Greenville County, SC Office Spaces for Rent & Lease

SC, Greenville - E Stone Avenue

17 1St St, Unit 2ND, Greenville, SC 29609

$129-$24,365/Mo

11-2,123 sqft

(972) 764-8885

Flexible workspace in SC, Greenville - E Stone Avenue. Book a tour & get info

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Updated: Mar 24

Piedmont Commercial Office Space

2514 River Road, Piedmont, SC 29673

$1,650/Mo

1,200 sqft

High‑visibility location on a high‑traffic road, ideal for attracting clients and customers.
Convenient access to I‑85 highway, facilitating easy commuting for employees and clients.
Flexible, customizable 1,200 square foot open layout suitable for various business types.
Includes water, trash, and all NNN costs in monthly rent of $1,700.
Modern finishes and on‑site parking create a professional and inviting atmosphere.

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Updated: Jun 3

Lower-Level Office Suite

1322 E Washington Street, Greenville, SC 29607

$1,500/Mo

700 SF office/studio space on the rear lower level in Park Square Center
1 bathroom in the unit; D2 is freshly painted and ready for a new tenant
Asking $1,500 per month with a 2‑year lease; tenant pays all utilities
Tenant provides commercial tenant’s insurance; shared parking is available for all tenants
Building is centrally located in Greenville, SC, blocks from downtown, I‑385, and 2 miles from US‑85

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Renovated Office Suite with ADA Access

413 Vardry Street, Greenville, SC 29601

$2,750/Mo

Newly renovated office suite offers two private offices, two conference rooms, reception, and an ADA bathroom.

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Single-Story Freestanding Office Building

1313A Miller Road, Greenville, SC 29607

$16.50 SF/Yr

4,000 sqft

Functional single-story office layout with multiple private offices, open bullpen space, conference room, and on-site parking.

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Updated Office Suite with Parking

413 Vardry Street, Greenville, SC 29601

$2,550/Mo

Updated office suite with vaulted ceilings, exposed ductwork, multiple private offices, and five dedicated parking spaces.

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Main Street Professional Office Space

200 N Main Street, Greenville, SC 29601

$550/Mo

Newly renovated office spaces overlooking Main Street in Greenville, SC.

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All-Brick One-Level Office Building

413 Vardry Street, Greenville, SC 29601

$800/Mo

All-brick, one-level office space with multiple window offices and a bright, naturally lit lobby.

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Medical Office Suite with Reception

30 Memorial Medical Dr, Greenville, SC 29605

$18 SF/Yr

2,336 sqft

New LVP flooring supports a patient-ready layout with reception, private offices, and accessible restrooms.

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Furnished Office Space Available

552 Memorial Drive Extension, Greer, SC 29651

$585/Mo

Furnished and unfurnished offices with included utilities and amenities.

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Millport at Butler

128 Millport Cir, Unit 200, Greenville, SC 29607

$129-$21,652/Mo

11-2,174 sqft

Flexible workspace in Millport at Butler. Book a tour & get info

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NOMA Tower

220 Main St, Unit 500, Greenville, SC 29601

$129-$22,570/Mo

11-2,002 sqft

Flexible workspace in NOMA Tower. Book a tour & get info

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Downtown Greenville Office Space

22 S Main St, Greenville, SC 29601

$22.50 SF/Yr

10,308 sqft

Turnkey office space with high-end finishes and Main Street views.

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Single-Story Flex Office Warehouse

127 Tanner Rd, Greenville, SC 29607

$15 SF/Yr

31,835 sqft

Single-story office, climate-controlled warehouse, and a detached shop with covered loading and ample parking.

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Premier Greenville Office Complex

37 Villa Rd, Greenville, SC 29615

$19 SF/Yr

1,422 sqft

Variety of office spaces with extensive upgrades and easy access.

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Class A Office Space

110 East Court Street, Greenville, SC 29601

$49.50 SF/Yr

5,024 sqft

Premier office space in Greenville's award-winning downtown.

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Textile Mill Lofts in Greenville

201 Smythe Street, Greenville, SC 29611

$20 SF/Yr

2,035 sqft

Live, work, and play spaces with industrial architecture.

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Main Street Professional Office Spaces

200 North Main Street, Greenville, SC 29601

$550/Mo

900 sqft

Newly renovated office spaces with Main Street views for lease.

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Class A Mixed-Use Redevelopment

400 Augusta Street, Greenville, SC 29601

$28 SF/Yr

3,190 sqft

Located in Greenville’s Historic Westend, easily accessible to major routes.

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Downtown Greenville Office Space Available

101 North Main Street, Greenville, SC 29601

$36.50 SF/Yr

18,457 sqft

Office space for rent in downtown Greenville with amenities.

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Greenville Office Building For Rent

84 Villa Road, Greenville, SC 29615

$21.50 SF/Yr

25,640 sqft

Up to 25,640 SF available near I-385.

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Modern Office Space with Amenities

30 Patewood Drive, Greenville, SC 29615

$28.50 SF/Yr

7,915 sqft

Office space with tenant lounge, fitness center, and food trucks.

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Pleasantburg Drive Office Building

1934 N Pleasantburg Dr, Greenville, SC

$17 SF/Yr

1,800 sqft

1,800 SF office building for lease on 0.48 acres.

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Greer Retail/Office/Medical Space For Rent

1317 West Poinsett Street, Greer, SC

$14 SF/Yr

2,100 sqft

Flexible 2,100 SF space ideal for retail, office, or medical.

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Revitalized Downtown Greenville Retail/Office Space

300 East McBee Avenue, Greenville, SC 29601

$41.50 SF/Yr

14,052 sqft

Prime retail and office spaces in a rejuvenated downtown location.

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