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South Carolina Office Spaces for Lease

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Greenville, SC Columbia, SC Charleston, SC Spartanburg, SC North Charleston, SC Rock Hill, SC Myrtle Beach, SC Summerville, SC
996 properties
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Fountian Park
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Cayce Office/Medical Space Available
Cayce Office/Medical Space Available

1105 State St, Cayce, SC

$20 SF/Yr
5,670 sqft

5,670 SF building suitable for office or medical use.

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Faber Center
Faber Center

4000 Faber Place Dr, Unit 300, North Charleston, SC 29405

$129-$22,234/Mo
16 spaces available 11-2,045 sqft

Flexible workspace in Faber Center. Book a tour & get info

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Office Space Available For Rent
Office Space Available For Rent

11 Brendan Way, Greenville, SC 29615

$24.75 SF/Yr
1,400 sqft

Office space available for lease in Greenville, SC.

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Main Street
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Full-Floor Medical Office Suite
Full-Floor Medical Office Suite

4969 Centre Pointe Drive # 100, North Charleston, SC 29418

Contact for pricing
10,363 sqft

Full-floor medical office space at Oaks at Centre Pointe with expansion flexibility for growing practices.

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NOMA Tower
NOMA Tower

220 Main St, Unit 500, Greenville, SC 29601

$129-$22,570/Mo
16 spaces available 11-2,002 sqft

Flexible workspace in NOMA Tower. Book a tour & get info

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Greenville Office Space For Rent
Greenville Office Space For Rent

800 E Washington St, Greenville, SC

$29 SF/Yr
1,846 sqft

Office space for rent near downtown Greenville and I-385.

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First-Generation Office and Medical Suites
First-Generation Office and Medical Suites

8471 Dorchester Road, North Charleston, SC 29420

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6,500 sqft

Flexible, suite-divisible two-story space on a busy commercial corridor with landlord-provided shell build-out.

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Columbia Office Space For Rent
Columbia Office Space For Rent

400 Arbor Lake Drive, Columbia, SC 29223

$12.50 SF/Yr
18,463 sqft

Premier office complex with amenities and interstate visibility in Columbia.

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Professional Office Building with Parking
Professional Office Building with Parking

845 Lowcountry Boulevard # A, Mount Pleasant, SC 29464

Contact for pricing
4,238 sqft

Office suites with windows, shared conference space, and free on-site parking in a high-visibility corridor.

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Office Space in Orchard Park
Office Space in Orchard Park

15 Brendan Way, Greenville, SC 29615

$24.50 SF/Yr
14,981 sqft

Office space for rent with ample parking and easy access.

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Industrial Storage Parcel with Warehouse
Industrial Storage Parcel with Warehouse

2026 Meeting Street Rd, Charleston, SC 29405

$17,500/Mo
4,000 sqft

Cleared, fenced outdoor storage parcel with a 4,000 SF warehouse, grade-level doors, and office space.

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Prime Greenville Location with Amenities
Prime Greenville Location with Amenities

75 Beattie Place, Greenville, SC 29601

$39.50 SF/Yr
83,933 sqft

Office and retail spaces with on-site amenities in Greenville.

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Renovated Flex Building with Warehouse
Renovated Flex Building with Warehouse

5513 Rivers Avenue, North Charleston, SC 29406

Contact for pricing
3,048 sqft

Renovated office/showroom with hardwood floors plus rear warehouse access via two roll-up doors.

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Freestanding Retail or Office Building
Freestanding Retail or Office Building

625 Skylark Drive, Charleston, SC 29407

Contact for pricing
3,925 sqft

Freestanding building with strong signage visibility, positioned near major retail corridors for flexible retail or office use.

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Standalone Industrial Flex Building
Standalone Industrial Flex Building

7268 Peppermill Parkway, North Charleston, SC 29418

Contact for pricing
4,000 sqft

Standalone industrial flex building with fenced laydown yard, office space, warehouse area, and drive-in access.

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Freestanding Warehouse Flex Building
Freestanding Warehouse Flex Building

2960 Rivers Avenue, North Charleston, SC 29405

Contact for pricing
5,000 sqft

Freestanding warehouse flex with office, rollup doors, and a laydown yard on a hard-corner for strong visibility.

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Renovated Second-Floor Office Suite
Renovated Second-Floor Office Suite

516 King Street, Charleston, SC 29403

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4,100 sqft

Completely renovated second-floor suite with new HVAC, restored hardwood floors, and abundant natural light for walkable access.

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Flex Space with Rear Lay-Down Yard
Flex Space with Rear Lay-Down Yard

806-A Beckham Lane, Summerville, SC 29483

Contact for pricing
3,400 sqft

Flex building with office buildout, 16’ clear warehouse, and a rear lay-down yard sized to maneuver tractor trailers.

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Corner Flex Retail-Office Showroom
Corner Flex Retail-Office Showroom

6907 Rivers Avenue, Charleston, SC 29406

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9,200 sqft

Two-story corner building with high visibility, ample parking, and strong roadway exposure for retail, office, or showroom uses.

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Move-In Ready Medical Office Suite
Move-In Ready Medical Office Suite

7041 Saint Andrews Road, Columbia, SC 29212

Contact for pricing
2,752 sqft

Purpose-built clinical space with reception, admin office, multiple operatories, and private suite features for healthcare practices.

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Furnished Executive Corner Office
Furnished Executive Corner Office

10 Shem Drive 100-E, Mount Pleasant, SC 29464

$136/Mo

Corner office with multiple windows, furnished workspace, and utilities included in a full-service lease.

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Office Suite in Medical Corridor
Office Suite in Medical Corridor

3634 Sunset Blvd, W, Columbia, SC

$19 SF/Yr
3,566 sqft

Office suite with private offices near Lexington Medical Center.

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