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    South Carolina Mixed-use Properties for Sale

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    Columbia, SC Greenville, SC Myrtle Beach, SC Hilton Head Island, SC Spartanburg, SC Aiken, SC Charleston, SC Anderson, SC
    250 properties
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    Mixed-Use Property with Storage
    Updated: Jul 7
    Mixed-Use Property with Storage

    4939 Hwy 321, Gaston, SC 29053

    $1,150,000
    10,775 sqft 1.48 AC lot
    10,775‑square‑foot mixed‑use commercial property on 1.48 acres
    Fully leased property with auto/shop space, storage units, and a U‑Haul operation
    Highway 321 frontage in Gaston with easy access
    Multiple commercial buildings with a newer metal roof
    Overhead bay doors and illuminated roadside sign
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    Leased 4-Unit Mixed-Use Building
    Updated: May 25
    Leased 4-Unit Mixed-Use Building

    2614 E Highway 76, Marion, SC 29571

    $585,000
    7,200 sqft 0.85 AC lot
    Four‑unit office‑retail property is fully leased
    Approximately 7,200+/- SF across adjoining brick and steel‑frame buildings
    0.85‑acre site at 2614 E Highway 76, Marion, SC 29571
    Highway 76 frontage includes a large property sign
    Rear access connects to Sen Gasque Highway
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    Five-Building Mixed-Use Portfolio
    Five-Building Mixed-Use Portfolio

    2725 Cleveland Street, Elloree, SC 29047

    $1,022,000
    13,900 sqft 0.90 AC lot

    Brick improvements with retail, office, mixed-use, and redevelopment flexibility in a South Carolina small-town setting.

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    Mixed-Use Property with Restaurant and Storage
    Mixed-Use Property with Restaurant and Storage

    1411 Cherry Road, Rock Hill, SC 29732

    $1,200,000
    1,800 sqft 0.91 AC lot

    Two-building commercial site combines restaurant space with a concrete block self-storage facility.

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    Renovated Mixed-Use Property
    Renovated Mixed-Use Property

    302 Park Avenue SE, Aiken, SC 29801

    $2,500,000
    8,070 sqft 0.14 AC lot

    Downtown asset combines office, retail, salon, annex, and one-bedroom condominium components.

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    Three-Suite Mixed-Use Property
    Three-Suite Mixed-Use Property

    480 Nelson Blvd., Kingstree, SC 29556

    $600,000
    21,275 sqft 2.10 AC lot

    Commercially zoned property with separate suites suited to office, retail, or multiple business operations.

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    Renovated Mixed-Use Property
    Renovated Mixed-Use Property

    4378 Highway 17 Business, Murrells Inlet, SC 29576

    $1,249,999
    5,078 sqft 0.13 AC lot

    Commercial property combines restaurant, retail, office, and residential configurations within a flexible multi-use layout.

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    Historic Mixed-Use Property
    Historic Mixed-Use Property

    150 Fairfield St SE, Aiken, SC 29801

    $2,500,000
    8,070 sqft

    Renovated downtown building with office, retail, salon, residential, and annex spaces.

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    Live-Work Space with Apartment
    Live-Work Space with Apartment

    Mc Cormick, SC 29835

    $130,000
    1,240 sqft 0.80 AC lot

    Two-level commercial property combines an office with a private apartment and separately metered water and power.

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    Two-Story Day Care Center
    Two-Story Day Care Center

    402 16th Ave. S, Myrtle Beach, SC 29577

    $849,000
    3,400 sqft 0.28 AC lot

    MU-H zoning supports commercial and multifamily-oriented reuse, subject to applicable city requirements and approvals.

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    Mixed-Use Site With Three Buildings
    Mixed-Use Site With Three Buildings

    664 York St NE, Aiken, SC 29801

    $495,000
    7,824 sqft 1.48 AC lot

    GB-zoned property combines office, repair, warehouse, and secured gravel-yard components within the Aiken city limits.

