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    Bluffton, SC Office Spaces for Lease

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    11 properties
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    Office Suites with Highway Frontage
    Updated: Jun 3
    Office Suites with Highway Frontage

    2 Westbury Park Way, Bluffton, SC 29910

    $32 SF/Yr
    3,870 sqft
    2002‑built office property fronting Hwy 278 (Fording Island Road) with 250'+ highway frontage
    2 suites available: 1,790 SF and 3,870 SF (total 5,660 SF)
    Bluffton side of Hwy 278 with easy access to major thoroughfares
    Ample on‑site parking for employees and visitors
    Existing tenant mix includes medical, professional, institutional, and local tenants
    View details
    New Bluffton Flex and Retail
    Updated: Mar 5
    New Bluffton Flex and Retail

    5 Kitties Landing, Bluffton, SC 29910

    $25 SF/Yr
    8,000 sqft
    Prime location in the heart of Bluffton, SC, offering excellent access to major highways and nearby cities.
    Two new buildings to be constructed, providing modern and customizable spaces.
    Building 1: 8,000 SF flex building suitable for office, retail, or warehouse uses, can be subdivided.
    Building 2: 3,360 SF restaurant/retail building with a grease trap, also suitable for subdivision.
    Located in a high‑traffic area near residential communities and major retailers.
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    Highway 170 Retail/Office/Medical Space
    Highway 170 Retail/Office/Medical Space

    Bluffton, SC 29909

    $36.50 SF/Yr
    3,970 sqft

    Retail, office, or medical space for sale on Highway 170.

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    Office Unit with Delivery Access
    Office Unit with Delivery Access

    49 Pennington Dr, Bluffton, SC 29910

    Contact for pricing
    1,250 sqft

    Unit D includes a reception area, six offices, a restroom, and rear doors for deliveries and shipping.

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    Turn-Key Medical Office Suite
    Turn-Key Medical Office Suite

    14 OAK FOREST RD, Bluffton, SC 29910

    Contact for pricing
    950 sqft

    Turn-key medical office suite with a waiting area, three exam rooms, private restroom, and kitchenette, ready for immediate occupancy.

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    Single-Story Retail Office Medical Building
    Single-Story Retail Office Medical Building

    128 Bluffton Rd, Bluffton, SC 29910

    Contact for pricing
    2,730 sqft

    Pre-leasing is underway for a single-story retail, office, and medical building with a planned Fall 2026 delivery.

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    Single-Story Medical Office Retail
    Single-Story Medical Office Retail

    128 Bluffton Rd, Bluffton, SC 29910

    Contact for pricing
    2,655 sqft

    Pre-leasing single-story retail and office building planned for delivery in Fall 2026.

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    New Flex Space For Lease
    New Flex Space For Lease

    5 Kitties Landing Dr, Bluffton, SC

    Contact for pricing
    3,360 sqft 1.42 AC lot

    New construction flex space suitable for office, retail, or warehouse.

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    Class A Office Medical Building
    Class A Office Medical Building

    5 Buck Island Rd, Bluffton, SC 29910

    Contact for pricing
    17,525 sqft

    Class A office and medical building with floor-to-ceiling windows and an interior elevator at a highway intersection.

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    Class A Office Space
    Class A Office Space

    New Riverside Vlg Wy, Bluffton, SC 29910

    Contact for pricing

    Office space in mixed-use center with retail and residential.

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    Class A Office Space Available
    Class A Office Space Available

    1 Carecore Dr, Bluffton, SC 29910

    Contact for pricing

    LEED Certified office space for lease in Buckwalter Place.

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    Based on your search, we've compiled 34 Potential Opportunities for your consideration. Besides 11 Active listings in Bluffton, SC, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 15 Properties for Sales.

    Office Spaces for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Flex Space with Warehouse
    Flex Space with Warehouse

    61 Schinger Ave, Ridgeland, SC 29936

    Contact for pricing
    1,680 sqft

    Unit 101 pairs administrative offices with a dedicated warehouse area and break room.

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    Office Suite with Storage
    Office Suite with Storage

    386 Spanish Wells Rd, Hilton Head Island, SC 29926

    Contact for pricing
    2,175 sqft

    High-end finished office space includes extra storage and rear-access double doors with ample parking.

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    Mixed Commercial Space Available
    Mixed Commercial Space Available

    46 Old Wild Horse Road, Hilton Head Island, SC 29926

    Contact for pricing
    1,500 sqft

    1,500 sq. ft. space ideal for retail, office, or storage.

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    Ridgeland Office Space Available
    Ridgeland Office Space Available

    122 Riverwalk Blvd, Ridgeland, SC 29936

    Contact for pricing
    2,600 sqft

    Office space for sublease in well-maintained building.

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    Similar Spaces for Sale in Bluffton, SC

    Consider Similar Space for Sale. We found 15 Spaces matching your search parameters.

