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Greenville, SC Office Spaces for Lease

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202 properties
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Two-Suite Office Property
Updated: Aug 6
Two-Suite Office Property

221 Adley Way, Greenville, SC 29607

$1,000/Mo
0.06 AC lot
Two private office suites located on the upstairs level
Professional office setting in the Woodruff Road business corridor
Access to Woodruff Road, I‑385, and I‑85
Ample parking at the office building
Brick construction with carpeted interiors
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Updated Office Suite with Private Offices
Updated: Jul 20
Updated Office Suite with Private Offices

413 Vardry Street, Greenville, SC 29601

$2,499/Mo
0.15 AC lot
5 private offices, including one with a private bathroom
5 dedicated parking spaces in front of the unit, plus overflow parking
Vaulted ceilings with exposed ductwork throughout the office
Reception area, conference room, small breakroom, and ADA bathroom
Located in Greenville’s Historic West End near Fluor Field and South Main Street
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Renovated Office Unit
Renovated Office Unit

413 Vardry Street, Greenville, SC 29601

$2,649/Mo
0.10 AC lot

Office space with private offices, conference rooms, reception, ADA access, parking, and building signage options.

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Single-Story Freestanding Office Building
Single-Story Freestanding Office Building

1313A Miller Road, Greenville, SC 29607

$16.50 SF/Yr
4,000 sqft

Functional single-story office layout with multiple private offices, open bullpen space, conference room, and on-site parking.

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Renovated Downtown Office Units
Renovated Downtown Office Units

200 N Main Street, Greenville, SC 29601

$550/Mo
0.10 AC lot

Flexible professional suites with shared conference, kitchenette, and visitor waiting amenities.

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Brick Office Units with Lobby
Brick Office Units with Lobby

413 Vardry Street, Greenville, SC 29601

$900/Mo
0.04 AC lot

Single-level suites offer windowed offices, natural light, and available building signage.

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Automotive Property with Display Yard
Automotive Property with Display Yard

4707 White Horse Road, Greenville, SC 29611

$3,800/Mo
1.00 AC lot

C-2-zoned site includes an office building and rear metal structure for dealership operations.

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Office Building with Dedicated Parking
Office Building with Dedicated Parking

810 Pendleton Street, Greenville, SC 29601

$22 SF/Yr
3,850 sqft

Flexible downtown office layout with multiple conference spaces, restrooms, and 12 dedicated parking spaces on-site.

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Warehouse Space Near I-85
Warehouse Space Near I-85

1138 White Horse Rd, Greenville, SC 29605

$9.50 SF/Yr
4,950 sqft

Warehouse space for lease near I-85 in Greenville, SC.

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Office Suite 910
Office Suite 910

75 Beattie Place, Greenville, SC 29601

$34.50 SF/Yr
3,389 sqft

For rent office suite 910 offering 3,389 sq. ft. within a commercial office building.

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Move-In Ready Office Building
Move-In Ready Office Building

30 Pointe Cir, Greenville, SC 29615

$5,900/Mo
5,900 sqft

Move-in ready office building with reception, 16+ private offices, conference space, and four garage bays.

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Downtown Greenville Office Space
Downtown Greenville Office Space

22 S Main St, Greenville, SC 29601

$22.50 SF/Yr
10,308 sqft

Turnkey office space with high-end finishes and Main Street views.

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Office Space For Lease
Office Space For Lease

7006 Pelham Rd, Greenville, SC 29615

$12 SF/Yr
2,500 sqft

First floor office space available for lease.

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Class A Mixed-Use Redevelopment
Class A Mixed-Use Redevelopment

400 Augusta Street, Greenville, SC 29601

$28 SF/Yr
3,190 sqft

Located in Greenville’s Historic Westend, easily accessible to major routes.

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Class A Office Building with Retail
Class A Office Building with Retail

3 Research Drive, Greenville, SC 29607

$1,208/Mo
1,208 sqft

Class A office building on the CU-ICAR campus with a LEED Silver certification, plus a ground-floor retail/office suite.

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West Greenville Studio Space Available
West Greenville Studio Space Available

31 Burdette St, Greenville, SC 29611

$850/Mo
4,667 sqft

Creative studios and workspaces in dynamic West Greenville neighborhood.

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Downtown Greenville Office Space Available
Downtown Greenville Office Space Available

101 North Main Street, Greenville, SC 29601

$36.50 SF/Yr
18,457 sqft

Office space for rent in downtown Greenville with amenities.

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Greenville Office Building For Rent
Greenville Office Building For Rent

84 Villa Road, Greenville, SC 29615

$21.50 SF/Yr
25,640 sqft 1.00 AC lot

Up to 25,640 SF available near I-385.

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Prime Office Space Near Museums
Prime Office Space Near Museums

301 College St, Greenville, SC 29601

$28 SF/Yr
130,000 sqft

Up to 130,000 SF available near Greenville's cultural hub.

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Warehouse and Office Space Available
Warehouse and Office Space Available

46 Oeland Drive |, Greenville, SC 29609

$6.75 SF/Yr
10,000 sqft

10,000 SF warehouse/office space near downtown Greenville for lease.

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Greenville Office Space for Lease
Greenville Office Space for Lease

2000 Wade Hampton Boulevard, Greenville, SC 29615

$19 SF/Yr
188,900 sqft

Up to 188,900 SF available, near Downtown Greenville.

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Office Space Available For Rent
Office Space Available For Rent

121 Interstate Boulevard, Greenville, SC 29615

$7.50 SF/Yr
4,900 sqft

Office space available for lease in Greenville, SC.

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Modern Office Space with Amenities
Modern Office Space with Amenities

30 Patewood Drive, Greenville, SC 29615

$28.50 SF/Yr
7,915 sqft

Office space with tenant lounge, fitness center, and food trucks.

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Greenville Office Space For Rent
Greenville Office Space For Rent

1 Marcus Drive, Greenville, SC 29615

$15.75 SF/Yr
17,569 sqft

Office building with easy access to major roads and downtown.

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Greenville, SC Office Spaces Lease Rates & Market Statistics

Browse 202 Office Spaces for lease in Greenville, SC on Realmo, a commercial real estate marketplace serving the Greenville area. The current inventory totals 2,761,344 square feet of properties — an average of ~13,650 SF per listing.

Office Spaces lease rates in Greenville range from $6.75 SF/Yr at the entry level to $47.50 SF/Yr at the top of the market, averaging $24.54 SF/Yr. That's a 7x spread between entry-level and premium space, making side-by-side comparison of asking rents and lease terms essential. At $24.54 SF/Yr, the local average runs 5% above South Carolina's state average of $23.45 SF/Yr.

Greenville accounts for 86% of the 234 office spaces currently available across Greenville County, where nearby markets include Greer and Simpsonville. By space type, the market includes 131 office units, 53 office buildings and 10 medical office space listings — medical office space options typically offer the lowest entry point, while office units command the highest rates.

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