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    Florence County, SC Office Spaces for Lease

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    7 properties
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    Dental Medical Office Suite
    Updated: Oct 1
    Dental Medical Office Suite

    417 W Cheves Street, Florence, SC 29501

    $3,000/Mo
    1,850 sqft
    1,850 square feet in a brick building constructed in 1979
    Dental layout with 4 operatories, laboratory, break room, and private office
    Paneled waiting room and large reception area
    Some dental equipment remains in place
    On‑site private parking
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    Office Building Near City Center
    Updated: Sep 5
    Office Building Near City Center

    129 S Coit Street, Florence, SC 29501

    $1,400/Mo
    1,320 sqft
    1,320‑square‑foot office building
    Adjacent to City Center
    Built in 1959
    129 S Coit Street, Florence, SC 29501
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    Flexible Office Unit
    Flexible Office Unit

    1604 2nd Loop Rd, Florence, SC 29501

    $1,800/Mo
    1,000 sqft

    Commercial space with adaptable layout, parking, and access for office, medical, retail, or service businesses.

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    Medical Office with Four Operatories
    Medical Office with Four Operatories

    417 West Cheves Street, Florence, SC 29501

    Contact for pricing
    1,850 sqft

    A patient reception area, laboratory, private office, break room, and two restrooms support a functional clinical layout.

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    Character Office Unit
    Character Office Unit

    201 Graham Street, Florence, SC 29501

    Contact for pricing

    Historic office layout with private rooms, conference space, reception, and kitchenette.

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    Florence Commercial Space For Rent
    Florence Commercial Space For Rent

    2843 W Palmetto St, Florence, SC 29501

    Contact for pricing

    Commercial space suitable for office, professional, or retail use.

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    Modern Office Space For Rent
    Modern Office Space For Rent

    2701 Alex Lee Blvd, Florence, SC 29506

    Contact for pricing
    7,145 sqft

    7,145 SF customizable office space in Florence, SC.

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    Based on your search, we've compiled 22 Potential Opportunities for your consideration. Besides 7 Active listings in Florence County, SC, we suggest exploring alternatives. Similar 15 Properties for Sales.

    Similar Spaces for Sale in Florence County, SC

    Consider Similar Space for Sale. We found 15 Spaces matching your search parameters.

    Freestanding Storefront Building
    Freestanding Storefront Building

    205 W Main St, Lake City, SC 29560

    $700,000
    5,410 sqft

    Downtown setting near businesses, banks, restaurants, and public services supports multiple commercial use options.

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    Historic Downtown Office Building
    Historic Downtown Office Building

    260 W Evans St, Florence, SC 29501

    $2,700,000
    16,000 sqft 1.47 AC lot

    A 16,000-square-foot historic office building with multiple suites, including a law firm and other tenants, plus over 100 parking spaces.

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    Historic Office Building
    Historic Office Building

    248-260 W Evans st., Florence, SC 29501

    $2,700,000
    16,304 sqft 1.47 AC lot

    Established professional layout with multiple occupants, meeting rooms, reception space, and dedicated parking in downtown Florence.

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    Historic Downtown Florence Building For Sale
    Historic Downtown Florence Building For Sale

    248,258, and 268 W. Evans St., Florence, SC 29501

    $2,700,000
    16,304 sqft 1.47 AC lot

    16,000 SF historic building in downtown Florence for sale.

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    Medical Office with Exam Rooms
    Medical Office with Exam Rooms

    1706 2nd Loop Rd., Florence, SC 29501

    $1,650,000
    8,291 sqft 1.34 AC lot

    Brick medical facility with exam rooms, administrative offices, covered patient arrival, and dedicated on-site parking.

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    Medical Office Building with Sinks
    Medical Office Building with Sinks

    102 West Market Street, Timmonsville, SC 29161

    Contact for pricing
    4,856 sqft 0.34 AC lot

    B-4-zoned office building with separate entrances, reception areas, and adaptable medical-office infrastructure.

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    Flexible Retail and Office Building
    Flexible Retail and Office Building

    821 2nd Loop Road, Florence, SC 29505

    Contact for pricing
    5,400 sqft

    New construction with adaptable suites, shell interiors, and on-site parking along a heavily traveled commercial corridor.

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    Office-Warehouse Flex Facility
    Office-Warehouse Flex Facility

    1829 Habersham Square, Florence, SC 29501

    Contact for pricing
    5,000 sqft 0.81 AC lot

    Office space with three private offices and a reception area complements a warehouse with two drive-in doors.

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    Historic Downtown Office Building
    Historic Downtown Office Building

    248-260 W Evans st., Florence, SC 29506

    Contact for pricing
    16,304 sqft 1.47 AC lot

    Historic office building in downtown Florence with multiple tenant suites and over 100 parking spaces.

    View details
    Freestanding Office Building For Sale
    Freestanding Office Building For Sale

    1221 West Evans Street, Florence, SC 29501

    Contact for pricing
    1,085 sqft

    Leased office building with immediate income potential in Florence.

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    Freestanding Office Building with Parking
    Freestanding Office Building with Parking

    1500 West Evans Street, Florence, SC 29501

    Contact for pricing
    2,523 sqft

    Well-maintained brick office with private offices, reception, open workspace, and paved side and rear parking.

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    Office/Retail Conversion Opportunity
    Office/Retail Conversion Opportunity

    2901 W Palmetto Street, Florence, SC 29501

    Contact for pricing
    2,600 sqft 1.60 AC lot

    2600 SF residence on 1.6 acres, suitable for conversion.

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    Office Building with Efficiency Apartment
    Office Building with Efficiency Apartment

    1506 W Palmetto Street, Florence, SC 29501

    Contact for pricing

    Three main-level rooms and a den are complemented by a downstairs kitchen and dining area.

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    Historic Downtown Florence Commercial Property
    Historic Downtown Florence Commercial Property

    329 N Irby St, Florence, SC 29501

    Contact for pricing
    12,411 sqft 1.55 AC lot

    Historic building in downtown Florence, suitable for commercial use.

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    South Irby Street Commercial Lot
    South Irby Street Commercial Lot

    623 South Irby Street, Florence, SC 29501

    Contact for pricing
    0.46 AC lot

    0.46 acre lot suitable for retail or office development.

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    Florence County, SC Office Spaces Market Trends and Statistics

    Explore Office Spaces leasing options in Florence County, SC with 7 listings featured on our commercial real estate exchange. The current inventory includes 13,165 square feet of properties with an estimated lease value of $53.79.

    Estimated lease rates for Office Spaces in Florence County, SC begin at $12.73 SF/Yr, with an average of $17.93 SF/Yr and extend to $21.60 SF/Yr.
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    Featured Florence County Real Estate Agencies

    Realmo connects you with licensed Florence County CRE brokers providing property specifications, local market pricing, and commercial transaction underwriting support.

    Coldwell Banker McMillan and Associates
    419 S.Coit Street Florence, SC 29501
    Phone: 18436017710
    CBFlorence.com
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