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    Mixed-Use Property with Metal Building
    Mixed-Use Property with Metal Building

    103 Smith St, Greenwood, SC 29649

    $750,000
    7,600 sqft

    Combination of commercial, residential, and office space with additional land for future development, subject to approvals.

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    Mixed-Use Property with Restaurant
    Mixed-Use Property with Restaurant

    6196 Edmund Highway, Lexington, SC 29073

    $799,000
    4,090 sqft 1.65 AC lot

    Two improved structures combine an operating restaurant with functional warehouse space on a commercially zoned site.

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    Mixed-Use Redevelopment Property
    Mixed-Use Redevelopment Property

    114 E. Calhoun Street, Sumter, SC 29150

    $2,500,000
    36,538 sqft 4.25 AC lot

    Former grocery building with substantial acreage and General Commercial zoning.

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    Commercial Kitchen Property with Basement
    Commercial Kitchen Property with Basement

    850 Falling Creek Road, Spartanburg, SC 29301

    $380,000
    1,879 sqft 0.53 AC lot

    Commercial property with an open meeting area, kitchen infrastructure, storage, and parking capacity on a half-acre lot.

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    Historic Wedding Venue With Chapel
    Historic Wedding Venue With Chapel

    208 S Main St, Abbeville, SC 29620

    $490,000
    6,057 sqft 1.20 AC lot

    Three-story estate campus combines event facilities, formal rooms, offices, parking, and accessible restrooms near downtown amenities.

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    Downtown Mixed-Use Property
    Downtown Mixed-Use Property

    117 Asbury Ave, Greenville, SC 29601

    $519,000
    1,732 sqft

    Existing infill building with MX-2 zoning, flexible room layout, hardwood floors, and strong natural light.

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    Brick Mixed-Use Building
    Brick Mixed-Use Building

    25 N Guignard Drive, Sumter, SC 29150

    $550,000
    4,186 sqft 0.32 AC lot

    Flexible commercial space supports office, retail, or barber and beauty uses.

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    Mixed-Use Property with Ice Cream Shop
    Mixed-Use Property with Ice Cream Shop

    612 S Ocean Blvd., Myrtle Beach, SC 29577

    $1,250,000
    2,910 sqft

    Four-bedroom residential space is positioned above an equipped retail operation with the existing ice cream business included.

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    Historic Mixed-Use Property
    Historic Mixed-Use Property

    150 Fairfield Street SE, Aiken, SC 29801

    $2,500,000
    8,070 sqft 0.14 AC lot

    Adaptable downtown asset combining offices, retail suites, a salon, condominium, and detached annex space.

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    Flex Industrial Building
    Flex Industrial Building

    200 Hucks Rd., Aynor, SC 29511

    $1,650,000
    5,000 sqft

    Flexible commercial layout combines office functionality with warehouse space and roll-up loading access.

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    Historic Two-Story Mixed-Use Building
    Historic Two-Story Mixed-Use Building

    108 Park Street NW, Wagener, SC 29164

    $299,900
    2,750 sqft 0.03 AC lot

    Remodeled interior with separate entrances and updated bathrooms on both levels.

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    Mixed-Use Office Property
    Mixed-Use Office Property

    565 Savannah Highway, Charleston, SC 29407

    $1,620,000
    3,018 sqft

    Flexible ground-floor layout with kitchen and mixed-use zoning for business and residential uses.

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    Historic Office Building
    Historic Office Building

    248-260 W Evans st., Florence, SC 29501

    $2,700,000
    16,304 sqft 1.47 AC lot

    Established professional layout with multiple occupants, meeting rooms, reception space, and dedicated parking in downtown Florence.

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    South Carolina Mixed-Use Properties Market Trends and Statistics

    Explore 250 mixed-use properties for sale in South Carolina, showcased through 250 active listings on our real estate platform. These investment opportunities span a total of 1,747,169 square feet of properties for sale, with an estimated market value of $232,898,484.

    Sale prices for multi use buildings in South Carolina start at $69,900, averaging $1,394,601, and reaching up to $16,500,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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