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    York County, SC Medical Office Space for Lease

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    16 properties
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    Freestanding Single-Story Office Building
    Updated: Jul 30
    Freestanding Single-Story Office Building

    500 Lakeshore Pkwy, Rock Hill, SC 29730

    Contact for pricing
    6,560 sqft 1.18 AC lot
    ±6,560‑square‑foot freestanding office building on approximately 1.18 acres
    Single‑story layout with private offices, reception, waiting areas, conference space, and workstations
    Plumbing access in many offices supports medical office use
    Lake frontage and walking trails within a professionally maintained business‑park setting
    Ample on‑site parking
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    Flexible Medical Office Suites
    Updated: May 22
    Flexible Medical Office Suites

    42 Ross Cannon St, York, SC 29745

    Contact for pricing
    10,400 sqft
    Multi‑use office suites available for lease in York, SC
    Suites range from approximately 2,000 SF up to 10,400 SF
    Flexible layouts suitable for medical, professional office, or daycare users
    Convenient location with access to major thoroughfares
    Building was constructed in 1992
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    Mixed-Use Retail and Office Space
    Mixed-Use Retail and Office Space

    343 Technology Center Way, Rock Hill, SC 29730

    $23 SF/Yr

    Retail and creative office space at a large live-work-play redevelopment in Rock Hill’s University Center.

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    Open-Plan Office Suite
    Open-Plan Office Suite

    1741 Gold Hill Rd, Fort Mill, SC 29708

    Contact for pricing
    2,163 sqft 0.64 AC lot

    Flexible interior supports office, medical, wellness, studio, and fitness-oriented users within a mixed commercial center.

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    Flexible Medical Office Suite
    Flexible Medical Office Suite

    40 Ross Cannon St, York, SC 29745

    Contact for pricing
    10,400 sqft

    Medical office space with flexible suite configurations and prior assisted living use, sized at 10,400 SF.

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    Spacious Office and Medical Suite
    Spacious Office and Medical Suite

    345 Patricia Lane, Fort Mill, SC 29708

    Contact for pricing
    8,988 sqft

    8,988 SF professional office/medical suite in Fort Mill, SC.

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    Medical/Office Space in Rock Hill
    Medical/Office Space in Rock Hill

    410 S Herlong Ave, Rock Hill, SC 29732

    Contact for pricing
    2,598 sqft

    Established medical complex with adaptable suites near key locations.

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    Hospital-Anchored Medical Office Building
    Hospital-Anchored Medical Office Building

    986 Wellness Way, Fort Mill, SC 29715

    Contact for pricing
    1,831 sqft

    Three-story medical outpatient building with an enclosed walkway connection to Fort Mill Hospital–Piedmont Medical Center.

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    Medical Office on Oakland Avenue
    Medical Office on Oakland Avenue

    356 Oakland Avenue, Rock Hill, SC 29732

    Contact for pricing
    3,600 sqft

    3,600 SF medical office space for lease in Rock Hill.

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    Medical Office Space with Private Offices
    Medical Office Space with Private Offices

    1721 Ebenezer Rd, Rock Hill, SC 29732

    Contact for pricing
    2,588 sqft

    Second-floor office suite with a waiting area, seven private offices, and a break area in an established medical office complex.

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    Rock Hill Medical/Office Suites
    Rock Hill Medical/Office Suites

    420 S Herlong Ave, Rock Hill, SC 29732

    Contact for pricing
    2,100 sqft

    Medical/office suites in established Rock Hill medical complex for rent.

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    Medical/Professional Office Space Available
    Medical/Professional Office Space Available

    235 S. Herlong Avenue, Rock Hill, SC 29732

    Contact for pricing
    1,200 sqft

    Office space with frontage near Piedmont Medical Center.

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    Medical Office Space For Lease
    Medical Office Space For Lease

    1000 Wellness Way, Fort Mill, SC 29715

    Contact for pricing

    Medical office space available for lease at 1000 Wellness Way in Fort Mill, SC.

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    Medical Office Space with 11 Treatment Rooms
    Medical Office Space with 11 Treatment Rooms

    1334 Ebenezer Rd, Rock Hill, SC 29732

    Contact for pricing
    4,135 sqft

    Free-standing medical office with 11 treatment rooms, training room, and parking for 24 plus two handicap spaces.

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    Medical Office Space with Ample Parking
    Medical Office Space with Ample Parking

    1033 Bayshore Dr, Rock Hill, SC 29732

    Contact for pricing
    3,675 sqft

    Well-maintained medical office space with ample parking, about five minutes from I-77 off Celanese Rd.

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    Corner End-Unit Office Space
    Corner End-Unit Office Space

    1180 Stonecrest Blvd, Tega Cay, SC 29708

    Contact for pricing
    1,617 sqft

    Second-generation space with upgraded finishes suits professional or medical use.

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    Based on your search, we've compiled 34 Potential Opportunities for your consideration. Besides 16 Active listings in York County, SC, we suggest exploring alternatives. Similar 18 Properties for Sales.

    Similar Spaces for Sale in York County, SC

    Consider Similar Space for Sale. We found 18 Spaces matching your search parameters.

    Fully Leased Medical Office Building
    Fully Leased Medical Office Building

    1665 Herlong Ct, Rock Hill, SC 29732

    $1,650,000
    6,514 sqft

    Office building is fully leased, situated across from Piedmont Medical Center.

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    Versatile Commercial Property in Rock Hill
    Versatile Commercial Property in Rock Hill

    166 Dotson Street, Rock Hill, SC 29732

    $1,000,000
    10,479 sqft 1.24 AC lot

    10,479 SF commercial property suitable for various uses.

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    Freestanding Medical Office Building
    Freestanding Medical Office Building

    1601 Ebenezer Rd, Rock Hill, SC 29732

    Contact for pricing
    7,849 sqft 0.71 AC lot

    All-brick building on a corner lot with 26 private rooms and a two-entry parking lot with 42 spaces.

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    Freestanding Office Building
    Freestanding Office Building

    500 Lakeshore Pkwy, Rock Hill, SC 29730

    Contact for pricing
    6,560 sqft 1.18 AC lot

    Single-story layout includes private offices, reception areas, conference space, workstations, and on-site parking.

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    Leased Medical Office Building with Ground Lease
    Leased Medical Office Building with Ground Lease

    245-1665 Herlong Ct, Rock Hill, SC 29732

    Contact for pricing
    9,572 sqft

    Fully leased medical office building with a Truist Bank ground lease, positioned across from a regional medical center.

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    Multi-Use Office Suites
    Multi-Use Office Suites

    40 Ross Cannon St Bldg. 3, York, SC 29745

    Contact for pricing
    10,400 sqft

    Flexible office and medical suites are available, with sizes from about 2,000 to 10,400 SF.

    View details
    Herlong Avenue Office/Retail Space
    Herlong Avenue Office/Retail Space

    197 South Herlong Avenue, Rock Hill, SC 29732

    Contact for pricing
    4,827 sqft

    Divisible office/retail space across from Piedmont Medical Center.

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    Former Bank Office Building
    Former Bank Office Building

    1356 Filbert Hwy, York, SC 29745

    Contact for pricing
    2,474 sqft

    Sound masonry building with a new 2024 metal roof and a retained vault and door.

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    York County, SC Medical Office Space Market Trends and Statistics

    Explore Medical Office Space leasing options in York County, SC with 16 listings featured on our commercial real estate exchange. The current inventory includes 61,855 square feet of properties with an estimated lease value of $23.

    Estimated lease rates for Medical Office Space in York County, SC average $23 SF/Yr.
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