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    South Carolina Medical Office Space for Lease

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    124 properties
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    Brand-New Medical Office with Exam Rooms
    Updated: Jun 5
    Brand-New Medical Office with Exam Rooms

    116 Professional Park Dr., Conway, SC 29526

    $10,634/Mo
    3,988 sqft $32 SF/Yr
    Brand‑new brick medical office space available for lease at Singleton Ridge Professional Business Park
    9 exam rooms plus 3 private offices, reception and lobby areas, and a medical technician workspace
    Includes a laboratory room and a dedicated computer room with dedicated HVAC
    3 bathrooms and a laboratory/medical support layout designed for clinical use
    25 on‑site parking spaces
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    Class A Medical Office Suite Renovated
    Updated: Jun 18
    Class A Medical Office Suite Renovated

    4310 Highway 17 Business, Murrells Inlet, SC 29576

    $8,000/Mo
    3,557 sqft $26.99 SF/Yr
    Suite 103 offers 3,557 SF of Class A medical office space in a healthcare facility in Murrells Inlet, SC
    Tenant Improvement Allowance available for medical users to customize the space for clinical and operational needs
    Utilities, trash service, and janitorial service included in the rent
    Recently renovated building with dedicated patient and service elevators and a shared lobby with a complimentary coffee and beverage station
    Cosatron air purification system and Sentry 30 security system, plus an automatic water shut‑off system after business hours
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    Renovated Fully Furnished Office Building
    Renovated Fully Furnished Office Building

    792 John B White Sr Boulevard, Spartanburg, SC 29306

    $2,808/Mo

    Move-in ready office building with updated finishes and full furnishings, positioned for convenient regional access via major interstates.

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    Build-to-Suit Office Suite
    Build-to-Suit Office Suite

    148 Waterloo Street SW, Aiken, SC 29801

    $3,772/Mo
    1,886 sqft $24 SF/Yr

    Cold-and-dark office space offered with options for tenant-led buildout for general or medical use.

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    Aiken Office/Medical Space Available
    Aiken Office/Medical Space Available

    5000 Woodside Executive Court, Aiken, SC 29803

    $4,810/Mo
    2,540 sqft $22.72 SF/Yr

    Office and medical suites available in a professional Aiken complex.

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    Aiken Office Space for Rent
    Aiken Office Space for Rent

    5000 Woodside Executive Court, Aiken, SC 29803

    $4,810/Mo
    2,540 sqft $22.72 SF/Yr

    Renovated office space suitable for medical or administrative uses.

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    First-Floor Office Suite with Conference
    First-Floor Office Suite with Conference

    2315 N Main Street, Anderson, SC 29621

    $650/Mo

    First-floor private suite in a two-story, all-brick Class A office building with shared kitchenette and conference room.

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    First-Floor Medical/Professional Suite
    First-Floor Medical/Professional Suite

    2315 N Main Street, Anderson, SC 29621

    $500/Mo

    First-floor private office suite with shared kitchenette and conference room in a two-story brick building.

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    Medical Office and Wellness Space
    Medical Office and Wellness Space

    2409 Mall Dr, North Charleston, SC 29406

    $8,333/Mo
    8,333 sqft $12 SF/Yr

    Reconfigurable interior with high-ceiling open area and ample free surface parking on a major North Charleston corridor.

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    Multi-Tenant Office Suite
    Multi-Tenant Office Suite

    1510 Whiskey Road, Aiken, SC 29803

    $18 SF/Yr
    1,775 sqft $2,662/Mo

    Office suite for lease on Whiskey Road with a second-floor break room included.

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    Turnkey Medical Office Suites
    Turnkey Medical Office Suites

    4100 N. Main Street, Columbia, SC 29203

    $20 SF/Yr
    3,742 sqft $6,236/Mo

    Turnkey suites with exam rooms and plumbing, recently renovated common areas, designed for efficient medical operations.

