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    South Carolina Office Spaces for Lease

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    998 properties
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    Two-Story Professional Office Suites
    Two-Story Professional Office Suites

    101, Ladys Island, SC 29907

    $1,300/Mo

    Available private-office suites with exterior windows and entrances in an ADA-compliant, two-story building with fiber and parking.

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    Medical Office Space For Lease
    Medical Office Space For Lease

    161 Medical Circle, West Columbia, SC 29169

    $20 SF/Yr
    7,659 sqft

    Medical office space in prime healthcare corridor location.

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    Main Street Professional Office Spaces
    Main Street Professional Office Spaces

    200 North Main Street, Greenville, SC 29601

    $550/Mo
    900 sqft

    Newly renovated office spaces with Main Street views for lease.

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    Rock Hill Coworking Space Available
    Rock Hill Coworking Space Available

    116 E Main St, Suite 201, Rock Hill, SC 29730

    $200 SF/Yr
    12,460 sqft

    Flexible coworking and dedicated desk space in vibrant Knowledge Park.

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    Spartanburg Flex Building For Lease
    Spartanburg Flex Building For Lease

    440 Southport Commerce Blvd, Spartanburg, SC 29306

    $12 SF/Yr
    6,800 sqft

    Flex building with office and outdoor storage in Spartanburg.

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    Office Suite in West Columbia
    Office Suite in West Columbia

    1523 Sunset Blvd., West Columbia, SC 29169

    $15 SF/Yr
    9,890 sqft

    Office suite for lease near downtown Columbia and Lexington Medical Center.

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    Class A Office Space
    Class A Office Space

    177 Meeting Street, Charleston, SC 29401

    $42 SF/Yr
    22,062 sqft

    Prime office building in the heart of Historic Charleston.

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    Mount Pleasant Retail/Office/Medical Space
    Mount Pleasant Retail/Office/Medical Space

    1123 Queensborough Boulevard, Mount Pleasant, SC 29464

    $30 SF/Yr
    3,949 sqft

    3,949 SF space ideal for retail, office, or medical.

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    Rock Hill Office Suite Available
    Rock Hill Office Suite Available

    1674 Cranium Dr, Suite 102, Rock Hill, SC 29732

    $19 SF/Yr
    1,919 sqft

    Professional office suite with reception, offices, conference room, and breakroom.

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    Office Space Near Downtown Anderson
    Office Space Near Downtown Anderson

    1214 North Main Street, Anderson, SC 29621

    $1,200/Mo
    900 sqft

    Office suite with three private offices, reception, and kitchenette.

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    Downtown Columbia Office Space Available
    Downtown Columbia Office Space Available

    1333 Main Street, Columbia, SC 29201

    $21.75 SF/Yr
    17,594 sqft

    Prime office space for rent in downtown Columbia.

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    Office and Medical Suites Available
    Office and Medical Suites Available

    3618 Ashley Phosphate Road, Charleston, SC 29418

    $650/Mo
    309 sqft

    Two-story building with executive and medical suites for lease.

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    Class A Office Space Available
    Class A Office Space Available

    1430 48th Avenue North, Myrtle Beach, SC 29577

    $30 SF/Yr
    20,000 sqft

    Class A office building with customizable floor plans for rent.

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    Columbia Office Building For Lease
    Columbia Office Building For Lease

    1628 Browning Road, Columbia, SC 29210

    $15.75 SF/Yr
    16,966 sqft

    Class B office space with interstate visibility and modern amenities.

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    Single Tenant Office Space
    Single Tenant Office Space

    9 Rue Du Bois, Beaufort, SC 29907

    $80 SF/Yr
    90 sqft

    Office space available for single tenant occupancy.

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    Office Space Near Government Buildings
    Office Space Near Government Buildings

    3844 Leeds Ave, North Charleston, SC 29405

    $2,000/Mo
    1,244 sqft

    Office space with high visibility and convenient highway access.

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    Class A Office Space Available
    Class A Office Space Available

    1400 Browning Road, Columbia, SC 29210

    $20.75 SF/Yr
    35,838 sqft

    Premium office building with high-tech infrastructure and convenient access.

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    Class A Executive Office Suite
    Class A Executive Office Suite

    3425 Maybank Hwy, Johns Island, SC 29455

    Contact for pricing
    1,776 sqft

    Well-appointed Class A executive suite within a landscaped office park, offering shared conference and reception amenities.

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    Prime Commercial Site in Port Royal
    Prime Commercial Site in Port Royal

    1670 Ribaut Road, Port Royal, SC 29935

    $6,000/Mo

    High-visibility commercial site ideal for retail, professional, and food businesses.

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    Office Property Near Downtown Columbia
    Office Property Near Downtown Columbia

    720 Gracern Rd, Columbia, SC

    $17.50 SF/Yr
    8,181 sqft

    Office and flex spaces available near I-20 and I-26.

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    Open Layout Office Studio
    Open Layout Office Studio

    1715 Hollydale Ct, Johns Island, SC 29455

    Contact for pricing
    2,000 sqft

    Flexible open-plan suite formerly used as an indoor fitness studio, well-suited for a range of general office uses.

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    Premier Office Complex in Columbia
    Premier Office Complex in Columbia

    300 Arbor Lake Drive, Columbia, SC 29223

    $12.50 SF/Yr
    20,733 sqft

    Centrally located office complex with amenities and interstate visibility.

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    Class A Office Space
    Class A Office Space

    4390 Belle Oaks Drive, North Charleston, SC 29405

    $27 SF/Yr
    45,644 sqft

    Class A office building with convenient highway access.

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    Medical Office Suite
    Medical Office Suite

    3210 Landmark Drive, North Charleston, SC 29418

    Contact for pricing
    1,880 sqft

    Move-in ready OB-GYN medical space with strong visibility, signage, and ample parking for healthcare practices.

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