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    Dorchester County, SC Medical Office Space for Lease

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    Greenville, SC Columbia, SC Charleston, SC
    9 results
    North Charleston Office Space Available
    $19 SF/Yr
    1,664 SF

    North Charleston Office Space Available

    2070 Northbrook Blvd, North Charleston, SC

    Office space for rent in North Rivers Business Center.

    • High Occupancy Rate (98%) indicating strong tenant demand and income stability
    • Diverse Tenant Mix including medical, government, and professional office users
    • Presence of well‑known tenants such as MUSC Children's Health Clinic and Roper St. Francis ATI
    • Strategic Location with accessibility from Rivers Avenue and Northbrook Blvd
    • Includes two buildings totaling 79,611 SF
    Updated: Oct 29, 2025
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    Summerville Professional Office Space
    Contact for pricing
    2,300 SF

    Summerville Professional Office Space

    607 West 5th North Street, Summerville, SC 29483

    Professional office space for lease in Summerville, SC.

    • Excellent location with strong street frontage, visibility, and parking on Highway 78.
    • ±2,300 SF professional office space suitable for various uses (medical, accounting, etc.).
    • Includes six (6) private offices, large conference room, reception area, kitchen/break room, and two (2) ADA‑compliant restrooms.
    • Ready for occupancy April 1.
    • Proximity to Downtown Summerville, Main Street, and the Nexton growth corridor.
    Updated: Mar 7
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    Former Daycare Near Navy Yard
    Contact for pricing
    12,895 SF

    Former Daycare Near Navy Yard

    12,895 SF former daycare near new Navy Yard.

    1910 McMillan Avenue, North Charleston, SC 29405
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    Class A Medical Office Space
    $30 SF/Yr
    1,647 SF

    Class A Medical Office Space

    Premier medical office space near Roper St. Francis Hospital.

    4600 Goer Dr, North Charleston, SC
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    Class A Medical Office Space
    Contact for pricing
    12,000 SF

    Class A Medical Office Space

    Class A medical/general office space in Nexton mixed-use development.

    655 Scholar Way, Summerville, SC 29486
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    Turnkey Dental Office Sublease Opportunity
    Contact for pricing

    Turnkey Dental Office Sublease Opportunity

    Sublease opportunity for a turnkey dental office in Ladson.

    9403 Hwy 78 # 201, Ladson, SC 29456
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    Medical/Professional Office Suite For Rent
    $4,078/Mo
    1,830 SF

    Medical/Professional Office Suite For Rent

    1,830 SF medical/professional office suite near Trident Hospital Campus.

    2831 Tricom St, North Charleston, SC
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    North Charleston Office Space Available
    $25 SF/Yr
    903 SF

    North Charleston Office Space Available

    Professional office space for lease in North Charleston, SC.

    8700 North Park Boulevard, North Charleston, SC
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    Professional Office Suite For Rent
    Contact for pricing
    853 SF

    Professional Office Suite For Rent

    Professional office suite suitable for small business or medical practice.

    310 N Gum Street # A, Summerville, SC 29483
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    Based on your search, we've compiled 22 Potential Opportunities for your consideration. Besides 9 Active listings in Dorchester County, SC, we suggest exploring alternatives. Similar 9 Properties for Sales.

    Similar Spaces for Sale in Dorchester County, SC

    Consider Similar Space for Sale. We found 9 Spaces matching your search parameters.

    Former Daycare Near Navy Yard
    $2,300,000
    12,895 SF
    Former Daycare Near Navy Yard

    12,895 SF former daycare near new Navy Yard project.

    1910 McMillan Avenue, North Charleston, SC 29405

    View details
    Dorchester Road Office Space Available
    $1,150,000
    6,600 SF
    Dorchester Road Office Space Available

    High-traffic location with flexible spaces for professional uses.

    7880-7890 Dorchester Rd, North Charleston, SC

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    North Charleston Medical Office Building
    $1,500,000
    4,345 SF
    North Charleston Medical Office Building

    Commercial property suitable for medical or professional office use.

    3800 Faber Place Drive, North Charleston, SC 29405

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    Nexton Mixed-Use Development Opportunity
    $18,000,000
    30,000 SF
    Nexton Mixed-Use Development Opportunity

    Mixed-use property for sale or lease in Nexton, Summerville.

    1227 Nexton Pkwy, Summerville, SC 29486

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    Renovated Office Building Near I-26
    Contact for pricing
    71,711 SF
    Renovated Office Building Near I-26

    71,354 SF office building with recent $2M renovation.

    4975 Lacross Road, North Charleston, SC 29406

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    Medical Office Space Available
    $2,050,000
    2,423 SF
    Medical Office Space Available

    Professional office suites for lease in thriving medical complex.

    85 Springview Ln, Summerville, SC

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    White Hall Center Office Condo
    $549,900
    2,000 SF
    White Hall Center Office Condo

    Office condo in White Hall Center, North Charleston.

    5401 Netherby Lane Ste 102, North Charleston, SC 29420

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    Pad-Ready Building Sites Available
    Contact for pricing
    8,400 SF
    Pad-Ready Building Sites Available

    Three separate building sites for sale or build-to-suit.

    3700 Ingleside Boulevard, Ladson, SC 29456

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    Nexton Mixed-Use Development Opportunity
    Contact for pricing
    30,000 SF
    Nexton Mixed-Use Development Opportunity

    Mixed-use property in Nexton with office, retail, and restaurant spaces.

    1227 Nexton Pkwy, Summerville, SC

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    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Prime Development Opportunity in Greenville
    Contact for pricing

    Prime Development Opportunity in Greenville

    1.27 acre interstate-visible land for ground lease or build-to-suit.

    39 Airpark Ct, Greenville, SC 29607
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    Prime Commercial Lot For Rent
    $7,500/Mo

    Prime Commercial Lot For Rent

    0.66 acre commercial lot with high visibility.

    Tift Avenue N, Tifton, GA 31794
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    Valdosta Commercial Land For Lease
    Contact for pricing
    43,560 SF

    Valdosta Commercial Land For Lease

    Prime commercial land in high-growth Valdosta corridor, suitable for various uses.

    Inner Perimeter Rd & Park Ave., Valdosta, GA 31602
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    WINTER PARK Land Lease Opportunity
    $8,500/Mo
    23,056 SF

    WINTER PARK Land Lease Opportunity

    Commercial land lease opportunity in Winter Park, Florida.

    5589 LAKE HOWELL ROAD, Winter Park, FL 32792
    View details

    Dorchester County, SC Medical Office Space Leasing Opportunities Market Analysis

    Explore Medical Office Space leasing options in Dorchester County, SC with 9 listings featured on our commercial real estate exchange. The current inventory includes 6,044 square feet of properties with an estimated lease value of $101 SF/Yr.

    Estimated lease rates for Medical Office Space in Dorchester County, SC begin at $19 SF/Yr, with an average of $25 SF/Yr and extend to $30 SF/Yr.
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