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    South Carolina Retail Properties & Spaces for Lease

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    Columbia, SC Greenville, SC Charleston, SC
    1,248 results
    Highway 170 Flex/Retail Building
    $7,500 /Mo

    Highway 170 Flex/Retail Building

    46 Robert Smalls Parkway, Beaufort, SC 29906

    4,350 SF flex/retail building with high visibility.

    • Excellent visibility and direct frontage on the Spanish Moss Trail.
    • Signalized corner location across from Publix and Beaufort Plaza.
    • Located on rapidly growing Hwy 170 corridor.
    • Versatile layout can be subdivided into multiple units.
    • Significant improvements underway, including interior and exterior paint, new flooring, and cleanup/demo.
    Updated: Mar 17
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    Versatile Flex Space in Myrtle Beach
    $4,750 /Mo
    4,110 SF

    Versatile Flex Space in Myrtle Beach

    716 8th Ave. N, Myrtle Beach, SC 29577

    Adaptable commercial space for lease in the Arts & Innovation District.

    • Highly visible flex‑use commercial space in the heart of Myrtle Beach's Arts & Innovation District.
    • Approximately 4,500 sq ft across two floors, suitable for office, storefront, and warehouse/operational needs.
    • Features a reception area, multiple offices, conference room, two kitchens, and two restrooms.
    • Rear garage door provides flexibility for deliveries, storage, or service‑based operations.
    • Flexible zoning and no on‑site parking requirements offer versatility for various commercial uses.
    Updated: Jan 31
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    Commercial Space in Beaufort Plaza
    $1,400 /Mo

    Commercial Space in Beaufort Plaza

    Retail space available for lease in Beaufort, South Carolina.

    1180 Ribaut Road unit: 7, Beaufort, SC 29902
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    Retail Space in Beaufort, SC
    $690 /Mo

    Retail Space in Beaufort, SC

    Large open retail space with storage and abundant parking.

    3 County Shed Road, Beaufort, SC 29906
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    Retail Center Renovation in Little River
    $1,913 /Mo
    1,148 SF

    Retail Center Renovation in Little River

    Retail and office spaces available in renovated Little River center.

    4390 Spa Dr., Little River, SC 29566
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    New Flex Development in Murrells
    $3,000 /Mo
    1,625 SF

    New Flex Development in Murrells

    New construction flex space with build-to-suit options available.

    4960 Highway 17, Murrells Inlet, SC 29576
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    Downtown Wagener Commercial Space Available
    $1,695 /Mo
    1,375 SF

    Downtown Wagener Commercial Space Available

    Premier commercial space in downtown Wagener, move-in ready and versatile.

    108 Park Street NW, Wagener, SC 29164
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    Historic Pendleton Bank Retail Space
    $3,500 /Mo

    Historic Pendleton Bank Retail Space

    Renovated retail space in historic Pendleton Town Square.

    104 Exchange Street, Pendleton, SC 29670
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    Retail Space in Columbus Plaza
    $1,000 /Mo
    1,000 SF

    Retail Space in Columbus Plaza

    1,000 SF retail space for lease in Myrtle Beach.

    3721 Wesley St., Myrtle Beach, SC 29579
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    Retail Space in Little River
    $3,333 /Mo
    2,000 SF

    Retail Space in Little River

    Retail space available in high-traffic Little River shopping center.

    4390 Spa Dr., Little River, SC 29566
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    Retail/Flex Building on Highway 170
    $11 SF/Yr

    Retail/Flex Building on Highway 170

    19,250 SF retail/flex building with excellent exposure.

    164 Robert Smalls Parkway, Beaufort, SC 29906
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    Retail Space in Little River
    $1,931 /Mo
    1,159 SF

    Retail Space in Little River

    Retail space available in high-traffic Little River location.

    4390 Spa Dr., Little River, SC 29566
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    Downtown Beaufort Commercial Space Available
    $3,300 /Mo

    Downtown Beaufort Commercial Space Available

    Versatile commercial space in the heart of Downtown Beaufort.

    700 Bay unit: 105A, Beaufort, SC 29902
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    Murrells Inlet Office Space
    $2,187 /Mo
    1,250 SF

    Murrells Inlet Office Space

    Multi-tenant office/retail/medical building with 1,250 SF available 4/1/26.

    637 Bellamy Ave., Murrells Inlet, SC 29576
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    Aiken Industrial Space For Rent
    $8,000 /Mo
    15,080 SF

    Aiken Industrial Space For Rent

    15,080 SF industrial space on Equestrian Corridor.

    2969 Wagener Road unit: A1, Aiken, SC 29801
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    Versatile Commercial Space For Rent
    $4,500 /Mo

    Versatile Commercial Space For Rent

    Two-story commercial building with flexible space and high visibility.

    8 Celadon Drive unit: A&B, Beaufort, SC 29907
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    Pawleys Island Class A Office
    $2,250 /Mo
    1,800 SF

    Pawleys Island Class A Office

    Class A office space in the heart of Pawleys Island.

    12019 Ocean Hwy., Pawleys Island, SC 29585
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    Retail Space on Highway 17
    $8,624 /Mo
    4,500 SF

    Retail Space on Highway 17

    Established retail space with highway frontage in Myrtle Beach.

    10589 N Kings Highway, Myrtle Beach, SC 29572
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    Versatile Commercial Space in Florence
    $5,000 /Mo
    11,390 SF

    Versatile Commercial Space in Florence

    Commercial property with bay doors, ideal for automotive or warehouse.

    374 Darlington St., Florence, SC 29501
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    High-Visibility Gas Station & Store
    $23 SF/Yr

    High-Visibility Gas Station & Store

    Gas station and convenience store with high visibility and traffic.

    5 Lane Street, Yemassee, SC 29945
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    Prime Commercial Site in Port Royal
    $6,000 /Mo

    Prime Commercial Site in Port Royal

    High-visibility commercial site ideal for retail, professional, and food businesses.

    1670 Ribaut Road, Port Royal, SC 29935
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    New Retail and Office Spaces
    $6,082 /Mo
    2,500 SF

    New Retail and Office Spaces

    New retail and office spaces available in Pawleys Island, SC.

    9601 Ocean Highway, Pawleys Island, SC 29585
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    Restaurant Space Near I-95
    $7,680 /Mo
    4,190 SF

    Restaurant Space Near I-95

    Restaurant space for lease with high visibility and traffic.

    3751 W Palmetto St, Florence, SC 29501
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    Prime Retail/Office Space Available
    $3,329 /Mo
    1,598 SF

    Prime Retail/Office Space Available

    Highly desirable Pawleys Island mixed-use location. Adaptable space.

    71 Da Gullah Way, Pawleys Island, SC 29585
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    South Carolina Retail properties & Spaces Leasing Opportunities Market Analysis

    Explore Retail properties & Spaces leasing options in South Carolina with 1248 listings featured on our commercial real estate exchange. The current inventory includes 79,361,005,648 square feet of properties with an estimated lease value of $4,542 /Mo.

    Estimated lease rates for Retail properties & Spaces in South Carolina begin at $0.53 SF/Yr, with an average of $23 SF/Yr and extend to $240 SF/Yr.
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