Medical Space

York County, SC Medical Office Space for Lease

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15 properties
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Freestanding Single-Story Office Building
Updated: Jul 30
Freestanding Single-Story Office Building

500 Lakeshore Pkwy, Rock Hill, SC 29730

Contact for pricing
6,560 sqft 1.18 AC lot
±6,560‑square‑foot freestanding office building on approximately 1.18 acres
Single‑story layout with private offices, reception, waiting areas, conference space, and workstations
Plumbing access in many offices supports medical office use
Lake frontage and walking trails within a professionally maintained business‑park setting
Ample on‑site parking
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Medical Office Space with Private Offices
Updated: Jun 8
Medical Office Space with Private Offices

1721 Ebenezer Rd, Rock Hill, SC 29732

Contact for pricing
2,588 sqft
Approximately 2,588 SF medical office condo
Seven private offices plus waiting and break areas
Second‑floor location within an office complex
Currently configured for a psychiatric practice
Located in front of Piedmont Medical Center
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Mixed-Use Retail and Office Space
Mixed-Use Retail and Office Space

343 Technology Center Way, Rock Hill, SC 29730

$23 SF/Yr

Retail and creative office space at a large live-work-play redevelopment in Rock Hill’s University Center.

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Flexible Medical Office Suite
Flexible Medical Office Suite

40 Ross Cannon St, York, SC 29745

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10,400 sqft

Medical office space with flexible suite configurations and prior assisted living use, sized at 10,400 SF.

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Hospital-Anchored Medical Office Building
Hospital-Anchored Medical Office Building

986 Wellness Way, Fort Mill, SC 29715

$33 SF/Yr

Three-story medical outpatient building with an enclosed walkway connection to Fort Mill Hospital–Piedmont Medical Center.

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Medical Office with Vault
Medical Office with Vault

1356 Filbert Hwy, York, SC 29745

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2,352 sqft

A masonry property offers a retained vault and a metal roof installed in 2024.

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Spacious Office and Medical Suite
Spacious Office and Medical Suite

345 Patricia Lane, Fort Mill, SC 29708

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8,988 sqft

8,988 SF professional office/medical suite in Fort Mill, SC.

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Medical Office on Oakland Avenue
Medical Office on Oakland Avenue

356 Oakland Avenue, Rock Hill, SC 29732

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3,600 sqft

3,600 SF medical office space for lease in Rock Hill.

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Rock Hill Medical/Office Suites
Rock Hill Medical/Office Suites

420 S Herlong Ave, Rock Hill, SC 29732

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2,100 sqft

Medical/office suites in established Rock Hill medical complex for rent.

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Medical Office Suite
Medical Office Suite

548 Nautical Dr Suite 202, Lake Wylie, SC 29710

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The space has a flexible configuration suited to medical and related professional uses.

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Medical/Professional Office Space Available
Medical/Professional Office Space Available

235 S. Herlong Avenue, Rock Hill, SC 29732

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1,200 sqft

Office space with frontage near Piedmont Medical Center.

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Flexible Medical Office Suites
Flexible Medical Office Suites

42 Ross Cannon St, York, SC 29745

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Multi-use office suites are available in flexible layouts for medical, professional office, or daycare users.

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Medical Office Space For Lease
Medical Office Space For Lease

1000 Wellness Way, Fort Mill, SC 29715

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Medical office space available for lease at 1000 Wellness Way in Fort Mill, SC.

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Medical Office Space with 11 Treatment Rooms
Medical Office Space with 11 Treatment Rooms

1334 Ebenezer Rd, Rock Hill, SC 29732

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4,135 sqft

Free-standing medical office with 11 treatment rooms, training room, and parking for 24 plus two handicap spaces.

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Corner End-Unit Office Space
Corner End-Unit Office Space

1180 Stonecrest Blvd, Tega Cay, SC 29708

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1,617 sqft

Second-generation space with upgraded finishes suits professional or medical use.

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Based on your search, we've compiled 32 Potential Opportunities for your consideration. Besides 15 Active listings in York County, SC, we suggest exploring alternatives. Similar 17 Properties for Sales.

Similar Spaces for Sale in York County, SC

Consider Similar Space for Sale. We found 17 Spaces matching your search parameters.

Fully Leased Medical Office Building
Fully Leased Medical Office Building

1665 Herlong Ct, Rock Hill, SC 29732

$1,550,000
6,514 sqft

Office building is fully leased, situated across from Piedmont Medical Center.

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Freestanding Office Building with Corner Site
Freestanding Office Building with Corner Site

362 Oakland Ave, Rock Hill, SC 29730

$600,000
1,500 sqft

Freestanding office building with a corner position and convenient access at a signalized intersection.

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Versatile Commercial Property in Rock Hill
Versatile Commercial Property in Rock Hill

166 Dotson St, Rock Hill, SC 29732

$1,000,000
10,479 sqft 1.24 AC lot

10,479 SF commercial property suitable for various uses.

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Second-Floor Medical Office Space
Second-Floor Medical Office Space

1721 Ebenezer Rd, Rock Hill, SC 29732

$4,932,277
11,874 sqft

Office condo with seven private offices, a waiting area, and break space.

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Freestanding Medical Office Building
Freestanding Medical Office Building

1601 Ebenezer Rd, Rock Hill, SC 29732

Contact for pricing
7,849 sqft 0.71 AC lot

All-brick building on a corner lot with 26 private rooms and a two-entry parking lot with 42 spaces.

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Freestanding Office Building
Freestanding Office Building

500 Lakeshore Parkway, Rock Hill, SC 29730

Contact for pricing
6,560 sqft 1.18 AC lot

Single-story layout includes private offices, reception areas, conference space, workstations, and on-site parking.

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Medical Office Facility
Medical Office Facility

166 Dotson Street, Rock Hill, SC 29732

$1,000,000
1.24 AC lot

The property includes on-site parking and GC zoning.

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Leased Medical Office Building with Ground Lease
Leased Medical Office Building with Ground Lease

245-1665 Herlong Ct, Rock Hill, SC 29732

Contact for pricing
9,572 sqft

Fully leased medical office building with a Truist Bank ground lease, positioned across from a regional medical center.

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Multi-Use Office Suites
Multi-Use Office Suites

40 Ross Cannon St Bldg. 3, York, SC 29745

Contact for pricing
10,400 sqft

Flexible office and medical suites are available, with sizes from about 2,000 to 10,400 SF.

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York County, SC Medical Office Space Market Trends and Statistics

Explore Medical Office Space leasing options in York County, SC with 15 listings featured on our commercial real estate exchange. The current inventory includes 43,540 square feet of properties with an estimated lease value of $56.

Estimated lease rates for Medical Office Space in York County, SC begin at $23 SF/Yr, with an average of $28 SF/Yr and extend to $33 SF/Yr.
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