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    South Carolina Medical Office Space for Sale

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    Columbia, SC Hilton Head Island, SC Greenville, SC Myrtle Beach, SC Spartanburg, SC Aiken, SC Anderson, SC Charleston, SC
    140 properties
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    Mixed-Use Property with Detached ADU
    Updated: Oct 2
    Mixed-Use Property with Detached ADU

    1586 Skylyn Drive, Spartanburg, SC 29307

    $535,000
    2,466 sqft 0.59 AC lot
    0.59‑acre property with an updated brick ranch and detached ADU
    ADU measures 600 square feet and includes 3 bedrooms and 1.5 baths
    Ranch has more than 1,866 square feet of single‑level living space
    Covered carport accommodates two vehicles and includes storage
    Direct access to the Mary Black Rail Trail
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    Medical Office with Dental Buildout
    Updated: May 4
    Medical Office with Dental Buildout

    1466 Columbia Highway, Aiken, SC 29801

    $1,200,000
    4,044 sqft 0.82 AC lot
    4,044 SF medical office on a 0.82‑acre lot
    9 fully plumbed exam rooms
    Approximately 20 parking spaces
    Private executive suite with separate entrance and en‑suite full bathroom
    Built in 2009; brick construction with composition roof
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    Medical Office with Separate Patient Routes
    Medical Office with Separate Patient Routes

    600 Singleton Ridge Rd., Conway, SC 29526

    $1,250,000
    3,114 sqft 0.53 AC lot

    The clinic layout provides distinct paths for patients entering and leaving the building.

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    Medical Office with 9 Exam Rooms
    Medical Office with 9 Exam Rooms

    1466 Columbia Hwy, Aiken, SC 29801

    $1,200,000
    4,044 sqft

    Brick healthcare facility with a covered entry, executive suite, lab, and included FF&E.

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    Medical Campus with Auditorium
    Medical Campus with Auditorium

    1608 Main St., Conway, SC 29526

    $3,950,000
    23,777 sqft 0.77 AC lot

    Two buildings bring together clinical, administrative, and multipurpose areas for medical and professional operations.

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    Medical Office with Exam Rooms
    Medical Office with Exam Rooms

    1466 Columbia Highway N, Aiken, SC 29801

    $1,200,000
    4,044 sqft 0.82 AC lot

    A furnished dental facility includes plumbed treatment rooms and dedicated clinical support areas.

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    New Medical Office Space
    New Medical Office Space

    116 Professional Park Dr., Conway, SC 29526

    $1,899,000
    3,988 sqft 0.78 AC lot

    Purpose-built medical space with exam rooms, private offices, laboratory facilities, and dedicated HVAC for the computer room.

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    Two-Story Office Building with Elevator
    Two-Story Office Building with Elevator

    1044 William Hilton Pkwy, Hilton Head Island, SC 29928

    $2,200,000
    10,017 sqft

    Flexible layout with private offices, training areas, storage, and kitchenette or breakroom spaces.

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    Medical Office With Exam Rooms
    Medical Office With Exam Rooms

    290 Market Street, Ruby, SC 29741

    $175,000
    1,575 sqft 0.30 AC lot

    GC-zoned space includes a multi-room layout with central air conditioning.

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    Medical Office Building
    Medical Office Building

    407 N Salem Avenue, Sumter, SC 29150

    $795,000
    7,337 sqft 1.13 AC lot

    Brick medical office with multiple rooms, storage capacity, and public water and sewer service.

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    Medical Office Building with Excess Land
    Medical Office Building with Excess Land

    8532 Old State Rd, Holly Hill, SC 29059

    $1,400,000
    6,280 sqft

    Medical office property with adjacent excess land for future expansion, parking, or owner-user planning.

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    Medical Office Suite with Private Entry
    Medical Office Suite with Private Entry

    3681 Leaphart Road, West Columbia, SC 29169

    $375,000
    1,700 sqft

    A multi-office layout includes a break room, restrooms, and a small rear outdoor area.

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    Renovated Office Building
    Renovated Office Building

    8311 Two Notch Road, Columbia, SC 29223

    $850,000
    5,969 sqft

    Multiple private entrances support separate business functions or multi-tenant use.

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    Medical Professional Office Building
    Medical Professional Office Building

    710 21st Ave. N, Myrtle Beach, SC 29577

    $1,799,000
    9,959 sqft

    Medical and professional office building with 11 units ranging from 560 to 1,686 SF and 36 on-site parking spaces.

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    Two-Building Medical Office Park
    Two-Building Medical Office Park

    710 21st Ave. N, Myrtle Beach, SC 29577

    $1,799,000
    9,959 sqft 0.16 AC lot

    Professional office property configured for medical and office users in Myrtle Beach.

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    Medical Office with Exam Rooms
    Medical Office with Exam Rooms

    1706 2nd Loop Rd., Florence, SC 29501

    $1,650,000
    8,291 sqft 1.34 AC lot

    Brick medical facility with exam rooms, administrative offices, covered patient arrival, and dedicated on-site parking.

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    Office Redevelopment Opportunity
    Office Redevelopment Opportunity

    3841 Rivers Avenue, North Charleston, SC 29405

    $1,200,000
    5,161 sqft

    Two-building office property with multiple private offices, conference areas, and an X-ray room.

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    Renovated Mixed-Use Property
    Renovated Mixed-Use Property

    3201 Broad River Road, Columbia, SC 29210

    $250,000
    1,138 sqft 0.50 AC lot

    Flexible commercial layout with two suites, on-site parking, and central air conditioning.

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    Historic Mixed-Use Property with Sunroom
    Historic Mixed-Use Property with Sunroom

    1011 W Poinsett Street, Greer, SC 29650

    $685,000
    3,051 sqft

    Distinctive former doctor’s office with period detailing, a detached workshop garage, and flexibility for office, residential, or event use.

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    Medical Office Space Under Renovation
    Medical Office Space Under Renovation

    410 University Parkway, Aiken, SC 29801

    $595,000
    2,642 sqft 0.06 AC lot

    Accessible professional-use property with elevator service and a planned medical education tenancy.

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    Brick Medical Office Space
    Brick Medical Office Space

    116 Professional Park Dr., Conway, SC 29526

    $1,899,000
    3,988 sqft

    Configured for clinical operations with exam rooms, private offices, laboratory, and dedicated computer-room HVAC.

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    Single-Level Brick Medical Office
    Single-Level Brick Medical Office

    203 S Weston Street, Fountain Inn, SC 29644

    $1,500,000
    0.59 AC lot

    C-1 zoning, an included adjacent lot, and a detached brick outbuilding support flexible medical-office use.

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    Medical Office Campus with Auditorium
    Medical Office Campus with Auditorium

    1608 Main St. Unit 1708 Oak St, Conway, SC 29526

    $3,950,000
    23,777 sqft 2.91 AC lot

    Two medical office locations include exam rooms, private offices, pharmacy space, and administrative areas.

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    Medical Office Suite Under Renovation
    Medical Office Suite Under Renovation

    410 University Parkway, Aiken, SC 29801

    $595,000
    2,642 sqft 0.06 AC lot

    Office-zoned medical space with public water, sewer, central air, and flexible professional-use provisions.

    View details
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    South Carolina Medical Office Space Market Trends and Statistics

    Explore 140 medical office space for sale in South Carolina, showcased through 140 active listings on our real estate platform. These investment opportunities span a total of 705,613 square feet of properties for sale, with an estimated market value of $94,855,777.

    Sale prices for medical spaces in South Carolina start at $150,000, averaging $1,171,058, and reaching up to $5,600,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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