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    York County, SC Medical Office Space for Lease

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    Greenville, SC Columbia, SC Charleston, SC
    12 results
    Spacious Office and Medical Suite
    $29 SF/Yr
    8,988 SF

    Spacious Office and Medical Suite

    345 Patricia Lane, Fort Mill, SC 29708

    8,988 SF professional office/medical suite in Fort Mill, SC.

    • Expansive 8,988 SF professional office/medical suite.
    • Premier location in Fort Mill with unbeatable proximity to I‑77, Gold Hill Road, and Tega Cay.
    • Highly functional layout with six massive open rooms (each over 700 square feet).
    • Ideal environment within an established park alongside a strong mix of medical tenants.
    • Ultimate flexibility for collaborative workspaces, training centers, or large‑scale clinical use.
    Updated: May 18
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    Rock Hill Medical/Office Suites
    $18 SF/Yr
    2,100 SF

    Rock Hill Medical/Office Suites

    420 S Herlong Ave, Rock Hill, SC 29732

    Medical/office suites in established Rock Hill medical complex for rent.

    • Unbeatable proximity to Piedmont Medical Center
    • Located in an established Rock Hill medical complex
    • Functional layout easily adaptable for healthcare or professional practices
    • Ground‑level suites
    • Highly accessible commercial corridor location
    Updated: May 18
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    Medical Office Space For Rent
    $30 SF/Yr
    2,330 SF

    Medical Office Space For Rent

    Medical office space in established park, convenient location.

    105 Ben Casey Dr, Fort Mill, SC 29708
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    Medical/Office Space in Rock Hill
    $18 SF/Yr
    2,598 SF

    Medical/Office Space in Rock Hill

    Established medical complex with adaptable suites near key locations.

    410 S Herlong Ave, Rock Hill, SC 29732
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    Downtown Fort Mill Office Space
    $8 SF/Yr

    Downtown Fort Mill Office Space

    Private rooms available within established wellness center in Fort Mill.

    227 Main St, Fort Mill, SC 29715
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    Rock Hill Medical Office Space
    $2,600/Mo

    Rock Hill Medical Office Space

    Move-in ready medical office space near Piedmont Medical Center.

    744 Arden Lane, Rock Hill, SC 29732
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    Medical Office on Oakland Avenue
    Contact for pricing
    3,600 SF

    Medical Office on Oakland Avenue

    3,600 SF medical office space for lease in Rock Hill.

    356 Oakland Avenue, Rock Hill, SC 29732
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    Medical/Professional Office Space Available
    Contact for pricing
    1,200 SF

    Medical/Professional Office Space Available

    Office space with frontage near Piedmont Medical Center.

    235 S. Herlong Avenue, Rock Hill, SC 29732
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    Retail Space in Riverwalk Community
    Contact for pricing
    2,662 SF

    Retail Space in Riverwalk Community

    Ground floor retail spaces available in Rock Hill's Riverwalk.

    829 Terrace Park, Rock Hill, SC
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    New Retail/Medical Building For Lease
    Contact for pricing
    1,694 SF

    New Retail/Medical Building For Lease

    New construction retail/medical building with drive-thru available for lease.

    1530 Alexander Love Hwy E, York, SC
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    Medical Office Space For Rent
    $28 SF/Yr
    60,000 SF

    Medical Office Space For Rent

    Medical office space available in new 60,000 SF building.

    986 Wellness Wy, Fort Mill, SC 29715
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    Class A Medical/Office Development
    Contact for pricing
    60,000 SF

    Class A Medical/Office Development

    New medical/office development in Edgewater Corporate Park. Leasing now!

    1170 Edgewater Pkwy, Fort Mill, SC 29707
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    Based on your search, we've compiled 23 Potential Opportunities for your consideration. Besides 12 Active listings in York County, SC, we suggest exploring alternatives. Similar 7 Properties for Sales.

    Similar Spaces for Sale in York County, SC

    Consider Similar Space for Sale. We found 7 Spaces matching your search parameters.

    Versatile Commercial Property in Rock Hill
    $1,000,000
    10,479 SF
    Versatile Commercial Property in Rock Hill

    10,479 SF commercial property suitable for various uses.

    166 Dotson Street, Rock Hill, SC 29732

    View details
    Rock Hill Office Condo
    Contact for pricing
    6,165 SF
    Rock Hill Office Condo

    Office condo in high-demographic area, Rock Hill, South Carolina.

    1033 Bayshore Dr Suite B, Rock Hill, SC 29732

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    Freestanding Office Building in Rock Hill
    $1,795,000
    7,246 SF
    Freestanding Office Building in Rock Hill

    7,246 SF commercial building in high-traffic Rock Hill corridor.

    1601 Ebenezer Road, Rock Hill, SC 29732

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    Herlong Avenue Office/Retail Space
    Contact for pricing
    4,827 SF
    Herlong Avenue Office/Retail Space

    Divisible office/retail space across from Piedmont Medical Center.

    197 South Herlong Avenue, Rock Hill, SC 29732

    View details
    Lake Wylie Professional Office Condos
    $1,225,000
    3,500 SF
    Lake Wylie Professional Office Condos

    Professional/Medical office condos in Lake Wylie, 3500 SF total.

    252 Latitude Lane Suites 104, 105, & 106, Lake Wylie, SC 29710

    View details
    Medical Office Condo For Sale
    $495,000
    2,319 SF
    Medical Office Condo For Sale

    Medical office condo located on Piedmont Medical Center campus.

    200 S. Herlong Avenue # H, Rock Hill, SC 29732

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    Medical Office Near Hospital
    $429,000
    2,189 SF
    Medical Office Near Hospital

    Move-in ready medical office space near Piedmont Medical Center.

    744 Arden Ln, Rock Hill, SC 29730

    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Prime Development Opportunity in Greenville
    Contact for pricing

    Prime Development Opportunity in Greenville

    1.27 acre interstate-visible land for ground lease or build-to-suit.

    39 Airpark Ct, Greenville, SC 29607
    View details
    Prime Commercial Lot For Rent
    $7,500/Mo

    Prime Commercial Lot For Rent

    0.66 acre commercial lot with high visibility.

    Tift Avenue N, Tifton, GA 31794
    View details
    Prime Lexington Outlot Opportunity
    Contact for pricing

    Prime Lexington Outlot Opportunity

    Outlot for ground lease or build-to-suit in South Lexington.

    3330 Partner Place, Lexington, KY 40503
    View details
    Beaumont Centre Outparcel Opportunity
    Contact for pricing

    Beaumont Centre Outparcel Opportunity

    Outparcel opportunity in established shopping center for ground lease.

    3199 Beaumont Centre Circle, Lexington, KY 40513
    View details

    York County, SC Medical Office Space Leasing Opportunities Market Analysis

    Explore Medical Office Space leasing options in York County, SC with 12 listings featured on our commercial real estate exchange. The current inventory includes 63,649 square feet of properties with an estimated lease value of $56 SF/Yr.

    Estimated lease rates for Medical Office Space in York County, SC begin at $28 SF/Yr, with an average of $28 SF/Yr and extend to $28 SF/Yr.
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    Browse Medical Office Space for Lease Near York, SC

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