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Simpsonville, SC Office Spaces for Lease

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Greenville, SC Mauldin, SC Fountain Inn, SC Piedmont, SC Greer, SC Pelzer, SC Taylors, SC Duncan, SC
7 properties
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Historic Mill Office Units
Updated: Jun 25
Historic Mill Office Units

300 South St, Simpsonville, SC 29681

Contact for pricing
8,082 sqft
±8,082 SF of office space available across the first floor and mezzanine
±7,068 SF first‑floor open‑concept area
±1,014 SF mezzanine with three private offices and a breakroom
First floor includes a front desk, three individual rooms, open area, and two restrooms
Outdoor patio space included
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Second-Generation Medical Office
Updated: May 22
Second-Generation Medical Office

35 Ray E Talley Ct, Simpsonville, SC 29680

Contact for pricing
7,880 sqft
7,880 SF medical and office space
Second‑generation configuration
Situated in Simpsonville’s busy retail corridor
Just off Fairview Road
Convenient access to I‑385
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Newly Renovated Office Space
Newly Renovated Office Space

205 New Harrison Bridge Road, Simpsonville, SC 29680

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1,425 sqft 5.00 AC lot

Newly renovated office space with a fenced laydown yard for outdoor storage.

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Warehouse with Office Space
Warehouse with Office Space

502 Palmetto Dr, Simpsonville, SC 29681

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18,000 sqft 1.50 AC lot

18,000 SF warehouse with suspended gas heat, heavy 3-phase power, docks and drive-ins, plus 3,000 SF office.

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334,000 SF Office Building For Lease
334,000 SF Office Building For Lease

300 South St, Simpsonville, SC 29681

$19 SF/Yr

334,000 SF Office Building For Lease

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Beck Plaza
Beck Plaza

1028 NE Main Street, Simpsonville, SC 29681

$15 SF/Yr

1,100 SF Retail Building

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0 Bridgeway
0 Bridgeway

0 Bridgeway Simpsonville, SC 29681, Simpsonville, SC 29681

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±6,197 SF of office space availalble

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Based on your search, we've compiled 17 Potential Opportunities for your consideration. Besides 7 Active listings in Simpsonville, SC, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 6 Properties for Sales.

Office Spaces for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Downtown Greenville Office Space Available
Downtown Greenville Office Space Available

101 North Main Street, Greenville, SC 29601

$38.50 SF/Yr
11,085 sqft

Office space for rent in downtown Greenville with amenities.

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Creative Office Space Available
Creative Office Space Available

11 Forrester Drive |, Mauldin, SC 29662

$6.95 SF/Yr
86 sqft

Creative office space for lease in Mauldin, South Carolina.

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Downtown Class A Office Building
Downtown Class A Office Building

300 N Main Street, Greenville, SC 29601

$38.50 SF/Yr
5,414 sqft

Class A office building with attached parking garage in downtown.

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Historic Downtown Greenville Office Space
Historic Downtown Greenville Office Space

130 S Main St, Greenville, SC 29601

$28.25 SF/Yr

Historic office building in downtown Greenville with modern amenities.

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Similar Spaces for Sale in Simpsonville, SC

Consider Similar Space for Sale. We found 6 Spaces matching your search parameters.

Historic Creative Workspace
Historic Creative Workspace

300 South St, Simpsonville, SC 29681

$1,750,000
8,082 sqft

Flexible commercial layout with open work areas, private rooms, offices, restrooms, a breakroom, and an outdoor patio.

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Simpsonville Commercial Building For Sale
Simpsonville Commercial Building For Sale

313 N Main Street, Simpsonville, SC 29681

$3,995,000
24,000 sqft

24,000 SF building in Simpsonville, SC, renovated in 2013.

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Medical Office Space with Existing Buildout
Medical Office Space with Existing Buildout

717 NE Main St, Simpsonville, SC 29681

Contact for pricing
3,000 sqft

Existing chiropractic-office configuration supports continued professional use or conversion for legal and accounting services.

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Second-Generation Medical Office
Second-Generation Medical Office

35 Ray E Talley Ct, Simpsonville, SC 29680

Contact for pricing
7,880 sqft

Well-maintained medical and office space in Simpsonville’s retail corridor near I-385 access.

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Office Unit with Laydown Yard
Office Unit with Laydown Yard

205 New Harrison Bridge Rd, Simpsonville, SC 29680

Contact for pricing
1,425 sqft

Office space paired with a dedicated outdoor storage and staging area.

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Versatile Commercial Property For Sale
Versatile Commercial Property For Sale

1306 NE Main St, Simpsonville, SC 29861

Contact for pricing
2,200 sqft

Adaptable commercial space with high visibility and convenient highway access.

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Simpsonville, SC Office Spaces Lease Rates & Market Statistics

Browse 7 Office Spaces for lease in Simpsonville, SC on Realmo, a commercial real estate marketplace serving the Simpsonville area. The current inventory totals 35,387 square feet of properties.

Asking lease rates for Office Spaces in Simpsonville start at $15 SF/Yr, average $17 SF/Yr, and reach $19 SF/Yr at the top of the market. Pricing across the market is relatively uniform, which simplifies like-for-like comparison between listings. At $17 SF/Yr, the local average runs 30% below South Carolina's state average of $24.29 SF/Yr.

Simpsonville accounts for 4% of the 168 office spaces currently available across Greenville County, where nearby markets include Greenville and Greer.

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