Greenville County, SC Medical Office Space for Rent & Lease

Updated: Jun 5

Medical Office Suite with Reception

30 Memorial Medical Dr, Greenville, SC 29605

$18 SF/Yr

2,336 sqft

2,336 SF office space with brand new LVP flooring
Patient‑ready layout with large reception area and 10 private offices
Includes 2 accessible bathrooms
Phlebotomist on site
Next door to Kidney Clinic

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Updated: Nov 25, 2025

Greenville Office/Medical Space For Rent

20 Creekview Ct, Greenville, SC

$1,275/Mo

1,005 sqft

Located in the desirable Roper Mountain area.
Ideal for Medical or Office use.
Plenty of Parking available.
Suitable for Mental Health/Alternative Medicine or General Office Use.
Features a Medical Sink and Cabinetry.

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Medical Office Space For Lease

3535 Pelham Road, Greenville, SC 29615

$13.95 SF/Yr

8,000 sqft

Medical office space for lease in Greenville, South Carolina.

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Medical Office Space For Lease

10 Enterprise Blvd., Greenville, SC 29615

$26.50 SF/Yr

45,200 sqft

Medical office space near Prisma Health Patewood & Bon Secours.

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Greenville Medical Office Space

3807 White Horse Rd, Greenville, SC

$30 SF/Yr

2,600 sqft

Modern medical office space available for lease in Greenville, SC.

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Medical Office Near Greenville Memorial

8 Memorial Medical Ct, Greenville, SC

$18 SF/Yr

22,786 sqft

Medical office space for rent near Greenville Memorial Hospital.

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Medical Office Building in Medical Park

10 Memorial Medical Drive, Greenville, SC 29605

Contact for pricing

7,000 sqft

Medical office building in Memorial Medical Park near I-185, offering space for healthcare practices or related offices.

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Turn-Key ADA Accessible Professional Office

106 MEMORIAL DR, Greer, SC 29650

Contact for pricing

1,442 sqft

Newly remodeled office with reception, three private offices, lounge, kitchen, and 10 on-site parking spaces.

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Prime Medical Office Space

800 Pelham Rd, Greenville, SC

$18 SF/Yr

15,448 sqft

Eastside Greenville location near Prisma and Bon Secours campuses.

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Turn Key Medical Office Space

100 Constantine Wy, Greer, SC

$23 SF/Yr

5,000 sqft

New construction medical office space in close proximity to airport.

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Lower-Level Office Suite with Lab Room

1405 Grove Road, Greenville, SC 29605

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Lower-level suite with private offices, conference room, and lab/work room for medical or professional operations.

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Turnkey Healthcare Suite Available

2709 Pelham Road, Greenville, SC 29615

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Ready-to-occupy medical suite with excellent visibility and accessibility.

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Retail Space in Growing Town

Fountain Inn, SC 29644

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Retail and QSR spaces available near Prisma Health Hospital.

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Medical Office Space Available

300 Regent Park Ct, Greenville, SC 29607

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Office spaces for healthcare providers near I-385 & Butler Rd.

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334,000 SF Office Building For Lease

300 South St, Simpsonville, SC 29681

$19 SF/Yr

334,000 SF Office Building For Lease

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Greer Retail & Restaurant Space

2000 Hwy 101 S, Greer, SC

Contact for pricing

2,400 sqft

Retail, restaurant, and medical office spaces available for lease.

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Greenville Office Space For Rent

127 Halton Village Cir, Greenville, SC

$23 SF/Yr

5,600 sqft

Flexible office space near Patewood Medical Campus available for rent.

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Medical Office Space Near Hospital

1200 W Faris Rd, Greenville, SC 29605

Contact for pricing

4,232 sqft

Stand-alone building ideal for medical use near Greenville Memorial.

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Based on your search, we've compiled 22 Potential Opportunities for your consideration. Besides 18 Active listings in Greenville County, SC, we suggest exploring alternatives. Similar 4 Properties for Sales.

Similar Spaces for Sale in Greenville County, SC

Consider Similar Space for Sale. We found 4 Spaces matching your search parameters.

Downtown Fountain Inn Commercial Space

203 S Weston Street, Fountain Inn, SC 29644

$1,500,000

4,400 sqft 0.59 AC lot

Prime location with potential for various business uses.

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Absolute NNN Dental Office

1173 Ashmore Bridge Rd, Greenville, SC 29605

$4,160,000

4,200 sqft

Newly delivered dental office offered on an Absolute NNN basis with a long-term lease and corporate guarantee.

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Freestanding Office Building For Sale

5 Hawthorne Park Ct, Greenville, SC 29615

$1,650,000

6,046 sqft

Freestanding office building in desirable Eastside office corridor.

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Freestanding Office/Medical Building For Sale

4501 Old Spartanburg Rd, Taylors, SC

$430,000

2,306 sqft 0.16 AC lot

Two-story, 2,306 SF office/medical building in established office park.

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Greenville County, SC Medical Office Space Market Trends and Statistics

Explore Medical Office Space leasing options in Greenville County, SC with 18 listings featured on our commercial real estate exchange. The current inventory includes 107,975 square feet of properties with an estimated lease value of $185.67 SF/Yr.

Estimated lease rates for Medical Office Space in Greenville County, SC begin at $13.95 SF/Yr, with an average of $20.63 SF/Yr and extend to $30 SF/Yr.