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    Simpsonville, SC
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    Simpsonville, SC Office Spaces for Lease

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    Greenville, SC Fountain Inn, SC Mauldin, SC
    14 results
    Historic Downtown Simpsonville Office Space
    $5,084/Mo
    Historic Downtown Simpsonville Office Space

    312 S Main Street, Simpsonville, SC 29681

    Charming office space in historic downtown Simpsonville with ample parking.
    • Prime location in Historic Downtown Simpsonville with excellent visibility.
    • Elegantly finished reception area.
    • Five potential offices, including one suitable for a conference room.
    • Full kitchen and full bathroom.
    • Ample parking with approximately 12‑14 spaces.
    Updated: Feb 6
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    Simpsonville Office Suite for Rent
    $18 SF/Yr
    2,875 SF
    Simpsonville Office Suite for Rent

    419 Main St, Simpsonville, SC

    Office suite with ample parking and convenient highway access.
    • Convenient access to I‑385 & downtown Simpsonville
    • ±2,875 SF office suite with 8 spacious offices
    • ±50 parking spaces
    • Large reception/lobby and kitchenette
    • Zoned BL City of Simpsonville
    Updated: Nov 24, 2025
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    Simpsonville Office Space For Rent
    $14 SF/Yr
    3,150 SF
    Simpsonville Office Space For Rent

    Office space available for lease in Simpsonville, South Carolina.

    1027 South St, Simpsonville, SC

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    334,000 SF Office Building For Lease
    $19 SF/Yr
    334,000 SF Office Building For Lease

    334,000 SF Office Building For Lease

    300 South St, Simpsonville, SC 29681

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    Simpsonville Flex Space For Rent
    Contact for pricing
    24,635 SF
    Simpsonville Flex Space For Rent

    Flex space featuring warehouses, shops, and office space available for lease.

    514 Palmetto Dr, Simpsonville, SC 29681

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    Simpsonville Office Space Available
    $19 SF/Yr
    12,463 SF
    Simpsonville Office Space Available

    Office space available for lease in Simpsonville, SC.

    100 Allawood Ct, Simpsonville, SC

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    Beck Plaza
    $15 SF/Yr
    Beck Plaza

    1,100 SF Retail Building

    1028 NE Main Street, Simpsonville, SC 29681

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    334,000 SF Office Building For Lease
    $19 SF/Yr
    334,000 SF Office Building For Lease

    334,000 SF Office Building For Lease

    300 South St, Simpsonville, SC 29681

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    Beck Plaza
    $15 SF/Yr
    Beck Plaza

    1,100 SF Retail Building

    1028 NE Main Street, Simpsonville, SC 29681

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    Simpsonville Retail Space For Lease
    Contact for pricing
    7,500 SF
    Simpsonville Retail Space For Lease

    Up to 7,500 SF retail space in Simpsonville, SC.

    721 SE Main St, Simpsonville, SC 29681

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    Simpsonville Office Space For Rent
    $32 SF/Yr
    5,904 SF
    Simpsonville Office Space For Rent

    5,904 SF office space available for lease.

    220 Scuffletown Rd, Simpsonville, SC

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    Commercial Building For Rent
    $14 SF/Yr
    5,000 SF
    Commercial Building For Rent

    Commercial building for rent with showroom and office space.

    926 Fairview Rd, Simpsonville, SC 29680

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    0 Bridgeway
    Contact for pricing
    0 Bridgeway

    ±6,197 SF of office space availalble

    0 Bridgeway Simpsonville, SC 29681, Simpsonville, SC 29681

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    0 Bridgeway
    Contact for pricing
    0 Bridgeway

    ±6,197 SF of office space availalble

    0 Bridgeway Simpsonville, SC 29681, Simpsonville, SC 29681

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    Based on your search, we've compiled 28 Potential Opportunities for your consideration. Besides 14 Active listings in Simpsonville, SC, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 6 Properties for Sales.

