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    South Carolina Commercial Real Estate for Lease

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    3,238 properties
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    Historic Retail Space with Loft Areas
    Updated: Jun 30
    Historic Retail Space with Loft Areas

    110 E Main Street, Union, SC 29379

    $2,300/Mo
    4,200 sqft
    For rent only: nearly 4,200 sq ft at 110 E Main St, Union
    Available at $2,300/month
    Building established in 1880, featuring original hardwood floors
    Historic interior details include exposed brick, arched windows, and built‑in shelves
    Includes main floor, basement, and two large loft areas for flexible use
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    Class A Medical Office Suite Renovated
    Updated: Jun 18
    Class A Medical Office Suite Renovated

    4310 Highway 17 Business, Murrells Inlet, SC 29576

    $8,000/Mo
    3,557 sqft
    Suite 103 offers 3,557 SF of Class A medical office space in a healthcare facility in Murrells Inlet, SC
    Tenant Improvement Allowance available for medical users to customize the space for clinical and operational needs
    Utilities, trash service, and janitorial service included in the rent
    Recently renovated building with dedicated patient and service elevators and a shared lobby with a complimentary coffee and beverage station
    Cosatron air purification system and Sentry 30 security system, plus an automatic water shut‑off system after business hours
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    Renovated Executive Office Suites Available
    Renovated Executive Office Suites Available

    46 Professional Ln., Pawleys Island, SC 29585

    $670/Mo
    2,808 sqft

    Newly renovated office suites in desirable Pawleys Island commercial corridor.

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    Free-Standing Two-Story Office Building
    Free-Standing Two-Story Office Building

    1089 Augusta Rd, Warrenville, SC 29851

    $7,000/Mo
    9,000 sqft

    Well-maintained two-story office building with security system, CAT6 infrastructure, and ample on-site parking.

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    Free-Standing Two-Story Office Building
    Free-Standing Two-Story Office Building

    1089 Augusta Road, Warrenville, SC 29851

    $7,000/Mo
    9,000 sqft

    Well-maintained two-story building with dedicated IT and security, offering immediate space for office, education, or assembly use.

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    Two-Story Office Building with Parking
    Two-Story Office Building with Parking

    1089 Augusta Road, Warrenville, SC 29851

    $7,000/Mo
    9,000 sqft

    Two-story free-standing building with immediately available space, extensive on-site parking, and security plus CAT6 infrastructure.

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    Single-Story Professional Office Building
    Single-Story Professional Office Building

    212 Newberry Street NW, Aiken, SC 29801

    $4,800/Mo
    3,214 sqft

    Single-story office building with five executive offices, conference rooms, and on-site private parking.

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    Pedestrian-Oriented Retail Suites
    Pedestrian-Oriented Retail Suites

    1004 Park View Greer Cir, Greer, SC 29651

    $6,717/Mo
    6,717 sqft

    Retail suites for lease within a pedestrian-friendly downtown district, adjacent to Greer City Park.

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    Professional Office Suite with Private Entry
    Professional Office Suite with Private Entry

    139 Waterloo Street SW, Aiken, SC 29801

    $650/Mo
    134 sqft

    Private office suite in a well-maintained multi-office building with private off-street parking and shared common areas.

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    Adaptable Commercial Space in Anderson
    Adaptable Commercial Space in Anderson

    200 W Benson Street, Anderson, SC 29624

    $7,500/Mo
    12,545 sqft

    Prime commercial property in Anderson's historic district for diverse ventures.

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    Light Industrial Flex Suites
    Light Industrial Flex Suites

    12 Cardinal Rd, Hilton Head Island, SC 29926

    $2,100/Mo
    5,090 sqft

    Two leaseable flex units include warehouse and office space with roll-up and drive-in doors plus dock access and a shared yard.

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    Class A Professional Office Suites
    Class A Professional Office Suites

    4559 Oleander Dr., Myrtle Beach, SC 29577

    $5,006/Mo
    2,225 sqft

    Brand-new Class A office suites offer individual suite entrances and ample parking on Oleander Drive.

