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    Cayce, SC Office Properties & Spaces for Lease

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    Columbia, SC Greenville, SC Charleston, SC
    8 results
    Mixed-Use Property in Cayce, SC
    $825 /Mo
    7,541 SF

    Mixed-Use Property in Cayce, SC

    528-532 Knox Abbott Dr, Cayce, SC 29033

    Mixed-use property suitable for redevelopment, retail, or office use.

    • Excellent redevelopment, retail, or office opportunity with 8,100 sq ft of flexible space.
    • Prime location across the river from downtown Columbia, SC.
    • High visibility and easy access to I‑77 and I‑26.
    • Located in Cayce, a growing and diverse market.
    • Ideal for businesses seeking retail exposure or office space.
    Updated: Apr 15
    View details
    Cayce Office/Medical Space Available
    $20 SF/Yr
    5,670 SF

    Cayce Office/Medical Space Available

    1105 State St, Cayce, SC

    5,670 SF building suitable for office or medical use.

    • Large fenced parking lot
    • Ideal for professional or medical office use
    • ±5,670 SF one‑story building
    • ADA accessible
    • Walking distance to Guignard Park, pharmacy, grocery store and restaurants
    Updated: Aug 8, 2025
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    Cayce Class A Office Space
    $19 SF/Yr
    5,555 SF

    Cayce Class A Office Space

    Two-story office building with Class A space for rent.

    1300 12th St, Cayce, SC 29033
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    Office Space in Cayce Heart
    $19 SF/Yr
    1,520 SF

    Office Space in Cayce Heart

    Efficient office space with ample parking and landscaped grounds.

    1022 State St, Cayce, SC
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    Office Space in Southern First
    $22 SF/Yr
    1,766 SF

    Office Space in Southern First

    Office suites for lease in Cayce's Southern First Building.

    190 Knox Abbott Drive, Cayce, SC
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    Cayce Mixed-Use Redeveloped Building
    Contact for pricing
    2,520 SF

    Cayce Mixed-Use Redeveloped Building

    Flexible retail and office spaces in a prominent Cayce location.

    528-532 Knox Abbott Dr, Cayce, SC
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    Office Space with River Views
    $23 SF/Yr
    6,103 SF

    Office Space with River Views

    Office space for rent with excellent views and free parking.

    440 Knox Abbott Dr, Cayce, SC
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    Redeveloped Mixed-Use Space in Cayce
    Contact for pricing
    8,100 SF

    Redeveloped Mixed-Use Space in Cayce

    Flexible retail or office space in a growing area.

    528-532 Knox Abbott Dr, Cayce, SC 29033
    View details
    Based on your search, we've compiled 19 Potential Opportunities for your consideration. Besides 8 Active listings in Cayce, SC, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 3 Properties for Sales.

    Explore Office properties & Spaces for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Class-A Mixed-Use Development For Rent
    Contact for pricing
    15,000 SF

    Class-A Mixed-Use Development For Rent

    New mixed-use development with commercial and residential spaces available for rent.

    351 Meeting Street, West Columbia, SC 29169
    View details
    Office and Warehouse Space Available
    Contact for pricing
    4,800 SF

    Office and Warehouse Space Available

    4,800 SF office and warehouse space for lease.

    1100 Charleston Hwy, West Columbia, SC
    View details
    Office Suite in Medical Corridor
    $19 SF/Yr
    3,566 SF

    Office Suite in Medical Corridor

    Office suite with private offices near Lexington Medical Center.

    3634 Sunset Blvd, W, Columbia, SC
    View details
    Elgin Office Space For Lease
    Contact for pricing
    146,483 SF

    Elgin Office Space For Lease

    Office space available for lease in Elgin, South Carolina.

    501 Spears Creek Church Rd, Columbia, SC
    View details

    Explore Similar Spaces for Sale in Cayce, SC

    Consider Similar Space for Sale. We found 3 Spaces matching your search parameters.

    75,000 SF Flex Warehouse
    Contact for pricing
    75,000 SF

    75,000 SF Flex Warehouse

    Expandable flex warehouse with freezer, office space, and ample parking.

    102 Vantage Point Drive, Cayce, SC 29172
    View details
    Office Building Near Downtown Columbia
    $685,000
    5,128 SF

    Office Building Near Downtown Columbia

    Office building with multiple suites, ideal for owner occupant.

    1202 Indigo Ave, Cayce, SC
    View details
    Office and Warehouse Investment Property
    $1,150,000
    5,000 SF

    Office and Warehouse Investment Property

    Office and warehouse property for sale with light industrial zoning.

    2236 Frink St, Cayce, SC
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Land Lease Opportunity in Waxhaw
    $8,000 /Mo

    Land Lease Opportunity in Waxhaw

    5.341-acre commercial land for lease in a high-growth area.

    5325 Waxhaw Marvin Road, Waxhaw, NC 28173
    View details
    Toccoa Commercial Lease Opportunity
    $1,500 /Mo
    306 SF

    Toccoa Commercial Lease Opportunity

    Prime commercial location in Toccoa, GA for lease.

    655 S Pond Street, Toccoa, GA 30577
    View details
    Wilmington Corner Lot For Lease
    $9,000 /Mo

    Wilmington Corner Lot For Lease

    Corner lot in Wilmington, NC, zoned for regional business.

    2726 Shipyard Boulevard, Wilmington, NC 28403
    View details
    Commercial Land Near Interstate 40
    $499,900
    1,860 SF

    Commercial Land Near Interstate 40

    3.96 acres with high visibility near Interstate 40.

    310 Goose Creek Road, Dandridge, TN 37725
    View details

    Cayce, SC Office properties & Spaces Leasing Opportunities Market Analysis

    Explore Office properties & Spaces leasing options in Cayce, SC with 8 listings featured on our commercial real estate exchange. The current inventory includes 313,196,400 square feet of properties with an estimated lease value of $39 SF/Yr.

    Estimated lease rates for Office properties & Spaces in Cayce, SC begin at $19 SF/Yr, with an average of $19 SF/Yr and extend to $20 SF/Yr.
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    Most Searched ZIP Codes in Cayce, SC

    • 29033

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