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    Charleston County, SC Office Spaces for Lease

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    Greenville, SC Columbia, SC Charleston, SC
    64 results
    Gregorie Ferry Landing
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    Professional Office Space For Rent
    $895/Mo
    Professional Office Space For Rent

    845 Lowcountry Blvd, Mount Pleasant, SC 29464

    Prime location office building with walkable access to local favorites.
    • Prime location on Lowcountry Blvd with exceptional visibility and accessibility.
    • Free on‑site parking.
    • Walkable access to local favorites like Second State Coffee and Langdon’s Restaurant & Wine Bar.
    • Convenient access to Hwy 17.
    • Less than 10 minutes from downtown Charleston or the beach.
    Updated: Mar 7
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    Office Space Near Shopping Center
    $1,300/Mo
    Office Space Near Shopping Center

    1004 Anna Knapp Blvd, Mount Pleasant, SC 29464

    Second-floor office space with natural light and free parking.
    • Across from Publix anchored Queensboro Shopping Center
    • Plethora of nearby amenities, including Chick‑fil‑A
    • Free, on‑site parking
    • Two large windows providing natural light
    • Available immediately
    Updated: Apr 29
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    Industrial Complex with Flexible Units
    $15 SF/Yr
    4,533 SF
    Industrial Complex with Flexible Units

    Multi-building industrial complex with modern construction and efficient layouts.

    4509 Savannah Highway, Ravenel, SC 29470

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    Class A Medical Office Building
    $28 SF/Yr
    14,084 SF
    Class A Medical Office Building

    Renovated medical/office building with ample parking in Mt. Pleasant.

    1200 Innovation Way, Mount Pleasant, SC 29466

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    Functional Space in Sea Island
    $12 SF/Yr
    2,710 SF
    Functional Space in Sea Island

    2,710 SF warehouse and office space for lease.

    3609 River Road, Johns Island, SC 29455

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    Mount Pleasant Office Space Available
    $895/Mo
    Mount Pleasant Office Space Available

    Office space for rent with parking, Wi-Fi, and conference room.

    845 Lowcountry Blvd, Mount Pleasant, SC 29464

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    Class A Office Condo
    $22 SF/Yr
    2,000 SF
    Class A Office Condo

    High-end office condo available for lease in Mt. Pleasant.

    505 Belle Hall Parkway, Mount Pleasant, SC 29464

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    Office Suite in Mt. Pleasant
    $30 SF/Yr
    1,245 SF
    Office Suite in Mt. Pleasant

    Office suite with private offices, reception, and conference room.

    782 Johnnie Dodds Boulevard #E, Mount Pleasant, SC 29464

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    Medical Office in Mt. Pleasant
    $34 SF/Yr
    60,809 SF
    Medical Office in Mt. Pleasant

    Medical office space available for sublease in Mt. Pleasant.

    1300 Hospital Dr, Mount Pleasant, SC 29464

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    Mount Pleasant Office Space Available
    $28 SF/Yr
    352 SF
    Mount Pleasant Office Space Available

    Office space in a well-maintained park with included utilities.

    503 Wando Park Blvd, Mount Pleasant, SC

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    Mount Pleasant Office Space Available
    $26 SF/Yr
    2,227 SF
    Mount Pleasant Office Space Available

    Office space available for lease in Mount Pleasant, SC.

    1671 Belle Isle Avenue, Mount Pleasant, SC 29464

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    New Office Building in Mount Pleasant
    $37 SF/Yr
    9,849 SF
    New Office Building in Mount Pleasant

    Newly constructed office building in desirable Mount Pleasant location.

    1681 Belle Isle Ave, Mount Pleasant, SC

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    Single-Story Office in Wando Commons
    $24 SF/Yr
    2,263 SF
    Single-Story Office in Wando Commons

    Single-story office space with convenient access to major routes.

    498 Wando Park Blvd, Mount Pleasant, SC

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    Mount Pleasant Office Park Space
    Contact for pricing
    1,245 SF
    Mount Pleasant Office Park Space

    Office park with visibility, access, and nearby amenities for rent.

    782 Johnnie Dodds Boulevard, Mount Pleasant, SC 29464

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    Mount Pleasant Office Space Available
    $28 SF/Yr
    2,400 SF
    Mount Pleasant Office Space Available

    Office space available for lease in Mount Pleasant, SC.

    880 Johnnie Dodds Boulevard, Mount Pleasant, SC 29464

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    Mount Pleasant Office Space Available
    $30 SF/Yr
    3,400 SF
    Mount Pleasant Office Space Available

    3,400 SF office space with ample parking and signage.

    790 Johnnie Dodds Blvd, Mount Pleasant, SC

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    Class A Flex Space
    Contact for pricing
    4,380 SF
    Class A Flex Space

    Flex building with showroom/office and fully conditioned warehouse space.

    547 Long Point Road # 104, Mount Pleasant, SC 29464

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    Class A Flex Space Available
    Contact for pricing
    4,380 SF
    Class A Flex Space Available

    Flex space with showroom/office and warehouse, convenient location.

    547 Long Point Road, Mount Pleasant, SC 29464

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    Showroom and Office Space
    $30 SF/Yr
    1,000 SF
    Showroom and Office Space

    1,000 SF showroom/office space on Maybank Highway for rent.

    3436 Maybank Hwy, Johns Island, SC

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    Renovated Office Suite in Mt. Pleasant
    Contact for pricing
    Renovated Office Suite in Mt. Pleasant

    Executive office suite available for sublease, renovated in 2024.

    1004 Anna Knapp Boulevard, Suite 3, Mount Pleasant, SC 29464

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    Mount Pleasant Office Space Available
    $18 SF/Yr
    1,600 SF
    Mount Pleasant Office Space Available

    Office space featuring private offices, conference area, and kitchen.

    1041 Johnnie Dodds Blvd, Mount Pleasant, SC

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    Freestanding Office Building For Lease
    $20 SF/Yr
    3,400 SF
    Freestanding Office Building For Lease

    Two-story office property in a rapidly developing commercial corridor.

    890 JOHNNIE DODDS BLVD, Mount Pleasant, SC

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    Turn Key Medical Office Space
    $27 SF/Yr
    2,587 SF
    Turn Key Medical Office Space

    Move-in ready medical office space near East Cooper Hospital.

    897 Von Kolnitz Rd, Mount Pleasant, SC

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    Charleston County, SC Office Spaces Leasing Opportunities Market Analysis

    Explore Office Spaces leasing options in Charleston County, SC with 64 listings featured on our commercial real estate exchange. The current inventory includes 272,124 square feet of properties with an estimated lease value of $1,232 /Mo.

    Estimated lease rates for Office Spaces in Charleston County, SC begin at $12 SF/Yr, with an average of $31 SF/Yr and extend to $140 SF/Yr.
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