South Carolina
    For Sale
    • For Sale
    • For Lease
    • Recently Sold
    • Property Lookup
    • Brokers
    Property Types
    • Retail
    • Office
    • Residential Income
    • Restaurants
    • Industrial
    • Mixed-Use
    • Hospitality
    • Health Care
    • Sports & Entertainment
    • Land
    • Agricultural
    • Specialty
    Price
    Price
    $
    $

    South Carolina Commercial Real Estate for Sale

    Notify Me
    List
    Map
    Columbia, SC Greenville, SC Spartanburg, SC
    5,296 listings
    Medical Office Building with Exam Rooms
    $1,899,000
    3,988 SF
    Medical Office Building with Exam Rooms

    116 Professional Park Dr., Conway, SC 29526

    Brand-new medical office with 9 exam rooms, dedicated HVAC, and ample parking for patient-centered care.
    • Brand‑new brick construction medical office space available at Singleton Ridge Professional Business Park
    • Layout includes 9 exam rooms, 3 private offices, and a reception area and lobby
    • Additional rooms include a medical technician workspace, laboratory room, and computer room with dedicated HVAC
    • 3 bathrooms and on‑site parking for 25 vehicles
    • Located on Singleton Ridge Road next to Conway Medical Center, Coastal Carolina University, and Horry‑Georgetown Technical College
    Updated: Jun 5
    View details
    Automotive Service and Showroom Building
    $795,000
    8,816 SF
    Automotive Service and Showroom Building

    849 Highway 1 S, Lugoff, SC 29078

    Metal building with showroom, paved parking, and eight service bays plus updated HVAC.
    • Metal building built in 1980 with central heating and central air conditioning
    • Front includes a large showroom and paved parking, plus several office spaces
    • Back area features 8 service bays for automotive use
    • Includes two car lifts: a 4‑post lift and a 2‑post lift, plus parts room, tool room, and office
    • 3 bathrooms and additional storage areas
    Updated: Jun 6
    View details
    Adaptable Commercial Property on Highway
    $925,000
    8,700 SF
    Adaptable Commercial Property on Highway

    Warehouse and office buildings with high traffic frontage on Highway.

    6114 HWY 76, Pendleton, SC 29670

    View details
    Multi-Building Flex and Office Property
    $1,100,000
    3,970 SF
    Multi-Building Flex and Office Property

    Two income-producing buildings with office, warehouse, fencing, and multiple driveways for flexible owner or tenant use.

    4251 Whiskey Road, Aiken, SC 29803

    View details
    Turnkey Restaurant with Commercial Kitchen
    $549,900
    3,200 SF
    Turnkey Restaurant with Commercial Kitchen

    Fully equipped dine-in restaurant with a remodeled dining area, spacious kitchen, and seating for 50+.

    418 W Mcintyre St, Mullins, SC 29574

    View details
    Freestanding Commercial Building on Wade Hampton
    $1,600,000
    13,800 SF
    Freestanding Commercial Building on Wade Hampton

    Adaptable commercial building with multi-occupancy flexibility and high visibility.

    14629 E Wade Hampton Boulevard, Greer, SC 29651

    View details
    Conway Convenience Store with Expansion Potential
    $2,500,000
    6,215 SF
    Conway Convenience Store with Expansion Potential

    Established convenience store on 1.25 acres with growth opportunities.

    965 Bucksport Rd., Conway, SC 29527

    View details
    Turn-Key Dental Office in Aiken
    $1,200,000
    4,044 SF
    Turn-Key Dental Office in Aiken

    Well-appointed dental office near downtown and I-20.

    1466 Columbia Highway, Aiken, SC 29801

    View details
    Turn-Key Dental Office in Aiken
    $1,200,000
    4,044 SF
    Turn-Key Dental Office in Aiken

    Well-appointed dental office with prime location and included equipment.

    1466 Columbia Highway N, Aiken, SC 29801

    View details
    Two-Story Office Building with Parking
    $799,000
    7,759 SF
    Two-Story Office Building with Parking

    Two-story office building with reception, multiple private offices, conference space, and wraparound parking.

