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    South Carolina Medical Office Space for Lease

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    Columbia, SC Greenville, SC Charleston, SC North Charleston, SC Spartanburg, SC Rock Hill, SC Myrtle Beach, SC Summerville, SC
    167 properties
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    Medical Office Space with Storage
    Updated: Jul 31
    Medical Office Space with Storage

    407 N Salem Avenue, Sumter, SC 29150

    $7,337/Mo
    7,337 sqft
    1.13‑acre lot with 7,337 square feet of medical office space
    Brick and block construction
    Large number of rooms and offices with plenty of storage room
    Central air plus heat pump heating
    Tile and carpet flooring
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    Class A Medical Office Suite
    Updated: Jun 18
    Class A Medical Office Suite

    4310 Highway 17 Business, Murrells Inlet, SC 29576

    $8,000/Mo
    3,557 sqft 3.00 AC lot
    3,557 square feet in Suite 103
    Recently renovated Class A medical office space
    Approximately 160 parking spaces with monument signage opportunities
    Utilities, trash service, and janitorial service included in the rent
    Sentry 30 Security System and automatic after‑hours water shut‑off
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    Class A Professional Office Suites
    Class A Professional Office Suites

    4559 Oleander Dr., Myrtle Beach, SC 29577

    $5,006/Mo
    2,225 sqft 0.85 AC lot

    Brand-new Class A professional office suites in Myrtle Beach offer individual suite entrances, prominent signage opportunities, and ample parking.

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    Renovated Medical Office Suite
    Renovated Medical Office Suite

    5000 Woodside Executive Ct Unit 5230, Aiken, SC 29803

    $4,810/Mo
    2,540 sqft 8.00 AC lot

    Newly renovated second-floor suite with kitchenette, conference room, six rooms, and private reception and bathroom.

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    Office Suite with Conference Room
    Office Suite with Conference Room

    121 Professional Ln., Pawleys Island, SC 29585

    $2,125/Mo
    1,500 sqft 1.00 AC lot

    Professional workspace includes a dedicated meeting room, kitchen area, modern restroom, natural light, and easy US-17 access.

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    New Medical Office Space
    New Medical Office Space

    116 Professional Park Dr., Conway, SC 29526

    $10,634/Mo
    3,988 sqft 0.78 AC lot

    Purpose-built medical workspace with exam, administrative, laboratory, and reception areas.

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    Second-Floor Office Suite with Kitchenette
    Second-Floor Office Suite with Kitchenette

    5000 Woodside Executive Court, Aiken, SC 29803

    $4,810/Mo
    2,540 sqft

    Newly renovated second-floor suite with kitchenette, reception, private offices, and accessible elevator access.

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    Medical Office and Wellness Space
    Medical Office and Wellness Space

    2409 Mall Dr, North Charleston, SC 29406

    $8,333/Mo
    8,333 sqft 1.21 AC lot

    Reconfigurable interior with high-ceiling open area and ample free surface parking on a major North Charleston corridor.

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    Renovated Office Suite
    Renovated Office Suite

    5000 Woodside Executive Court, Aiken, SC 29803

    $4,810/Mo
    2,540 sqft 5.36 AC lot

    Second-floor space includes a kitchenette, reception area, conference room, storage, and six office or treatment rooms.

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    Build-to-Suit Office Suite
    Build-to-Suit Office Suite

    148 Waterloo Street SW, Aiken, SC 29801

    $3,772/Mo
    1,886 sqft

    Cold-and-dark office space offered with options for tenant-led buildout for general or medical use.

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    Class A Medical Office Building
    Class A Medical Office Building

    1280 Hospital Dr, Mt Pleasant, SC 29464

    $2,582/Mo
    2,582 sqft

    Class A medical office building offers a covered patient entry and abundant surface parking.

