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    Beaufort County, SC Medical Office Space for Lease

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    Columbia, SC Greenville, SC Charleston, SC
    10 results
    Lady's Island Versatile Office Space
    $3,600 /Mo

    Lady's Island Versatile Office Space

    27 Kemmerlin Lane, Beaufort, SC 29907

    Well-conditioned office space ideal for medical, wellness, or traditional office.

    • Versatile 1,500 SF office space suitable for medical, wellness, salon, or traditional office use.
    • 7 treatment rooms with plumbing stubbed and capped.
    • Located in Kemmerlin Business Park with noteworthy businesses and organizations.
    • Newly renovated lobby, two ADA restrooms, and kitchenette.
    • Front and rear covered patios and ~15 shared parking spaces.
    Updated: Feb 24
    View details
    Versatile Commercial Space For Rent
    $4,500 /Mo

    Versatile Commercial Space For Rent

    8 Celadon Drive unit: A&B, Beaufort, SC 29907

    Two-story commercial building with flexible space and high visibility.

    • High‑visibility location at the corner of Sam's Point Road, ideal for brand establishment.
    • Modified Gross Lease at $4,000/month includes HOA, property taxes, building insurance, water, and trash collection.
    • Versatile two‑story building with 2250 sq ft of professional space, suitable for various business types.
    • Option to rent by unit: Unit A (ground floor) for $2,300 and Unit B (upper floor) for $2,200.
    • Ground floor features an open floor plan, polished concrete floors, high‑end finishes, dedicated entrance, and modern restroom.
    Updated: Nov 1, 2025
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    Highway 170 Retail/Office/Medical Space
    $36 SF/Yr

    Highway 170 Retail/Office/Medical Space

    Retail, office, or medical space for lease on Highway 170.

    48 Terrace Drive, Okatie, SC 29909
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    Bluffton Office/Medical Suites Available
    $28 SF/Yr
    3,870 SF

    Bluffton Office/Medical Suites Available

    Class A office and medical suites for rent in Bluffton.

    2 WESTBURY PKWY, Bluffton, SC
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    Medical Building on Hilton Head
    $22 SF/Yr

    Medical Building on Hilton Head

    Stand-alone medical building for lease on Hilton Head Island.

    4101 Main St, Suite E & F, Hilton Head Island, SC 29926
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    North End Hilton Head Offices
    $22 SF/Yr

    North End Hilton Head Offices

    Professional office/medical spaces for lease on Hilton Head Island.

    100 Exchange Street, Hilton Head Island, SC 29926
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    Bluffton Retail/Office/Medical Building
    $35 SF/Yr

    Bluffton Retail/Office/Medical Building

    Pre-leasing single-story retail/office/medical building in the heart of Bluffton.

    128 Bluffton Road, 29910, SC, Bluffton, SC 29910
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    Medical Suites in Hilton Head
    Contact for pricing

    Medical Suites in Hilton Head

    Medical office suites for lease in prestigious medical complex.

    Hilton Head Island, SC 29926
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    Okatie Outpatient Surgery Center Shell
    Contact for pricing
    1,556 SF

    Okatie Outpatient Surgery Center Shell

    Shell space available in Okatie Outpatient Surgery Center.

    40-48 Okatie Center Blvd S, Okatie, SC
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    Medical Suites in Hilton Head
    Contact for pricing

    Medical Suites in Hilton Head

    Medical suites for lease in Hilton Head's medical district.

    25 Hospital Center Blvd, Hilton Head Island, SC 29926
    View details
    Based on your search, we've compiled 29 Potential Opportunities for your consideration. Besides 10 Active listings in Beaufort County, SC, we suggest exploring alternatives. Similar 15 Properties for Sales.

    Explore Similar Spaces for Sale in Beaufort County, SC

    Consider Similar Space for Sale. We found 15 Spaces matching your search parameters.

    Leased Medical Space For Sale
    $647,111

    Leased Medical Space For Sale

    100% leased medical space with new long-term lease.

    14 Oak Forest Road, Bluffton, SC 29910
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    Leased Medical Space For Sale
    $628,148

    Leased Medical Space For Sale

    100% leased medical space with new 5-year lease.

    14 Oak Forest Road, Bluffton, SC 29910
    View details
    Leased Medical Space For Sale
    $1,609,481

    Leased Medical Space For Sale

    100% leased medical space with new long-term lease.