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    Office Suites with Highway Frontage
    Office Suites with Highway Frontage

    2 Westbury Park Way, Bluffton, SC 29910

    $30 SF/Yr
    3,870 sqft $9,675/Mo

    Two office suites are available with extensive Hwy 278 frontage and ample on-site parking for employees and visitors.

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    Medical Office Suite with Reception
    Medical Office Suite with Reception

    30 Memorial Medical Dr, Greenville, SC 29605

    $18 SF/Yr
    2,336 sqft $3,504/Mo

    New LVP flooring supports a patient-ready layout with reception, private offices, and accessible restrooms.

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    First-Floor Office Suite
    First-Floor Office Suite

    2315 N Main Street, Anderson, SC 29621

    $3,400/Mo

    First-floor suite with 8 private offices, kitchen, and conference room in a Class A, all-brick building.

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    Single-Story Office Building
    Single-Story Office Building

    255 East Bay Street, Charleston, SC 29401

    $35 SF/Yr
    4,730 sqft $13,795/Mo

    Centrally located office building with flexible lease terms and included parking to support medical or professional users.

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    Premier Medical Office Space Available
    Premier Medical Office Space Available

    1650 Skylyn Drive, Spartanburg, SC 29307

    $20 SF/Yr
    7,039 sqft $11,731/Mo

    Class A medical office space in Spartanburg's prime location.

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    Class A Medical Office Building
    Class A Medical Office Building

    1200 Innovation Way, Mount Pleasant, SC 29466

    $28 SF/Yr
    14,084 sqft $32,862/Mo

    Renovated medical/office building with ample parking in Mt. Pleasant.

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    West Columbia Office/Medical Suite
    West Columbia Office/Medical Suite

    3618 Sunset Blvd., West Columbia, SC 29169

    $18 SF/Yr
    12,000 sqft $18,000/Mo

    Office/medical suite for lease near Lexington Medical Hospital.

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    Spacious Office and Medical Suite
    Spacious Office and Medical Suite

    345 Patricia Lane, Fort Mill, SC 29708

    $29.50 SF/Yr
    8,988 sqft $22,095/Mo

    8,988 SF professional office/medical suite in Fort Mill, SC.

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    Moncks Corner Medical Office Sublease
    Moncks Corner Medical Office Sublease

    422 Drive In Lane, Moncks Corner, SC 29461

    $22 SF/Yr
    7,490 sqft $13,731/Mo

    Class A medical office building for sublease in Moncks Corner.

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    Seneca Office Space For Lease
    Seneca Office Space For Lease

    865 Old Clemson Highway, Seneca, SC 29678

    $1,500/Mo

    Two-level office building suitable for various businesses, near Clemson.

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    Rock Hill Medical/Office Suites
    Rock Hill Medical/Office Suites

    420 S Herlong Ave, Rock Hill, SC 29732

    $18 SF/Yr
    2,100 sqft $3,150/Mo

    Medical/office suites in established Rock Hill medical complex for rent.

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    Medical Office Space For Rent
    Medical Office Space For Rent

    105 Ben Casey Dr, Fort Mill, SC 29708

    $30 SF/Yr
    2,330 sqft $5,825/Mo

    Medical office space in established park, convenient location.

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    Medical/Office Space in Rock Hill
    Medical/Office Space in Rock Hill

    410 S Herlong Ave, Rock Hill, SC 29732

    $18 SF/Yr
    2,598 sqft $3,897/Mo

    Established medical complex with adaptable suites near key locations.

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    South Carolina Medical Office Space Market Trends and Statistics

    Explore Medical Office Space leasing options in South Carolina with 124 listings featured on our commercial real estate exchange. The current inventory includes 747,679 square feet of properties with an estimated lease value of $1,644 /Mo.

    Estimated lease rates for Medical Office Space in South Carolina begin at $8 SF/Yr, with an average of $24.19 SF/Yr and extend to $40 SF/Yr.
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