Medical Premises

South Carolina Medical Office Space for Sale

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Columbia, SC Greenville, SC Spartanburg, SC Myrtle Beach, SC Charleston, SC Anderson, SC Aiken, SC Rock Hill, SC
221 properties
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Medical Office Building with Exam Rooms
Updated: May 4
Medical Office Building with Exam Rooms

1466 Columbia Highway N, Aiken, SC 29801

$1,200,000
4,044 sqft 0.82 AC lot
4,044‑square‑foot brick medical office built in 2009
0.82‑acre site with approximately 20 parking spaces
Nine fully plumbed exam rooms
Private executive suite with separate entrance and en‑suite full bathroom
Reception area includes a reception window and children’s play area
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Medical Office with Dental Buildout
Updated: May 4
Medical Office with Dental Buildout

1466 Columbia Highway, Aiken, SC 29801

$1,200,000
4,044 sqft 0.82 AC lot
4,044 SF medical office on a 0.82‑acre lot
9 fully plumbed exam rooms
Approximately 20 parking spaces
Private executive suite with separate entrance and en‑suite full bathroom
Built in 2009; brick construction with composition roof
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New Medical Office Space
New Medical Office Space

116 Professional Park Dr., Conway, SC 29526

$1,899,000
3,988 sqft 0.78 AC lot

Purpose-built medical space with exam rooms, private offices, laboratory facilities, and dedicated HVAC for the computer room.

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Two-Story Office Building with Elevator
Two-Story Office Building with Elevator

1044 William Hilton Pkwy, Hilton Head Island, SC 29928

$2,200,000
10,017 sqft

Flexible layout with private offices, training areas, storage, and kitchenette or breakroom spaces.

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Medical Office Building
Medical Office Building

407 N Salem Avenue, Sumter, SC 29150

$795,000
7,337 sqft 1.13 AC lot

Brick medical office with multiple rooms, storage capacity, and public water and sewer service.

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Kershaw Office Building on Large Lot
Kershaw Office Building on Large Lot

104 S Ashe Street, Kershaw, SC 29067

$200,000
1,100 sqft 1.76 AC lot

Office building on 1.76 acres in Kershaw, South Carolina.

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Two-Building Medical Office Park
Two-Building Medical Office Park

710 21st Ave. N, Myrtle Beach, SC 29577

$1,799,000
9,959 sqft 0.16 AC lot

Professional office property configured for medical and office users in Myrtle Beach.

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Medical Office Building with Excess Land
Medical Office Building with Excess Land

8532 Old State Rd, Holly Hill, SC 29059

$1,400,000
6,280 sqft

Medical office property with adjacent excess land for future expansion, parking, or owner-user planning.

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Medical Office with Exam Rooms
Medical Office with Exam Rooms

1706 2nd Loop Rd., Florence, SC 29501

$1,650,000
8,291 sqft 1.34 AC lot

Brick medical facility with exam rooms, administrative offices, covered patient arrival, and dedicated on-site parking.

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Medical Office Building with Expansion Space
Medical Office Building with Expansion Space

430 N Main Street, Sumter, SC 29150

$250,000
2,690 sqft 0.41 AC lot

Configured for clinical, administrative, or training operations with private rooms, reception space, restrooms, and additional buildout capacity.

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Medical Office Building with Exam Rooms
Medical Office Building with Exam Rooms

1466 Columbia Hwy N, Aiken, SC 29801

$1,200,000
4,044 sqft

Brick medical facility with a reception area, executive suite, lab, kitchen, and extensive built-in plumbing.

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Renovated Multi-Tenant Commercial Suite
Renovated Multi-Tenant Commercial Suite

3201 Broad River Road, Columbia, SC 29210

$250,000
1,138 sqft 0.50 AC lot

Renovated in 2014 with multiple tenant suites, including a medical spa and aviation instruction academy.

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Office Building with Reception and Storage
Office Building with Reception and Storage

7193 Saint Andrews Road, Columbia, SC 29212

$699,000
3,500 sqft 0.41 AC lot

Flexible office layout with a welcoming reception area, private offices, conference space, kitchenette, and central air.

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Fully Leased Medical Office Building
Fully Leased Medical Office Building

1665 Herlong Ct, Rock Hill, SC 29732

$1,650,000
6,514 sqft

Office building is fully leased, situated across from Piedmont Medical Center.

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Medical Office Space Under Renovation
Medical Office Space Under Renovation

410 University Parkway, Aiken, SC 29801

$595,000
2,642 sqft 0.06 AC lot

Accessible professional-use property with elevator service and a planned medical education tenancy.

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Single-Level Brick Medical Office
Single-Level Brick Medical Office

203 S Weston Street, Fountain Inn, SC 29644

$1,500,000
0.59 AC lot

C-1 zoning, an included adjacent lot, and a detached brick outbuilding support flexible medical-office use.

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Versatile Commercial Property in Rock Hill
Versatile Commercial Property in Rock Hill

166 Dotson Street, Rock Hill, SC 29732

$1,000,000
10,479 sqft 1.24 AC lot

10,479 SF commercial property suitable for various uses.

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Medical Office Suite Under Renovation
Medical Office Suite Under Renovation

410 University Parkway, Aiken, SC 29801

$595,000
2,642 sqft 0.06 AC lot

Office-zoned medical space with public water, sewer, central air, and flexible professional-use provisions.

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Medical Office Building
Medical Office Building

1250 John B White Sr Boulevard, Spartanburg, SC 29306

$1,295,000
6,875 sqft

Medical office space offered for sale in Spartanburg.

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Renovating Medical Office Space
Renovating Medical Office Space

410 University Parkway, Aiken, SC 29801

$247,500
1,120 sqft 0.03 AC lot

Medical suite undergoing tenant renovations with public water and sewer service.

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Medical Office Building For Sale
Medical Office Building For Sale

102 Buford Avenue, Anderson, SC 29621

$1,050,000
10,405 sqft

Multi-tenant medical office building near AnMed campuses with development potential.

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One-Story Office Building
One-Story Office Building

120 Morgan Street NW, Aiken, SC 29801

$750,000
6,464 sqft 1.71 AC lot

Office property with an auditorium, conference facilities, support offices, and extensive paved parking.

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Renovated Medical Office Building
Renovated Medical Office Building

00 Main St, Barnwell, SC 29812

$300,000
3,495 sqft 0.50 AC lot

Fully renovated office property with 10 offices/rooms, multiple bathrooms, kitchenette, and three separate entrances for flexible use.

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Medical Office Space Under Renovation
Medical Office Space Under Renovation

410 University Parkway, Aiken, SC 29801

$247,500
1,100 sqft 0.03 AC lot

The suite carries Office zoning and is served by public water and public sewer.

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South Carolina Medical Office Space Market Trends and Statistics

Explore 221 medical office space for sale in South Carolina, showcased through 221 active listings on our real estate platform. These investment opportunities span a total of 1,195,916 square feet of properties for sale, with an estimated market value of $57,526,500.

Sale prices for medical spaces in South Carolina start at $150,000, averaging $913,119, and reaching up to $3,150,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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