South Carolina Mixed-use properties for Rent & Lease

Updated: Sep 8

New Mixed-Use Space

5100 Highway 17 Bypass, Murrells Inlet, SC 29576

$3,125/Mo

2,500 sqft 1.90 AC lot

2,500 SF available within a 12,000 SF mixed‑use building
Can be configured as two 1,250 SF suites or one 2,500 SF space
Direct exposure on Highway 17 Bypass with approximately 36,700 vehicles per day
1.9‑acre site with ample parking
Projected completion March 2027

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Updated: Feb 23

Mixed-Use Office Property

413 Main Street S, New Ellenton, SC 29809

$1,100/Mo

840 sqft

840 square feet of mixed‑use office space
NNN lease structure
Bathroom included
Constructed in 1948
Located at 413 Main Street S, New Ellenton, SC 29809

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Build-Out-Ready Mixed-Use Space

413 Main Street S, New Ellenton, SC 29809

$800/Mo

510 sqft

Compact office or mixed-use space in New Ellenton with an NNN lease structure.

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Oceanfront End-Cap Retail Space

700 N Ocean Blvd, Myrtle Beach, SC 29577

$27 SF/Yr

4,251 sqft

Ground-floor retail suite with an oceanfront patio and sidewalk access to the boardwalk.

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Mixed-Use Property with Loading Dock

11 Mathews Drive, Hilton Head Island, SC 29926

$18 SF/Yr

1.00 AC lot

Commercially zoned space includes a loading dock and rear pull-up door.

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Mixed-Use Property in Cayce, SC

528-532 Knox Abbott Dr, Cayce, SC 29033

$825/Mo

7,541 sqft

Mixed-use property suitable for redevelopment, retail, or office use.

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Rivers Avenue Renovated Flex Space

5640 Rivers Ave, Charleston, SC 29406

$18 SF/Yr

4,420 sqft

Renovated flex space available on highly traveled retail strip.

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New Bluffton Flex and Retail

5 Kitties Landing, Bluffton, SC 29910

$25 SF/Yr

8,000 sqft

New flex and retail buildings in the heart of Bluffton.

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Renovated Storefront Retail Space

2295 Hoffmeyer Road - Storefront B, Florence, SC 29501

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7,405 sqft

A renovated retail suite includes new HVAC, sprinkler protection, and access to on-site parking.

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Historic Mixed-Use Space

102 Exchange Street Basement, Pendleton, SC 29670

$3,100/Mo

Basement commercial space offered as a shell for tenant upfit.

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Mixed-Use Development on Highway 41

1031 & 1039 Hwy 41, Mount Pleasant, SC 29466

$28 SF/Yr

16,000 sqft

Multi-building mixed-use development with retail and office space.

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Mixed-Use Marketplace with Restaurant Space

1802 Drayton Road, Drayton, SC 29333

$16 SF/Yr

Lease offerings include creative offices, a second-generation restaurant, and event space.

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Office Units with Flexible Sizes

61 Broad St, Charleston, SC 29401

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1,230 sqft

Office units are offered in multiple configurations within a building that maintains separate access for residential floors.

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Mixed-Use Retail and Entertainment Center

1740 Towne Centre Way, Mount Pleasant, SC 29464

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3,713 sqft

Towne Centre offers retail and dining alongside Regal Cinemas, Belk, and Hyatt Place.

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Mixed-Use Shopping Center Space

966 Houston Northcutt Blvd, Mt Pleasant, SC 29464

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2,750 sqft

Commercial space within a center serving retail, office, and hotel uses.

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Historic Spartanburg Mixed-Use Retail Space

174 E Main St, Spartanburg, SC 29306

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4,709 sqft

Retail space available in historic mixed-use building in downtown Spartanburg.

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Renovated Mixed-Use Storefront

2295 Hoffmeyer Road - Storefront A, Florence, SC 29501

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Flexible commercial space combines a two-level office component with adaptable interior area and dock access.

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Planned Mixed-Use Development Opportunity

565-573 Chapin Road, Chapin, SC 29036

$26 SF/Yr

Mixed-use development opportunity at Chapin Road and Primrose Lane.

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Spartanburg Flexible Space For Rent

1201 Union, Spartanburg, SC

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34,053 sqft 4.14 AC lot

Flexible space suitable for retail or mixed-use purposes.

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Mixed-Use Development Property

701 Easley Bridge Rd, Greenville, SC 29611

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10,000 sqft

Flexible space options include office, retail, and light industrial uses within a mixed-use campus.

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Adaptive Reuse Mixed-Use Campus

1501 King Street, Charleston, SC 29405

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2,227 sqft

A mixed-use campus blending historic warehouse architecture with modern design, with curated outdoor courtyards and gathering areas.

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Three-Space Mixed-Use Property

695 Meeting Street, Charleston, SC 29403

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Lease offering combines retail and office space with customer parking at a walkable Charleston location.

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Mixed-Use Property with Rooftop Space

83 Mary Street # 200, Charleston, SC 29403

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Open-plan commercial floors provide natural light, high ceilings, and flexible space for retail, office, or creative uses.

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Adaptive Reuse Mixed-Use Property

1501 King Street, Charleston, SC 29405

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3,345 sqft

Flexible commercial space within a campus combining food, retail, wellness, and office uses around landscaped courtyards.

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South Carolina Mixed-use properties Market Trends and Statistics

Explore Mixed-use properties leasing options in South Carolina with 37 listings featured on our commercial real estate exchange. The current inventory includes 153,936 square feet of properties with an estimated lease value of $220.84.

Estimated lease rates for Mixed-use properties in South Carolina begin at $1.31 SF/Yr, with an average of $18.40 SF/Yr and extend to $28 SF/Yr.