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    Anderson County, SC Office Spaces for Lease

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    16 properties
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    First-Floor Medical/Professional Suite
    Updated: Jul 14
    First-Floor Medical/Professional Suite

    2315 N Main Street, Anderson, SC 29621

    $500/Mo
    Class A, two‑story all‑brick office building with 23,000 SF and large parking
    First‑floor private suite offering 100 SF
    Shared kitchenette and shared conference room within the suite area
    Signage available; maintenance, electric, and water included in the rent
    Previously occupied by an insurance agency
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    First-Floor Office Suite with Conference
    Updated: Jul 14
    First-Floor Office Suite with Conference

    2315 N Main Street, Anderson, SC 29621

    $650/Mo
    Class A, two‑story all‑brick office building with 23,000 SF and large on‑site parking
    Suite available: 250 SF on the first floor within a larger suite that offers other sizes
    Suite includes a shared kitchenette and conference room
    Maintenance, electric, and water are included in the rent
    Adjacent suites can be combined to create up to 500 SF (call for price)
    View details
    Professional Office Suite
    Professional Office Suite

    1924 McConnell Springs Road, Anderson, SC 29621

    $2,049/Mo

    Office suite includes three offices, a kitchenette, and a dedicated restroom within a professional office building.

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    Office Suite with High-End Finishes
    Office Suite with High-End Finishes

    1801 North Main Street, Anderson, SC 29621

    $18 SF/Yr
    1,800 sqft $2,700/Mo

    Well-finished office suite with private offices, conference space, ample parking, and strong visibility for professional teams.

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    First-Floor Class A Office Suite
    First-Floor Class A Office Suite

    2315 N Main Street, Anderson, SC 29621

    $3,400/Mo

    First-floor office suite in a two-story all-brick Class A building with on-site utilities and maintenance included.

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    First-Floor Office Suite
    First-Floor Office Suite

    2315 N Main Street, Anderson, SC 29621

    $3,400/Mo

    First-floor suite with 8 private offices, kitchen, and conference room in a Class A, all-brick building.

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    Renovated Office Building For Rent
    Renovated Office Building For Rent

    1311 South Murray Avenue, Anderson, SC 29624

    $1,300/Mo
    1,300 sqft $12 SF/Yr

    Renovated office building with versatile space for rent.

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    Office Space Near Downtown Anderson
    Office Space Near Downtown Anderson

    1214 North Main Street, Anderson, SC 29621

    $1,200/Mo
    900 sqft $16 SF/Yr

    Office suite with three private offices, reception, and kitchenette.

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    Modern Office Space Available
    Modern Office Space Available

    521 N Mcduffie St, Anderson, SC 29621

    $500/Mo

    Updated office space with 9 offices, conference room, and breakroom.

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    Multi-Building Industrial Campus
    Multi-Building Industrial Campus

    245 WELPINE RD, Pendleton, SC 29670

    Contact for pricing
    19,550 sqft

    Industrial campus with front office and reception, multiple warehouses, and two ingress/egress for practical contractor use.

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    Office Spaces Available For Lease
    Office Spaces Available For Lease

    210 N Mcduffie St, Anderson, SC 29621

    $550/Mo

    Office spaces available for lease in Anderson, South Carolina.

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    East Greenville Street Office Space
    East Greenville Street Office Space

    1403 East Greenville Street, Anderson, SC 29621

    Contact for pricing
    2,000 sqft

    Office or medical suite with ample parking and high visibility.

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    Downtown Anderson Office Space
    Downtown Anderson Office Space

    211 West Whitner Street, Anderson, SC 29624

    $12 SF/Yr

    Office space available for lease in downtown Anderson.

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    Former Bank Branch with Drive-Thru
    Former Bank Branch with Drive-Thru

    3898 Liberty Highway, Anderson, SC 29621

    $18 SF/Yr

    Former bank branch with drive-thru located near major retailers.

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    Professional Office Space Available
    Professional Office Space Available

    341 E Beltline Blvd, Anderson, SC

    Contact for pricing
    3,000 sqft

    Well-maintained office park near US 178/N. Main St.