    Office Spaces for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Creative Office Space Available
    $6 SF/Yr
    Creative Office Space Available

    Creative office space for lease in Mauldin, South Carolina.

    11 Forrester Drive |, Mauldin, SC 29662

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    Creative Office Space Available
    $6 SF/Yr
    5,876 SF
    Creative Office Space Available

    Creative office space for lease in Mauldin, South Carolina.

    11 Forrester Dr, Mauldin, SC 29662

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    Downtown Greenville Class A Office
    Contact for pricing
    Downtown Greenville Class A Office

    Class A office space available in downtown Greenville.

    220 N Main St, Greenville, SC 29601

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    Office Suites Available For Rent
    $25 SF/Yr
    Office Suites Available For Rent

    Office suites of various sizes available for rent.

    301 N Main St, Greenville, SC 29601

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    Similar Spaces for Sale in Simpsonville, SC

    Consider Similar Space for Sale. We found 6 Spaces matching your search parameters.

    Professional Office Space in Simpsonville
    $425,000
    1,844 SF
    Professional Office Space in Simpsonville

    Adaptable 1,844 sq ft office near downtown Simpsonville.

    117 Hillcrest Avenue, Simpsonville, SC 29681

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    Historic Mill Office Space Available
    Contact for pricing
    8,082 SF
    Historic Mill Office Space Available

    Office space in a renovated historic textile mill.

    300 S St, Simpsonville, SC

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    Main Street Commercial Opportunity
    $750,000
    1.42 Acres
    Main Street Commercial Opportunity

    Property with high visibility and development potential on 1.42 acres.

    1306 NE Main St, Simpsonville, SC

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    Highway Frontage Property For Sale
    $550,000
    0.77 Acres
    Highway Frontage Property For Sale

    Versatile property with highway frontage, ideal for retail or office.

    1304 NE Main St, Simpsonville, SC

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    Simpsonville Commercial Building For Sale
    $3,995,000
    24,000 SF
    Simpsonville Commercial Building For Sale

    24,000 SF building in Simpsonville, SC, renovated in 2013.

    313 N Main St, Simpsonville, SC 29681

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    Versatile Commercial Property For Sale
    $725,000
    2,200 SF
    Versatile Commercial Property For Sale

    Adaptable commercial space with high visibility and convenient highway access.

    1306 NE Main St, Simpsonville, SC 29861

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    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Prime Development Opportunity in Greenville
    Contact for pricing
    Prime Development Opportunity in Greenville

    1.27 acre interstate-visible land for ground lease or build-to-suit.

    39 Airpark Ct, Greenville, SC 29607

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    Land Lease Opportunity in Waxhaw
    $8,000/Mo
    Land Lease Opportunity in Waxhaw

    5.341-acre commercial land for lease in a high-growth area.

    5325 Waxhaw Marvin Road, Waxhaw, NC 28173

    View details
    Commercial Land Near Interstate 40
    $499,900 SF/Yr
    1,860 SF
    Commercial Land Near Interstate 40

    3.96 acres with high visibility near Interstate 40.

    310 Goose Creek Road, Dandridge, TN 37725

    View details
    Prime Commercial Land For Lease
    $285,000 SF/Yr
    Prime Commercial Land For Lease

    3 acres of B-3 zoned land with city amenities.

    220 Silver Lake Road, Church Hill, TN 37642

    View details

    Simpsonville, SC Office Spaces Leasing Opportunities Market Analysis

    Explore Office Spaces leasing options in Simpsonville, SC with 14 listings featured on our commercial real estate exchange. The current inventory includes 45,592 square feet of properties with an estimated lease value of $109 SF/Yr.

    Estimated lease rates for Office Spaces in Simpsonville, SC begin at $12 SF/Yr, with an average of $18 SF/Yr and extend to $32 SF/Yr.
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    Most Searched ZIP Codes in Simpsonville, SC

    • 29681
    • 29680

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