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    Retail Storefront Suite with Large Windows
    Retail Storefront Suite with Large Windows

    10080 Ocean Hwy., Pawleys Island, SC 29585

    $2,168/Mo
    1,301 sqft

    1,301 SF storefront retail suite with large windows, an added private room, and restroom, in a retail center on Ocean Highway.

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    Renovated Medical Office Suite
    Renovated Medical Office Suite

    5000 Woodside Executive Ct Unit 5230, Aiken, SC 29803

    $4,810/Mo
    2,540 sqft

    Newly renovated second-floor suite with kitchenette, conference room, six rooms, and private reception and bathroom.

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    Class A Professional Office Suites
    Class A Professional Office Suites

    4559 Oleander Dr., Myrtle Beach, SC 29577

    $5,006/Mo
    2,225 sqft

    Brand-new Class A office suites with individual entrances, brick-and-metal exterior elements, and ample parking in a central Oleander Drive setting.

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    Executive Office Suite with Shared Conference
    Executive Office Suite with Shared Conference

    3955 Highway 17 Bypass, Murrells Inlet, SC 29576

    $525/Mo
    81 sqft

    Executive suite with access to shared conference and break areas, with water, sewer, and electric included.

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    Flex Building with Dock High Doors
    Flex Building with Dock High Doors

    141 Dutchman Boulevard, Irmo, SC 29063

    $12.50 SF/Yr
    7,500 sqft

    Flex building in LI zoning with two dock high doors, fenced loading area, and 10 on-site parking spaces.

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    Retail Boutique with Ample Parking
    Retail Boutique with Ample Parking

    938 Highway 501, Myrtle Beach, SC 29577

    $2,900/Mo
    1,800 sqft

    Currently operating as a retail boutique with good interior condition and ample on-site parking.

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    Medical Office and Wellness Space
    Medical Office and Wellness Space

    2409 Mall Dr, North Charleston, SC 29406

    $8,333/Mo
    8,333 sqft

    Reconfigurable interior with high-ceiling open area and ample free surface parking on a major North Charleston corridor.

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    Private Office Suite in Office Building
    Private Office Suite in Office Building

    139 Waterloo Street SW, Aiken, SC 29801

    $500/Mo
    108 sqft

    Well-maintained multi-office building with shared common areas and private off-street parking for employees and clients.

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    Metal Warehouse with Office
    Metal Warehouse with Office

    7696 Southrail Rd, North Charleston, SC 29420

    $6,800/Mo
    6,800 sqft

    Metal warehouse includes clear-span space with LED lighting, 16' drive-in doors, and office area with private offices and restroom.

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    Office Suite with Conference Room
    Office Suite with Conference Room

    121 Professional Ln., Pawleys Island, SC 29585

    $2,125/Mo
    1,500 sqft

    Leasable office suite with private conference room, kitchen, and restrooms, with ample on-site parking.

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    Single-Story Freestanding Office Building
    Single-Story Freestanding Office Building

    1313A Miller Road, Greenville, SC 29607

    $16.50 SF/Yr
    4,000 sqft

    Functional single-story office layout with multiple private offices, open bullpen space, conference room, and on-site parking.

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    Downtown Professional Office Suite
    Downtown Professional Office Suite

    139 Waterloo Street SW, Aiken, SC 29801

    $500/Mo
    118 sqft

    Private office within a well-maintained multi-office building, with shared common areas and private off-street parking.

    View details

    South Carolina Commercial real estate Market Trends and Statistics

    Explore Commercial real estate leasing options in South Carolina with 3238 listings featured on our commercial real estate exchange. The current inventory includes 7,641,484 square feet of properties with an estimated lease value of $12,644 /Mo.

    Estimated lease rates for Commercial real estate in South Carolina begin at $0.88 SF/Yr, with an average of $28.41 SF/Yr and extend to $533.80 /Mo.
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