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    South Carolina Hotels for Lease

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    Columbia, SC Greenville, SC Charleston, SC
    Historic Mixed-Use Building on King
    $35 SF/Yr
    10,673 SF

    Historic Mixed-Use Building on King

    438 King St, Charleston, SC 29403

    Renovated mixed-use building in Charleston's Upper King Street corridor.

    • Prime location in the heart of Charleston's historic Upper King Street corridor, next to Hall's Chophouse.
    • Rare amenity of 18 on‑site parking spaces.
    • Large ±10,673 square foot mixed‑use building suitable for retail, office, restaurant, or hospitality.
    • Classic architectural character with modern updates, including large storefront windows, high ceilings, hardwood floors, and historic detailing.
    • Each floor features access to outdoor patio or porch space.
    Updated: Nov 22, 2025
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    Hotel Near Downtown Charleston
    $1.00 SF/Yr
    5,000 SF

    Hotel Near Downtown Charleston

    4213 Savannah Hwy, Ravenel, SC 29470

    Hotel property for lease near downtown Charleston.

    • Advantageous position near downtown Charleston
    • Direct frontage on Savannah Highway
    • Attractive haven for tourists
    • Attractive haven for business travelers
    • Peaceful retreat
    Updated: Nov 21, 2025
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    Prime Outparcel Opportunities in Florence
    Contact for pricing

    Prime Outparcel Opportunities in Florence

    Outparcels available at I-95 interchange, ideal for hotels, restaurants.

    2939 N Williston Rd, Florence, SC 29506
    View details
    Based on your search, we've compiled 34 Potential Opportunities for your consideration. Besides 3 Active listings in South Carolina, we suggest exploring alternatives. Similar 31 Properties for Sales.

    Explore Similar Spaces for Sale in South Carolina

    Consider Similar Space for Sale. We found 31 Spaces matching your search parameters.

    Downtown Historic District Mixed-Use Property
    $199,900
    8,400 SF

    Downtown Historic District Mixed-Use Property

    Two-story, mixed-use property in Gaffney's historic district.

    314,316, N Limestone Street, Gaffney, SC 29340
    View details
    Historic Edgefield Commercial Opportunity
    $549,000
    6,000 SF

    Historic Edgefield Commercial Opportunity

    Versatile commercial property with retail and rental income potential.

    303 Main Street, Edgefield, SC 29824
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    Historic Edgefield Commercial Opportunity
    $549,000
    6,000 SF

    Historic Edgefield Commercial Opportunity

    Dual income property in historic downtown Edgefield.

    303 Main Street, Edgefield, SC 29824
    View details
    Commercial Land Near Interstate SC
    $450,000
    1.42 Acres

    Commercial Land Near Interstate SC

    Commercial land suitable for restaurant, hotel, or retail establishment.

    18330 Highway 72 East, Clinton, SC 29325
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    Prime Commercial Land I-26 Exit
    $450,000
    1.42 Acres

    Prime Commercial Land I-26 Exit

    Commercial land suitable for restaurant, hotel, or retail development.

    18330 Highway 72 East, Clinton, SC 29325
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    Oceanfront Hospitality Property with Restaurant
    $7,600,000
    23,336 SF

    Oceanfront Hospitality Property with Restaurant

    Oceanfront 54-unit building with commercial restaurant space and parking lot.

    606 N Ocean Blvd., Myrtle Beach, SC 29577
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    Renovated Hotel Near Myrtle Beach
    $5,490,000
    22,092 SF

    Renovated Hotel Near Myrtle Beach

    Newly renovated 63-room hotel near Myrtle Beach SkyWheel.

    507 -509 Ocean Blvd. N, Myrtle Beach, SC 29577
    View details
    Daniel Island Deepwater Residential Enclave
    $8,250,000
    1.66 Acres

    Daniel Island Deepwater Residential Enclave

    Rare waterfront acreage suitable for residential or commercial development.

    1995 Daniel Island Drive, Charleston, SC 29492
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    I-95 Development Opportunity, Yemassee
    $695,000
    8.80 Acres

    I-95 Development Opportunity, Yemassee

    8.8 acres zoned UD2 with I-95 frontage.

    Us-21, Yemassee, SC 29945
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    Clemson Land for Multifamily Development
    $1,299,774
    7.66 Acres

    Clemson Land for Multifamily Development

    7+ acres in Clemson, SC, ideal for multifamily or hotel development.

    00 76 Highway, Clemson, SC 29631
    View details
    Beaufort Hospitality Property for Sale
    $4,000,000

    Beaufort Hospitality Property for Sale

    Hospitality property in historic Beaufort, South Carolina, near Sea Islands.

    109 Old Salem Rd, Beaufort, SC 29902
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    Beaufort Hospitality Property For Sale
    $4,000,000

    Beaufort Hospitality Property For Sale

    Hospitality property in historic Beaufort, South Carolina, near Sea Islands.

    109 Old Salem Rd, Beaufort, SC 29902
    View details
    Prime Commercial Acreage For Sale
    $3,500,000
    4.33 Acres

    Prime Commercial Acreage For Sale

    4.3 acres in Seneca, SC, ideal for retail or hospitality.

    1018 E. North 1st Street, Seneca, SC 29678
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    Lagoon View Sanibel Floor Plan
    Contact for pricing

    Lagoon View Sanibel Floor Plan

    First floor unit with golf and Westin Hotel amenities.

    14 Wimbledon Court 807-4, Hilton Head Island, SC 29928
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    Downtown Columbia Development Opportunity
    Contact for pricing
    90,402 SF

    Downtown Columbia Development Opportunity

    Landmark building for redevelopment in Columbia's Central Business District.

    1339 Main Street, Columbia, SC 29201
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    Neoclassical Mansion Event Venue
    $1,350,000
    9,440 SF

    Neoclassical Mansion Event Venue

    Commercial

    120 e Liberty St, Unit 120, Sumter, SC 29150
    View details
    Oceanfront Hotel in Myrtle Beach
    $1,100,000

    Oceanfront Hotel in Myrtle Beach

    40-room hotel with renovated rooms and kitchenettes.

    2711 S Ocean Blvd, Myrtle Beach, SC 29577
    View details
    Entertainment and Mixed-Use Development Site
    Contact for pricing

    Entertainment and Mixed-Use Development Site

    50+ acre development site with high visibility and traffic.

    Interstate 85 & Pelham Road, Greenville, SC 29615
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    Oceanfront Condo with Rental Potential
    $88,000

    Oceanfront Condo with Rental Potential

    Updated oceanfront condo in Myrtle Beach with strong rental demand.

    1501 S Ocean Blvd. #1115, Myrtle Beach, SC 29577
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    Oceanfront Hotel in Myrtle Beach
    Contact for pricing

    Oceanfront Hotel in Myrtle Beach

    42-room oceanfront hotel with recent renovations and strong tourism.

    1901 S Ocean Blvd, Myrtle Beach, SC 29577
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    50-Room Hotel Near I-95
    Contact for pricing

    50-Room Hotel Near I-95

    Hotel with pool and breakfast area near shopping and dining.

    817 Radford Blvd, Dillon, SC 29536
    View details

    South Carolina Hotels Leasing Opportunities Market Analysis

    Explore Hotels leasing options in South Carolina with 3 listings featured on our commercial real estate exchange. The current inventory includes 464,915,880 square feet of properties with an estimated lease value of $35 SF/Yr.

    Estimated lease rates for Hotels in South Carolina begin at $35 SF/Yr, with an average of $35 SF/Yr and extend to $35 SF/Yr.
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