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North Charleston, SC Office Spaces for Lease

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Charleston, SC Summerville, SC Hanahan, SC Goose Creek, SC Ladson, SC Wando, SC Johns Island, SC Mount Pleasant, SC
93 properties
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Office Units in Brick Building
Updated: Aug 20
Office Units in Brick Building

4995 Lacross Rd, North Charleston, SC 29406

$3,047/Mo
6,158 sqft
Suite 1300 and Suite 1350 are currently available
One‑story office building containing ±45,255 SF
Direct visibility from I‑26
Contemporary brick exterior with architectural details
Surface parking with direct suite access
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Medical Office and Wellness Space
Updated: Jul 14
Medical Office and Wellness Space

2409 Mall Dr, North Charleston, SC 29406

$8,333/Mo
8,333 sqft 1.21 AC lot
8,333‑SF commercial space with a flexible, reconfigurable interior layout
High‑ceiling open area for tenant customization based on operational needs
Located on 1.21 acres with ample free surface parking
Positioned along a highly trafficked commercial corridor in North Charleston
Within walking distance of the future Roper Hospital System campus (est. delivery in three years)
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Three Office Suites with Atrium
Three Office Suites with Atrium

7301 Rivers Ave, North Charleston, SC 29406

$1,210/Mo
2,591 sqft

Two-story brick property offers interstate access, an atrium lobby, and proximity to restaurants, shopping, and banks.

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Renovated Flex Space
Renovated Flex Space

3294 Ashley Phosphate Rd, North Charleston, SC 29418

$465/Mo
465 sqft

Recently renovated commercial space with paved, surface-level parking and frontage along Ashley Phosphate Road.

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Newly Renovated Office Building
Newly Renovated Office Building

3265 N Carolina Ave, North Charleston, SC 29405

$2,400/Mo
2,400 sqft

Newly renovated office building with ample on-site parking and convenient access to major roads.

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Renovated Office Units
Renovated Office Units

7410 Northside Dr, North Charleston, SC 29420

$2,251-$14,188/Mo
2,218 sqft

Updated office space with refreshed common areas, parking, and convenient interstate access.

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Office Units
Office Units

1505 King Street Ext, North Charleston, SC 29405

$39 SF/Yr
3,500 sqft

Office space is offered for rent at a North Charleston property with documented ties to prior industrial users.

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Renovated Office/Retail Suite
Renovated Office/Retail Suite

8316 Rivers Ave, North Charleston, SC 29406

$24 SF/Yr
1,950 sqft

Move-in ready suite renovated in 2022 with lobby, private offices, break room, bathrooms, and strong frontage on Rivers Avenue.

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Class A Office Space Available
Class A Office Space Available

4401 Leeds Avenue, North Charleston, SC 29405

$34.50 SF/Yr
8,452 sqft

Four-story, 102,024 SF Class A office building for lease.

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Park Circle Freestanding Retail Building
Park Circle Freestanding Retail Building

1086 East Montague Avenue, North Charleston, SC 29405

$35 SF/Yr
1,800 sqft

Freestanding building in Park Circle, ideal for retail or office.

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Renovated Industrial Space Available
Renovated Industrial Space Available

7391 Pepperdam Avenue, North Charleston, SC 29418

$10 SF/Yr
96,811 sqft

Recently renovated industrial suites available for lease in North Charleston.

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Fully Serviced Business Solutions at Faber Center. Contact us today to book a tour!
Fully Serviced Business Solutions at Faber Center. Contact us today to book a tour!

4000 Faber Place Dr, Unit 300, North Charleston, SC 29405

16 available spaces from 11 to 2,045 sqft
$129-$22,234/Mo per office

Flexible workspace in Faber Center. Book a tour & get info

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Retail Office Restaurant Space
Retail Office Restaurant Space

7027 Dorchester Rd, North Charleston, SC 29418

$1,500/Mo

Leasable commercial space on Dorchester Road with modern amenities and ample parking for customers.

