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    Simpsonville, SC Office Properties & Spaces for Lease

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    Columbia, SC Greenville, SC Charleston, SC
    16 results
    Simpsonville Office Suite for Rent
    $18 SF/Yr
    2,875 SF

    Simpsonville Office Suite for Rent

    419 Main St, Simpsonville, SC

    Office suite with ample parking and convenient highway access.

    • Convenient access to I‑385 & downtown Simpsonville
    • ±2,875 SF office suite with 8 spacious offices
    • ±50 parking spaces
    • Large reception/lobby and kitchenette
    • Zoned BL City of Simpsonville
    Updated: Nov 24, 2025
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    Simpsonville Flex Space Available
    $12 SF/Yr
    16,200 SF

    Simpsonville Flex Space Available

    501 Richardson Street |, Simpsonville, SC 29681

    Flex space available for lease near I-385 in Simpsonville.

    • Excellent Location: Minutes from Downtown Simpsonville and close to I‑385.
    • Flex Space: Features a combination of ±1,800 SF of office space and ±900 SF of warehouse space.
    • Fully Air Conditioned: Ensures a comfortable working environment.
    • Functional Layout: Includes six (6) offices and one (1) conference room.
    • Convenient Access: Located off W. Georgia Road, ±1.2 miles from I‑385.
    Updated: Sep 25, 2025
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    Simpsonville Office Space For Rent
    $14 SF/Yr
    3,150 SF

    Simpsonville Office Space For Rent

    Office space available for lease in Simpsonville, South Carolina.

    1027 South St, Simpsonville, SC
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    334,000 SF Office Building For Lease
    $19 SF/Yr

    334,000 SF Office Building For Lease

    334,000 SF Office Building For Lease

    300 South St, Simpsonville, SC 29681
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    334,000 SF Office Building For Lease
    $19 SF/Yr

    334,000 SF Office Building For Lease

    334,000 SF Office Building For Lease

    300 South St, Simpsonville, SC 29681
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    Simpsonville Flex Space For Rent
    Contact for pricing
    24,635 SF

    Simpsonville Flex Space For Rent

    Flex space featuring warehouses, shops, and office space available for lease.

    514 Palmetto Dr, Simpsonville, SC 29681
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    Simpsonville Office Space Available
    $19 SF/Yr
    12,463 SF

    Simpsonville Office Space Available

    Office space available for lease in Simpsonville, SC.

    100 Allawood Ct, Simpsonville, SC
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    Beck Plaza
    $15 SF/Yr

    Beck Plaza

    1,100 SF Retail Building

    1028 NE Main Street, Simpsonville, SC 29681
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    Beck Plaza
    $15 SF/Yr

    Beck Plaza

    1,100 SF Retail Building

    1028 NE Main Street, Simpsonville, SC 29681
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    Simpsonville Retail Space For Lease
    Contact for pricing
    7,500 SF

    Simpsonville Retail Space For Lease

    Up to 7,500 SF retail space in Simpsonville, SC.

    721 SE Main St, Simpsonville, SC 29681
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    Simpsonville Office Space For Rent
    $32 SF/Yr
    5,904 SF

    Simpsonville Office Space For Rent

    5,904 SF office space available for lease.

    220 Scuffletown Rd, Simpsonville, SC
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    0 Bridgeway
    Contact for pricing

    0 Bridgeway

    ±6,197 SF of office space availalble

    0 Bridgeway Simpsonville, SC 29681, Simpsonville, SC 29681
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    0 Bridgeway
    Contact for pricing

    0 Bridgeway

    ±6,197 SF of office space availalble

    0 Bridgeway Simpsonville, SC 29681, Simpsonville, SC 29681
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    Commercial Building For Rent
    Contact for pricing
    5,000 SF

    Commercial Building For Rent

    Commercial building for rent with showroom and office space.

    926 Fairview Rd, Simpsonville, SC 29680
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    Downtown Simpsonville New Construction Retail
    Contact for pricing

    Downtown Simpsonville New Construction Retail

    New construction retail and office space in downtown Simpsonville.

    114 E Curtis St, Simpsonville, SC 29681
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    Retail/Office Space Available
    Contact for pricing
    1,500 SF

    Retail/Office Space Available

    Retail and office space available for rent.

    505 SE Main St, Simpsonville, SC 29681
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    Based on your search, we've compiled 33 Potential Opportunities for your consideration. Besides 16 Active listings in Simpsonville, SC, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 9 Properties for Sales.

