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    South Carolina Mixed-use Properties for Sale

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    Columbia, SC Greenville, SC Spartanburg, SC
    192 results
    Versatile Commercial Property on Edmund Highway
    $799,000
    4,090 SF

    Versatile Commercial Property on Edmund Highway

    6196 Edmund Highway, Lexington, SC 29073

    Commercial property with restaurant and warehouse in Lexington, SC.

    • High‑traffic location on Edmund Highway in Lexington County
    • Two structures: a fully operational restaurant and a warehouse
    • ±1.65‑acre site suitable for investors or owner‑users
    • Warehouse with three overhead door bays for storage or light industrial use
    • Income potential from existing restaurant
    Updated: Apr 30
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    Iconic Downtown Dillon Commercial Property
    $495,000
    24,388 SF

    Iconic Downtown Dillon Commercial Property

    315 E Main Street, Dillon, SC 29536

    Landmark property with showroom, warehouse, and redevelopment potential.

    • Iconic downtown landmark property with exceptional visibility and easy access.
    • Expansive showroom space with large storefront display windows and covered pedestrian frontage.
    • Substantial warehouse capabilities with 3 roll‑up loading doors and rear alley access.
    • Flexible space suitable for retail, mixed‑use redevelopment, office conversion, or other commercial uses.
    • Includes multiple offices, 3 bathrooms, and a kitchen/breakroom area.
    Updated: May 8
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    Iconic Mixed-Use Greenwood Property
    $400,000
    4,753 SF

    Iconic Mixed-Use Greenwood Property

    4,700+ sqft mixed-use property in vibrant Uptown Greenwood.

    204 Main Street, Greenwood, SC 29649
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    Versatile Commercial Flex Property
    $799,900
    6,000 SF

    Versatile Commercial Flex Property

    6,000 sq ft commercial flex property in Greenwood, SC.

    463 Calhoun, Greenwood, SC 29646
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    Versatile Commercial Property in Spartanburg
    $749,000
    2,900 SF

    Versatile Commercial Property in Spartanburg

    Functional space with expansion potential near Downtown Spartanburg.

    449 W Centennial Street, Spartanburg, SC 29303
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    Versatile Commercial Property on Highway
    $325,000
    2,590 SF

    Versatile Commercial Property on Highway

    Commercial property with office, shop, shed, and additional lot.

    3477 Highway 102, Chesterfield, SC 29709
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    Elloree Commercial Portfolio For Sale
    $1,475,000
    13,900 SF

    Elloree Commercial Portfolio For Sale

    Five buildings in Elloree, SC, suitable for retail, office, mixed-use.

    2725 Cleveland Street, Elloree, SC 29047
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    Redevelopment Opportunity in Beaufort, SC
    $2,495,000
    6,500 SF

    Redevelopment Opportunity in Beaufort, SC

    Rare mixed-use redevelopment site with high visibility and trail access.

    12 Neil Road, Beaufort, SC 29906
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    Mixed-Use Site in Beaufort, SC
    $2,250,000
    6,273 SF

    Mixed-Use Site in Beaufort, SC

    Mixed-use site with redevelopment potential in a promising corridor.

    8 Neil Road, Beaufort, SC 29906
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    Multi-Use Property in Easley, SC
    $165,000
    0.34 Acres

    Multi-Use Property in Easley, SC

    Versatile commercial and residential property near downtown Easley.

    612 W Main Street, Easley, SC 29640
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    Versatile Commercial Opportunity in Columbia
    $550,000
    3,960 SF

    Versatile Commercial Opportunity in Columbia

    Prime commercial site with existing structure and redevelopment potential.

    123 Lawand Drive, Columbia, SC 29210
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    Greenville Redevelopment Opportunity
    $449,609
    0.50 Acres

    Greenville Redevelopment Opportunity

    0.5-acre property in Greenville's evolving corridor, ideal for redevelopment.

    730 Wade Hampton Boulevard, Greenville, SC 29609
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    Versatile Commercial Property on 4 Acres
    $235,000
    4,440 SF

    Versatile Commercial Property on 4 Acres

    4-acre commercial property with 4,000+ sq ft metal building.

    4733 Hwy 178 N, Hodges, SC 29653
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    Prime Greenville Commercial Corner Lot
    $1,400,000
    0.72 Acres

    Prime Greenville Commercial Corner Lot

    High-visibility corner lot in vibrant Poinsett District near downtown.

    Poinsett Highway, Greenville, SC 29609
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    Highway 707 Live/Work Opportunity
    $1,800,000
    2,200 SF

    Highway 707 Live/Work Opportunity

    Unique live/work property with income potential on 3.65 acres.

    11091 Highway 707, Murrells Inlet, SC 29576
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    Historic Charleston Mixed-Use Building
    $2,650,000
    4,923 SF

    Historic Charleston Mixed-Use Building

    Three-story mixed-use building in Charleston's historic commercial corridor.

    59 Broad Street, Charleston, SC 29401
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    Historic Edgefield Commercial Opportunity
    $549,000
    6,000 SF

    Historic Edgefield Commercial Opportunity

    Dual income property in historic downtown Edgefield.

    303 Main Street, Edgefield, SC 29824
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    Renovated Commercial Property in Beaufort
    $600,000

    Renovated Commercial Property in Beaufort

    Turnkey investment opportunity in historic Beaufort with high visibility.

    609 Carteret Street, Beaufort, SC 29902
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    Mixed-Use Commercial Property on Highway
    $550,000
    1.07 Acres

    Mixed-Use Commercial Property on Highway

    Mixed-use commercial property on 1.07 acres with highway frontage.

    2821 poinsett Highway, Greenville, SC 29609
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    Aiken Mixed-Use Investment Opportunity
    $575,000
    3,500 SF

    Aiken Mixed-Use Investment Opportunity

    2.8 acres with multiple income-producing properties in Aiken, SC.

    25 Augusta Road, Aiken, SC 29801
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    Historic Coca-Cola Plant Opportunity
    $280,000
    8,000 SF

    Historic Coca-Cola Plant Opportunity

    Historic building with modern potential, suitable for various commercial uses.

    100 Lightsey Street, Hampton, SC 29924
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    Downtown Gaffney Mixed-Use Opportunity
    $210,000
    8,400 SF

    Downtown Gaffney Mixed-Use Opportunity

    8400 SF mixed-use property in Gaffney's Historical District.

    314,316,318 N Limestone Street, Gaffney, SC 29340
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    Renovated Live-Work Space on Acreage
    $389,900
    2,400 SF

    Renovated Live-Work Space on Acreage

    Remodeled live-work space on 1.5 acres, suitable for various uses.

    1715 Cane Branch Rd., Loris, SC 29569
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    Duplex with Detached Garage/Office
    $299,900
    1,612 SF

    Duplex with Detached Garage/Office

    Commercial-zoned duplex with garage/office near downtown Manning.

    48 W Huggins Street, Manning, SC 29102
    View details

    South Carolina Mixed-Use Properties Investment Opportunities Market Analysis

    Explore 2261 mixed-use properties for sale in South Carolina, showcased through 192 active listings on our real estate platform. These investment opportunities span a total of 1,772,117 square feet of properties for sale, with an estimated market value of $185,850,749.

    Sale prices for multi use buildings in South Carolina start at $74,000, averaging $1,644,696, and reaching up to $18,000,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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