South Carolina Commercial real estate for sale

Updated: Oct 15

Flex Property with Showroom

1885 Joe S Jeffords Highway, Orangeburg, SC 29115

$575,000

9,600 sqft 2.40 AC lot

9,600‑square‑foot building on 2.4 acres
Three sections include showroom, offices, and warehouse
Warehouse fitted with a 3‑ton crane
Signalized junction of three highways; approximately 30,000 vehicles pass daily
1885 Joe S Jeffords Highway, Orangeburg, SC 29115

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Updated: Oct 13

Corner Mixed-Use Property

900 Main Street S, New Ellenton, SC 29809

$750,000

10,000 sqft 4.51 AC lot

4.51‑acre corner parcel at S Main Street (SC‑19) and Williston Road (US‑278)
Restaurant space of +/-5,320 SF with commercial kitchen, two built‑in bars, dining and event areas
Warehouse of +/-2,080 SF with about 14' eaves and two 10' roll‑up doors
Office/apartment space of +/-1,190 SF and standalone garage apartment of +/-961 SF
Zoned UD (Urban Development) for general and neighborhood commercial, residential, and light manufacturing uses

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Equipped Restaurant with Loft Apartment

7000 Woodside Executive Court, Aiken, SC 29803

$1,500,000

4,100 sqft 1.96 AC lot

Restaurant property with event-use flexibility, public utilities, and an upstairs loft apartment.

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High-Capacity Restaurant Property

801 Hwy 17 S #8th Ave S, North Myrtle B, 8th Ave S, North Myrtle Beach, SC 29582

$2,500,000

7,254 sqft 1.75 AC lot

Equipped restaurant with expansive dining, bar, commercial kitchen, patio, and substantial on-site parking.

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Freestanding Storefront with Two Suites

508 N Kings Hwy., Myrtle Beach, SC 29577

$1,695,000

5,400 sqft 0.46 AC lot

MU-H zoning, two curb cuts, and roadside signage support flexible retail occupancy.

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Two-Building Office Property

1511 Bush River Road, Columbia, SC 29210

$500,000

5,784 sqft 0.55 AC lot

Office property with tenant-occupied and vacant space, private offices, reception areas, conference facilities, and on-site parking.

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Historic Event Venue with Commercial Kitchen

514 Rutledge Street, Camden, SC 29020

$995,000

6,117 sqft

Renovated downtown facility with dining, event, catering, and covered outdoor areas.

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Flex Space with Expansion Capacity

50 Capital Drive, Hilton Head Island, SC 29926

$1,599,000

4,000 sqft 1.50 AC lot

Light Industrial property combining office, warehouse, storage units, and additional buildable capacity.

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Single-Story Office Building

2185 N Fraser St., Georgetown, SC 29440

$800,000

4,760 sqft 0.99 AC lot

Vacant brick building with reception, offices, multiple program rooms, kitchen, storage, and public and private restrooms.

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Mixed-Use Property with Storage

4939 Hwy 321, Gaston, SC 29053

$1,150,000

10,775 sqft 1.48 AC lot

Multiple commercial buildings provide shop space, storage units, and overhead bay doors.

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Remodeled Freestanding Retail Building

508 North Kings Highway, Myrtle Beach, SC 29577

$1,695,000

5,400 sqft 0.46 AC lot

Two separately configured suites can operate independently or connect as a larger storefront.

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Brick Church with Stained Glass

1408 Third Street, Newberry, SC 29108

$595,000

11,026 sqft 1.88 AC lot

Interior spaces include a sanctuary, classrooms, offices, a kitchen, restrooms, and multipurpose areas.

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Freestanding Office Building

403 North Lake Drive, Lexington, SC 29072

$645,000

2,872 sqft 0.42 AC lot

Professional office property with a long-term tenant and central air conditioning.

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Single-Tenant Government-Leased Office Building

531 Robertson Blvd, Walterboro, SC 29488

$1,865,000

7,968 sqft 1.23 AC lot

Single-story office asset occupied by a federal government tenant under an existing lease.

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Showroom Property with Service Bays

3478 Alex Harvin Highway, Manning, SC 29102

$992,000

8,280 sqft 3.20 AC lot

Fenced commercial site with display space, mechanic bays, and access to US-301 near I-95.

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Medical Office with Separate Patient Routes

600 Singleton Ridge Rd., Conway, SC 29526

$1,250,000

3,114 sqft 0.53 AC lot

The clinic layout provides distinct paths for patients entering and leaving the building.

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Mixed-Use Property with On-Site Parking

906 Augusta Street, Greenville, SC 29605

$1,395,000

4,000 sqft

Four exterior entrances provide access to distinct areas of the building.

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Two-Story Office Building

311 W Home Ave, Hartsville, SC 29550

$799,000

7,759 sqft 0.82 AC lot

Flexible professional layout with numerous private rooms, executive offices, conference space, and wraparound parking.

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Medical Office Property with ADU

1586 Skylyn Drive, Spartanburg, SC 29307

$535,000

2,466 sqft 0.59 AC lot

Two separate buildings offer adaptable interior rooms and direct entry to the Mary Black Rail Trail.

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Mixed-Use Townhome with Commercial Space

2798 Howard Ave., Myrtle Beach, SC 29577

$639,000

2,018 sqft 0.03 AC lot

Street-facing ground-floor flex space sits beneath a three-bedroom residence with a fenced backyard.

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Two-Suite Office Condominium

137-139 Commons Way, Greenville, SC 29611

$575,000

4,200 sqft

Both units feature private offices, reception and conference areas, break rooms, and flexible second-floor workspace.

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Flex Property With Garage

118 Rainbow Lake Road, Boiling Springs, SC 29316

$1,250,000

1,440 sqft 0.76 AC lot

Office and automotive improvements support continued car-lot operations, service use, or a combination of commercial functions.

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Medical Office with 9 Exam Rooms

1466 Columbia Hwy, Aiken, SC 29801

$1,200,000

4,044 sqft

Brick healthcare facility with a covered entry, executive suite, lab, and included FF&E.

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Fuel Station with Convenience Store

1135 Durham Rd, Blackstock, SC 29014

$699,900

3,239 sqft 1.19 AC lot

Operating commercial property with fuel infrastructure, deli equipment, prepared-food capability, and multiple product offerings.

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South Carolina Commercial Real Estate Market Trends and Statistics

Explore 5000+ commercial real estate for sale in South Carolina, showcased through 5000+ active listings on our real estate platform. These investment opportunities span a total of 170,498,143 square feet of properties for sale, with an estimated market value of $3,940,916,450.

Sale prices for business properties in South Carolina start at $30,000, averaging $996,943, and reaching up to $29,900,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.