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    Cayce, SC
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    Cayce, SC Office Spaces for Lease

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    West Columbia, SC Columbia, SC Lexington, SC
    7 results
    Main Street
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    Mixed-Use Property in Cayce, SC
    $825/Mo
    7,541 SF
    Mixed-Use Property in Cayce, SC

    528-532 Knox Abbott Dr, Cayce, SC 29033

    Mixed-use property suitable for redevelopment, retail, or office use.
    • Excellent redevelopment, retail, or office opportunity with 8,100 sq ft of flexible space.
    • Prime location across the river from downtown Columbia, SC.
    • High visibility and easy access to I‑77 and I‑26.
    • Located in Cayce, a growing and diverse market.
    • Ideal for businesses seeking retail exposure or office space.
    Updated: Apr 15
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    Cayce Office/Medical Space Available
    $20 SF/Yr
    5,670 SF
    Cayce Office/Medical Space Available

    1105 State St, Cayce, SC

    5,670 SF building suitable for office or medical use.
    • Large fenced parking lot
    • Ideal for professional or medical office use
    • ±5,670 SF one‑story building
    • ADA accessible
    • Walking distance to Guignard Park, pharmacy, grocery store and restaurants
    Updated: Aug 8, 2025
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    Cayce Class A Office Space
    $19 SF/Yr
    5,555 SF
    Cayce Class A Office Space

    Two-story office building with Class A space for rent.

    1300 12th St, Cayce, SC 29033

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    Office Space with River Views
    $23 SF/Yr
    6,103 SF
    Office Space with River Views

    Office space for rent with excellent views and free parking.

    440 Knox Abbott Dr, Cayce, SC

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    Office Space in Cayce Heart
    $19 SF/Yr
    1,520 SF
    Office Space in Cayce Heart

    Efficient office space with ample parking and landscaped grounds.

    1022 State St, Cayce, SC

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    Office Space in Southern First
    $22 SF/Yr
    1,766 SF
    Office Space in Southern First

    Office suites for lease in Cayce's Southern First Building.

    190 Knox Abbott Drive, Cayce, SC

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    Based on your search, we've compiled 18 Potential Opportunities for your consideration. Besides 7 Active listings in Cayce, SC, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 3 Properties for Sales.

    Office Spaces for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Class-A Mixed-Use Development For Rent
    Contact for pricing
    15,000 SF
    Class-A Mixed-Use Development For Rent

    New mixed-use development with commercial and residential spaces available for rent.

    351 Meeting Street, West Columbia, SC 29169

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    Industrial Space Near Scout Motors
    $6,000/Mo
    7,000 SF
    Industrial Space Near Scout Motors

    7,000 SF industrial building with office and warehouse space.

    220 Gateway Corp Blvd, Columbia, SC

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    Elgin Office Space For Lease
    Contact for pricing
    146,483 SF
    Elgin Office Space For Lease

    Office space available for lease in Elgin, South Carolina.

    501 Spears Creek Church Rd, Columbia, SC

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    Medical Office Building For Lease
    Contact for pricing
    12,395 SF
    Medical Office Building For Lease

    12,395 SF medical office building available for lease.

    1706 St Julian Pl, Columbia, SC 29204

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    Similar Spaces for Sale in Cayce, SC

    Consider Similar Space for Sale. We found 3 Spaces matching your search parameters.

    75,000 SF Flex Warehouse
    Contact for pricing
    75,000 SF
    75,000 SF Flex Warehouse

    Expandable flex warehouse with freezer, office space, and ample parking.

    102 Vantage Point Drive, Cayce, SC 29172

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    Office and Warehouse Investment Property
    $1,150,000
    5,000 SF
    Office and Warehouse Investment Property

    Office and warehouse property for sale with light industrial zoning.

    2236 Frink St, Cayce, SC

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    Office Building Near Downtown Columbia
    $685,000
    5,128 SF
    Office Building Near Downtown Columbia

    Office building with multiple suites, ideal for owner occupant.

    1202 Indigo Ave, Cayce, SC

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    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Land Lease Opportunity in Waxhaw
    $8,000/Mo
    Land Lease Opportunity in Waxhaw

    5.341-acre commercial land for lease in a high-growth area.

    5325 Waxhaw Marvin Road, Waxhaw, NC 28173

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    Prime Development Opportunity in Greenville
    Contact for pricing
    Prime Development Opportunity in Greenville

    1.27 acre interstate-visible land for ground lease or build-to-suit.

    39 Airpark Ct, Greenville, SC 29607

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    Commercial Land in Murrells Inlet
    $2,500/Mo
    Commercial Land in Murrells Inlet

    1.49 acres of commercial land for lease.

    Inlet Square Dr., Murrells Inlet, SC 29576

    View details
    Wilmington Corner Lot For Lease
    $9,000/Mo
    Wilmington Corner Lot For Lease

    Corner lot in Wilmington, NC, zoned for regional business.

    2726 Shipyard Boulevard, Wilmington, NC 28403

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    Cayce, SC Office Spaces Leasing Opportunities Market Analysis

    Explore Office Spaces leasing options in Cayce, SC with 7 listings featured on our commercial real estate exchange. The current inventory includes 28,155 square feet of properties with an estimated lease value of $105 SF/Yr.

    Estimated lease rates for Office Spaces in Cayce, SC begin at $1.31 SF/Yr, with an average of $17 SF/Yr and extend to $23 SF/Yr.
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