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Lancaster County, SC Office Spaces for Lease

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7 properties
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Main Street Commercial Space Available
Updated: Mar 6
Main Street Commercial Space Available

120 S Main St, Lancaster, SC 29720

$5,000/Mo
Prime location in downtown Lancaster
High visibility and foot traffic
Versatile layout for various commercial ventures
100% air conditioned showroom warehouse space
Excellent signage opportunities
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Retail, Office, Special Purpose
Updated: Aug 2, 2024
Retail, Office, Special Purpose

114 E Gay St, Lancaster, SC 29720

Contact for pricing
3,397 sqft
Located in Downtown Lancaster, a high‑growth area within the Charlotte metro region.
Flexible space: Can be leased as a full ±3,397 SF floor or subdivided into suites (±1,520 to ±1,840 SF).
Landlord will consider select mechanical and electrical upfits.
Suitable for retail or office users.
Significant population growth in Lancaster County (12.7% from 2020‑2023).
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Class A Office Sublease Opportunity
Class A Office Sublease Opportunity

8106 Calvin Hall Rd, Indian Land, SC 29707

Contact for pricing
151,500 sqft

Sublease opportunity in desirable corporate office location in Indian Land.

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Class A Office Space Available
Class A Office Space Available

1000 Corporate Center Way, Indian Land, SC

Contact for pricing
30,978 sqft

120,000 SF Class A office space for rent.

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New Class A Medical/Office Development
New Class A Medical/Office Development

00 Edgewater Pkwy, Indian Land, SC 29707

Contact for pricing
60,000 sqft

New Class A medical/office development in Edgewater Corporate Park.

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Edgewater Medical/Office Building III
Edgewater Medical/Office Building III

Edgewater Pkwy, Indian Land, SC 29707

Contact for pricing
15,000 sqft

Medical and office spaces available for lease in Indian Land.

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New Class A Medical/Office Development
New Class A Medical/Office Development

Edgewater Pkwy, Indian Land, SC 29707

Contact for pricing
60,000 sqft

New Class A medical/office development in Edgewater Corporate Park.

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Based on your search, we've compiled 22 Potential Opportunities for your consideration. Besides 7 Active listings in Lancaster County, SC, we suggest exploring alternatives. Similar 11 Properties for Sales.

Similar Spaces for Sale in Lancaster County, SC

Consider Similar Space for Sale. We found 11 Spaces matching your search parameters.

Kershaw Office Building on Large Lot
Kershaw Office Building on Large Lot

104 S Ashe Street, Kershaw, SC 29067

$200,000
1,100 sqft 1.76 AC lot

Office building on 1.76 acres in Kershaw, South Carolina.

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Historic Mixed-Use Retail/Office Buildings
Historic Mixed-Use Retail/Office Buildings

209-227 S. Main Street, Lancaster, SC 29720

$575,000
29,151 sqft

Vacant 1930s buildings offer retail or office space and renovation opportunity in downtown Lancaster, South Carolina.

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Downtown Mixed-Use Redevelopment Property
Downtown Mixed-Use Redevelopment Property

210 S. White Street, Lancaster, SC 29720

$760,000
22,251 sqft

Vacant 1930s retail/office buildings in downtown Lancaster offer a renovation-ready canvas for mixed-use redevelopment.

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1930s Retail/Office Building Portfolio
1930s Retail/Office Building Portfolio

116 Arch Street, Lancaster, SC 29720

$575,000
29,444 sqft

Vacant, renovation-needed buildings offering flexible retail or office space in downtown Lancaster with convenient highway access.

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Downtown Mixed-Use Building for Renovation
Downtown Mixed-Use Building for Renovation

229 S. Main Street, Lancaster, SC 29720

$275,000
15,266 sqft

Vacant 1930s mixed-use property in downtown Lancaster, built for retail or office re-activation with renovation underway.

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Former Medical Office Space
Former Medical Office Space

110 South Cleveland Street, Kershaw, SC 29067

$150,000
3,550 sqft

3,350 SF medical office with 11 parking spaces.

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Two-Building Professional Office Property
Two-Building Professional Office Property

1201 Colonial Commons Court, Lancaster, SC 29720

$975,000
0.82 AC lot

Two professional buildings offer medical-office rooming and upper-level work areas on a single property.

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Medical Office Buildings Near MUSC
Medical Office Buildings Near MUSC

1201 Colonial Commons Ct, Lancaster, SC 29720

$975,000

Two professional buildings suitable for medical or office use.

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Versatile Commercial Building in Lancaster
Versatile Commercial Building in Lancaster

302 N White St, Lancaster, SC 29720

$325,000

Two-story commercial building with offices in downtown Lancaster, SC.

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Versatile Flex, Office, Warehouse Space
Versatile Flex, Office, Warehouse Space

11632 Harrisburg Rd, Indian Land, SC

$11,615,750
92,926 sqft 31.89 AC lot

92,926 SF flex, office, and warehouse space for sale.

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Prime Retail and Commercial Development
Prime Retail and Commercial Development

9425 Charlotte Highway, Indian Land, SC 29707

$900,000

Retail and commercial development in a high-traffic area.

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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Land Lease Opportunity in Waxhaw
Land Lease Opportunity in Waxhaw

5325 Waxhaw Marvin Road, Waxhaw, NC 28173

$8,000/Mo

5.341-acre commercial land for lease in a high-growth area.

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Prime Development Opportunity in Greenville
Prime Development Opportunity in Greenville

39 Airpark Ct, Greenville, SC 29607

Contact for pricing

1.27 acre interstate-visible land for ground lease or build-to-suit.

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Prime Commercial Land For Lease
Prime Commercial Land For Lease

220 Silver Lake Road, Church Hill, TN 37642

$285,000/Mo

3 acres of B-3 zoned land with city amenities.

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Commercial Land Near Interstate 40
Commercial Land Near Interstate 40

310 Goose Creek Road, Dandridge, TN 37725

$499,900/Mo
1,860 sqft

3.96 acres with high visibility near Interstate 40.

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Lancaster County, SC Office Spaces Market Trends and Statistics

Explore Office Spaces leasing options in Lancaster County, SC with 7 listings featured on our commercial real estate exchange. The current inventory includes 320,875 square feet of properties with an estimated lease value of $0.00 SF/Yr.

Estimated lease rates for Office Spaces in Lancaster County, SC begin at $0.00 SF/Yr, with an average of $0.00 SF/Yr and extend to $0.00 SF/Yr.
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