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    Greenville County, SC Medical Office Space for Lease

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    11 properties
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    Turn-Key ADA Accessible Professional Office
    Updated: Jun 16
    Turn-Key ADA Accessible Professional Office

    106 Memorial Dr, Greer, SC 29650

    $2,200/Mo
    1,442 sqft 0.32 AC lot
    1,442 SF newly remodeled bungalow‑style professional office on a 0.32‑acre lot
    Reception area plus 200 SF lounge, three private 150 SF offices, and a full kitchen
    Fully ADA‑accessible layout with an exterior ramp
    Private rear lot with 10 dedicated on‑site parking spaces
    Lease: $2,200 per month; Triple Net (NNN); minimum 3‑year term with annual 3% increase
    View details
    Medical Office Space For Lease
    Updated: Jan 27
    Medical Office Space For Lease

    10 Enterprise Blvd., Greenville, SC 29615

    $25 SF/Yr
    45,200 sqft
    Prime Location: One block from Prisma Health Patewood Campus & Bon Secours Francis Eastside.
    Medical/Healthcare Focus: Ideal office space for medical or healthcare practices.
    Flexible Lease Terms: Adaptable lease options to suit tenant needs.
    Available Space: 1,634 - 3,297 SF available, offering options for different sized practices.
    Renovated Common Areas: Updated and well‑maintained shared spaces.
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    Medical Office Space For Lease
    Medical Office Space For Lease

    3535 Pelham Road, Greenville, SC 29615

    $13.95 SF/Yr
    8,000 sqft

    Medical office space for lease in Greenville, South Carolina.

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    Second-Generation Medical Office
    Second-Generation Medical Office

    35 Ray E Talley Ct, Simpsonville, SC 29680

    Contact for pricing
    7,880 sqft

    Located near Fairview Road with convenient access to I-385.

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    Retail or Medical Corner Opportunity
    Retail or Medical Corner Opportunity

    6414 State Park Rd, Travelers Rest, SC 29690

    Contact for pricing
    13,813 sqft

    Hard-corner retail/medical site at a signalized intersection with exposure to multiple major thoroughfares.

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    Medical Office Space with Marquee Signage
    Medical Office Space with Marquee Signage

    800 Pelham Rd, Greenville, SC 29615

    Contact for pricing

    Second-generation medical space with existing clinical lab infrastructure and free surface parking near Prisma and Bon Secours.

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    Greenville Office/Medical Space For Rent
    Greenville Office/Medical Space For Rent

    20 Creekview Ct, Greenville, SC 29615

    Contact for pricing

    Office or medical space available in Greenville, SC.

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    334,000 SF Office Building For Lease
    334,000 SF Office Building For Lease

    300 South St, Simpsonville, SC 29681

    $19 SF/Yr

    334,000 SF Office Building For Lease

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    Eastside Building Near Medical Campuses
    Eastside Building Near Medical Campuses

    800 Pelham Rd, Greenville, SC 29615

    Contact for pricing

    Full building opportunity on the Eastside, near Prisma Health.

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    Turn Key Medical Office Space
    Turn Key Medical Office Space

    100 Constantine Wy, Greer, SC

    Contact for pricing
    5,000 sqft 0.61 AC lot

    New construction medical office space in close proximity to airport.

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    Greenville Office Space For Rent
    Greenville Office Space For Rent

    127 Halton Village Cir, Greenville, SC

    Contact for pricing
    5,600 sqft 0.15 AC lot

    Flexible office space near Patewood Medical Campus available for rent.

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    Based on your search, we've compiled 17 Potential Opportunities for your consideration. Besides 11 Active listings in Greenville County, SC, we suggest exploring alternatives. Similar 6 Properties for Sales.

    Similar Spaces for Sale in Greenville County, SC

    Consider Similar Space for Sale. We found 6 Spaces matching your search parameters.

    Historic Mixed-Use Property with Sunroom
    Historic Mixed-Use Property with Sunroom

    1011 W Poinsett Street, Greer, SC 29650

    $685,000
    3,051 sqft

    Distinctive former doctor’s office with period detailing, a detached workshop garage, and flexibility for office, residential, or event use.

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    Single-Level Brick Medical Office
    Single-Level Brick Medical Office

    203 S Weston Street, Fountain Inn, SC 29644

    $1,500,000
    0.59 AC lot

    C-1 zoning, an included adjacent lot, and a detached brick outbuilding support flexible medical-office use.

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    Medical Office Space with Existing Buildout
    Medical Office Space with Existing Buildout

    717 NE Main St, Simpsonville, SC 29681

    Contact for pricing
    3,000 sqft

    Existing chiropractic-office configuration supports continued professional use or conversion for legal and accounting services.

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    Second-Generation Medical Office
    Second-Generation Medical Office

    35 Ray E Talley Ct, Simpsonville, SC 29680

    Contact for pricing
    7,880 sqft

    Well-maintained medical and office space in Simpsonville’s retail corridor near I-385 access.

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    Medical Office with Basement
    Medical Office with Basement

    202 Memorial Drive, Greer, SC 29650

    Contact for pricing
    1,144 sqft 0.34 AC lot

    The property includes on-site parking and additional basement area for potential office conversion.

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    All-Brick Medical Office Building
    All-Brick Medical Office Building

    3115 Brushy Creek Rd, Greer, SC 29650

    Contact for pricing
    6,244 sqft

    All-brick medical office building in a professional office park with a 10-year leaseback.

    View details

    Greenville County, SC Medical Office Space Market Trends and Statistics

    Explore Medical Office Space leasing options in Greenville County, SC with 11 listings featured on our commercial real estate exchange. The current inventory includes 86,935 square feet of properties with an estimated lease value of $76.26.

    Estimated lease rates for Medical Office Space in Greenville County, SC begin at $13.95 SF/Yr, with an average of $19.06 SF/Yr and extend to $25 SF/Yr.
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    Featured Greenville County Real Estate Agencies

    Realmo connects you with licensed Greenville County CRE brokers providing property specifications, local market pricing, and commercial transaction underwriting support.

    Keller Williams Greenville Upstate
    403 Woods Lake Rd Greenville, SC 29607
    Phone: 18642347500
    www.kwgreenvillesc.com
    BlackStream International Real Estate
    20 Overbrook Court, Suite 400 Greenville, SC 29607
    Phone: 18645531998
    www.blackstreaminternational.com
    Coldwell Banker Caine
    111 Williams Street Greenville, SC 29601
    Phone: 18642502800
    cbcaine.com
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