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    Medical Office Suite with Private Offices
    Medical Office Suite with Private Offices

    1264 Ribaut Road, Beaufort, SC 29902

    $2,845/Mo
    0.01 AC lot

    Open work area, data room, shower, and existing plumbing support varied professional uses.

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    Multi-Tenant Office Suite
    Multi-Tenant Office Suite

    1510 Whiskey Road, Aiken, SC 29803

    $18 SF/Yr
    1,775 sqft

    Office suite for lease on Whiskey Road with a second-floor break room included.

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    Renovating Office Park Suites
    Renovating Office Park Suites

    15 Gamecock Ave, Charleston, SC 29407

    $2,500/Mo
    3,625 sqft

    Two office suites are available within Orange Grove Office Park with ongoing renovations and quick access to I-26.

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    Furnished Medical Office Suite
    Furnished Medical Office Suite

    125 Co-Op Rd., Myrtle Beach, SC 29588

    $4,025/Mo
    1,610 sqft 0.69 AC lot

    Configured with exam rooms, reception, conference, and private office areas.

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    Build-to-Suit Office Suite
    Build-to-Suit Office Suite

    148 Waterloo Street Sw Suite 5, Aiken, SC 29801

    $3,772/Mo
    1,886 sqft

    Cold and dark suite offers 1,886 sf for buildout as general or medical office space in a multi-tenant building.

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    Medical Office Suites with Ample Parking
    Medical Office Suites with Ample Parking

    1300 Hospital Dr, Mt Pleasant, SC 29464

    $1,757/Mo
    3,425 sqft

    Three-story medical office building offers suites for lease with ample on-site paved parking.

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    Medical Office Suite with Reception
    Medical Office Suite with Reception

    9000 Bowen Pier Dr, Hanahan, SC 29410

    $1,787/Mo
    1,900 sqft

    Medical suite includes a reception area, admin office, four private offices or treatment rooms, and a storage closet.

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    Office Suites with Highway Frontage
    Office Suites with Highway Frontage

    2 Westbury Park Way, Bluffton, SC 29910

    $32 SF/Yr
    3,870 sqft

    Two office suites are available with extensive Hwy 278 frontage and ample on-site parking for employees and visitors.

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    Retail-Ready Office Suite
    Retail-Ready Office Suite

    773 Main St, North Myrtle Beach, SC 29582

    $2,059/Mo
    1,300 sqft

    Professionally built-out suite with three private offices, reception, and conference area at Ocean Plaza Shopping Center.

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    Turnkey Medical Office Suites
    Turnkey Medical Office Suites

    4100 N. Main Street, Columbia, SC 29203

    $20 SF/Yr
    3,742 sqft

    Turnkey suites with exam rooms and plumbing, recently renovated common areas, designed for efficient medical operations.

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    Mount Pleasant Retail/Office/Medical Space
    Mount Pleasant Retail/Office/Medical Space

    1123 Queensborough Boulevard, Mount Pleasant, SC 29464

    $30 SF/Yr
    3,949 sqft

    3,949 SF space ideal for retail, office, or medical.

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    Two-Building Office Medical Park
    Two-Building Office Medical Park

    3600 Forest Dr, Columbia, SC 29204

    $22 SF/Yr
    150,000 sqft

    Two office and medical buildings offer extensive parking and planned upgrades to common areas and facades.

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    Single-Story Office Building
    Single-Story Office Building

    255 East Bay Street, Charleston, SC 29401

    $35 SF/Yr
    4,730 sqft

    Centrally located office building with flexible lease terms and included parking to support medical or professional users.

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    South Carolina Medical Office Space Market Trends and Statistics

    Explore Medical Office Space leasing options in South Carolina with 167 listings featured on our commercial real estate exchange. The current inventory includes 1,493,987 square feet of properties with an estimated lease value of $815.34.

    Estimated lease rates for Medical Office Space in South Carolina begin at $6.16 SF/Yr, with an average of $22.04 SF/Yr and extend to $35 SF/Yr.
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