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    South Carolina Office Spaces for Lease

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    Greenville, SC Columbia, SC Charleston, SC Myrtle Beach, SC North Charleston, SC Spartanburg, SC Rock Hill, SC Mount Pleasant, SC
    981 properties
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    Fully Serviced Business Solutions at SC, Columbia - Williams Street. Contact us today to book a tour!
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    Fully Serviced Business Solutions at SC, Summerville - 700 Nexton Square Drive. Contact us today to book a tour!
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    Single-Room Office Unit
    Updated: Aug 5
    Single-Room Office Unit

    918 Houndslake Drive, Aiken, SC 29803

    $534/Mo
    7,076 sqft
    7,076‑square‑foot multi‑tenant office building
    Single‑room office unit with shared waiting and reception areas
    Lower‑level common kitchen, shared bathrooms, and shower
    Utilities and shared internet included
    Laundry facility available for tenant use
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    Medical Office Space with Multiple Offices
    Updated: Jul 31
    Medical Office Space with Multiple Offices

    407 N Salem Avenue, Sumter, SC 29150

    $7,337/Mo
    7,337 sqft 1.13 AC lot
    7,337‑square‑foot medical office property
    Layout includes numerous rooms, offices, and storage areas
    1.13‑acre site at 407 N Salem Avenue, Sumter, SC 29150
    Brick and block construction with tile and carpet flooring
    Central air conditioning and heat pump heating
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    Nine-Room Office Building
    Nine-Room Office Building

    118 Park Avenue SE, Aiken, SC 29801

    $2,800/Mo
    2,522 sqft 0.02 AC lot

    Downtown space includes two bathrooms and is zoned Com for office or professional service use.

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    Flexible workspace at SC, Charleston - Fairchild Street. Contact us today to book a tour!
    Flexible workspace at SC, Charleston - Fairchild Street. Contact us today to book a tour!

    125 Fairchild St, Unit 2ND, Charleston, SC 29492

    16 available spaces from 11 to 2,056 sqft
    $129-$25,702/Mo per office

    Discover many ways to work your way in Flexible workspace at SC, Charleston - Fairchild Street. Contact us today to book a tour!

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    New Mixed-Use Space
    New Mixed-Use Space

    5100 Highway 17 Bypass, Murrells Inlet, SC 29576

    $3,125/Mo
    2,500 sqft 1.90 AC lot

    New construction supports flexible medical, professional office, and specialty retail configurations with direct exposure on the Highway 17 Bypass.

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    Three-Office Suite
    Three-Office Suite

    1890 Huntsman Drive, Aiken, SC 29803

    $1,600/Mo
    945 sqft

    A reception area, shared workroom, and restroom serve the office layout.

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    Office Suite with Private Restroom
    Office Suite with Private Restroom

    618 Chestnut Rd., Myrtle Beach, SC 29572

    $1,550/Mo
    555 sqft 0.44 AC lot

    The second-floor layout includes a reception area, three offices, and a restroom within the suite.

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    Coworking and Private Offices with Flexible Terms at Millport at Butler. Contact us today to book a tour!
    Coworking and Private Offices with Flexible Terms at Millport at Butler. Contact us today to book a tour!

    128 Millport Cir, Unit 200, Greenville, SC 29607

    16 available spaces from 11 to 2,174 sqft
    $129-$21,652/Mo per office

    Flexible workspace in Millport at Butler. Book a tour & get info

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    Dental Medical Office Suite
    Dental Medical Office Suite

    417 W Cheves Street, Florence, SC 29501

    $3,000/Mo
    1,850 sqft

    The layout includes operatories, laboratory space, reception areas, and a private office.

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    Office Suite Under Renovation
    Office Suite Under Renovation

    1886 Huntsman Drive, Aiken, SC 29803

    $1,600/Mo
    945 sqft

    Zoning allows the space to serve office or retail uses.

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    Fully Serviced Workspace Options at SC, Columbia - 1501 Main St. Contact us today to book a tour!
    Fully Serviced Workspace Options at SC, Columbia - 1501 Main St. Contact us today to book a tour!

    1501 Main St, Unit 501, Columbia, SC 29201

    16 available spaces from 11 to 2,011 sqft
    $129-$17,909/Mo per office

    Flexible workspace in SC, Columbia - 1501 Main St. Book a tour & get info

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    Medical Office Suite in Professional Park
    Medical Office Suite in Professional Park

    710 21st Ave. N, Myrtle Beach, SC 29577

    $1,166/Mo
    560 sqft 0.16 AC lot

    The space is part of a multi-building office park with medical and professional units.

