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    Beaufort County, SC Medical Office Space for Lease

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    11 properties
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    Medical Office Suite with Shower
    Updated: Aug 17
    Medical Office Suite with Shower

    1264 Ribaut Road, Beaufort, SC 29902

    $2,845/Mo
    0.01 AC lot
    Approximately 1,484 square feet of medical or professional office space
    Two private offices, including one with a shower
    Open work area, dedicated data room, and one bathroom
    Existing plumbing, large water heater, and washer/dryer hookups
    Professional and medical complex with four named healthcare and dental practices
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    Turnkey Medical Office Space
    Updated: Sep 18
    Turnkey Medical Office Space

    53 Persimmon Street, Bluffton, SC 29910

    $33 SF/Yr
    0.10 AC lot
    3,445 SF medical and professional office space
    Existing medical‑office buildout with tile flooring
    Central air conditioning and electric heat
    Parking lot with accessible approach and ramp
    Public water and public sewer service
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    Medical Office Suite with Flexible Layout
    Medical Office Suite with Flexible Layout

    302-1264 Ribaut Road, Beaufort, SC 29902

    $2,845/Mo
    1,484 sqft

    Professional suite with private offices, a data room, plumbing capacity, and access to an established healthcare-oriented complex.

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    Office Suites with Highway Frontage
    Office Suites with Highway Frontage

    2 Westbury Park Way, Bluffton, SC 29910

    $32 SF/Yr
    3,870 sqft

    Two office suites are available with extensive Hwy 278 frontage and ample on-site parking for employees and visitors.

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    Medical Suites in Hilton Head
    Medical Suites in Hilton Head

    25 Hospital Center Blvd, Hilton Head Island, SC 29926

    Contact for pricing
    2,424 sqft

    Medical office suites for lease in prestigious medical complex.

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    Medical Building on Hilton Head
    Medical Building on Hilton Head

    4101 Main St, Suite E & F, Hilton Head Island, SC 29926

    $17 SF/Yr

    Stand-alone medical building for lease on Hilton Head Island.

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    Office/Medical Suite
    Office/Medical Suite

    1264 Ribaut Rd, Beaufort, SC 29902

    Contact for pricing
    1,484 sqft

    Suite offers a large open work area, two offices, data room, and one bathroom, plus washer/dryer hookups.

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    Single-Story Retail Office Medical Building
    Single-Story Retail Office Medical Building

    128 Bluffton Rd, Bluffton, SC 29910

    Contact for pricing
    2,730 sqft

    Pre-leasing is underway for a single-story retail, office, and medical building with a planned Fall 2026 delivery.

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    Single-Story Medical Office Retail
    Single-Story Medical Office Retail

    128 Bluffton Rd, Bluffton, SC 29910

    Contact for pricing
    2,655 sqft

    Pre-leasing single-story retail and office building planned for delivery in Fall 2026.

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    Class A Office Medical Building
    Class A Office Medical Building

    5 Buck Island Rd, Bluffton, SC 29910

    Contact for pricing
    17,525 sqft

    Class A office and medical building with floor-to-ceiling windows and an interior elevator at a highway intersection.

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    Ground-Floor Medical Office Suite
    Ground-Floor Medical Office Suite

    23 Main St, Hilton Head Island, SC 29926

    Contact for pricing
    750 sqft

    Ground-floor medical office suite in a high-profile building with ample on-site parking.

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    Based on your search, we've compiled 26 Potential Opportunities for your consideration. Besides 11 Active listings in Beaufort County, SC, we suggest exploring alternatives. Similar 15 Properties for Sales.

    Similar Spaces for Sale in Beaufort County, SC

    Consider Similar Space for Sale. We found 15 Spaces matching your search parameters.

    Two-Story Office Building with Elevator
    Two-Story Office Building with Elevator

    1044 William Hilton Pkwy, Hilton Head Island, SC 29928

    $2,200,000
    10,017 sqft

    Flexible layout with private offices, training areas, storage, and kitchenette or breakroom spaces.

