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Spartanburg, SC Office Spaces for Lease

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43 properties
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Renovated Furnished Office Units
Updated: Jun 21
Renovated Furnished Office Units

792 John B White Sr Boulevard, Spartanburg, SC 29306

$2,808/Mo
0.56 AC lot
1,230‑square‑foot furnished office property
Recently renovated with updated lighting, LVP, carpet, and contemporary finishes
Flexible office layout with central heating and central air
0.56‑acre site with parking lot and porch
Access to Interstate 26 and Interstate 85
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Industrial Flex Space with Two Buildings
Updated: Jul 25
Industrial Flex Space with Two Buildings

113 Ian Ct, Spartanburg, SC 29306

$12,500/Mo
12,500 sqft 1.95 AC lot
Approximately 12,500 SF of industrial space across two buildings
Approximately 1.95 acres at 113 Ian Court, Spartanburg, SC 29306
Front building includes approximately 4,000 SF of office space
Front building also contains a 6,000‑SF warehouse
Rear building provides an additional 2,500‑SF warehouse
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Spartanburg Storefront Retail/Office Space
Spartanburg Storefront Retail/Office Space

512 E Main St, Spartanburg, SC 29302

$15 SF/Yr
2,046 sqft

Renovated 2,046 SF retail/office space in downtown Spartanburg.

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Historic Mill Office Space Available
Historic Mill Office Space Available

1802 Drayton Road, Suite 140B, Spartanburg, SC 29307

$16 SF/Yr
53,571 sqft

Creative office space in a vibrant mixed-use community.

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Flex Space with Conditioned Warehouse
Flex Space with Conditioned Warehouse

1095 Southport Rd, Spartanburg, SC 29306

$8 SF/Yr
24,000 sqft

Industrial property combining office accommodation with conditioned warehouse and manufacturing space.

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Retail Space Near Downtown
Retail Space Near Downtown

151 John B White Sr Boulevard, Spartanburg, SC 29306

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1,150 sqft

Unit B accommodates retail or office operations in a compact commercial setting.

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Historic Office Building for Rent
Historic Office Building for Rent

571 East Main Street, Spartanburg, SC 29302

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4,688 sqft 0.48 AC lot

Renovated historic building with multiple rooms, suited for professional office use, with street parking available.

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Class A Office Suite
Class A Office Suite

149B West Main Street, Spartanburg, SC 29306

$30 SF/Yr

Class A suite with private offices and flexible configuration, featuring top-floor views in downtown Morgan Square.

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Office Unit with Private Offices
Office Unit with Private Offices

481 S. Pine Street, Spartanburg, SC 29302

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440 sqft

Compact office suite with shared reception, kitchenette, restroom, and included utilities.

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Office Space Near I-26
Office Space Near I-26

208 Oak Forest Rd, Spartanburg, SC 29301

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3,600 sqft

3,600+/- SF office space with laydown yard near I-26.

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Retail Endcap with Drive-Thru
Retail Endcap with Drive-Thru

550 S Church St, Spartanburg, SC 29306

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1,400 sqft

Available endcap suite features a drive-thru and is fully sprinklered within a multi-suite shopping center.

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Class A Medical Office Suite
Class A Medical Office Suite

1650 Skylyn Dr, Spartanburg, SC 29307

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2,132 sqft

NNN-leased Class A medical office suite with ample parking and an on-site gym.

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Retail or Office Suite Units
Retail or Office Suite Units

601 John B White Sr Blvd, Spartanburg, SC 29306

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1,200 sqft

Two adjacent suites, B and C, each about 1,200 SF, suited for retail or office use.

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Move-in Ready Furnished Office Space
Move-in Ready Furnished Office Space

792 John B White Sr Boulevard, Spartanburg, SC 29306

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Recently renovated, fully furnished office building in a prime location.

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Office Suite with Testing Facility
Office Suite with Testing Facility

105 Corporate Dr, Spartanburg, SC 29303

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1,350 sqft

Move-in-ready office suite with testing facility and a floor plan that can be modified to fit your operation.

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Office Unit in 1925 Building
Office Unit in 1925 Building

485 S PINE ST, Spartanburg, SC 29302

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2,484 sqft

Office space within a building constructed in 1925.

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Regus Coworking Space with Meeting Rooms
Regus Coworking Space with Meeting Rooms

500 W Main St 2nd Floor, Spartanburg, SC 29301

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Regus coworking and private office space on the second floor with fully equipped meeting rooms.

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Westside Office/Medical Space Available
Westside Office/Medical Space Available

225 E Blackstock Rd, Spartanburg, SC

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5,461 sqft 0.94 AC lot

5461± sq ft office/medical space for rent.

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Mixed-Use Building with Outdoor Area
Mixed-Use Building with Outdoor Area

500 W Main St, Spartanburg, SC 29301

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10,992 sqft

Built in 1916 and renovated 2023–2024, featuring retail, restaurant, office, and entertainment space plus large rear outdoor area.

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Renovated Historic Mixed-Use Building
Renovated Historic Mixed-Use Building

500 W Main St, Spartanburg, SC 29301

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4,388 sqft

Historic building renovated 2023–2024 with retail, restaurant, office, and entertainment space plus ample parking.

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Renovated Office Building with Parking
Renovated Office Building with Parking

500 W Main St, Spartanburg, SC 29301

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5,061 sqft

Office component in a mixed-use building renovated 2023–2024 with ample parking and multiple ingress/egress options.

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Three-Level Professional Office Building
Three-Level Professional Office Building

291 S. Pine Street, Spartanburg, SC 29301

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Professional office building with three levels, multiple conference rooms, outdoor patio, and on-site parking for 38 vehicles.

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Spartanburg Office Space For Rent
Spartanburg Office Space For Rent

135 West Main Street, Spartanburg, SC

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1,700 sqft 0.08 AC lot

Office space available for rent in Spartanburg, SC.

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Private Office Suites
Private Office Suites

7931 Valley Falls Rd, Spartanburg, SC 29303

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Single-story workspace offers individual offices plus shared reception and conference facilities for a professional client experience.

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Spartanburg, SC Office Spaces Lease Rates & Market Statistics

Explore 43 Office Spaces for lease in Spartanburg, SC on Realmo, a commercial real estate exchange covering the Spartanburg area. The current inventory totals 169,150 square feet of properties — an average of ~3,950 SF per listing.

Office Spaces lease rates in Spartanburg range from $8 SF/Yr at the entry level to $30 SF/Yr at the top of the market, averaging $16.20 SF/Yr. That's a 4x spread between entry-level and premium space, making side-by-side comparison of asking rents and lease terms essential. The local average of $16.20 SF/Yr is 30% below the South Carolina state average of $23.14 SF/Yr.

Spartanburg accounts for 74% of the 58 office spaces currently available across Spartanburg County, where nearby markets include Boiling Springs and Moore. By space type, the market includes 35 office units, 5 office buildings and 3 medical office space listings.

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