South Carolina Commercial Real Estate for Lease

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Greenville, SC Columbia, SC Myrtle Beach, SC Charleston, SC North Charleston, SC Spartanburg, SC Rock Hill, SC Conway, SC
3,004 properties
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Two-Unit Retail Space
Two-Unit Retail Space

10729 Ocean Highway, Pawleys Island, SC 29585

$5,349/Mo
2,006 sqft

The paired suites occupy a corner position within a dining and shopping center.

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Storefront Property with Courtyard
Storefront Property with Courtyard

1623 Highway 501, Myrtle Beach, SC 29577

$10,000/Mo
6,700 sqft

The property includes a full kitchen and a private courtyard for indoor and outdoor commercial space.

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Multi-Bay Flex Space
Multi-Bay Flex Space

374 Darlington St., Florence, SC 29501

$3,800/Mo
11,390 sqft  Built 1951

Open work areas are complemented by front office space and restrooms.

Multiple bay doors  Dedicated office space  Restrooms
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One-Room Office Unit
One-Room Office Unit

918 Houndslake Drive, Aiken, SC 29803

$534/Mo
1 person  120 sqft  Built 1979  2.07 acres

Utilities and shared internet are included, with common reception areas and a lower-level kitchen.

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Brewery/Restaurant Space with Patio
Brewery/Restaurant Space with Patio

250 Mill St, Taylors, SC 29687

$9 SF/Yr
8,000 sqft

Open-plan hospitality space with a prep kitchen, dedicated restrooms, storage, loading facilities, and an outdoor deck.

400 parking spaces
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Modern Medical Office Space
Modern Medical Office Space

391 Serpentine Drive, Spartanburg, SC 29303

$1,156/Mo
4,387 sqft

Modern medical suites with patient-care areas, elevator access, on-site parking, and proximity to Spartanburg Regional Medical Hospital.

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New Construction Retail Space
New Construction Retail Space

Garden City Connector, Murrells Inlet, SC 29576

$12,611/Mo
6,580 sqft

Multi-unit retail development with shared parking, signage options, and cold dark shell delivery.

72 parking spaces
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Medical Office Space with Clinical Upfit
Medical Office Space with Clinical Upfit

2320 Cosgrove Avenue, North Charleston, SC 29405

Triple net (NNN)
$24 SF/Yr
4,935 sqft  0.31 acres

Plumbing and medical connections remain throughout the building, alongside on-site parking.

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Flex Building with Showroom
Flex Building with Showroom

6006 Two Notch Rd, Columbia, SC 29223

$7.50 SF/Yr
9,700 sqft  25 ft clear  1 drive-in  Built 1976

Lease space combines open retail presentation areas with warehouse capacity, offices, storage, and customer parking.

Two offices  Kitchen area  Additional storage  New HVAC
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Renovated Freestanding Office Building
Renovated Freestanding Office Building

812 W Whitner Street, Anderson, SC 29624

$3,500/Mo
17–29 people  4,430 sqft

A converted historic residence offers private office rooms, a renovated kitchen, and on-site parking.

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Single-Story Professional Office Units
Single-Story Professional Office Units

212 Newberry Street NW, Aiken, SC 29801

Triple net (NNN)
$4,800/Mo
12–21 people  3,214 sqft  Built 1975

Configured for professional users with private rooms, meeting space, support areas, and on-site parking.

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Turnkey Restaurant Space
Turnkey Restaurant Space

902 Gervais Street, Columbia, SC 29201

$4,767/Mo
4,767 sqft

Restaurant suite with mezzanine space, street frontage, available parking, and established dining and entertainment surroundings.

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Flex Space with Showroom
Flex Space with Showroom

403 Mauldin Rd, Greenville, SC 29605

$12 SF/Yr
10,000 sqft

A warehouse-oriented flex property includes dedicated office and showroom space for combined operational and customer-facing use.

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Retail Space with Wraparound Porch
Retail Space with Wraparound Porch

10880 Ocean Highway, Pawleys Island, SC 29585

$3,092/Mo
1,855 sqft

A covered outdoor area faces a pond at this freestanding space in The Hammock Shops Village.

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In-Line Retail Suite
In-Line Retail Suite

10729 Ocean Highway, Pawleys Island, SC 29585

$2,461/Mo
923 sqft

Unit B occupies the Ocean Highway and Professional Lane corner within a center anchored by two restaurants.

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Second-Floor Office Unit
Second-Floor Office Unit

870 Inlet Square Dr., Murrells Inlet, SC 29576

$1,450/Mo
4–8 people  1,246 sqft  0.59 acres

HC-zoned office space positioned near major commercial and recreational destinations in Murrells Inlet.

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Retail Showroom with Signage
Retail Showroom with Signage

146 Southport Road, Spartanburg, SC 29306

$14.95 SF/Yr
3,200 sqft  Built 1979
16,600 VPD

Retail space combines a customer-facing showroom with back-office and inventory areas for lease.

Monument signage
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Professional Office Suite
Professional Office Suite

4728 Jenn Dr., Myrtle Beach, SC 29577

$3,100/Mo
6–10 people  1,500 sqft  1.9 acres

Configured with private offices, a conference room, reception area, and shared restroom access.

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Multi-Suite Office Property
Multi-Suite Office Property

1013 Surf Pine Dr, Surfside Beach, SC 29575

$4,500/Mo
13–22 people  3,419 sqft  0.6 acres

Two-level commercial layout includes private offices, conference rooms, storage, and a fenced outdoor area.

20 parking spaces
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Office Suites with Conference Center
Office Suites with Conference Center

1301 Gervais St, Columbia, SC 29201

$1,065/Mo
49–81 people  12,284 sqft

Office and retail suites offer secure building access, parking, and shared tenant amenities in Columbia’s Central Business District.

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Restaurant with Outdoor Seating
Restaurant with Outdoor Seating

3916 Highway 17 Business, Murrells Inlet, SC 29576

$13,000/Mo
6,500 sqft

Existing kitchen, bar, and exterior dining space are configured for food-and-beverage service.

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New Medical Office Suites
New Medical Office Suites

5100 Highway 17, Murrells Inlet, SC 29576

$3,125/Mo
2,500 sqft

New construction with adaptable suite layouts, on-site parking, and direct exposure along a heavily traveled commercial corridor.

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Flex Space with Roll-Up Doors
Flex Space with Roll-Up Doors

2515 Two Notch Rd, Columbia, SC 29204

Community Improvement Cooperative Council
$4,000/Mo
5,000 sqft  15 ft clear  Built 1990  110 sqft office

Versatile flex property combining warehouse capacity with dedicated office space and roll-up loading access.

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Retail Space with On-Site Parking
Retail Space with On-Site Parking

515 East Bay Street, Charleston, SC 29403

$42 SF/Yr
2,609 sqft

The first-floor suite comes with four front parking spaces, with more parking available behind the building.

4 parking spaces
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