    14 Oak Forest Road, Bluffton, SC 29910
    View details
    Hilton Head Office/Medical Space
    $375,000

    Hilton Head Office/Medical Space

    Office/Medical space for sale near Hilton Head Hospital.

    23 Main Street, Suite 303, Hilton Head Island, SC 29926
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    Highway 278 Frontage Office Building
    Contact for pricing
    8,800 SF

    Highway 278 Frontage Office Building

    Class A office/medical building on Highway 278 in Bluffton.

    5 Buck Island Rd, Bluffton, SC 29910
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    Stand Alone Medical Office Building
    $1,348,000
    3,600 SF

    Stand Alone Medical Office Building

    Stand-alone medical building on Hilton Head Island, ready for occupancy.

    4101 Main St, Suite E & F, Hilton Head Island, SC 29926
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    Two-Story Office Building For Sale
    $2,200,000

    Two-Story Office Building For Sale

    Multi-tenant office building in Bluffton, SC with income.

    10 Plantation Park Dr, Bluffton, SC 29910
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    Stand Alone Medical Building
    $1,348,000

    Stand Alone Medical Building

    Stand-alone medical building on Hilton Head Island for sale.

    4101 Main St, Suite E & F, Hilton Head Island, SC 29926
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    Two-Story Office Building on Hilton Head
    $1,950,000
    9,600 SF

    Two-Story Office Building on Hilton Head

    9,600 SF office building in prime Hilton Head location.

    5 Dunmore Court, Hilton Head Island, SC 29926
    View details
    Office/Medical Suite Near Port Royal
    Contact for pricing
    1,484 SF

    Office/Medical Suite Near Port Royal

    1,484 SF office/medical suite for sale near Port Royal.

    1264 Ribaut Rd, Suite 302, Beaufort, SC 29902
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    Office/Medical Suite Near Port Royal
    Contact for pricing
    3,224 SF

    Office/Medical Suite Near Port Royal

    Office/medical suite for lease near Port Royal in Beaufort, SC.

    1264 Ribaut Rd, Suite 302, Beaufort, SC 29902
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    Bluffton Office/Medical Building For Sale
    Contact for pricing
    17,525 SF

    Bluffton Office/Medical Building For Sale

    Class A office/medical building fronting Highway 278 in Bluffton.

    5 Buck Island Rd, Bluffton, SC 29910
    View details
    Medical Office Suite Near Hospital
    Contact for pricing
    750 SF

    Medical Office Suite Near Hospital

    Ground floor medical office suite near Hilton Head Hospital.

    23 Main Street, Suite 101-A, Hilton Head Island, SC 29926
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    Medical Office Suite Near Hospital
    Contact for pricing
    1,500 SF

    Medical Office Suite Near Hospital

    Ground floor medical office suite available near Hilton Head Hospital.

    23 Main Street, Suite 101-A, Hilton Head Island, SC 29926
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Prime Commercial Lot For Rent
    $7,500 /Mo

    Prime Commercial Lot For Rent

    0.66 acre commercial lot with high visibility.

    Tift Avenue N, Tifton, GA 31794
    View details
    Valdosta Commercial Land For Lease
    Contact for pricing
    43,560 SF

    Valdosta Commercial Land For Lease

    Prime commercial land in high-growth Valdosta corridor, suitable for various uses.

    0 Inner Perimeter Rd & Park Ave., Valdosta, GA 31602
    View details
    Winter Park Mixed-Use Opportunity
    $8,500 /Mo
    23,056 SF

    Winter Park Mixed-Use Opportunity

    Double commercial lot in Winter Park, FL, for lease.

    5589 LAKE HOWELL ROAD, Winter Park, FL 32792
    View details
    Highway 72 Corner Lot
    $6,500 /Mo
    1,875 SF

    Highway 72 Corner Lot

    1.6 acre commercial lot for rent on Highway 72.

    30472 Highway 72, Madison, AL 35756
    View details

    Beaufort County, SC Medical Office Space Leasing Opportunities Market Analysis

    Explore Medical Office Space leasing options in Beaufort County, SC with 10 listings featured on our commercial real estate exchange. The current inventory includes 1,079,364,530 square feet of properties with an estimated lease value of $71 SF/Yr.

    Estimated lease rates for Medical Office Space in Beaufort County, SC begin at $2 SF/Yr, with an average of $23 SF/Yr and extend to $41 SF/Yr.
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    Medical Office Space by market

    Browse Medical Office Space for Lease Near Beaufort, SC

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