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North Charleston, SC Office Spaces for Lease

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52 properties
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SC, North Charleston - Aviation Center
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Medical Office and Wellness Space
Updated: Jul 14
Medical Office and Wellness Space

2409 Mall Dr, North Charleston, SC 29406

$8,333/Mo
8,333 sqft $12 SF/Yr
8,333‑SF commercial space with a flexible, reconfigurable interior layout
High‑ceiling open area for tenant customization based on operational needs
Located on 1.21 acres with ample free surface parking
Positioned along a highly trafficked commercial corridor in North Charleston
Within walking distance of the future Roper Hospital System campus (est. delivery in three years)
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Faber Center
Updated: Feb 19
Faber Center

4000 Faber Place Dr, Unit 300, North Charleston, SC 29405

$129-$22,234/Mo
11-2,045 sqft
Be part of a vibrant coworking community with dedicated desk or hot desking options in thousands of idyllic locations across the globe
Grow in a modern workplace with the added advantage of a benefits program offering exclusive discounts and bespoke procurement support
Access Regus' network of workspaces and business lounges as often as you need and take advantage of their exclusive benefits
Impress clients, hold memorable workshops, and deliver a winning pitch in Regus' meeting spaces, fully equipped for gatherings of any size
Collaborate with like‑minded professionals and enjoy regular networking and community events with a Regus membership
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Class A Office Space Available
Class A Office Space Available

4401 Leeds Avenue, North Charleston, SC 29405

$34.50 SF/Yr
8,452 sqft $24,299/Mo

Four-story, 102,024 SF Class A office building for lease.

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Dorchester Pavilion
Dorchester Pavilion

8636 Dorchester Rd, North Charleston, SC 29420

$30 SF/Yr
1,400 sqft $3,500/Mo

Charleston, SC Restaurant/Medical/Retail Space

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Office Space Near Government Buildings
Office Space Near Government Buildings

3844 Leeds Ave, North Charleston, SC 29405

$2,000/Mo
1,244 sqft $19.29 SF/Yr

Office space with high visibility and convenient highway access.

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Park Circle Freestanding Retail Building
Park Circle Freestanding Retail Building

1086 East Montague Avenue, North Charleston, SC 29405

$35 SF/Yr
1,800 sqft $5,250/Mo

Freestanding building in Park Circle, ideal for retail or office.

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Renovated Office Space Available
Renovated Office Space Available

6296 Rivers Ave, North Charleston, SC

$22 SF/Yr
1,791 sqft $3,283/Mo

Recently renovated office space in a convenient North Charleston location.

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Rivers Avenue Office/Retail Space
Rivers Avenue Office/Retail Space

4762 Rivers Ave, North Charleston, SC 29405

$1,100/Mo
350 sqft $37.71 SF/Yr

350 SF office/retail space in North Charleston available for rent.

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Flex Space on Retail Corridor
Flex Space on Retail Corridor

8120 Windsor Hill Blvd, North Charleston, SC

$15 SF/Yr
10,000 sqft $12,500/Mo

Flex space suitable for office, retail, or industrial use.

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Renovated Industrial Space Available
Renovated Industrial Space Available

7391 Pepperdam Avenue, North Charleston, SC 29418

$9.75 SF/Yr
96,811 sqft $78,658/Mo

Recently renovated industrial suites available for lease in North Charleston.

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North Charleston Office Space Available
North Charleston Office Space Available

2070 Northbrook Blvd, North Charleston, SC

$19.95 SF/Yr
1,664 sqft $2,766/Mo

Office space for rent in North Rivers Business Center.

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North Charleston Office Building For Sale
North Charleston Office Building For Sale

2170 Ashley Phosphate Road, North Charleston, SC 29406

$20.50 SF/Yr
67,067 sqft $114,572/Mo

Second-generation office space with open and private workspaces available.

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Class A Office Building
Class A Office Building

3875 Faber Place Drive, North Charleston, SC 29405

$25 SF/Yr
15,224 sqft $31,716/Mo

Class A office building with common area upgrades and efficient layouts.

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Flex Office Suite with Conference Room
Flex Office Suite with Conference Room

3125 Ashley Phosphate Road # 124, North Charleston, SC 29406

Contact for pricing
824 sqft

Suite 124 offers an office reception, two offices, a conference room, and one bathroom in a one-story flex complex.

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Full-Floor Medical Office Suite
Full-Floor Medical Office Suite

4969 Centre Pointe Drive # 100, North Charleston, SC 29418

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10,363 sqft

Full-floor medical office space at Oaks at Centre Pointe with expansion flexibility for growing practices.

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First-Generation Office and Medical Suites
First-Generation Office and Medical Suites

8471 Dorchester Road, North Charleston, SC 29420

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6,500 sqft

Flexible, suite-divisible two-story space on a busy commercial corridor with landlord-provided shell build-out.

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Renovated Flex Building with Warehouse
Renovated Flex Building with Warehouse

5513 Rivers Avenue, North Charleston, SC 29406

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3,048 sqft

Renovated office/showroom with hardwood floors plus rear warehouse access via two roll-up doors.

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Standalone Industrial Flex Building
Standalone Industrial Flex Building

7268 Peppermill Parkway, North Charleston, SC 29418

Contact for pricing
4,000 sqft

Standalone industrial flex building with fenced laydown yard, office space, warehouse area, and drive-in access.

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Flex Space with Adjustable Open Plan
Flex Space with Adjustable Open Plan

2011 Carver Ave, North Charleston, SC 29405

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1,200 sqft

Recently renovated flex suite offers a flexible layout with natural light, plus a kitchen and private bathroom.

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Freestanding Warehouse Flex Building
Freestanding Warehouse Flex Building

2960 Rivers Avenue, North Charleston, SC 29405

Contact for pricing
5,000 sqft

Freestanding warehouse flex with office, rollup doors, and a laydown yard on a hard-corner for strong visibility.

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Flex Space with Secure Yard
Flex Space with Secure Yard

1959 Jacksonville Rd, North Charleston, SC 29405

Contact for pricing
1,810 sqft

Newly renovated office-warehouse layout with secure yard access for operations needing controlled storage and admin space.

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Medical Office Suite
Medical Office Suite

3210 Landmark Drive, North Charleston, SC 29418

Contact for pricing
1,880 sqft

Move-in ready OB-GYN medical space with strong visibility, signage, and ample parking for healthcare practices.

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Office/Warehouse Flex Suite
Office/Warehouse Flex Suite

2235 Technical Parkway, North Charleston, SC 29406

Contact for pricing
1,500 sqft

Versatile office and warehouse space in a business park setting, ideal for operations needing both work area and storage.

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Class A Office Space
Class A Office Space

4390 Belle Oaks Drive, North Charleston, SC 29405

$27 SF/Yr
45,644 sqft $102,699/Mo

Class A office building with convenient highway access.

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North Charleston, SC Office Spaces Market Trends and Statistics

Explore Office Spaces leasing options in North Charleston, SC with 52 listings featured on our commercial real estate exchange. The current inventory includes 429,089 square feet of properties with an estimated lease value of $2,890,756.

Estimated lease rates for Office Spaces in North Charleston, SC begin at $9.75 SF/Yr, with an average of $115,630 and extend to $2,890,000.
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