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    Pickens County, SC Office Spaces for Lease

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    10 properties
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    Executive Office Units With Flexible Layouts
    Updated: Apr 20
    Executive Office Units With Flexible Layouts

    1814 E Main Street Park, Easley, SC 29640

    $2,780/Mo
    Flexible office layouts with open areas for cubicles, conference, or training use
    Elevators provide access to all floors; buildings include high ceilings and plenty of windows
    Full kitchen facilities with furnishings available upon request
    Free on‑site parking and restaurants within walking distance
    High‑speed fiber lines and 24‑hour security camera monitoring available
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    Office Units with Flexible Floor Plans
    Updated: Apr 20
    Office Units with Flexible Floor Plans

    1818 E Main Street Park, Easley, SC 29640

    $1,795/Mo
    Flexible office layouts with open areas for cubicles, conferences, or training
    High ceilings, abundant windows, and elevators serving all floors
    Free on‑site parking available
    High‑speed fiber lines available
    24‑hour security camera monitoring available
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    Retail Space with Basement Office
    Retail Space with Basement Office

    6818 Calhoun Memorial, Easley, SC 29640

    $1,350/Mo
    2,500 sqft

    Highway-facing commercial property combines flexible retail frontage with basement offices and on-site parking.

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    First-Floor Retail and Office Suites
    First-Floor Retail and Office Suites

    125 Anderson Highway, Clemson, SC 29631

    $25 SF/Yr

    Three first-floor suites are available inside a 150-room, 500-bed student housing community on a high-traffic Clemson corridor.

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    Retail Office Suite with Frontage
    Retail Office Suite with Frontage

    838 Powdersville Rd, Easley, SC 29642

    $14 SF/Yr

    Convenient retail/office suite in Carolina Center with 1,675 feet of road frontage on Powdersville Road.

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    Office Building Adjacent to Hospital
    Office Building Adjacent to Hospital

    201 Richard St, Easley, SC 29640

    Contact for pricing
    4,036 sqft

    Office space available near Prisma Health Baptist Easley Hospital, with repaving and restriping planned for the parking lot.

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    Retail or Office Suite
    Retail or Office Suite

    5823 Calhoun Memorial Highway, Easley, SC 29640

    Contact for pricing
    1,211 sqft

    Suite 1A provides flexible retail or office space within a highly visible shopping center with ample parking.

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    Office Suite with Boulevard Signage
    Office Suite with Boulevard Signage

    501 Forest Lane, Clemson, SC 29631

    Contact for pricing

    Three private offices support a flexible professional workspace with reception and meeting areas.

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    Private Office Unit
    Private Office Unit

    106 Earle St, Clemson, SC 29631

    Contact for pricing

    Two work areas, storage, a private bathroom, and utilities support flexible day-to-day operations.

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    Penthouse Office Floor For Rent
    Penthouse Office Floor For Rent

    1818 E Main St, Easley, SC 29640

    Contact for pricing

    Penthouse office floor in a centrally located professional office complex.

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    Based on your search, we've compiled 37 Potential Opportunities for your consideration. Besides 10 Active listings in Pickens County, SC, we suggest exploring alternatives. Similar 26 Properties for Sales.

    Similar Spaces for Sale in Pickens County, SC

    Consider Similar Space for Sale. We found 26 Spaces matching your search parameters.

    Multi-Tenant Office Condominium Units
    Multi-Tenant Office Condominium Units

    1824 E Main St, Easley, SC 29640

    $210,000
    7,808 sqft 0.70 AC lot

    Four office condominium units in Easley, with two vacant for immediate occupancy and two occupied under existing leases.

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    Wedding Venue With Open Event Space
    Wedding Venue With Open Event Space

    3825 Saluda Dam Road, Easley, SC 29640

    $2,000,000
    2.13 AC lot

    Heated and cooled commercial facility with flexible event, office, classroom, kitchen, restroom, and support areas.

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    Live-Work Property with Detached Shop
    Live-Work Property with Detached Shop

    155 Farrs Bridge Rd, Pickens, SC 29671

    $225,000
    1,500 sqft 0.47 AC lot

    Two-bedroom residence with a separate shop and covered area supports combined personal and commercial use.

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    Multi-Tenant Investment Opportunity
    Multi-Tenant Investment Opportunity

    1649 East Main Street, Easley, SC 29640

    $475,000
    6,250 sqft

    6,250 SF multi-tenant investment opportunity in Easley, SC.

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    Office Building Near Prisma Health Baptist Easley Hospital
    Office Building Near Prisma Health Baptist Easley Hospital

    201 Richard St, Easley, SC 29640

    Contact for pricing
    8,074 sqft

    Office space available near Prisma Health Baptist Easley Hospital, with a parking lot repaving and restriping scheduled for spring.

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    Office Building with NNN Lease
    Office Building with NNN Lease

    5031 Highway 153, Easley, SC 29642

    Contact for pricing
    25,000 sqft

    Office facility offering a defined lease term before planned vacant possession.

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    Multi-Tenant Medical Office Building
    Multi-Tenant Medical Office Building

    109 Fleetwood Drive, Easley, SC 29640

    Contact for pricing
    18,631 sqft

    Multi-tenant configuration provides dedicated space for medical office users.

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    Two-Building Office Property
    Two-Building Office Property

    4020 and 4028 Calhoun Memorial Hwy, Easley, SC 29640

    Contact for pricing
    7,500 sqft 3.50 AC lot

    Office asset with multiple buildings and established construction suitable for varied commercial operations.

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    Office Building with Two Units
    Office Building with Two Units

    113 Court Street, Pickens, SC 29671

    $350,000
    0.16 AC lot

    Brick office property with distinctive wood detailing, flexible meeting areas, and a private courtyard adjoining the Pickens County Court House.

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    Office Building with Brick Courtyard
    Office Building with Brick Courtyard

    113 Court St, Pickens, SC 29671

    $350,000

    Two-unit office property with meeting space, private courtyard, and on-site parking.

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    Main Street Storefronts
    Main Street Storefronts

    131 /133 W Main St, Pickens, SC 29671

    $350,000

    Three commercial spaces offer retail, service, or office use across Main and Irwin Streets.

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    NNN Medical Office Building
    NNN Medical Office Building

    1617 E Main St, Easley, SC 29640

    Contact for pricing
    2,726 sqft

    Corporate-guaranteed dental lease with 6.5 years remaining and four renewal options.

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    Multi-Tenant Retail Center
    Multi-Tenant Retail Center

    379 Old Greenville Highway, Clemson, SC 29631

    Contact for pricing
    10,006 sqft 1.09 AC lot

    Freestanding center combines retail and office suites with brick construction, glass storefronts, and a monument sign.

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    Two-Level Office Building
    Two-Level Office Building

    837 Pendleton St, Pickens, SC 29671

    Contact for pricing
    3,872 sqft 0.76 AC lot

    Configured with multiple private rooms, meeting areas, kitchen facilities, and on-site parking.

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    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Prime Development Opportunity in Greenville
    Prime Development Opportunity in Greenville

    39 Airpark Ct, Greenville, SC 29607

    Contact for pricing
    1.27 AC lot

    1.27 acre interstate-visible land for ground lease or build-to-suit.

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    Pickens County, SC Office Spaces Market Trends and Statistics

    Explore Office Spaces leasing options in Pickens County, SC with 10 listings featured on our commercial real estate exchange. The current inventory includes 7,747 square feet of properties with an estimated lease value of $45.48.

    Estimated lease rates for Office Spaces in Pickens County, SC begin at $6.48 SF/Yr, with an average of $15.16 SF/Yr and extend to $25 SF/Yr.
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