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    Lancaster County, SC Office Spaces for Lease

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    Greenville, SC Columbia, SC Charleston, SC
    6 results
    Main Street Commercial Space Available
    $5,000/Mo
    Main Street Commercial Space Available

    120 S Main St, Lancaster, SC 29720

    Versatile commercial space in downtown Lancaster with high visibility.
    • Prime location in downtown Lancaster
    • High visibility and foot traffic
    • Versatile layout for various commercial ventures
    • 100% air conditioned showroom warehouse space
    • Excellent signage opportunities
    Updated: Mar 6
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    Retail, Office, Special Purpose
    Contact for pricing
    3,397 SF
    Retail, Office, Special Purpose

    114 E Gay St, Lancaster, SC 29720

    Retail space · 3,397 SF
    • Located in Downtown Lancaster, a high‑growth area within the Charlotte metro region.
    • Flexible space: Can be leased as a full ±3,397 SF floor or subdivided into suites (±1,520 to ±1,840 SF).
    • Landlord will consider select mechanical and electrical upfits.
    • Suitable for retail or office users.
    • Significant population growth in Lancaster County (12.7% from 2020‑2023).
    Updated: Aug 2, 2024
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    Class A Office Space Available
    Contact for pricing
    30,978 SF
    Class A Office Space Available

    120,000 SF Class A office space for rent.

    1000 Corporate Center Way, Indian Land, SC

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    New Class A Medical/Office Development
    Contact for pricing
    60,000 SF
    New Class A Medical/Office Development

    New Class A medical/office development in Edgewater Corporate Park.

    00 Edgewater Pkwy, Indian Land, SC 29707

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    New Class A Medical/Office Development
    Contact for pricing
    60,000 SF
    New Class A Medical/Office Development

    New Class A medical/office development in Edgewater Corporate Park.

    Edgewater Pkwy, Indian Land, SC 29707

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    Edgewater Medical/Office Building III
    Contact for pricing
    15,000 SF
    Edgewater Medical/Office Building III

    Medical and office spaces available for lease in Indian Land.

    Edgewater Pkwy, Indian Land, SC 29707

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    Based on your search, we've compiled 21 Potential Opportunities for your consideration. Besides 6 Active listings in Lancaster County, SC, we suggest exploring alternatives. Similar 11 Properties for Sales.

    Similar Spaces for Sale in Lancaster County, SC

    Consider Similar Space for Sale. We found 11 Spaces matching your search parameters.

    Kershaw Office Building on Large Lot
    $200,000
    1,100 SF
    Kershaw Office Building on Large Lot

    Office building on 1.76 acres in Kershaw, South Carolina.

    104 S Ashe Street, Kershaw, SC 29067

    View details
    Lancaster Commercial Building For Sale
    $139,999
    0.12 Acres
    Lancaster Commercial Building For Sale

    Commercial building in growing area with business or investment potential.

    401 E Gay Street, Lancaster, SC 29720

    View details
    Two Professional Buildings Near MUSC
    $975,000
    0.82 Acres
    Two Professional Buildings Near MUSC

    Two professional office buildings near MUSC in Lancaster, South Carolina.

    1201 Colonial Commons Court, Lancaster, SC 29720

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    Versatile Commercial Building in Lancaster
    $349,000
    Versatile Commercial Building in Lancaster

    Two-story commercial building with offices in downtown Lancaster, SC.

    302 N White St, Lancaster, SC 29720

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    Medical Office Buildings Near MUSC
    $975,000
    Medical Office Buildings Near MUSC

    Two professional buildings suitable for medical or office use.

    1201 Colonial Commons Ct, Lancaster, SC 29720

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    Former Medical Office Space
    $150,000
    3,550 SF
    Former Medical Office Space

    3,350 SF medical office with 11 parking spaces.

    110 South Cleveland Street, Kershaw, SC 29067

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    Versatile Flex, Office, Warehouse Space
    $11,615,750
    92,926 SF
    Versatile Flex, Office, Warehouse Space

    92,926 SF flex, office, and warehouse space for sale.

    11632 Harrisburg Rd, Indian Land, SC

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    Prime Retail and Commercial Development
    $900,000
    Prime Retail and Commercial Development

    Retail and commercial development in a high-traffic area.

    9425 Charlotte Highway, Indian Land, SC 29707

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    Commercial Property for Sale
    $149,900
    1,248 SF
    Commercial Property for Sale

    Commercial property suitable for office, retail, or salon.

    2836 Lynwood Drive, Lancaster, SC 29720

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    Lancaster Medical/Office Space Available
    $875,000
    6,900 SF
    Lancaster Medical/Office Space Available

    Versatile space near MUSC Health Lancaster Medical Center.

    980 N Woodland Dr, Lancaster, SC

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    12.4 Acres Assemblage in Indian Land
    Contact for pricing
    12.40 Acres
    12.4 Acres Assemblage in Indian Land

    12.4 acres in Indian Land, South Carolina for sale.

    Charlotte Hwy, Indian Land, SC 29707

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    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Land Lease Opportunity in Waxhaw
    $8,000/Mo
    Land Lease Opportunity in Waxhaw

    5.341-acre commercial land for lease in a high-growth area.

    5325 Waxhaw Marvin Road, Waxhaw, NC 28173

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    Prime Development Opportunity in Greenville
    Contact for pricing
    Prime Development Opportunity in Greenville

    1.27 acre interstate-visible land for ground lease or build-to-suit.

    39 Airpark Ct, Greenville, SC 29607

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    Commercial Land in Murrells Inlet
    $2,500/Mo
    Commercial Land in Murrells Inlet

    1.49 acres of commercial land for lease.

    Inlet Square Dr., Murrells Inlet, SC 29576

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    Prime Commercial Land For Lease
    $285,000 SF/Yr
    Prime Commercial Land For Lease

    3 acres of B-3 zoned land with city amenities.

    220 Silver Lake Road, Church Hill, TN 37642

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    Lancaster County, SC Office Spaces Leasing Opportunities Market Analysis

    Explore Office Spaces leasing options in Lancaster County, SC with 6 listings featured on our commercial real estate exchange. The current inventory includes 169,375 square feet of properties with an estimated lease value of $0.00 SF/Yr.

    Estimated lease rates for Office Spaces in Lancaster County, SC begin at $0.00 SF/Yr, with an average of $0.00 SF/Yr and extend to $0.00 SF/Yr.
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