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Cayce, SC Office Spaces for Lease

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West Columbia, SC Columbia, SC Lexington, SC Gaston, SC Irmo, SC
9 properties
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Industrial Flex Space with Dock Access
Updated: Jun 25
Industrial Flex Space with Dock Access

1305 Dunbar Rd, Cayce, SC 29033

$9 SF/Yr
Approximately 12,759 square feet with ±1,527 SF office, ±1,700 SF back office, and ±9,532 SF warehouse
Warehouse features 22‑foot center height and 16‑foot eaves
Two 10’x12’ roll‑up doors with dock‑high and drive‑in access
6‑inch concrete warehouse floor with heavy 3‑phase power
Fully fenced property built in 2001
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Cayce Office/Medical Space Available
Updated: Aug 8, 2025
Cayce Office/Medical Space Available

1105 State St, Cayce, SC

Contact for pricing
5,670 sqft 0.48 AC lot
Large fenced parking lot
Ideal for professional or medical office use
±5,670 SF one‑story building**
ADA accessible
Walking distance to Guignard Park, pharmacy, grocery store and restaurants
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Office Space with River Views
Office Space with River Views

440 Knox Abbott Dr, Cayce, SC

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6,103 sqft 2.33 AC lot

Office space for rent with excellent views and free parking.

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Demised Office Building Suites
Demised Office Building Suites

1202 Indigo Ave, Cayce, SC 29033

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5,128 sqft

Office building is subdivided into multiple suites ranging from 533 to 3,165 sf, with space available to combine.

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Mixed-Use Retail and Office Suites
Mixed-Use Retail and Office Suites

528-532 Knox Abbott Dr, Cayce, SC 29033

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2,520 sqft

Flexible multi-suite space offers options for retail or office use in a redeveloped mixed-use building.

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Mixed-Use Office and Retail Suites
Mixed-Use Office and Retail Suites

528-532 Knox Abbott Dr, Cayce, SC 29033

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2,078 sqft

Redeveloped building offers flexible, multi-suite space suitable for retail or office use, including a restaurant-ready suite.

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Flexible Retail and Office Suites
Flexible Retail and Office Suites

528-532 Knox Abbott Dr, Cayce, SC 29033

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2,118 sqft

Mixed-use redeveloped building offers flexible suites suited for retail or office use, including a restaurant-ready option.

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Multi-Suite Office Space
Multi-Suite Office Space

528-532 Knox Abbott Dr, Cayce, SC 29033

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825 sqft

Flexible, redeveloped multi-suite space totaling 825 SF with easy access to I-77 and I-26.

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Cayce Class A Office Space
Cayce Class A Office Space

1300 12th St, Cayce, SC 29033

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5,555 sqft

Two-story office building with Class A space for rent.

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Based on your search, we've compiled 19 Potential Opportunities for your consideration. Besides 9 Active listings in Cayce, SC, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 6 Properties for Sales.

Office Spaces for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Riverfront Office and Retail Space
Riverfront Office and Retail Space

325 Taylor St, Columbia, SC 29201

$18 SF/Yr
30,000 sqft

Class A office and retail in Canalside development near Downtown.

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Retail/Office Space for Lease
Retail/Office Space for Lease

1102 Meeting Street, West Columbia, SC 29169

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Approximately 1,800 SF retail/office space available for lease at 1102 Meeting Street in West Columbia.

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Recently Renovated Office Suite
Recently Renovated Office Suite

1205 D Ave, West Columbia, SC 29169

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4,000 sqft

Recently renovated office space features new lighting, HVAC, fresh paint, and improved exterior façade work.

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Medical Office Building For Lease
Medical Office Building For Lease

1706 St Julian Pl, Columbia, SC 29204

Contact for pricing
12,395 sqft

12,395 SF medical office building available for lease.

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Similar Spaces for Sale in Cayce, SC

Consider Similar Space for Sale. We found 6 Spaces matching your search parameters.

Flex Space with Warehouse
Flex Space with Warehouse

2240 Frink St, Cayce, SC 29033

$1,200,000
4,863 sqft 0.83 AC lot

Mixed office and warehouse improvements support a range of light industrial business operations.

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Office Building with Central Air
Office Building with Central Air

989 Knox Abbott Drive, Cayce, SC 29033

$2,050,000
20,000 sqft 1.22 AC lot

Office property with C3 zoning, central air, and an Opportunity Zone designation.

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Office Unit With Parking
Office Unit With Parking

1771 Airport Boulevard, Cayce, SC 29033

$250,000
1,000 sqft

Compact office building with commercial zoning, on-site parking, and additional land area.

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Mixed-Use Retail/Office Space
Mixed-Use Retail/Office Space

2021 State Street, Cayce, SC 29033

Contact for pricing
1,450 sqft

M-1-zoned space near the Cayce Riverwalk entrance with on-site parking.

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Office and Warehouse Investment Property
Office and Warehouse Investment Property

2236 Frink St, Cayce, SC

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5,000 sqft 0.85 AC lot

Office and warehouse property for sale with light industrial zoning.

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Office Units
Office Units

1200 12th Street - 1210 Indigo Avenue, Cayce, SC 29033

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Office units are available for purchase at a Cayce commercial property.

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Cayce, SC Office Spaces Lease Rates & Market Statistics

Browse 9 Office Spaces for lease in Cayce, SC on Realmo, a commercial real estate marketplace serving the Cayce area. The current inventory totals 29,997 square feet of properties.

Asking lease rates for Office Spaces in Cayce start at $9 SF/Yr, average $9 SF/Yr, and reach $9 SF/Yr at the top of the market. Pricing across the market is relatively uniform, which simplifies like-for-like comparison between listings. At $9 SF/Yr, the local average runs 62% below South Carolina's state average of $23.64 SF/Yr.

Cayce accounts for 7% of the 123 office spaces currently available across Lexington County, where nearby markets include Columbia and Lexington. By space type, the market includes 7 office units and 3 office buildings.

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