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    Greenville, SC Charleston, SC Spartanburg, SC
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    South Carolina Office Properties & Spaces for Lease

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    Showing 24 of 1,154 results
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    Commercial Space on Sea Island Parkway
    $2,750 /Mo
    2,178 SF

    Commercial Space on Sea Island Parkway

    Commercial space with high visibility near Fripp and Hunting Islands.
    2123 Sea Island Pkwy, Saint Helena Island, SC 29920
    View details
    Harbor Island Commercial Office Space
    $450 /Mo
    436 SF

    Harbor Island Commercial Office Space

    Office space available on Harbor Island, excellent visibility and access.
    2123 Sea Island Pkwy, Saint Helena Island, SC 29920
    View details
    Lady's Island Multi-Use Space
    $750 /Mo

    Lady's Island Multi-Use Space

    Multi-use commercial space available on Lady's Island, SC.
    9 Rue Du Bois, Ladys Island, SC 29907
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    Prime Beaufort Office Space Available
    $800 /Mo
    6,970 SF

    Prime Beaufort Office Space Available

    100 SF office space in a prime, central Beaufort location.
    205 Ribaut Rd, Beaufort, SC 29902
    View details
    Beaufort Office Space For Rent
    $800 /Mo
    6,970 SF

    Beaufort Office Space For Rent

    Office space in a prime, central Beaufort location.
    205 Ribaut Rd, Beaufort, SC 29902
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    Beaufort Office Space For Rent
    $1,300 /Mo
    6,970 SF

    Beaufort Office Space For Rent

    240 SF office space in a prime, central Beaufort location.
    205 Ribaut Rd, Beaufort, SC 29902
    View details
    North Augusta Commercial Building For Lease
    $16 SF/Yr
    7,100 SF

    North Augusta Commercial Building For Lease

    Office and warehouse spaces available in North Augusta, South Carolina.
    1305 Georgia Ave, North Augusta, SC 29841
    View details
    Medical Office Space For Lease
    $1,900 /Mo

    Medical Office Space For Lease

    2,500 SF medical office space, convenient location, available now.
    11382 N Jacob Smart Blvd, Ridgeland, SC 29936
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    Office Space in Hampton, SC
    $800 /Mo
    871 SF

    Office Space in Hampton, SC

    Two offices with an open area available for rent.
    12 Mulberry St E, Hampton, SC 29924
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    Renovated Retail/Office Space in Beaufort
    $1,833 /Mo
    3,485 SF

    Renovated Retail/Office Space in Beaufort

    Historic Beaufort location ideal for retail, office, or service businesses.
    609 Carteret St, Beaufort, SC 29902
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    Commercial Space in Beaufort, SC
    $30 SF/Yr

    Commercial Space in Beaufort, SC

    New construction commercial space available for rent in Beaufort.
    960 Ribaut Rd, Beaufort, SC 29902
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    Salon Suite in Port Royal
    $625 /Mo

    Salon Suite in Port Royal

    80 sq ft salon suite available for rent.
    2206 Mossy Oaks Rd, Port Royal, SC 29935
    View details
    New Custom-Built Office Suites
    $1,500 /Mo
    3,049 SF

    New Custom-Built Office Suites

    Pre-leasing custom office suites with private entrances, available Q2 2026.
    101 Ladys Is Cmns, Ladys Island, SC 29907
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    Renovated Office Space Available
    $1,900 /Mo
    436 SF

    Renovated Office Space Available

    Newly renovated 650 SF office space in Lady's Island.
    1 Merchants Ln, Ladys Island, SC 29907
    View details
    Commercial Space on Harbor Island
    $1,200 /Mo
    436 SF

    Commercial Space on Harbor Island

    Commercial property with high visibility near Fripp and Hunting Islands.
    2123 Sea Is Pkwy Unit, Saint Helena Island, SC 29920
    View details
    Salon Suite in Port Royal
    $750 /Mo

    Salon Suite in Port Royal

    Salon suite with utilities and Wi-Fi included in rent.
    2206 Mossy Oaks Rd, Port Royal, SC 29935
    View details
    Office/Storage Space with Land
    $1,000 /Mo
    1,307 SF

    Office/Storage Space with Land

    Commercial office/storage space with ample land in Beaufort, SC.
    40 Shanklin Rd, Beaufort, SC 29906
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    Renovated Retail/Office Space in Beaufort
    $2,736 /Mo

    Renovated Retail/Office Space in Beaufort

    Historic Beaufort location, renovated space, ideal for retail or office.
    609 Carteret St, Beaufort, SC 29902
    View details
    Prime Location Office/Retail Space
    $31 SF/Yr

    Prime Location Office/Retail Space

    New office/retail space near Lake Keowee, customizable to tenant needs.
    1217 Stamp Creek Rd, Salem, SC 29676
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    Move-in Ready Office Space
    $2,200 /Mo
    15,246 SF

    Move-in Ready Office Space

    Well-maintained office space in established professional park, ready for occupancy.
    111 N Earle St, Walhalla, SC 29691
    View details
    Seneca Office Space For Lease
    $1,500 /Mo
    26,136 SF

    Seneca Office Space For Lease

    Two-level office building suitable for various businesses, near Clemson.
    865 Old Clemson Hwy, Seneca, SC 29678
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    Professional Office Space in Seneca
    $2,200 /Mo
    30,056 SF

    Professional Office Space in Seneca

    Office space near downtown Seneca with utilities included.
    815 Robin Dr Unit, Seneca, SC 29678
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    Office Space Near Clemson
    $4,000 /Mo
    26,136 SF

    Office Space Near Clemson

    Two-level office building suitable for various businesses, near Clemson.
    865 Old Clemson Hwy, Seneca, SC 29678
    View details
    Office Space in Sumter, SC
    $250 SF/Yr
    161 SF

    Office Space in Sumter, SC

    161 sq ft interior office space available for rent.
    698-K Bultman Dr, Sumter, SC 29150
    View details
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