Spartanburg County, SC Medical Office Space for Rent & Lease

Updated: Jun 21

Renovated Fully Furnished Office Building

792 John B White Sr Boulevard, Spartanburg, SC 29306

$2,808/Mo

1,230 SF fully furnished office building, move‑in ready for an office or business tenant
Recently renovated interior with fresh paint, updated lighting, and contemporary finishes throughout
Central heating and central air conditioning for year‑round comfort
Wood flooring with vinyl construction materials
Public sewer service and parking lot parking; includes a porch

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Updated: Mar 7

Premier Medical Office Space Available

1650 Skylyn Drive, Spartanburg, SC 29307

$20 SF/Yr

7,039 sqft $11,731/Mo

Premier Class A medical office space, strategically located on the Mary Black campus, unique to the Spartanburg market.
On‑site wellness amenity suite featuring a fitness gym, swimming pool, and smoothie bar exclusively for building tenants.
Lower NNN fees than comparable properties.
Direct access to the Drayton Mills Trail and proximity to the vibrant Drayton Mills mixed‑use development.
Abundant parking.

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Westside Office/Medical Space Available

225 E Blackstock Rd, Spartanburg, SC

$16 SF/Yr

5,461 sqft $7,281/Mo

5461± sq ft office/medical space for rent.

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Medical Office Space For Rent

3610 Moore Duncan Hwy, Moore, SC 29369

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5,200 sqft

Medical office space with high visibility and easy access.

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Renovated Office Space on Main

705 East Main Street, Duncan, SC 29334

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1,000 sqft

Recently renovated office space with flexible layout in Duncan, SC.

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Spartanburg Medical Office Space Available

478-480 Floyd Rd, Spartanburg, SC

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3,000 sqft

Medical office space for lease with ample parking.

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Class A Medical Office Space

1650 Skylyn Dr, Spartanburg, SC 29307

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Premier medical office space with wellness amenities and convenient location.

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Based on your search, we've compiled 18 Potential Opportunities for your consideration. Besides 7 Active listings in Spartanburg County, SC, we suggest exploring alternatives. Similar 7 Properties for Sales.

Similar Spaces for Sale in Spartanburg County, SC

Consider Similar Space for Sale. We found 7 Spaces matching your search parameters.

Adaptive Retail and Office Site

467 Cross Anchor Rd, Woodruff, SC 29388

$1,150,000

Open-plan commercial layout with excess land for parking or outside storage and a loading dock for practical day-to-day operations.

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Spartanburg Office Building For Sale

130 Dillon Drive, Spartanburg, SC 29307

$1,810,000

7,200 sqft

7,200 SF office building near Spartanburg Medical District.

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Medical/Professional Office Space Available

125 Dillon Dr, Spartanburg, SC 29307

$775,000

10,000 sqft 1.30 AC lot

10,000 SF property near Mary Black Regional Hospital.

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Spartanburg Medical/Office Building For Sale

1770 Skylyn Dr, Spartanburg, SC

$825,000

9,594 sqft 1.21 AC lot

9,594 SF medical/office building near downtown Spartanburg.

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Medical Office Space Available

1241 Boiling Springs Rd, Spartanburg, SC

$430,000

4,645 sqft 0.50 AC lot

4,645 SF medical office space for lease.

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Professional Office/Medical Pads For Sale

108 Burton St, Spartanburg, SC

$150,000

3,500 sqft 0.40 AC lot

Two office/medical pads with utilities, parking, and infrastructure included.

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Versatile Commercial Building Near Hospital

200 Dillon Cir, Spartanburg, SC 29307

$845,000

11,925 sqft

Adaptable commercial building suitable for medical, retail, or storage use.

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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Prime Development Opportunity in Greenville

39 Airpark Ct, Greenville, SC 29607

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1.27 acre interstate-visible land for ground lease or build-to-suit.

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Prime Lexington Outlot Opportunity

3330 Partner Place, Lexington, KY 40503

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Outlot for ground lease or build-to-suit in South Lexington.

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Prime Commercial Lot For Rent

Tift Avenue N, Tifton, GA 31794

$7,500/Mo

0.66 acre commercial lot with high visibility.

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Corner Lot on Highway 72

30472 Highway 72, Madison, AL 35756

$5,000/Mo

1,875 sqft $32 SF/Yr

1.7 acre corner lot zoned for commercial, medical, residential.

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Spartanburg County, SC Medical Office Space Market Trends and Statistics

Explore Medical Office Space leasing options in Spartanburg County, SC with 7 listings featured on our commercial real estate exchange. The current inventory includes 12,500 square feet of properties with an estimated lease value of $36 SF/Yr.

Estimated lease rates for Medical Office Space in Spartanburg County, SC begin at $16 SF/Yr, with an average of $18 SF/Yr and extend to $20 SF/Yr.