Add Listing
    For Lease
    • For Sale
    • For Lease
    • Recently Sold
    • Property Lookup
    • Brokers
    Medical Space
    1
    • Retail
    • Restaurant
    • Office
    • Coworking
    • Medical Space
    • Automotive
    • Industrial
    • Warehouse
    • Flex
    • Hospitality
    • Sports & Entertainment
    • Specialty
    Price
    Price range
    $
    $
    Size
    Property size / sq.ft.
    AI Search

    Meet Realmo: The Largest Hub
    of Commercial Real     Estate in the US

    Over 1 million active listings and over 150 million property profiles

    Lexington County, SC Medical Office Space for Lease

    List
    Map
    Columbia, SC Greenville, SC Charleston, SC
    30 results
    Two-Story Office Building For Rent
    $16 SF/Yr
    3,960 SF

    Two-Story Office Building For Rent

    123 Lawand Dr, Columbia, SC 29210

    Two-story office building with flexible layout in central Columbia.

    • Excellent central Columbia location with easy access to I‑20/I‑26 interchange.
    • Highly functional and flexible layout suitable for various business uses (office, medical, professional services).
    • Potential to function as up to three separate office suites, accommodating single or multiple tenants.
    • ±3,960 SF two‑story masonry office building.
    • Move‑in‑ready condition.
    Updated: Mar 20
    View details
    West Columbia Office/Medical Suite
    $18 SF/Yr
    12,000 SF

    West Columbia Office/Medical Suite

    3618 Sunset Blvd., West Columbia, SC 29169

    Office/medical suite for lease near Lexington Medical Hospital.

    • Prime Location: Minutes from Lexington Medical Hospital, I‑26, and I‑20, offering convenient access.
    • Excellent Signage and Visibility: Prominent monument and façade signage at a signalized intersection on Hwy. 378.
    • Versatile Layout: Suite C (± 1,650 SF) with 5 private offices, conference room, breakroom, and restroom, suitable for various users.
    • Convenient Parking: Dedicated parking available for tenants and customers.
    • Strategic Location: Situated off Sunset Blvd. (Hwy. 378) in West Columbia.
    Updated: Jan 27
    View details
    Medical Office Space For Lease
    $20 SF/Yr
    7,659 SF

    Medical Office Space For Lease

    Medical office space in prime healthcare corridor location.

    161 Medical Circle, West Columbia, SC 29169
    View details
    Downtown Columbia Office Space Available
    $17 SF/Yr
    8,584 SF

    Downtown Columbia Office Space Available

    Office spaces for lease in downtown Columbia, South Carolina.

    1901 Gadsden Street, Columbia, SC 29201
    View details
    Columbia Office/Medical Space For Lease
    $21 SF/Yr
    20,822 SF

    Columbia Office/Medical Space For Lease

    Office and medical space available for lease in Columbia, SC.

    120 & 122 Highland Center Dr., Columbia, SC 29203
    View details
    Medical Office Complex For Rent
    $28 SF/Yr
    126,002 SF

    Medical Office Complex For Rent

    Medical office complex in Columbia's Central Business District, renovated.

    2750 Laurel St., 2601 Laurel St. & 1655 Bernardin Ave., Columbia, SC 29206
    View details
    Standalone Office Building Suite
    $22 SF/Yr
    4,000 SF

    Standalone Office Building Suite

    Office suite with reception, offices, bathrooms, and break room.

    300 Rice Meadow Way, Columbia, SC
    View details
    Move-in Ready Office Space
    $15 SF/Yr
    4,000 SF

    Move-in Ready Office Space

    4,000 SF office space for lease in Columbia, SC.

    144 Leisure Ln, Columbia, SC
    View details
    Cayce Office/Medical Space Available
    $20 SF/Yr
    5,670 SF

    Cayce Office/Medical Space Available

    5,670 SF building suitable for office or medical use.

    1105 State St, Cayce, SC
    View details
    Medical Office Space Available
    Contact for pricing
    39,722 SF

    Medical Office Space Available

    Accessible medical office space in a growing Columbia corridor.