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Full-Floor Medical Office Suite
Full-Floor Medical Office Suite

4969 Centre Pointe Drive # 100, North Charleston, SC 29418

Contact for pricing
10,363 sqft

Full-floor medical office space at Oaks at Centre Pointe with expansion flexibility for growing practices.

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Flex Space with Roll-Up Door
Flex Space with Roll-Up Door

2409 Mall Drive # B, North Charleston, SC 29406

Contact for pricing
8,333 sqft 1.21 AC lot

Customizable conditioned flex suite with multiple restrooms, high ceilings, and ample free parking along a high-traffic corridor.

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First-Generation Office and Medical Suites
First-Generation Office and Medical Suites

8471 Dorchester Road, North Charleston, SC 29420

Contact for pricing
6,500 sqft

Flexible, suite-divisible two-story space on a busy commercial corridor with landlord-provided shell build-out.

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Freestanding Warehouse Flex Building
Freestanding Warehouse Flex Building

2960 Rivers Avenue, North Charleston, SC 29405

Contact for pricing
5,000 sqft 0.22 AC lot

Freestanding warehouse flex with office, rollup doors, and a laydown yard on a hard-corner for strong visibility.

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Move-In Ready Office Sublease
Move-In Ready Office Sublease

4289 Spruill Ave, North Charleston, SC 29405

Contact for pricing
4,896 sqft

Sublease space totaling 4,896 SF with eight private offices, open collaborative area, and a kitchenette.

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North Charleston Office Building For Sale
North Charleston Office Building For Sale

2170 Ashley Phosphate Road, North Charleston, SC 29406

$20.50 SF/Yr
67,067 sqft

Second-generation office space with open and private workspaces available.

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Industrial Service Facility with Drive Doors
Industrial Service Facility with Drive Doors

3265 Associate Drive, North Charleston, SC 29418

Contact for pricing
13,000 sqft 6.58 AC lot

Industrial service facility offering warehouse and office space with multiple drive-through and drive-in doors, supported by outdoor yard storage.

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Class A Office Building
Class A Office Building

3875 Faber Place Drive, North Charleston, SC 29405

$25 SF/Yr
15,224 sqft

Class A office building with common area upgrades and efficient layouts.

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Renovated Office Building Suites
Renovated Office Building Suites

4975 Lacross Road, North Charleston, SC 29406

Contact for pricing
1,040 sqft

Renovated three-story office building with remaining suites, plus free on-site surface parking.

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Office Units with Land
Office Units with Land

3625 Cheatham St, North Charleston, SC 29418

$5,000/Mo

Office units with accompanying land offer flexible commercial space near Tanger Mall, the airport, and Dorchester Road.

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Renovated Flex Space with Drive-In Doors
Renovated Flex Space with Drive-In Doors

4540 Rivers Ave, North Charleston, SC 29405

Contact for pricing
2,733 sqft

Two suites offer office improvements, storefront access, and multiple drive-in doors.

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North Charleston, SC Office Spaces Lease Rates & Market Statistics

Explore 93 Office Spaces for lease in North Charleston, SC on Realmo, a commercial real estate exchange covering the North Charleston area. The current inventory totals 550,416 square feet of properties — an average of ~5,900 SF per listing.

Office Spaces lease rates in North Charleston range from $5.60 SF/Yr at the entry level to $39 SF/Yr at the top of the market, averaging $21.64 SF/Yr. That's a 7x spread between entry-level and premium space, making side-by-side comparison of asking rents and lease terms essential. At $21.64 SF/Yr, the local average runs 7% below South Carolina's state average of $23.14 SF/Yr.

Within Charleston County, most North Charleston office spaces listings are located in and around Charleston, with additional options across the city. By space type, the market includes 71 office units, 16 office buildings and 12 medical office space listings — medical office space options typically offer the lowest entry point, while office buildings command the highest rates.

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