    Explore Office properties & Spaces for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Creative Office Space Available
    $6 SF/Yr

    Creative Office Space Available

    Creative office space for lease in Mauldin, South Carolina.

    11 Forrester Drive |, Mauldin, SC 29662
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    Global Network Workspace Available
    Contact for pricing

    Global Network Workspace Available

    Flexible workspace solutions with tailored options and global access.

    220 North Main Street Suite 500, Greenville, SC 29601
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    Creative Office Space Available
    Contact for pricing
    5,876 SF

    Creative Office Space Available

    Creative office space for lease in Mauldin, South Carolina.

    11 Forrester Dr, Mauldin, SC 29662
    View details
    Downtown Greenville Class A Office
    Contact for pricing

    Downtown Greenville Class A Office

    Class A office space available in downtown Greenville.

    220 N Main St, Greenville, SC 29601
    View details

    Explore Similar Spaces for Sale in Simpsonville, SC

    Consider Similar Space for Sale. We found 9 Spaces matching your search parameters.

    Professional Office Space in Simpsonville
    $425,000
    0.49 Acres

    Professional Office Space in Simpsonville

    Adaptable office space near downtown Simpsonville and Fairview Road.

    107 Hillcrest Avenue, Simpsonville, SC 29681
    View details
    Charming Updated Office in Simpsonville
    Contact for pricing
    0.37 Acres

    Charming Updated Office in Simpsonville

    Prime location in Historic Downtown Simpsonville with rustic charm.

    312 S Main Street, Simpsonville, SC 29681
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    Office Space in Simpsonville, SC
    Contact for pricing
    0.18 Acres

    Office Space in Simpsonville, SC

    Office property for sale in Simpsonville, South Carolina.

    131 SE Main Street, Simpsonville, SC 29681
    View details
    Professional Office Space in Simpsonville
    $425,000
    1,844 SF

    Professional Office Space in Simpsonville

    Adaptable 1,844 sq ft office near downtown Simpsonville.

    117 Hillcrest Avenue, Simpsonville, SC 29681
    View details
    Historic Mill Office Space Available
    Contact for pricing
    8,082 SF

    Historic Mill Office Space Available

    Office space in a renovated historic textile mill.

    300 S St, Simpsonville, SC
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    Main Street Commercial Opportunity
    $750,000
    1.42 Acres

    Main Street Commercial Opportunity

    Property with high visibility and development potential on 1.42 acres.

    1306 NE Main St, Simpsonville, SC
    View details
    Highway Frontage Property For Sale
    $550,000
    0.77 Acres

    Highway Frontage Property For Sale

    Versatile property with highway frontage, ideal for retail or office.

    1304 NE Main St, Simpsonville, SC
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    Versatile Commercial Property For Sale
    $725,000
    2,200 SF

    Versatile Commercial Property For Sale

    Adaptable commercial space with high visibility and convenient highway access.

    1306 NE Main St, Simpsonville, SC 29861
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Toccoa Commercial Lease Opportunity
    $1,500 /Mo
    306 SF

    Toccoa Commercial Lease Opportunity

    Prime commercial location in Toccoa, GA for lease.

    655 S Pond Street, Toccoa, GA 30577
    View details
    Land Lease Opportunity in Waxhaw
    $8,000 /Mo

    Land Lease Opportunity in Waxhaw

    5.341-acre commercial land for lease in a high-growth area.

    5325 Waxhaw Marvin Road, Waxhaw, NC 28173
    View details
    Commercial Land Near Interstate 40
    $499,900
    1,860 SF

    Commercial Land Near Interstate 40

    3.96 acres with high visibility near Interstate 40.

    310 Goose Creek Road, Dandridge, TN 37725
    View details
    Prime Commercial Land For Lease
    $285,000

    Prime Commercial Land For Lease

    3 acres of B-3 zoned land with city amenities.

    220 Silver Lake Road, Church Hill, TN 37642
    View details

    Simpsonville, SC Office properties & Spaces Leasing Opportunities Market Analysis

    Explore Office properties & Spaces leasing options in Simpsonville, SC with 16 listings featured on our commercial real estate exchange. The current inventory includes 1,100,064,240 square feet of properties with an estimated lease value of $58 SF/Yr.

    Estimated lease rates for Office properties & Spaces in Simpsonville, SC begin at $12 SF/Yr, with an average of $19 SF/Yr and extend to $32 SF/Yr.
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    Most Searched ZIP Codes in Simpsonville, SC

    • 29681
    • 29680

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