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    Stand Alone Medical Office Building
    Stand Alone Medical Office Building

    4101 Main St, Suite E & F, Hilton Head Island, SC 29926

    $1,348,000
    3,600 sqft

    Stand-alone medical building on Hilton Head Island, ready for occupancy.

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    Built-Out Medical Office Space
    Built-Out Medical Office Space

    53 Persimmons Street STE 105, Bluffton, SC 29910

    Contact for pricing
    3,445 sqft

    Existing medical-office improvements support healthcare and professional occupancy, subject to the current lease and landlord approval.

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    Remodeled Two-Level Wellness Property
    Remodeled Two-Level Wellness Property

    16 Shelter Cove Lane, Hilton Head Island, SC 29928

    $1,999,000

    Updated standalone commercial space offers two floors and access to office, retail, medical, and professional business uses.

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    Leased Medical Office Space
    Leased Medical Office Space

    53 Persimmons Street, Bluffton, SC 29910

    $1,395,000

    A long-term medical tenant occupies the property under a lease with annual rent increases.

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    Highway 278 Frontage Office Building
    Highway 278 Frontage Office Building

    5 Buck Island Rd, Bluffton, SC 29910

    Contact for pricing
    8,800 sqft

    Class A office/medical building on Highway 278 in Bluffton.

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    Medical Office with CT Scanner
    Medical Office with CT Scanner

    14 Oak Forest Road, Bluffton, SC 29910

    $1,600,000

    Renovated in 2024, the suite combines imaging equipment with exam, laboratory, and patient-support areas.

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    Medical Office Suite Near Hospital
    Medical Office Suite Near Hospital

    23 Main Street, Suite 101-A, Hilton Head Island, SC 29926

    Contact for pricing
    750 sqft

    Ground floor medical office suite near Hilton Head Hospital.

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    Medical Office Suite Near Hospital
    Medical Office Suite Near Hospital

    23 Main Street, Suite 101-A, Hilton Head Island, SC 29926

    Contact for pricing
    1,500 sqft

    Ground floor medical office suite available near Hilton Head Hospital.

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    Medical Office Suite with Exam Rooms
    Medical Office Suite with Exam Rooms

    23 Main St, Hilton Head Island, SC 29926

    Contact for pricing
    1,213 sqft

    Medical office suite near Hilton Head Hospital with reception, waiting area, restroom, and multiple exam rooms.

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    Bluffton Office/Medical Building For Sale
    Bluffton Office/Medical Building For Sale

    5 Buck Island Rd, Bluffton, SC 29910

    Contact for pricing
    17,525 sqft

    Class A office/medical building fronting Highway 278 in Bluffton.

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    Built-Out Medical Office Space
    Built-Out Medical Office Space

    53 Persimmons Street, Bluffton, SC 29910

    Contact for pricing

    Existing professional improvements support medical, healthcare, and other office uses with limited additional build-out needs.

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    Hilton Head Office/Medical Space
    Hilton Head Office/Medical Space

    23 Main Street, Suite 303, Hilton Head Island, SC 29926

    $375,000

    Office/Medical space for sale near Hilton Head Hospital.

    View details

    Beaufort County, SC Medical Office Space Market Trends and Statistics

    Explore Medical Office Space leasing options in Beaufort County, SC with 11 listings featured on our commercial real estate exchange. The current inventory includes 32,922 square feet of properties with an estimated lease value of $105.01.

    Estimated lease rates for Medical Office Space in Beaufort County, SC begin at $17 SF/Yr, with an average of $26.25 SF/Yr and extend to $33 SF/Yr.
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    Featured Beaufort County Real Estate Agencies

    Realmo connects you with licensed Beaufort County CRE brokers providing property specifications, local market pricing, and commercial transaction underwriting support.

    Daniel Ravenel Sotheby's International Realty
    6 Promenade Street, Suite 1001 Bluffton, SC 29910
    Phone: 18437237150
    www.danielravenelsir.com/
    The HomesFinder Realty Group
    208 Carteret St. Beaufort, SC
    Phone: 18772294107
    Hilton Head Properties
    12 New Orleans Road Hilton Head Island, SC 29928
    Phone: 18437857111
    www.HiltonHeadProperties.biz
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