extend to $98.12 SF/Yr.
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