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    Anderson County, SC Office Properties & Spaces for Lease

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    Columbia, SC Greenville, SC Charleston, SC
    20 results
    Class A Office Space
    $3,400 /Mo

    Class A Office Space

    2315 N Main Street, Anderson, SC 29621

    Professional office suite for rent in Anderson, SC.

    • Prime Main Street location ideal for high‑visibility professional business.
    • Class A office building with included maintenance, electric, and water.
    • Versatile 2,800 sq ft suite suitable for medical or professional use.
    • Functional layout with five private offices, open floor plan, two restrooms, and a kitchen area.
    • Includes a welcoming reception area and large parking space.
    Updated: Nov 13, 2025
    View details
    Flex Building with Office, Warehouse
    $4,000 /Mo
    3,200 SF

    Flex Building with Office, Warehouse

    109 Old Denver Road, Anderson, SC 29625

    Flex building with office and warehouse space for lease.

    • +/- 3200 SF flex building with both office and warehouse space.
    • Convenient location near I‑85, Clemson Blvd & Hwy 28 Bypass.
    • Three (3) 10’ x 12’ roll‑up doors.
    • +/- 800 SF of office space with restroom & HVAC.
    • +/- 2400 SF of warehouse space with concrete slab flooring and 16’ ceiling height.
    Updated: Mar 5
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    Miracle Mile Commercial Building
    $9 SF/Yr
    4,000 SF

    Miracle Mile Commercial Building

    Approximately 4000 SF building for lease with high visibility.

    102 Miracle Mile Dr, Anderson, SC 29621
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    Renovated Office Building For Rent
    $1,300 /Mo
    1,300 SF

    Renovated Office Building For Rent

    Renovated office building with versatile space for rent.

    1311 South Murray Avenue, Anderson, SC 29624
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    Office Space Near Downtown Anderson
    $1,300 /Mo
    900 SF

    Office Space Near Downtown Anderson

    Office suite with three private offices, reception, and kitchenette.

    1214 North Main Street, Anderson, SC 29621
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    Modern Office Space Available
    $500 /Mo

    Modern Office Space Available

    Updated office space with 9 offices, conference room, and breakroom.

    521 N Mcduffie St, Anderson, SC 29621
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    Retail Space in Whitehall Commons
    $13 SF/Yr
    1,200 SF

    Retail Space in Whitehall Commons

    Retail or office space available in a high-traffic area.

    1486 Pearman Dairy Road, Anderson, SC 29625
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    Office Space Near Clemson Blvd
    $4,500 /Mo

    Office Space Near Clemson Blvd

    Strategically located office space off Anderson's premier commercial corridor.

    120 East West Parkway, Anderson, SC 29621
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    Renovated Office/Retail Space Available
    $15 SF/Yr
    1,200 SF

    Renovated Office/Retail Space Available

    Newly renovated 1,200 SF office/retail space for lease.

    1207 Whitehall Road, Anderson, SC 29625
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    Office Space Available for Lease
    $15 SF/Yr

    Office Space Available for Lease

    Office space available for lease in Anderson, SC.

    309 E Greenville St, Anderson, SC 29621
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    Downtown Anderson Office Space
    $12 SF/Yr

    Downtown Anderson Office Space

    Office space available for lease in downtown Anderson.

    211 West Whitner Street, Anderson, SC 29624
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    Office Space with Recent Upgrades
    $5,000 /Mo
    4,200 SF

    Office Space with Recent Upgrades

    Office space featuring new exterior paint and resurfaced parking lot.

    120 E West Pkwy, Anderson, SC
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    Office Space Available For Rent
    Contact for pricing
    4,550 SF

    Office Space Available For Rent

    Office space available with 4,550 square feet in Anderson.

    131 Straight Dr, Anderson, SC 29625
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    18,000 SF Retail Building For Lease
    Contact for pricing

    18,000 SF Retail Building For Lease

    18,000 SF Retail Building For Lease

    518 East Greer Street, Honea Path, SC 29654
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    18,000 SF Retail Building For Lease
    Contact for pricing

    18,000 SF Retail Building For Lease

    18,000 SF Retail Building For Lease

    518 East Greer Street, Honea Path, SC 29654
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    Professional Office Space Available
    Contact for pricing
    3,000 SF

    Professional Office Space Available

    Well-maintained office park near US 178/N. Main St.

    341 E Beltline Blvd, Anderson, SC
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    Retail/Office Space for Lease
    Contact for pricing

    Retail/Office Space for Lease

    Retail or office space available for lease at $1,000/month.

    69 Main St, Pelzer, SC 29669
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    Former Union High School Available
    Contact for pricing

    Former Union High School Available

    Former Union High School available for lease in Belton, SC.

    250 Union High Dr, Belton, SC 29627
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    Oak Point Plaza Retail Opportunity
    Contact for pricing
    57,107 SF

    Oak Point Plaza Retail Opportunity

    Multi-tenant plaza near I-85 and Clemson University for lease.

    4120-4126 Clemson Blvd, Anderson, SC 29621
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    Prime Commercial Space in Anderson
    Contact for pricing
    1,200 SF

    Prime Commercial Space in Anderson

    Newly renovated commercial space with high visibility on Pearman Dairy Road.

    1716 Pearman Dairy Rd, Anderson, SC 29625
    View details
    Based on your search, we've compiled 66 Potential Opportunities for your consideration. Besides 20 Active listings in Anderson County, SC, we suggest exploring alternatives. Similar 46 Properties for Sales.

    Explore Similar Spaces for Sale in Anderson County, SC

    Consider Similar Space for Sale. We found 46 Spaces matching your search parameters.

    Prime Office Space, Anderson SC
    $499,000
    0.25 Acres

    Prime Office Space, Anderson SC

    Move-in ready office building with high visibility and ample parking.

    2006 N Main Street, Anderson, SC 29621
    View details
    Move-In Ready Office Building
    $499,000
    0.25 Acres

    Move-In Ready Office Building

    Pristine office building with high visibility and ample parking.

    2006 N Main Street, Anderson, SC 29621
    View details
    Versatile Commercial Space, Anderson SC
    $685,000
    0.88 Acres

    Versatile Commercial Space, Anderson SC

    Expansive commercial property with high visibility and traffic.

    405 Pearman Dairy Road, Anderson, SC 29625
    View details
    Versatile Warehouse & Flex Space
    $475,000
    3.11 Acres

    Versatile Warehouse & Flex Space

    Commercial warehouse and flex space in South Anderson, SC.

    109 Waybrook Drive, Anderson, SC 29624
    View details

    Anderson County, SC Office properties & Spaces Leasing Opportunities Market Analysis

    Explore Office properties & Spaces leasing options in Anderson County, SC with 20 listings featured on our commercial real estate exchange. The current inventory includes 313,632,000 square feet of properties with an estimated lease value of $65 SF/Yr.

    Estimated lease rates for Office properties & Spaces in Anderson County, SC begin at $9 SF/Yr, with an average of $13 SF/Yr and extend to $15 SF/Yr.
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