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    18,000 SF Retail Building For Lease
    18,000 SF Retail Building For Lease

    518 East Greer Street, Honea Path, SC 29654

    Contact for pricing

    18,000 SF Retail Building For Lease

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    Based on your search, we've compiled 53 Potential Opportunities for your consideration. Besides 16 Active listings in Anderson County, SC, we suggest exploring alternatives. Similar 33 Properties for Sales.

    Similar Spaces for Sale in Anderson County, SC

    Consider Similar Space for Sale. We found 33 Spaces matching your search parameters.

    Adaptable Commercial Property on Highway
    Adaptable Commercial Property on Highway

    6114 HWY 76, Pendleton, SC 29670

    $925,000
    8,700 sqft 1.00 AC lot

    Warehouse and office buildings with high traffic frontage on Highway.

    View details
    Williamston Commercial Opportunity For Sale
    Williamston Commercial Opportunity For Sale

    203 N Hamilton Street, Williamston, SC 29697

    $279,900
    1,850 sqft 0.47 AC lot

    Commercial building with rental potential in Williamston, South Carolina.

    View details
    Flex-Use Retail and Office Building
    Flex-Use Retail and Office Building

    1804 S McDuffie Street, Anderson, SC 29624

    $255,000
    0.28 AC lot

    Fully fenced flex-use building with an oversized side-entry garage and heated main space for retail, office, or dining concepts.

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    Commercial Property Near Downtown Anderson
    Commercial Property Near Downtown Anderson

    3499 East River Street, Anderson, SC 29621

    $429,000
    2,430 sqft 0.64 AC lot

    Well-maintained flex building with office and warehouse space.

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    Office Building with Off-Street Parking
    Office Building with Off-Street Parking

    2006 N Main Street, Anderson, SC 29621

    $499,000
    0.25 AC lot

    Office building with paved front and rear parking, multiple entrances, and hard-surface flooring throughout the main level.

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    Versatile Office Building with Parking
    Versatile Office Building with Parking

    713 Anderson Street, Belton, SC 29627

    $290,000
    0.45 AC lot

    Functional office building with ample parking in Belton, SC.

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    Belton Commercial Buildings and Land
    Belton Commercial Buildings and Land

    1513 Anderson St, Belton, SC 29627

    $650,000
    8,180 sqft 10.44 AC lot

    Two commercial buildings and land available in Belton, SC.

    View details
    Anderson Office Building For Sale
    Anderson Office Building For Sale

    131 Straight Drive, Anderson, SC 29625

    $649,000
    4,550 sqft

    Well-located office building near Clemson Boulevard and AnMed Medical Center.

    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Prime Development Opportunity in Greenville
    Prime Development Opportunity in Greenville

    39 Airpark Ct, Greenville, SC 29607

    Contact for pricing

    1.27 acre interstate-visible land for ground lease or build-to-suit.

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    Land Lease Opportunity in Waxhaw
    Land Lease Opportunity in Waxhaw

    5325 Waxhaw Marvin Road, Waxhaw, NC 28173

    $8,000/Mo

    5.341-acre commercial land for lease in a high-growth area.

    View details
    Commercial Land Near Interstate 40
    Commercial Land Near Interstate 40

    310 Goose Creek Road, Dandridge, TN 37725

    $499,900/Mo
    1,860 sqft $3,225 SF/Yr

    3.96 acres with high visibility near Interstate 40.

    View details
    Commercial Land in Powder Springs
    Commercial Land in Powder Springs

    2125 Brownsville Road, Powder Springs, GA 30127

    $3,000/Mo
    2,690 sqft $13.38 SF/Yr

    4.5 acres of commercial land for ground lease.

    View details

    Anderson County, SC Office Spaces Market Trends and Statistics

    Explore Office Spaces leasing options in Anderson County, SC with 16 listings featured on our commercial real estate exchange. The current inventory includes 4,000 square feet of properties with an estimated lease value of $46 SF/Yr.

    Estimated lease rates for Office Spaces in Anderson County, SC begin at $12 SF/Yr, with an average of $15.33 SF/Yr and extend to $18 SF/Yr.
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