    311 W Home Ave, Hartsville, SC 29550

    View details
    Downtown Fountain Inn Commercial Space
    $1,500,000
    4,400 SF
    Downtown Fountain Inn Commercial Space

    Prime location with potential for various business uses.

    203 S Weston Street, Fountain Inn, SC 29644

    View details
    Elloree Commercial Portfolio For Sale
    $1,475,000
    13,900 SF
    Elloree Commercial Portfolio For Sale

    Five buildings in Elloree, SC, suitable for retail, office, mixed-use.

    2725 Cleveland Street, Elloree, SC 29047

    View details
    Redevelopment Opportunity in Beaufort, SC
    $2,495,000
    6,500 SF
    Redevelopment Opportunity in Beaufort, SC

    Rare mixed-use redevelopment site with high visibility and trail access.

    12 Neil Road, Beaufort, SC 29906

    View details
    Versatile Commercial Property, Cleveland SC
    $650,000
    3,355 SF
    Versatile Commercial Property, Cleveland SC

    Two well-maintained buildings on 1.89 acres with mountain views.

    4033 Geer Highway, Cleveland, SC 29635

    View details
    Two Retail Buildings on Large Lot
    $969,000
    8,420 SF
    Two Retail Buildings on Large Lot

    Two retail buildings on a 2.32-acre lot zoned GC, offering flexibility for multiple business models at one address.

    1219 NE ByPass 72, Greenwood, SC 29649

    View details
    Mixed-Use Site in Beaufort, SC
    $2,250,000
    6,273 SF
    Mixed-Use Site in Beaufort, SC

    Mixed-use site with redevelopment potential in a promising corridor.

    8 Neil Road, Beaufort, SC 29906

    View details
    Highway Frontage Commercial Site
    $799,000
    7,300 SF
    Highway Frontage Commercial Site

    One-acre commercial site with 7,300 SF building and ample parking.

    3520 Trask Parkway, Beaufort, SC 29906

    View details
    Freestanding Commercial Site in Aiken
    $850,000
    9,012 SF
    Freestanding Commercial Site in Aiken

    Well-located commercial property with redevelopment potential in Aiken, SC.

    1110 Richland Avenue E, Aiken, SC 29801

    View details
    Aiken Commercial Office Building
    $550,000
    2,595 SF
    Aiken Commercial Office Building

    Well-positioned office building in a convenient, accessible Aiken location.

    160 Waterloo Street SW, Aiken, SC 29801

    View details
    Versatile Commercial Building, Spartanburg, SC
    $319,900
    3,445 SF
    Versatile Commercial Building, Spartanburg, SC

    Adaptable commercial building suitable for office, retail, or automotive uses.

    250 Cedar Springs Avenue, Spartanburg, SC 29302

    View details
    Renovated Office Building in Greer
    $1,200,000
    10,000 SF
    Renovated Office Building in Greer

    Updated office building with multiple suites and ample parking.

    554 Memorial Drive Extension, Greer, SC 29651

    View details
    Charming Cleveland Cafe and Store
    $650,000
    2,930 SF
    Charming Cleveland Cafe and Store

    Turnkey cafe and general store in scenic Cleveland, SC.

    4000 Geer Highway, Cleveland, SC 29635

    View details
    Versatile Commercial Property on Edmund Highway
    $799,000
    4,090 SF
    Versatile Commercial Property on Edmund Highway

    Commercial property with restaurant and warehouse in Lexington, SC.

    6196 Edmund Highway, Lexington, SC 29073

    View details
    Greenville Commercial Property with Buildings
    $1,800,000
    2,400 SF
    Greenville Commercial Property with Buildings

    Prime commercial property with existing buildings and high visibility.

    6225 White Horse Rd, Greenville, SC 29611

    View details

    South Carolina Commercial Real Estate Investment Opportunities Market Analysis

    Explore 5000+ commercial real estate for sale in South Carolina, showcased through 5000+ active listings on our real estate platform. These investment opportunities span a total of 66,859,402 square feet of properties for sale, with an estimated market value of $2,749,527,360.

    Sale prices for business properties in South Carolina start at $39,000, averaging $1,640,529, and reaching up to $64,403,460 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

    List
    Map