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    South Carolina Medical Office Space for Lease

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    Greenville, SC Columbia, SC Charleston, SC
    128 results
    Lady's Island Versatile Office Space
    $3,600/Mo
    1,500 SF

    Lady's Island Versatile Office Space

    27 Kemmerlin Lane, Beaufort, SC 29907

    Well-conditioned office space ideal for medical, wellness, or traditional office.

    • Versatile 1,500 SF office space suitable for medical, wellness, salon, or traditional office use.
    • 7 treatment rooms with plumbing stubbed and capped.
    • Located in Kemmerlin Business Park with noteworthy businesses and organizations.
    • Newly renovated lobby, two ADA restrooms, and kitchenette.
    • Front and rear covered patios and ~15 shared parking spaces.
    Updated: Feb 24
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    Professional Office Space Available
    $3,670/Mo
    1,000 SF

    Professional Office Space Available

    5187 Horry Dr., Murrells Inlet, SC 29576

    Professional office space for lease in Murrells Inlet, SC.

    • Excellent location in the heart of Murrells Inlet with convenient access to Highway 17 Business and Bypass.
    • Divisible space: 3,000 SF total available, can be leased as a single space or divided into 1,000 SF and 2,000 SF suites.
    • 2,000 SF suite features a reception area, conference room, and multiple executive offices with nicely appointed finishes.
    • Tenant Improvement (TI) Allowance available for customization and upfit.
    • Ample on‑site parking and monument signage available for each unit.
    Updated: Mar 27
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    Aiken Office Space For Lease
    $3,772/Mo
    1,886 SF

    Aiken Office Space For Lease

    New build-out opportunity for office or medical space in Aiken.

    148 Waterloo Street SW, Aiken, SC 29801
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    Aiken Office/Medical Space Available
    $4,810/Mo
    2,540 SF

    Aiken Office/Medical Space Available

    Office and medical suites available in a professional Aiken complex.

    5000 Woodside Executive Court, Aiken, SC 29803
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    Aiken Office Space for Rent
    $4,810/Mo
    2,540 SF

    Aiken Office Space for Rent

    Renovated office space suitable for medical or administrative uses.

    5000 Woodside Executive Court, Aiken, SC 29803
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    Class A Office Space
    $3,400/Mo

    Class A Office Space

    Professional office suite for rent in Anderson, SC.

    2315 N Main Street, Anderson, SC 29621
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    Murrells Inlet Office/Retail/Medical Space
    $1,458/Mo
    1,250 SF

    Murrells Inlet Office/Retail/Medical Space

    Multi-tenant building with office/retail/medical space for lease.

    637 Bellamy Ave., Murrells Inlet, SC 29576
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    Versatile Commercial Space on Lady's Island
    $3,800/Mo
    2,250 SF

    Versatile Commercial Space on Lady's Island

    Two-story commercial building with flexible space for rent.

    8 Celadon Drive, Beaufort, SC 29907
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    Prime Commercial Space in Beaufort
    $3,000/Mo

    Prime Commercial Space in Beaufort

    Highly visible commercial space suitable for various business types.

    3 Celadon Drive, Beaufort, SC 29907
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    Pawleys Island Professional Office Space
    $3,632/Mo
    1,981 SF

    Pawleys Island Professional Office Space

    Versatile office space in high-visibility Pawleys Island location.

    38 Blackgum Rd., Pawleys Island, SC 29585
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    West Ashley Office Space Available
    $24 SF/Yr
    2,652 SF

    West Ashley Office Space Available

    Office spaces for lease in central West Ashley location.

    1064 Gardner Road, Charleston, SC 29407
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    Premier Medical Office Space Available
    $20 SF/Yr
    7,039 SF

    Premier Medical Office Space Available

    Class A medical office space in Spartanburg's prime location.

    1650 Skylyn Drive, Spartanburg, SC 29307
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    Turn-Key Medical Office Space
    $22 SF/Yr
    8,300 SF

    Turn-Key Medical Office Space

    8,300 SF medical office in Surfside Beach, South Carolina.

    1945 Glenns Bay Road, Surfside Beach, SC 29575
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    Two-Story Office Building For Rent
    $16 SF/Yr
    3,960 SF

    Two-Story Office Building For Rent

    Two-story office building with flexible layout in central Columbia.

    123 Lawand Dr, Columbia, SC 29210
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    West Columbia Office/Medical Suite
    $18 SF/Yr
    12,000 SF

    West Columbia Office/Medical Suite

    Office/medical suite for lease near Lexington Medical Hospital.

    3618 Sunset Blvd., West Columbia, SC 29169
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    Spacious Office and Medical Suite
    $29 SF/Yr
    8,988 SF

    Spacious Office and Medical Suite

    8,988 SF professional office/medical suite in Fort Mill, SC.

    345 Patricia Lane, Fort Mill, SC 29708
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    Medical Office Space For Lease
    $20 SF/Yr
    7,659 SF

    Medical Office Space For Lease

    Medical office space in prime healthcare corridor location.

    161 Medical Circle, West Columbia, SC 29169
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    Rock Hill Medical/Office Suites
    $18 SF/Yr
    2,100 SF

    Rock Hill Medical/Office Suites

    Medical/office suites in established Rock Hill medical complex for rent.

    420 S Herlong Ave, Rock Hill, SC 29732
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    Medical Office Space For Rent
    $30 SF/Yr
    2,330 SF

    Medical Office Space For Rent

    Medical office space in established park, convenient location.

    105 Ben Casey Dr, Fort Mill, SC 29708
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    Medical/Office Space in Rock Hill
    $18 SF/Yr
    2,598 SF

    Medical/Office Space in Rock Hill

    Established medical complex with adaptable suites near key locations.

    410 S Herlong Ave, Rock Hill, SC 29732
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    Class A Medical Office Building
    $28 SF/Yr
    14,084 SF

    Class A Medical Office Building

    Renovated medical/office building with ample parking in Mt. Pleasant.

    1200 Innovation Way, Mount Pleasant, SC 29466
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    Seneca Office Space For Lease
    $1,500/Mo

    Seneca Office Space For Lease

    Two-level office building suitable for various businesses, near Clemson.

    865 Old Clemson Highway, Seneca, SC 29678
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    North Charleston Office Space Available
    $19 SF/Yr
    1,664 SF

    North Charleston Office Space Available

    Office space for rent in North Rivers Business Center.

    2070 Northbrook Blvd, North Charleston, SC
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    Medical Office in Mt. Pleasant
    $34 SF/Yr
    60,809 SF

    Medical Office in Mt. Pleasant

    Medical office space available for sublease in Mt. Pleasant.

    1300 Hospital Dr, Mount Pleasant, SC 29464
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    South Carolina Medical Office Space Leasing Opportunities Market Analysis

    Explore Medical Office Space leasing options in South Carolina with 128 listings featured on our commercial real estate exchange. The current inventory includes 814,061 square feet of properties with an estimated lease value of $1,700 /Mo.

    Estimated lease rates for Medical Office Space in South Carolina begin at $10 SF/Yr, with an average of $23 SF/Yr and extend to $44 SF/Yr.
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