    3221, 3223, 3225, & 3231 Sunset Blvd., West Columbia, SC 29169
    View details
    Retail, Restaurant, or Medical Office
    Contact for pricing
    24,000 SF

    Retail, Restaurant, or Medical Office

    Located in a Publix-anchored shopping center with high visibility.

    2800 Rosewood Dr., Columbia, SC 29205
    View details
    Dental Space Available for Rent
    $24 SF/Yr
    2,606 SF

    Dental Space Available for Rent

    Turn-key dental space with equipment in Lexington, SC.

    108 Palmetto Park Blvd, Lexington, SC
    View details
    Renovated Medical Office Space Available
    $25 SF/Yr
    43,000 SF

    Renovated Medical Office Space Available

    10,000 SF renovated medical office space for lease.

    1777 St. Julian Place, Columbia, SC 29204
    View details
    Move-in Ready Medical Office Space
    $15 SF/Yr
    2,466 SF

    Move-in Ready Medical Office Space

    Medical office space for lease in Columbia's CBD.

    1538 Main St, Columbia, SC
    View details
    9,000 SF Office Building For Lease
    $8 SF/Yr

    9,000 SF Office Building For Lease

    9,000 SF Office Building For Lease +$8/sqft

    110 Sparkman Dr, Columbia, SC 29209
    View details
    Office Suite in Medical Corridor
    $19 SF/Yr
    3,566 SF

    Office Suite in Medical Corridor

    Office suite with private offices near Lexington Medical Center.

    3634 Sunset Blvd, W, Columbia, SC
    View details
    Medical/Office Space Near Veterans Hospital
    $10 SF/Yr
    800 SF

    Medical/Office Space Near Veterans Hospital

    800 SF medical/office space with ample parking, easy access.

    200 Byron Rd, Columbia, SC
    View details
    Highland Center Office Space Available
    $21 SF/Yr
    7,000 SF

    Highland Center Office Space Available

    Office and medical space available for lease in Columbia.

    122 Highland Center Dr, Columbia, SC
    View details
    Medical Office Complex For Rent
    $28 SF/Yr
    1,797 SF

    Medical Office Complex For Rent

    Medical office complex in Columbia's Central Business District.

    2601 Laurel St, Columbia, SC
    View details
    Forest Acres Office Space Available
    $17 SF/Yr
    4,106 SF

    Forest Acres Office Space Available

    Office space for rent in the heart of Forest Acres.

    4700 Forest Dr, Columbia, SC
    View details
    Renovated Medical Space Available
    Contact for pricing
    2,865 SF

    Renovated Medical Space Available

    Renovated medical Class A space with convenient access.

    1012 Calhoun St, Columbia, SC
    View details
    Class A Medical Office Building
    Contact for pricing
    5,004 SF

    Class A Medical Office Building

    Medical office building near MUSC Health Columbia Medical Center.

    2611 Forest Dr, Columbia, SC 29204
    View details
    Medical Office Space For Rent
    Contact for pricing

    Medical Office Space For Rent

    Professional second-floor medical office space in Columbia, SC.

    710 Rabon Rd, Columbia, SC 29203
    View details
    New Mixed-Use Building For Lease
    Contact for pricing
    14,660 SF

    New Mixed-Use Building For Lease

    New mixed-use building in thriving retail corridor available for lease.

    1514 Brentwood Dr, Columbia, SC 29206
    View details

    Lexington County, SC Medical Office Space Leasing Opportunities Market Analysis

    Explore Medical Office Space leasing options in Lexington County, SC with 30 listings featured on our commercial real estate exchange. The current inventory includes 493,099,200 square feet of properties with an estimated lease value of $50 SF/Yr.

    Estimated lease rates for Medical Office Space in Lexington County, SC begin at $15 SF/Yr, with an average of $16 SF/Yr and extend to $20 SF/Yr.
    List
    Map

    Medical Office Space by market

    Browse Medical Office Space for Lease Near Lexington, SC

    Popular Categories

    Select Neighborhood

    Google sign-in failed. Please try again or use another login method.
    Sign Up Successful!
    You now have access to more from Realmo!