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    Beaufort County, SC Medical Office Space for Lease

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    Greenville, SC Columbia, SC Charleston, SC
    9 results
    Lady's Island Versatile Office Space
    $3,600/Mo
    1,500 SF

    Lady's Island Versatile Office Space

    27 Kemmerlin Lane, Beaufort, SC 29907

    Well-conditioned office space ideal for medical, wellness, or traditional office.

    • Versatile 1,500 SF office space suitable for medical, wellness, salon, or traditional office use.
    • 7 treatment rooms with plumbing stubbed and capped.
    • Located in Kemmerlin Business Park with noteworthy businesses and organizations.
    • Newly renovated lobby, two ADA restrooms, and kitchenette.
    • Front and rear covered patios and ~15 shared parking spaces.
    Updated: Feb 24
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    Versatile Commercial Space on Lady's Island
    $3,800/Mo
    2,250 SF

    Versatile Commercial Space on Lady's Island

    8 Celadon Drive, Beaufort, SC 29907

    Two-story commercial building with flexible space for rent.

    • High‑visibility location at the corner of Sam's Point Road, ideal for establishing a brand.
    • Modified Gross Lease at $4,000/month includes HOA, property taxes, building insurance, water, and trash collection.
    • Versatile two‑story building with 2250 sq ft of professional space, suitable for various businesses.
    • Ground floor (approx 1150 sq ft) features an open floor plan, polished concrete floors, high‑end finishes, dedicated entrance, and modern restroom.
    • Upper floor (approx 1100 sq ft) includes a mix of wood flooring and multiple existing rooms/offices, a separate private entrance, and a kitchenette.
    Updated: Nov 1, 2025
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    Prime Commercial Space in Beaufort
    $3,000/Mo

    Prime Commercial Space in Beaufort

    Highly visible commercial space suitable for various business types.

    3 Celadon Drive, Beaufort, SC 29907
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    Medical Suites in Hilton Head
    Contact for pricing

    Medical Suites in Hilton Head

    Medical office suites for lease in prestigious medical complex.

    Hilton Head Island, SC 29926
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    Highway 170 Retail/Office/Medical Space
    $36 SF/Yr

    Highway 170 Retail/Office/Medical Space

    Retail, office, or medical space for lease on Highway 170.

    48 Terrace Drive, Okatie, SC 29909
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    Medical Building on Hilton Head
    $22 SF/Yr

    Medical Building on Hilton Head

    Stand-alone medical building for lease on Hilton Head Island.

    4101 Main St, Suite E & F, Hilton Head Island, SC 29926
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    North End Hilton Head Offices
    $22 SF/Yr

    North End Hilton Head Offices

    Professional office/medical spaces for lease on Hilton Head Island.

    100 Exchange Street, Hilton Head Island, SC 29926
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    Bluffton Retail/Office/Medical Building
    $35 SF/Yr

    Bluffton Retail/Office/Medical Building

    Pre-leasing single-story retail/office/medical building in the heart of Bluffton.

    128 Bluffton Road, 29910, SC, Bluffton, SC 29910
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    Bluffton Office/Medical Suites Available
    $32 SF/Yr
    3,870 SF

    Bluffton Office/Medical Suites Available

    Class A office and medical suites for rent in Bluffton.

    2 WESTBURY PKWY, Bluffton, SC
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    Based on your search, we've compiled 29 Potential Opportunities for your consideration. Besides 9 Active listings in Beaufort County, SC, we suggest exploring alternatives. Similar 16 Properties for Sales.

    Similar Spaces for Sale in Beaufort County, SC

    Consider Similar Space for Sale. We found 16 Spaces matching your search parameters.

    Leased Medical Space For Sale
    $647,111
    Leased Medical Space For Sale

    100% leased medical space with new long-term lease.

    14 Oak Forest Road, Bluffton, SC 29910

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    Leased Medical Space For Sale
    $628,148
    Leased Medical Space For Sale

    100% leased medical space with new long-term lease.

    14 Oak Forest Road, Bluffton, SC 29910

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    Leased Medical Space For Sale
    $1,609,481
    Leased Medical Space For Sale

    100% leased medical space with new long-term lease.

    14 Oak Forest Road, Bluffton, SC 29910

    View details
    Professional Office Condo with Income
    $769,000
    Professional Office Condo with Income

    Multi-suite office condo with existing rental income in prime location.

