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    Lexington County, SC Medical Office Space for Lease

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    Greenville, SC Columbia, SC Charleston, SC
    27 results
    Two-Story Office Building For Rent
    $16 SF/Yr
    3,960 SF

    Two-Story Office Building For Rent

    123 Lawand Dr, Columbia, SC 29210

    Two-story office building with flexible layout in central Columbia.

    • Excellent central Columbia location with easy access to I‑20/I‑26 interchange.
    • Highly functional and flexible layout suitable for various business uses (office, medical, professional services).
    • Potential to function as up to three separate office suites, accommodating single or multiple tenants.
    • ±3,960 SF two‑story masonry office building.
    • Move‑in‑ready condition.
    Updated: Mar 20
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    West Columbia Office/Medical Suite
    $18 SF/Yr
    12,000 SF

    West Columbia Office/Medical Suite

    3618 Sunset Blvd., West Columbia, SC 29169

    Office/medical suite for lease near Lexington Medical Hospital.

    • Prime Location: Minutes from Lexington Medical Hospital, I‑26, and I‑20, offering convenient access.
    • Excellent Signage and Visibility: Prominent monument and façade signage at a signalized intersection on Hwy. 378.
    • Versatile Layout: Suite C (± 1,650 SF) with 5 private offices, conference room, breakroom, and restroom, suitable for various users.
    • Convenient Parking: Dedicated parking available for tenants and customers.
    • Strategic Location: Situated off Sunset Blvd. (Hwy. 378) in West Columbia.
    Updated: Jan 27
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    Medical Office Space For Lease
    $20 SF/Yr
    7,659 SF

    Medical Office Space For Lease

    Medical office space in prime healthcare corridor location.

    161 Medical Circle, West Columbia, SC 29169
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    Columbia Office/Medical Space For Lease
    $21 SF/Yr
    20,822 SF

    Columbia Office/Medical Space For Lease

    Office and medical space available for lease in Columbia, SC.

    120 & 122 Highland Center Dr., Columbia, SC 29203
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    Medical Office Complex For Rent
    $28 SF/Yr
    126,002 SF

    Medical Office Complex For Rent

    Medical office complex in Columbia's Central Business District, renovated.

    2750 Laurel St., 2601 Laurel St. & 1655 Bernardin Ave., Columbia, SC 29206
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    Standalone Office Building Suite
    $22 SF/Yr
    4,000 SF

    Standalone Office Building Suite

    Office suite with reception, offices, bathrooms, and break room.

    300 Rice Meadow Way, Columbia, SC
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    Move-in Ready Office Space
    $15 SF/Yr
    4,000 SF

    Move-in Ready Office Space

    4,000 SF office space for lease in Columbia, SC.

    144 Leisure Ln, Columbia, SC
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    Cayce Office/Medical Space Available
    $20 SF/Yr
    5,670 SF

    Cayce Office/Medical Space Available

    5,670 SF building suitable for office or medical use.

    1105 State St, Cayce, SC
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    Move-in Ready Medical Office Space
    $20 SF/Yr
    2,466 SF

    Move-in Ready Medical Office Space

    Medical office space for lease in Columbia's CBD.

    1538 Main St, Columbia, SC
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    Retail, Restaurant, or Medical Office
    Contact for pricing
    24,000 SF

    Retail, Restaurant, or Medical Office

    Located in a Publix-anchored shopping center with high visibility.

    2800 Rosewood Dr., Columbia, SC 29205
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    Dental Space Available for Rent
    $24 SF/Yr
    2,606 SF

    Dental Space Available for Rent

    Turn-key dental space with equipment in Lexington, SC.

    108 Palmetto Park Blvd, Lexington, SC
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    Office Suite in Medical Corridor
    $19 SF/Yr
    3,566 SF

    Office Suite in Medical Corridor

    Office suite with private offices near Lexington Medical Center.

    3634 Sunset Blvd, W, Columbia, SC
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    Medical Office Space Available
    Contact for pricing
    39,722 SF

    Medical Office Space Available

    Accessible medical office space in a growing Columbia corridor.

    3221, 3223, 3225, & 3231 Sunset Blvd., West Columbia, SC 29169
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    Medical/Office Space Near Veterans Hospital
    $10 SF/Yr
    800 SF

    Medical/Office Space Near Veterans Hospital

    800 SF medical/office space with ample parking, easy access.

    200 Byron Rd, Columbia, SC
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    9,000 SF Office Building For Lease
    $8 SF/Yr

    9,000 SF Office Building For Lease

    9,000 SF Office Building For Lease +$8/sqft

    110 Sparkman Dr, Columbia, SC 29209
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    Class A Medical Office Space
    Contact for pricing

    Class A Medical Office Space

    Highly visible medical office location in Irmo, South Carolina.

    1600 Lake Murray Blvd, Columbia, SC 29212
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    Highland Center Office Space Available
    $21 SF/Yr
    7,000 SF

    Highland Center Office Space Available

    Office and medical space available for lease in Columbia.

    122 Highland Center Dr, Columbia, SC
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    Medical Office Complex For Rent
    $28 SF/Yr
    1,797 SF

    Medical Office Complex For Rent

    Medical office complex in Columbia's Central Business District.

    2601 Laurel St, Columbia, SC
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    New Mixed-Use Building For Lease
    $33 SF/Yr
    14,660 SF

    New Mixed-Use Building For Lease

    New mixed-use building in thriving retail corridor available for lease.

    1514 Brentwood Dr, Columbia, SC 29206
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    Forest Acres Office Space Available
    $17 SF/Yr
    4,106 SF

    Forest Acres Office Space Available

    Office space for rent in the heart of Forest Acres.

    4700 Forest Dr, Columbia, SC
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    Medical Office Space For Rent
    $28 SF/Yr

    Medical Office Space For Rent

    Professional second-floor medical office space in Columbia, SC.

    710 Rabon Rd, Columbia, SC 29203
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    Renovated Medical Space Available
    Contact for pricing
    2,865 SF

    Renovated Medical Space Available

    Renovated medical Class A space with convenient access.

    1012 Calhoun St, Columbia, SC
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    Class-A Office/Medical Space Available
    $22 SF/Yr
    3,100 SF

    Class-A Office/Medical Space Available

    Class-A office/medical space for lease in Northeast Columbia.

    1074 Pinnacle Point Dr, Columbia, SC
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    Class A Medical Office Building
    Contact for pricing
    5,004 SF

    Class A Medical Office Building

    Medical office building near MUSC Health Columbia Medical Center.

    2611 Forest Dr, Columbia, SC 29204
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    Lexington County, SC Medical Office Space Leasing Opportunities Market Analysis

    Explore Medical Office Space leasing options in Lexington County, SC with 27 listings featured on our commercial real estate exchange. The current inventory includes 277,509 square feet of properties with an estimated lease value of $412 /Mo.

    Estimated lease rates for Medical Office Space in Lexington County, SC begin at $10 SF/Yr, with an average of $20 SF/Yr and extend to $33 SF/Yr.
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