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    Pickens County, SC Office Spaces for Lease

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    Greenville, SC Columbia, SC Charleston, SC
    8 results
    Premium Office Space in Easley
    $2,250/Mo
    Premium Office Space in Easley

    1818 E Main Street Park, Easley, SC 29640

    Professional office space with excellent visibility and ample parking.
    • Premium office complex with global tenants.
    • Convenient location directly off Hwy 123, close to Hwy 93, I‑85 corridor, Downtown Greenville, Clemson and Powdersville.
    • Ample free onsite parking.
    • Excellent visibility and walkability to restaurants and retail.
    • Versatile floor plans with high ceilings and large open areas.
    Updated: Apr 20
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    Retail/Office Space For Rent
    Contact for pricing
    1,200 SF
    Retail/Office Space For Rent

    5208-A Calhoun Memorial Hwy, Easley, SC 29640

    Retail/office space with high visibility and ample parking.
    • Excellent visibility from SC Hwy 123 with high daily traffic (30,000+ VPD).
    • Located across from Ingles, Taco Bell, and Chick‑fil‑A.
    • Co‑tenants include AFC Urgent Care‑Bon Secours, CORA Physical Therapy, and Miracle‑Ear.
    • Ample on‑site parking available.
    • Well‑maintained building.
    Updated: May 11
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    Office Space in Easley, SC
    $13 SF/Yr
    2,589 SF
    Office Space in Easley, SC

    Office space available for lease in Easley, South Carolina.

    810 Powdersville Rd, Easley, SC

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    Easley Office Space Available
    $14 SF/Yr
    2,100 SF
    Easley Office Space Available

    Office space available for lease in Easley, South Carolina.

    836 Powdersville Rd, Easley, SC

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    Easley Office Space Available
    $11 SF/Yr
    3,422 SF
    Easley Office Space Available

    Office space available for rent in Easley, South Carolina.

    109 Fleetwood Dr, Easley, SC

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    Penthouse Office Floor For Rent
    $15 SF/Yr
    Penthouse Office Floor For Rent

    Penthouse office floor in a centrally located professional office complex.

    1818 E Main St, Easley, SC 29640

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    Spacious Office Suite on Main
    Contact for pricing
    Spacious Office Suite on Main

    Functional office suite with natural light and convenient access.

    1814 E Main St, Easley, SC 29640

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    Medical Office Building For Rent
    $11 SF/Yr
    18,631 SF
    Medical Office Building For Rent

    Medical office building offering approximately 18,631 square feet for lease.

    109 Fleetwood Dr, Easley, SC 29640

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    Based on your search, we've compiled 24 Potential Opportunities for your consideration. Besides 8 Active listings in Pickens County, SC, we suggest exploring alternatives. Similar 12 Properties for Sales.

    Similar Spaces for Sale in Pickens County, SC

    Consider Similar Space for Sale. We found 12 Spaces matching your search parameters.

    Easley Commercial Property on Highway
    $239,900
    0.49 Acres
    Easley Commercial Property on Highway

    High-visibility commercial lot near downtown Easley with office building.

    609 E Main Street, Easley, SC 29640

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    Easley Commercial Opportunity on Highway
    $239,900
    0.49 Acres
    Easley Commercial Opportunity on Highway

    High-visibility commercial lot near downtown Easley with office building.

    609 E Main Street, Easley, SC 29640

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    Pickens Commercial Office Building Investment
    $350,000
    0.16 Acres
    Pickens Commercial Office Building Investment

    Commercial office building near Pickens County Court House.

    113 Court Street, Pickens, SC 29671

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    Commercial Office Building Investment Opportunity
    $350,000
    2,400 SF
    Commercial Office Building Investment Opportunity

    Commercial office building near Pickens County Court House for sale.

    113 Court Street, Pickens, SC 29671

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    Multi-Tenant Investment Opportunity
    $499,900
    6,250 SF
    Multi-Tenant Investment Opportunity

    6,250 SF multi-tenant investment opportunity in Easley, SC.

    1649 East Main Street, Easley, SC 29640

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    Easley Showroom/Office/Warehouse For Sale
    $1,400,000
    18,000 SF
    Easley Showroom/Office/Warehouse For Sale

    18,000 SF showroom/office/warehouse in Easley, SC. Owner/user opportunity.

    1017 Powdersville Rd, Easley, SC 29642

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    Medical Office Near Prisma Health
    $1,500,000
    4,038 SF
    Medical Office Near Prisma Health

    4,038 SF available near Prisma Health Baptist Easley Hospital.

    201 Richard St, Easley, SC

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    Easley Office Building For Sale
    $549,000
    7,163 SF
    Easley Office Building For Sale

    Office building on a 0.29-acre lot, suitable for owner-occupant.

    401 E 1st Ave, Easley, SC

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    Historic Pickens Textile Mill Opportunity
    $3,200,000
    72,000 SF
    Historic Pickens Textile Mill Opportunity

    23.79-acre site with 72,000 SF warehouse and office space.

    203 Woodrow St, Pickens, SC 29671

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    Industrial Building with Long-Term Tenant
    Contact for pricing
    182,508 SF
    Industrial Building with Long-Term Tenant

    182,508 SF light manufacturing building with long-term tenant.

    1208 Old Norris Rd, Liberty, SC

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    Medical Site in Patrick Square
    $499,000
    8,000 SF
    Medical Site in Patrick Square

    Medical site opportunity near Clemson University in Patrick Square.

    Chapman Hill Rd, Clemson, SC 29631

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    Vacant Land Parcels For Sale
    $600,000
    Vacant Land Parcels For Sale

    Three vacant land parcels ideal for retail, office, or medical.

    0 Ann Street, Pickens, SC 29671

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    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Prime Development Opportunity in Greenville
    Contact for pricing
    Prime Development Opportunity in Greenville

    1.27 acre interstate-visible land for ground lease or build-to-suit.

    39 Airpark Ct, Greenville, SC 29607

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    Commercial Land Near Interstate 40
    $499,900 SF/Yr
    1,860 SF
    Commercial Land Near Interstate 40

    3.96 acres with high visibility near Interstate 40.

    310 Goose Creek Road, Dandridge, TN 37725

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    Land Lease Opportunity in Waxhaw
    $8,000/Mo
    Land Lease Opportunity in Waxhaw

    5.341-acre commercial land for lease in a high-growth area.

    5325 Waxhaw Marvin Road, Waxhaw, NC 28173

    View details
    Prime Commercial Land For Lease
    $285,000 SF/Yr
    Prime Commercial Land For Lease

    3 acres of B-3 zoned land with city amenities.

    220 Silver Lake Road, Church Hill, TN 37642

    View details

    Pickens County, SC Office Spaces Leasing Opportunities Market Analysis

    Explore Office Spaces leasing options in Pickens County, SC with 8 listings featured on our commercial real estate exchange. The current inventory includes 26,742 square feet of properties with an estimated lease value of $49 SF/Yr.

    Estimated lease rates for Office Spaces in Pickens County, SC begin at $11 SF/Yr, with an average of $12 SF/Yr and extend to $14 SF/Yr.
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