    70 Main Street, Suite 400 |, Hilton Head Island, SC 29926

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    Hilton Head Office/Medical Space
    $375,000
    Hilton Head Office/Medical Space

    Office/Medical space for sale near Hilton Head Hospital.

    23 Main Street, Suite 303, Hilton Head Island, SC 29926

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    Two-Story Office Building For Sale
    $2,200,000
    1.87 Acres
    Two-Story Office Building For Sale

    Multi-tenant office building in Bluffton, SC with income.

    10 Plantation Park Dr, Bluffton, SC 29910

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    Highway 278 Frontage Office Building
    Contact for pricing
    8,800 SF
    Highway 278 Frontage Office Building

    Class A office/medical building on Highway 278 in Bluffton.

    5 Buck Island Rd, Bluffton, SC 29910

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    Stand Alone Medical Office Building
    $1,348,000
    3,600 SF
    Stand Alone Medical Office Building

    Stand-alone medical building on Hilton Head Island, ready for occupancy.

    4101 Main St, Suite E & F, Hilton Head Island, SC 29926

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    Stand Alone Medical Building
    $1,348,000
    Stand Alone Medical Building

    Stand-alone medical building on Hilton Head Island for sale.

    4101 Main St, Suite E & F, Hilton Head Island, SC 29926

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    Office/Medical Suite Near Port Royal
    Contact for pricing
    1,484 SF
    Office/Medical Suite Near Port Royal

    1,484 SF office/medical suite for sale near Port Royal.

    1264 Ribaut Rd, Suite 302, Beaufort, SC 29902

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    Two-Story Office Building on Hilton Head
    $1,950,000
    9,600 SF
    Two-Story Office Building on Hilton Head

    9,600 SF office building in prime Hilton Head location.

    5 Dunmore Court, Hilton Head Island, SC 29926

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    Medical Office Suite Near Hospital
    Contact for pricing
    750 SF
    Medical Office Suite Near Hospital

    Ground floor medical office suite near Hilton Head Hospital.

    23 Main Street, Suite 101-A, Hilton Head Island, SC 29926

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    Medical Office Suite Near Hospital
    Contact for pricing
    1,500 SF
    Medical Office Suite Near Hospital

    Ground floor medical office suite available near Hilton Head Hospital.

    23 Main Street, Suite 101-A, Hilton Head Island, SC 29926

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    Bluffton Office/Medical Building For Sale
    Contact for pricing
    17,525 SF
    Bluffton Office/Medical Building For Sale

    Class A office/medical building fronting Highway 278 in Bluffton.

    5 Buck Island Rd, Bluffton, SC 29910

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    Medical Office Suites For Sale
    $2,861,037
    6,808 SF
    Medical Office Suites For Sale

    Four medical office suites totaling 6808 sqft for sale.

    14 Oak Forest Rd, Bluffton, SC 29910

    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Prime Commercial Lot For Rent
    $7,500/Mo

    Prime Commercial Lot For Rent

    0.66 acre commercial lot with high visibility.

    Tift Avenue N, Tifton, GA 31794
    View details
    Valdosta Commercial Land For Lease
    Contact for pricing
    43,560 SF

    Valdosta Commercial Land For Lease

    Prime commercial land in high-growth Valdosta corridor, suitable for various uses.

    Inner Perimeter Rd & Park Ave., Valdosta, GA 31602
    View details
    Prime Development Opportunity in Greenville
    Contact for pricing

    Prime Development Opportunity in Greenville

    1.27 acre interstate-visible land for ground lease or build-to-suit.

    39 Airpark Ct, Greenville, SC 29607
    View details
    WINTER PARK Land Lease Opportunity
    $8,500/Mo
    23,056 SF

    WINTER PARK Land Lease Opportunity

    Commercial land lease opportunity in Winter Park, Florida.

    5589 LAKE HOWELL ROAD, Winter Park, FL 32792
    View details

    Beaufort County, SC Medical Office Space Leasing Opportunities Market Analysis

    Explore Medical Office Space leasing options in Beaufort County, SC with 9 listings featured on our commercial real estate exchange. The current inventory includes 7,620 square feet of properties with an estimated lease value of $81 SF/Yr.

    Estimated lease rates for Medical Office Space in Beaufort County, SC begin at $20 SF/Yr, with an average of $27 SF/Yr and extend to $32 SF/Yr.
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    Browse Medical Office Space for Lease Near Beaufort, SC

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