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    South Carolina Medical Office Space for Sale

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    Columbia, SC Aiken, SC Greenville, SC
    147 results
    Medical Office Building For Sale
    $795,000
    7,337 SF

    Medical Office Building For Sale

    407 N Salem Avenue, Sumter, SC 29150

    Spacious medical office building with multiple rooms and ample storage.

    • Ideal space for a medical practice, offering a ready‑made layout.
    • Large number of rooms and offices, providing flexibility for various uses.
    • Plenty of room for storage, ensuring an organized workspace.
    • Brick and Block Construction, offering durability.
    • Central Air Cooling for year‑round comfort.
    Updated: Jan 27
    View details
    Eastover Commercial Building For Sale
    $399,900
    13,133 SF

    Eastover Commercial Building For Sale

    120 Clarkson Street, Eastover, SC 29044

    Brick building with ample parking, suitable for medical or government.

    • Ample parking available
    • Durable brick building constructed in 2003
    • Includes multiple parcels (TMS R36807‑10‑10 & R311‑01‑05)
    • Features exam rooms and X‑Ray rooms
    • Central heating and air conditioning
    Updated: Mar 23
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    Versatile Professional Office Building
    $250,000
    2,690 SF

    Versatile Professional Office Building

    Spacious office building ideal for various business uses.

    430 N Main Street, Sumter, SC 29150
    View details
    Remodeled Commercial Building Near Downtown
    $340,000
    2,165 SF

    Remodeled Commercial Building Near Downtown

    Turnkey commercial property in prime location with excellent visibility.

    910 W Evans st, Florence, SC 29501
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    Downtown Fountain Inn Commercial Space
    $1,500,000
    0.59 Acres

    Downtown Fountain Inn Commercial Space

    Prime location with potential for various business uses.

    201-203 S Weston Street, Fountain Inn, SC 29644
    View details
    Landrum Medical Building For Sale
    Contact for pricing
    2,400 SF

    Landrum Medical Building For Sale

    2400 SF medical building in downtown Landrum, South Carolina.

    108 W Rutherford Street, Landrum, SC 29356
    View details
    Gaffney Multi-Use High-Visibility Property
    $165,900
    0.33 Acres

    Gaffney Multi-Use High-Visibility Property

    Functional layout suitable for various professional uses or residential conversion.

    403 S Logan Street, Gaffney, SC 29341
    View details
    Westminster Commercial Building for Sale
    $395,000
    0.29 Acres

    Westminster Commercial Building for Sale

    Commercial building suitable for medical or business office use.

    104 W Oak Highway, Westminster, SC 29693
    View details
    Walterboro Commercial Building For Sale
    Contact for pricing

    Walterboro Commercial Building For Sale

    6,000 SF commercial building on 1 acre near I-95.

    1177 Sniders Highway, Walterboro, SC 29488
    View details
    Leased Medical Space For Sale
    $647,111

    Leased Medical Space For Sale

    100% leased medical space with new long-term lease.

    14 Oak Forest Road, Bluffton, SC 29910
    View details
    Leased Medical Space For Sale
    $628,148

    Leased Medical Space For Sale

    100% leased medical space with new 5-year lease.

    14 Oak Forest Road, Bluffton, SC 29910
    View details
    Myrtle Beach Professional Office Park
    $1,799,000
    9,959 SF

    Myrtle Beach Professional Office Park

    Centrally located office park with medical/professional office space.

    710 21st Ave. N, Myrtle Beach, SC 29577
    View details
    Two Professional Buildings Near MUSC
    $975,000
    0.82 Acres

    Two Professional Buildings Near MUSC

    Two professional office buildings near MUSC in Lancaster, South Carolina.

    1201 Colonial Commons Court, Lancaster, SC 29720
    View details
    Aiken Office/Retail Space Available
    $329,900
    2,642 SF

    Aiken Office/Retail Space Available

    Office or retail space in Aiken, South Carolina.

    410 University Parkway unit: Ste 1200, Aiken, SC 29801
    View details
    Move-in Ready Office Space
    $189,900

    Move-in Ready Office Space

    Professional office space in excellent condition near hospital.

    400 N Fant Street, Anderson, SC 29621
    View details
    Aiken Medical Office Building For Sale
    $1,750,000
    9,094 SF

    Aiken Medical Office Building For Sale

    9,000 SF medical office building in Aiken's Southside corridor.

    191 Centre S Boulevard, Aiken, SC 29803
    View details
    Aiken Medical Office Building
    $1,750,000
    9,094 SF

    Aiken Medical Office Building

    Well-maintained medical office building in a thriving Aiken corridor.

    191 Centre S Boulevard, Aiken, SC 29803
    View details
    Leased Medical Space For Sale
    $1,609,481

    Leased Medical Space For Sale

    100% leased medical space with new long-term lease.

    14 Oak Forest Road, Bluffton, SC 29910
    View details
    Wagener Commercial Investment Property
    $239,000
    5,243 SF

    Wagener Commercial Investment Property

    Four-unit commercial property in Wagener, SC, fully leased.

    147-153 Main Street, Wagener, SC 29164
    View details
    Medical Office Near Grand Strand
    $799,888
    3,888 SF

    Medical Office Near Grand Strand

    Spacious two-unit medical office near Grand Strand Medical Center.

    917/919 Medical Circle, Myrtle Beach, SC 29572
    View details
    Charleston Medical Property Investment
    $1,895,000

    Charleston Medical Property Investment

    Thriving medical property in Charleston, SC with favorable lease terms.

    2039 Savannah Highway, Charleston, SC 29407
    View details
    Buildable Medical Office Pad Site
    $90,000
    0.48 Acres

    Buildable Medical Office Pad Site

    Condo-style pad site in established medical park setting.

    110 Buford Avenue lot: 28B, Anderson, SC 29621
    View details
    Versatile Office Building Near Hospital
    $650,000
    8,150 SF

    Versatile Office Building Near Hospital

    8000+ sqft office building ideal for medical or daycare.

    512 Professional Park, Clinton, SC 29325
    View details
    Commercial Lot in Mall Park
    Contact for pricing
    0.15 Acres

    Commercial Lot in Mall Park

    Centrally located commercial lot near shopping, dining, and civic center.

    29 Civic Center Boulevard, Anderson, SC 29625
    View details

    South Carolina Medical Office Space Investment Opportunities Market Analysis

    Explore 147 medical office space for sale in South Carolina, showcased through 147 active listings on our real estate platform. These investment opportunities span a total of 504,449,417 square feet of properties for sale, with an estimated market value of $912,753,700.

    Sale prices for medical spaces in South Carolina start at $50,000, averaging $952,770, and reaching up to $14,525,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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