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    Greenville County, SC Medical Office Space for Lease

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    Greenville, SC Columbia, SC Charleston, SC
    20 results
    Medical Office Space For Lease
    $26 SF/Yr
    45,200 SF
    Medical Office Space For Lease

    10 Enterprise Blvd., Greenville, SC 29615

    Medical office space near Prisma Health Patewood & Bon Secours.
    • Prime Location: One block from Prisma Health Patewood Campus & Bon Secours Francis Eastside.
    • Medical/Healthcare Focus: Ideal office space for medical or healthcare practices.
    • Flexible Lease Terms: Adaptable lease options to suit tenant needs.
    • Available Space: 1,634 - 3,297 SF available, offering options for different sized practices.
    • Renovated Common Areas: Updated and well‑maintained shared spaces.
    Updated: Jan 27
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    Medical Office Space For Lease
    $13 SF/Yr
    8,000 SF
    Medical Office Space For Lease

    3535 Pelham Road, Greenville, SC 29615

    Medical office space for lease in Greenville, South Carolina.
    • Prime location on Pelham Road corridor in Greenville County.
    • Convenient access: Less than a mile to I‑85.
    • Medical office space suitable for various practices.
    • Flexible space: Can be divided to suit tenant needs.
    • Features 9 private offices, 2 conference rooms, lobby, and break room.
    Updated: Sep 25, 2025
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    Turnkey Healthcare Suite Available
    Contact for pricing
    Turnkey Healthcare Suite Available

    Ready-to-occupy medical suite with excellent visibility and accessibility.

    2709 Pelham Road, Greenville, SC 29615

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    Greenville Medical Office Space
    $30 SF/Yr
    2,600 SF
    Greenville Medical Office Space

    Modern medical office space available for lease in Greenville, SC.

    3807 White Horse Rd, Greenville, SC

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    Medical Office Near Greenville Memorial
    $18 SF/Yr
    22,786 SF
    Medical Office Near Greenville Memorial

    Medical office space for rent near Greenville Memorial Hospital.

    8 Memorial Medical Ct, Greenville, SC

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    Medical Office Space For Lease
    $18 SF/Yr
    3,000 SF
    Medical Office Space For Lease

    Medical office space available for lease in Greenville, SC.

    274 B Commonwealth Drive, Greenville, SC 29615

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    Retail/Medical Space in Travelers Rest
    Contact for pricing
    13,813 SF
    Retail/Medical Space in Travelers Rest

    High-visibility retail/medical space in a thriving Upstate community.

    6414 State Park Rd, Travelers Rest, SC 29690

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    Prime Medical Office Space
    $18 SF/Yr
    15,448 SF
    Prime Medical Office Space

    Eastside Greenville location near Prisma and Bon Secours campuses.

    800 Pelham Rd, Greenville, SC

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    Medical Office Space For Rent
    Contact for pricing
    1,336 SF
    Medical Office Space For Rent

    Newly renovated medical office space in Greenville's medical corridor.

    62 Bear Dr, Greenville, SC

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    334,000 SF Office Building For Lease
    $19 SF/Yr
    334,000 SF Office Building For Lease

    334,000 SF Office Building For Lease

    300 South St, Simpsonville, SC 29681

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    Two-Story Office Building Available
    Contact for pricing
    5,500 SF
    Two-Story Office Building Available

    Two-story office building with ample parking and multiple access points.

    501 Roper Mountain Rd, Greenville, SC

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    Piedmont Office/Medical Suite For Rent
    $16 SF/Yr
    2,835 SF
    Piedmont Office/Medical Suite For Rent

    Office/medical suite for lease near Highway 85 and SC-153.

    103-107 Clair Dr, Piedmont, SC

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    Retail Space in Growing Town
    Contact for pricing
    Retail Space in Growing Town

    Retail and QSR spaces available near Prisma Health Hospital.

    Fountain Inn, SC 29644

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    Turn Key Medical Office Space
    $23 SF/Yr
    5,000 SF
    Turn Key Medical Office Space

    New construction medical office space in close proximity to airport.

    100 Constantine Wy, Greer, SC

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    Simpsonville Retail Space For Lease
    Contact for pricing
    7,500 SF
    Simpsonville Retail Space For Lease

    Up to 7,500 SF retail space in Simpsonville, SC.

    721 SE Main St, Simpsonville, SC 29681

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    Medical Office Space Available
    Contact for pricing
    Medical Office Space Available

    Office spaces for healthcare providers near I-385 & Butler Rd.

    300 Regent Park Ct, Greenville, SC 29607

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    Greer Retail & Restaurant Space
    Contact for pricing
    2,400 SF
    Greer Retail & Restaurant Space

    Retail, restaurant, and medical office spaces available for lease.

    2000 Hwy 101 S, Greer, SC

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    Greenville Office Space For Rent
    $23 SF/Yr
    5,600 SF
    Greenville Office Space For Rent

    Flexible office space near Patewood Medical Campus available for rent.

    127 Halton Village Cir, Greenville, SC

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    Land Available For Development
    Contact for pricing
    Land Available For Development

    Land available for ground lease or build to suit.

    13435 E Wade Hampton Blvd, Greer, SC 29651

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    Medical Office Space Near Hospital
    Contact for pricing
    4,232 SF
    Medical Office Space Near Hospital

    Stand-alone building ideal for medical use near Greenville Memorial.

    1200 W Faris Rd, Greenville, SC 29605

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    Based on your search, we've compiled 26 Potential Opportunities for your consideration. Besides 20 Active listings in Greenville County, SC, we suggest exploring alternatives. Similar 6 Properties for Sales.

    Similar Spaces for Sale in Greenville County, SC

    Consider Similar Space for Sale. We found 6 Spaces matching your search parameters.

    Downtown Fountain Inn Commercial Space
    $1,500,000
    4,400 SF
    Downtown Fountain Inn Commercial Space

    Prime location with potential for various business uses.

    203 S Weston Street, Fountain Inn, SC 29644

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    Medical Office Building For Sale
    $2,395,000
    7,397 SF
    Medical Office Building For Sale

    Two-story, ±7,397 SF medical office building suited for owner-occupant.

    300 Regent Park Ct, Greenville, SC

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    Medical Office Near Unity Park
    Contact for pricing
    4,076 SF
    Medical Office Near Unity Park

    Medical office space for sale near Unity Park.

    20 Mayfield Street, Greenville, SC 29601

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    Remodeled Office Space Near Downtown
    $475,000
    1,442 SF
    Remodeled Office Space Near Downtown

    Charming, remodeled office space suitable for medical or professional services.

    106 Memorial Dr, Greer, SC 29650

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    Greenville County, SC Medical Office Space Leasing Opportunities Market Analysis

    Explore Medical Office Space leasing options in Greenville County, SC with 20 listings featured on our commercial real estate exchange. The current inventory includes 110,469 square feet of properties with an estimated lease value of $186 SF/Yr.

    Estimated lease rates for Medical Office Space in Greenville County, SC begin at $13 SF/Yr, with an average of $20 SF/Yr and extend to $30 SF/Yr.
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