    Office-Showroom Warehouse Building
    Office-Showroom Warehouse Building

    29 Kitties Landing Road, Bluffton, SC 29910

    $2,475,000
    10,000 sqft 1.00 AC lot

    Metal-frame office, showroom, and warehouse building with four roll-up doors and full HVAC on about one acre.

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    Office-Showroom Warehouse Facility
    Office-Showroom Warehouse Facility

    29 Kitties Landing Drive, Bluffton, SC 29910

    $2,475,000
    10,000 sqft 1.00 AC lot

    Metal-frame building with fully air-conditioned office/showroom and warehouse space, supported by multiple roll-up doors.

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    Highway 278 Frontage Office Building
    Highway 278 Frontage Office Building

    5 Buck Island Rd, Bluffton, SC 29910

    Contact for pricing
    8,800 sqft

    Class A office/medical building on Highway 278 in Bluffton.

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    Bluffton Office/Medical Building For Sale
    Bluffton Office/Medical Building For Sale

    5 Buck Island Rd, Bluffton, SC 29910

    Contact for pricing
    17,525 sqft

    Class A office/medical building fronting Highway 278 in Bluffton.

    View details
    Class A Office Building Space
    Class A Office Building Space

    1 Carecore Drive, Bluffton, SC 29910

    Contact for pricing
    30,065 sqft

    Office space for sale in Buckwalter Place, Bluffton.

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    Class A Office/Warehouse Complex
    Class A Office/Warehouse Complex

    3095 Soperton Dr, Bluffton, SC 29910

    Contact for pricing
    5,562 sqft

    Luxury office and warehouse space built in 2023.

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    Medical Office Suite
    Medical Office Suite

    4 Okatie Center Boulevard South, Okatie, SC 29909

    Contact for pricing
    3,075 sqft

    Medical office suite available in Okatie Center, located just off Hwy 170 near the Hwy 278 interchange.

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    Office/Warehouse Flex Space with Roll-Up Door
    Office/Warehouse Flex Space with Roll-Up Door

    3095 Soperton Drive, Bluffton, SC 29910

    $2,499,000

    Built in 2023, this flex space combines dedicated office buildout with a climate-controlled warehouse and an electronic roll-up door.

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    Ground-Floor Medical Office
    Ground-Floor Medical Office

    4 Okatie Center Boulevard S, Bluffton, SC 29909

    $950,000

    Furnished suite includes eight exam rooms, reception, patient waiting area, kitchenette, storage, and ADA-compliant access.

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    Under-Construction Flex Space
    Under-Construction Flex Space

    8241 Pinellas Drive, Bluffton, SC 29910

    Contact for pricing

    Light Industrial zoning supports medical, office, restaurant, light assembly, and retail uses in Bluffton.

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    Charming Cottage in Old Town
    Charming Cottage in Old Town

    5728 Guilford Place, Bluffton, SC 29910

    Contact for pricing

    Unique commercial space in the heart of Old Town Bluffton.

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    Retail Buildings with Drive-Through
    Retail Buildings with Drive-Through

    280 Old Bridge Drive, Bluffton, SC 29910

    Contact for pricing

    One building offers drive-through availability, while the other provides retail and office space.

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    Flex Space with Roll-Up Door
    Flex Space with Roll-Up Door

    1504 Fording Island Road, Bluffton, SC 29910

    Contact for pricing

    Includes warehouse/storage space alongside office and retail areas.

    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Commercial Land Near Retail
    Commercial Land Near Retail

    Tift Avenue N, Tifton, GA 31794

    $7,500/Mo

    GB-zoned commercial parcel with public water and sewer near established retail, dining, medical, and financial services.

    View details
    General Business Retail Development Site
    General Business Retail Development Site

    Tift Avenue N, Tifton, GA 31794

    $7,500/Mo

    Approximately 0.66-acre commercial land parcel zoned GB General Business in Tifton.

    View details
    Cleared C-3 Commercial Land Parcel
    Cleared C-3 Commercial Land Parcel

    101 HICKORY Lane, Interlachen, FL 32148

    $775,000/Mo

    Cleared commercial land zoned C-3, offered for lease with option to purchase, including parcels fronting Hickory Lane and SR 20.

    View details
    Prime Development Opportunity in Greenville
    Prime Development Opportunity in Greenville

    39 Airpark Ct, Greenville, SC 29607

    Contact for pricing
    1.27 AC lot

    1.27 acre interstate-visible land for ground lease or build-to-suit.

    View details

    Bluffton, SC Office Spaces Market Trends and Statistics

    Explore Office Spaces leasing options in Bluffton, SC with 11 listings featured on our commercial real estate exchange. The current inventory includes 44,310 square feet of properties with an estimated lease value of $93.50 SF/Yr.

    Estimated lease rates for Office Spaces in Bluffton, SC begin at $25 SF/Yr, with an average of $31.17 SF/Yr and extend to $36.50 SF/Yr.
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    Most Searched ZIP Codes in Bluffton, SC

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    • 29909

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