South Carolina Commercial Real Estate for Sale

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Columbia, SC Greenville, SC Spartanburg, SC Myrtle Beach, SC Hilton Head Island, SC Aiken, SC Anderson, SC Charleston, SC

5,586 properties

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Updated: Aug 12

Single-Story Office Building

2185 N Fraser St., Georgetown, SC 29440

$800,000

4,760 sqft 0.99 AC lot

4,760‑square‑foot vacant, single‑story brick commercial building
NC zoning for Neighborhood Commercial development
Existing layout includes reception, multiple rooms, private offices, kitchen, storage, and restrooms
Most recently operated as a daycare facility
Rear porch, accessibility ramp, fire alarm, and security system

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Updated: Sep 3

Two-Building Office Property

1511 Bush River Road, Columbia, SC 29210

$500,000

5,784 sqft 0.55 AC lot

Two separate office buildings on a 0.55‑acre site
5,784 square feet of listed building area
One building is tenant‑occupied; the second is vacant
Vacant building contains two office suites
Reception areas, private offices, conference room, restrooms, and kitchenette

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Automotive Service Shop with Office

1449 Union Street, Spartanburg, SC 29302

$2,499,900

5,619 sqft 0.77 AC lot

Functional automotive facility with service lifts, customer office space, central air, and public water.

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High-Capacity Restaurant Property

801 Hwy 17 S #8th Ave S, North Myrtle B, 8th Ave S, North Myrtle Beach, SC 29582

$2,500,000

7,254 sqft 1.75 AC lot

Equipped restaurant with expansive dining, bar, commercial kitchen, patio, and substantial on-site parking.

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Automotive Salvage Shop and Yard

314 S Hwy 221, Greenwood, SC 29646

$1,599,000

12,000 sqft 34.88 AC lot

Operating salvage facilities include processing shops, an office, on-site housing, and a pond across a large acreage tract.

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Automotive Service Property

5229 Augusta Highway, Leesville, SC 29070

$650,000

4,500 sqft 2.96 AC lot

Flexible improvements combine vehicle-service capability, covered storage, offices, and residentially permitted space.

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Flex Property With Garage

118 Rainbow Lake Road, Boiling Springs, SC 29316

$1,250,000

1,440 sqft 0.76 AC lot

Office and automotive improvements support continued car-lot operations, service use, or a combination of commercial functions.

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Single-Tenant Government-Leased Office Building

531 Robertson Blvd, Walterboro, SC 29488

$1,865,000

7,968 sqft 1.23 AC lot

Single-story office asset occupied by a federal government tenant under an existing lease.

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Flexible Multi-Suite Flex Space

313 Commerce Dr., Pawleys Island, SC 29585

$1,200,000

8,812 sqft 1.20 AC lot

PD-zoned commercial building with four suites combining office, medical, warehouse, and mezzanine space.

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Mixed-Use Property with Storage

4939 Hwy 321, Gaston, SC 29053

$1,395,000

10,775 sqft 1.48 AC lot

Multiple commercial buildings provide shop space, storage units, and overhead bay doors.

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Professional Office Building with Dual Entrances

1530 Highmarket St., Georgetown, SC 29440

$750,000

7,205 sqft

Flexible professional workspace with private offices, conference facilities, updated systems, and infrastructure for connected business operations.

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Motel Along Highway Corridor

7448 HWY 34 E, Ridgeway, SC 29130

$900,000

5,103 sqft 2.17 AC lot

Existing lodging property with B2 zoning, wall-unit cooling, and shingle roofing.

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Medical Office Building with Exam Rooms

1466 Columbia Highway N, Aiken, SC 29801

$1,200,000

4,044 sqft 0.82 AC lot

Nine plumbed exam rooms support a clinical layout with reception, practitioner offices, and a private executive suite.

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Renovated Two-Story Office Building

332 Edgefield Rd, North Augusta, SC 29841

$1,200,000

6,380 sqft 0.81 AC lot

Recently updated professional offices with multiple workrooms, conference and training areas, parking, and fiber-ready connectivity.

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Medical Office with Dental Buildout

1466 Columbia Highway, Aiken, SC 29801

$1,200,000

4,044 sqft 0.82 AC lot

Brick facility includes plumbed exam rooms, executive offices, reception, lab, kitchen, and multiple restrooms.

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Auto Shop with Vehicle Lifts

176 Bomar Street, Inman, SC 29349

$649,900

2,400 sqft 1.66 AC lot

Corner-site facility with direct Highway 292 access, a dedicated office, multiple restrooms, and on-site parking.

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Flex Building With Drive-In Doors

1007 South Murray Avenue, Anderson, SC 29624

$525,000

9,780 sqft 0.85 AC lot

General Commercial zoning combines renovated office/showroom space with warehouse functionality.

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Purpose-Built Assisted Living Facility

2317 Prince St., Georgetown, SC 29440

$899,000

7,206 sqft 0.50 AC lot

Operating personal care home with residential accommodations, communal areas, and healthcare-supporting building systems.

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Office Building on Acreage

525 N. Lafayette, Sumter, SC 29150

$795,000

7,490 sqft 3.69 AC lot

Existing commercial improvements with General Commercial and R6 zoning support multiple potential use configurations.

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Showroom Property with Service Bays

3478 Alex Harvin Highway, Manning, SC 29102

$993,000

8,280 sqft 3.20 AC lot

Fenced commercial site with display space, mechanic bays, and access to US-301 near I-95.

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Two-Story Office Building with Elevator

1044 William Hilton Pkwy, Hilton Head Island, SC 29928

$2,200,000

10,017 sqft

Flexible layout with private offices, training areas, storage, and kitchenette or breakroom spaces.

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Leased 4-Unit Mixed-Use Building

2614 E Highway 76, Marion, SC 29571

$585,000

7,200 sqft 0.85 AC lot

Fully occupied commercial space combines office and retail uses with highway access and rear entry.

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Office-Showroom Warehouse Building

29 Kitties Landing Road, Bluffton, SC 29910

$2,475,000

10,000 sqft 1.00 AC lot

Metal-frame office, showroom, and warehouse building with four roll-up doors and full HVAC on about one acre.

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Flex Space with Multiple Sections

4886 Sunset Boulevard, Lexington, SC 29072

$2,100,000

12,000 sqft 1.83 AC lot

Two-building commercial property with leased sections, vacant industrial space, and restroom facilities throughout.

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South Carolina Commercial Real Estate Market Trends and Statistics

Explore 5000+ commercial real estate for sale in South Carolina, showcased through 5000+ active listings on our real estate platform. These investment opportunities span a total of 172,923,375 square feet of properties for sale, with an estimated market value of $3,677,240,108.

Sale prices for business properties in South Carolina start at $31,500, averaging $982,693, and reaching up to $34,900,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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