Medical Premises

South Carolina Medical Office Space for Sale

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Free-Span Metal Flex Building
Updated: Jul 2
Free-Span Metal Flex Building

313 Commerce Dr., Pawleys Island, SC 29585

$1,200,000
8,812 sqft 1.20 AC lot
8,812 SF free‑span metal commercial building on 1.20 acres at the corner of Commerce Dr and Petigru Dr in Pawleys Island business district
Divided into four separate suites, offering multiple income streams plus room for an owner to occupy part of the property
Three of four suites are leased on month‑to‑month agreements for flexibility to occupy one suite while keeping rental income
Current suite mix includes two professional office suites, a pain management medical practice, and a rear flex suite with warehouse, mezzanine storage, and office space
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313 Commerce Dr., Pawleys Island, SC 29585

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Medical Office Building with Exam Rooms
Updated: Jun 5
Medical Office Building with Exam Rooms

116 Professional Park Dr., Conway, SC 29526

$1,899,000
3,988 sqft 0.78 AC lot
Brand‑new brick construction medical office space available at Singleton Ridge Professional Business Park
Layout includes 9 exam rooms, 3 private offices, and a reception area and lobby
Additional rooms include a medical technician workspace, laboratory room, and computer room with dedicated HVAC
3 bathrooms and on‑site parking for 25 vehicles
Located on Singleton Ridge Road next to Conway Medical Center, Coastal Carolina University, and Horry‑Georgetown Technical College
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Medical Office Building with Parking
Medical Office Building with Parking

1706 2nd Loop Rd., Florence, SC 29501

$1,650,000
8,291 sqft 1.34 AC lot

Turnkey medical office facility featuring 13 exam rooms, X-ray room, and 62 parking spaces.

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Absolute NNN Dental Office
Absolute NNN Dental Office

1173 Ashmore Bridge Rd, Greenville, SC 29605

$4,160,000
4,200 sqft

Newly delivered dental office offered on an Absolute NNN basis with a long-term lease and corporate guarantee.

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Two-Story Professional Office Building
Two-Story Professional Office Building

311 W Home Ave, Hartsville, SC 29550

$799,000
7,759 sqft 0.82 AC lot

Two-story office building with extensive private rooms, conference space, and ample on-site parking.

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Turn-Key Dental Office Building
Turn-Key Dental Office Building

1466 Columbia Highway, Aiken, SC 29801

$1,200,000
4,044 sqft 0.82 AC lot

Turn-key 4,044 SF dental facility with 10 fully plumbed exam rooms and dedicated private suite, plus room for parking.

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Downtown Fountain Inn Commercial Space
Downtown Fountain Inn Commercial Space

203 S Weston Street, Fountain Inn, SC 29644

$1,500,000
4,400 sqft 0.59 AC lot

Prime location with potential for various business uses.

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Chiropractic Office Building
Chiropractic Office Building

518 North Avenue, Rock Hill, SC 29732

$850,000
7,000 sqft

Former chiropractic clinic offering exam and therapy rooms alongside private offices for flexible medical and office use.

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Turn-Key Dental Office in Aiken
Turn-Key Dental Office in Aiken

1466 Columbia Highway N, Aiken, SC 29801

$1,200,000
4,044 sqft 0.82 AC lot

Well-appointed dental office with prime location and included equipment.

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Commercial Office Building
Commercial Office Building

160 Waterloo Street SW, Aiken, SC 29801

$550,000
2,595 sqft 0.27 AC lot

Office building with private offices and open work areas, plus ample on-site parking in downtown Aiken.

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Leased Medical Office Building with Ground Lease
Leased Medical Office Building with Ground Lease

245-1665 Herlong Ct, Rock Hill, SC 29732

$3,020,000
9,572 sqft

Fully leased medical office building with a Truist Bank ground lease, positioned across from a regional medical center.

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Versatile Downtown Commercial Building
Versatile Downtown Commercial Building

404 Calhoun Street, Johnston, SC 29832

$124,900
2,613 sqft 0.06 AC lot

Commercial building with existing plumbing, suited for salon, spa, or multi-water service concepts.

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Medical Office Building
Medical Office Building

407 N Salem Avenue, Sumter, SC 29150

$795,000
7,337 sqft 1.13 AC lot

Tenant-occupied office building with multiple rooms and offices, plus storage space, for medical practice use.

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Versatile Commercial Property in Rock Hill
Versatile Commercial Property in Rock Hill

166 Dotson Street, Rock Hill, SC 29732

$1,000,000
10,479 sqft 1.24 AC lot

10,479 SF commercial property suitable for various uses.

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Professional Office Building with Waiting Area
Professional Office Building with Waiting Area

430 N Main Street, Sumter, SC 29150

$250,000
2,690 sqft 0.41 AC lot

Heated first-floor office space includes waiting, reception, private offices, and exam rooms, plus ample parking for staff and clients.

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Two-Story Office Building
Two-Story Office Building

161 McDonald Ct., Myrtle Beach, SC 29588

$799,900
2,416 sqft 0.28 AC lot

Well-maintained two-story office building with 11 offices, reception and conference space, and parking plus rear storage.

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Flexible Office Building
Flexible Office Building

160 Waterloo St Sw, Aiken, SC 29801

$550,000
2,595 sqft

Office building with private offices and open work areas, plus ample on-site parking for staff and visitors.

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Remodeled Medical Office Building
Remodeled Medical Office Building

910 W Evans st, Florence, SC 29501

$300,000
2,165 sqft 0.27 AC lot

Turnkey, fully rebuilt office suite with treatment-room style spaces, new HVAC, and updated plumbing and electrical.

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Two-Story Office Building
Two-Story Office Building

4702 Oleander Dr., Myrtle Beach, SC 29577

$2,150,000
9,432 sqft 0.70 AC lot

Well-maintained office building with multiple suites, ample parking, and strong accessibility on a central Myrtle Beach corridor.

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Renovated Multi-Tenant Commercial Suite
Renovated Multi-Tenant Commercial Suite

3201 Broad River Road, Columbia, SC 29210

$250,000
1,138 sqft 0.50 AC lot

Renovated in 2014 with multiple tenant suites, including a medical spa and aviation instruction academy.

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Anderson Office Building For Sale
Anderson Office Building For Sale

131 Straight Drive, Anderson, SC 29625

$649,000
4,550 sqft

Well-located office building near Clemson Boulevard and AnMed Medical Center.

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Kershaw Office Building on Large Lot
Kershaw Office Building on Large Lot

104 S Ashe Street, Kershaw, SC 29067

$200,000
1,100 sqft 1.76 AC lot

Office building on 1.76 acres in Kershaw, South Carolina.

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Medical Office Building For Sale
Medical Office Building For Sale

102 Buford Avenue, Anderson, SC 29621

$1,050,000
10,405 sqft

Multi-tenant medical office building near AnMed campuses with development potential.

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Class A Medical Office Suite
Class A Medical Office Suite

4 Okatie Center Boulevard S, Bluffton, SC 29909

$950,000

Ground-floor, ADA-compliant medical office with eight exam rooms, reception area, and substantial storage.

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South Carolina Medical Office Space Market Trends and Statistics

Explore 110 medical office space for sale in South Carolina, showcased through 110 active listings on our real estate platform. These investment opportunities span a total of 728,255 square feet of properties for sale, with an estimated market value of $133,431,057.

Sale prices for medical spaces in South Carolina start at $124,900, averaging $1,588,464, and reaching up to $18,000,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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