South Carolina Commercial Real Estate for Lease

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Columbia, SC Greenville, SC Charleston, SC North Charleston, SC Myrtle Beach, SC Spartanburg, SC Rock Hill, SC Summerville, SC
2,670 properties
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Single-Room Office Unit
Updated: Aug 5
Single-Room Office Unit

918 Houndslake Drive, Aiken, SC 29803

$534/Mo
7,076 sqft
7,076‑square‑foot multi‑tenant office building
Single‑room office unit with shared waiting and reception areas
Lower‑level common kitchen, shared bathrooms, and shower
Utilities and shared internet included
Laundry facility available for tenant use
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Medical Office Space with Multiple Offices
Updated: Jul 31
Medical Office Space with Multiple Offices

407 N Salem Avenue, Sumter, SC 29150

$7,337/Mo
7,337 sqft 1.13 AC lot
7,337‑square‑foot medical office property
Layout includes numerous rooms, offices, and storage areas
1.13‑acre site at 407 N Salem Avenue, Sumter, SC 29150
Brick and block construction with tile and carpet flooring
Central air conditioning and heat pump heating
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New Mixed-Use Space
New Mixed-Use Space

5100 Highway 17 Bypass, Murrells Inlet, SC 29576

$3,125/Mo
2,500 sqft 1.90 AC lot

New construction supports flexible medical, professional office, and specialty retail configurations with direct exposure on the Highway 17 Bypass.

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Flexible Retail Showroom Space
Flexible Retail Showroom Space

144 Southport Rd, Spartanburg, SC 29306

$14.95 SF/Yr
5,800 sqft

Flexible commercial space combines a retail showroom with conditioned warehouse capacity and potential outdoor storage.

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Historic Retail Space with Loft Areas
Historic Retail Space with Loft Areas

110 E Main Street, Union, SC 29379

$2,300/Mo
4,200 sqft 0.10 AC lot

Character-rich commercial space with flexible areas, exposed brick, arched windows, and built-in shelving.

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Renovated Medical Office Suite
Renovated Medical Office Suite

4310 Highway 17 Business, Murrells Inlet, SC 29576

$8,000/Mo
3,557 sqft 3.00 AC lot

Recently renovated Class A space with shared patient amenities, dedicated elevators, and services included in the lease package.

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One-Room Office Unit
One-Room Office Unit

918 Houndslake Drive, Aiken, SC 29803

$534/Mo
120 sqft 2.07 AC lot

Utilities and shared internet are included, with common reception areas and a lower-level kitchen.

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Storefront Property with Courtyard
Storefront Property with Courtyard

1623 Highway 501, Myrtle Beach, SC 29577

$10,000/Mo
6,700 sqft

The property includes a full kitchen and a private courtyard for indoor and outdoor commercial space.

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Former Elementary School Campus
Former Elementary School Campus

1403 Highway 90, Conway, SC 29526

$6,000/Mo
15,000 sqft 6.00 AC lot

Two-building campus with classrooms, gathering space, stage, and commercial kitchen in a flexible CFA district.

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Single-Story Professional Office Units
Single-Story Professional Office Units

212 Newberry Street NW, Aiken, SC 29801

$4,800/Mo
3,214 sqft

Configured for professional users with private rooms, meeting space, support areas, and on-site parking.

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Brewery/Restaurant Space with Patio
Brewery/Restaurant Space with Patio

250 Mill St, Taylors, SC 29687

$9 SF/Yr
8,000 sqft

Open-plan hospitality space with a prep kitchen, dedicated restrooms, storage, loading facilities, and an outdoor deck.

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Second-Floor Office Unit
Second-Floor Office Unit

870 Inlet Square Dr., Murrells Inlet, SC 29576

$1,450/Mo
1,246 sqft 0.59 AC lot

HC-zoned office space positioned near major commercial and recreational destinations in Murrells Inlet.

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Professional Office Suite
Professional Office Suite

4728 Jenn Dr., Myrtle Beach, SC 29577

$3,100/Mo
1,500 sqft 1.90 AC lot

Configured with private offices, a conference room, reception area, and shared restroom access.

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Modern Medical Office Space
Modern Medical Office Space

391 Serpentine Drive, Spartanburg, SC 29303

$1,156/Mo
4,387 sqft

Modern medical suites with patient-care areas, elevator access, on-site parking, and proximity to Spartanburg Regional Medical Hospital.

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Renovated Storefront with Parking
Renovated Storefront with Parking

1111 Highway 17 N, Surfside Beach, SC 29575

$6,667/Mo
4,060 sqft 0.53 AC lot

C1-zoned commercial space with updated mechanical, plumbing, ceiling, and flooring improvements.

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Warehouse Unit With Loading Docks
Warehouse Unit With Loading Docks

2220 Highway 643, Myrtle Beach, SC 29577

$2,700/Mo
4,000 sqft 1.00 AC lot

LI-zoned warehouse space provides roll-up access and dock loading near major highway connections.

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Flex Building with Showroom
Flex Building with Showroom

6006 Two Notch Rd, Columbia, SC 29223

$7.50 SF/Yr
9,700 sqft

Lease space combines open retail presentation areas with warehouse capacity, offices, storage, and customer parking.

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Multi-Suite Office Property
Multi-Suite Office Property

1013 Surf Pine Dr., Surfside Beach, SC 29575

$4,500/Mo
3,419 sqft 0.60 AC lot

Flexible office configuration with private rooms, meeting areas, kitchen facilities, storage, and a secured outdoor yard.

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Turnkey Restaurant Space
Turnkey Restaurant Space

902 Gervais Street, Columbia, SC 29201

$4,767/Mo
4,767 sqft

Restaurant suite with mezzanine space, street frontage, available parking, and established dining and entertainment surroundings.

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Office Unit with Balcony
Office Unit with Balcony

4603 Oleander Dr., Myrtle Beach, SC 29577

$1,750/Mo
800 sqft 0.16 AC lot

The suite combines private offices with reception, kitchen, restroom, and paved on-site parking.

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Retail Showroom with Signage
Retail Showroom with Signage

146 Southport Road, Spartanburg, SC 29306

$14.95 SF/Yr
3,200 sqft

Retail space combines a customer-facing showroom with back-office and inventory areas for lease.

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Main Street Frontage Retail Space
Main Street Frontage Retail Space

673 Main St., North Myrtle Beach, SC 29582

$3,866/Mo
1,450 sqft 5.99 AC lot

Modern center space with prominent signage opportunities, on-site parking, and GC zoning.

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Multi-Suite Office Property
Multi-Suite Office Property

1013 Surf Pine Dr, Surfside Beach, SC 29575

$4,500/Mo
3,419 sqft 0.60 AC lot

Two-level commercial layout includes private offices, conference rooms, storage, and a fenced outdoor area.

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Two-Story Office Units
Two-Story Office Units

1089 Augusta Road, Warrenville, SC 29851

$7,000/Mo
9,000 sqft

Adaptable commercial space with CAT6 infrastructure, controlled entry, surveillance cameras, and public water and sewer service.

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South Carolina Commercial real estate Market Trends and Statistics

Explore Commercial real estate leasing options in South Carolina with 2670 listings featured on our commercial real estate exchange. The current inventory includes 75,951,971 square feet of properties with an estimated lease value of $14,733.

Estimated lease rates for Commercial real estate in South Carolina begin at $1.04 SF/Yr, with an average of $23.17 SF/Yr and extend to $533.80 SF/Yr.
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