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    Renovated Medical Office Suite
    Renovated Medical Office Suite

    4310 Highway 17 Business, Murrells Inlet, SC 29576

    $8,000/Mo
    3,557 sqft 3.00 AC lot

    Recently renovated Class A space with shared patient amenities, dedicated elevators, and services included in the lease package.

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    Fully Serviced Business Solutions at Faber Center. Contact us today to book a tour!
    Fully Serviced Business Solutions at Faber Center. Contact us today to book a tour!

    4000 Faber Place Dr, Unit 300, North Charleston, SC 29405

    16 available spaces from 11 to 2,045 sqft
    $129-$22,234/Mo per office

    Flexible workspace in Faber Center. Book a tour & get info

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    Medical Office Suite
    Medical Office Suite

    710 21st Ave. N, Myrtle Beach, SC 29577

    $2,410/Mo
    1,157 sqft 0.16 AC lot

    A medical and professional office unit is available within a multi-building office park.

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    Executive Office Suite
    Executive Office Suite

    1012 NW 16th Ave., Surfside Beach, SC 29575

    $500/Mo per office
    140 sqft 0.83 AC lot

    A private office rental includes shared conference-room access, utilities, internet, and around-the-clock building access.

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    Flexible Workspace Solutions at Fountian Park. Contact us today to book a tour!
    Flexible Workspace Solutions at Fountian Park. Contact us today to book a tour!

    331 Main St, Unit 200, Rock Hill, SC 29730

    16 available spaces from 11 to 2,254 sqft
    $129-$29,257/Mo per office

    Flexible workspace in Fountian Park. Book a tour & get info

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    One-Room Office Unit
    One-Room Office Unit

    918 Houndslake Drive, Aiken, SC 29803

    $534/Mo
    120 sqft 2.07 AC lot

    Utilities and shared internet are included, with common reception areas and a lower-level kitchen.

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    Flexible workspace at NOMA Tower. Contact us today to book a tour!
    Flexible workspace at NOMA Tower. Contact us today to book a tour!

    220 Main St, Unit 500, Greenville, SC 29601

    16 available spaces from 11 to 2,002 sqft
    $129-$22,570/Mo per office

    Flexible workspace in NOMA Tower. Book a tour & get info

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    Single-Story Professional Office Units
    Single-Story Professional Office Units

    212 Newberry Street NW, Aiken, SC 29801

    $4,800/Mo
    3,214 sqft

    Configured for professional users with private rooms, meeting space, support areas, and on-site parking.

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    SC, Columbia - Stoneridge Drive
    SC, Columbia - Stoneridge Drive

    140 Columbia Ave, Columbia, SC 29210

    16 available spaces from 11 to 2,071 sqft
    $129-$23,624/Mo per office

    Flexible workspace in SC, Columbia - Stoneridge Drive. Book a tour & get info

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    Second-Floor Office Unit
    Second-Floor Office Unit

    870 Inlet Square Dr., Murrells Inlet, SC 29576

    $1,450/Mo
    1,246 sqft 0.59 AC lot

    HC-zoned office space positioned near major commercial and recreational destinations in Murrells Inlet.

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    Medical Office Space with Drop-Off Area
    Medical Office Space with Drop-Off Area

    230 Giles Dr, Boiling Springs, SC 29316

    $6,730/Mo
    6,730 sqft 1.25 AC lot

    Private offices, shared work areas, and a dedicated vehicle drop-off area provide a flexible existing layout.

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    First-Floor Professional Office Suite
    First-Floor Professional Office Suite

    3876 Renee Dr., Myrtle Beach, SC 29579

    $3,920/Mo
    2,352 sqft 0.56 AC lot

    Eight private offices, two conference rooms, and a reception area create a defined workspace layout.

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    South Carolina Office Spaces Market Trends and Statistics

    Explore Office Spaces leasing options in South Carolina with 981 listings featured on our commercial real estate exchange. The current inventory includes 7,972,574 square feet of properties with an estimated lease value of $7,440.

    Estimated lease rates for Office Spaces in South Carolina begin at $1.04 SF/Yr, with an average of $24.16 SF/Yr and extend to $200 SF/Yr.
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