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    Johns Island, SC
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    Johns Island, SC Office Spaces for Lease

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    Hollywood, SC Ravenel, SC Charleston, SC
    14 results
    Functional Space in Sea Island
    $12 SF/Yr
    2,710 SF
    Functional Space in Sea Island

    3609 River Road, Johns Island, SC 29455

    2,710 SF warehouse and office space for lease.
    • Functional space with 2,710 SF including warehouse and office area.
    • Convenient access to Freshfields Village, downtown Charleston, and the airport.
    • Warehouse includes two drive‑in doors.
    • Located in Sea Island Business Park.
    • Less than 9 miles from Kiawah and Seabrook Islands.
    Updated: Mar 25
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    Showroom and Office Space
    $30 SF/Yr
    1,000 SF
    Showroom and Office Space

    3436 Maybank Hwy, Johns Island, SC

    1,000 SF showroom/office space on Maybank Highway for rent.
    • High visibility location on Maybank Highway
    • 1,000 SF showroom and office space
    • Updated and bright in‑line space
    • Prominent exterior monument signage
    • Ample on‑site parking
    Updated: Aug 28, 2025
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    Class A Executive Office Suite
    Contact for pricing
    1,776 SF
    Class A Executive Office Suite

    Well-appointed Class A executive suite within a landscaped office park, offering shared conference and reception amenities.

    3425 Maybank Hwy, Johns Island, SC 29455

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    Eco-Friendly Office Park Suite
    Contact for pricing
    3,264 SF
    Eco-Friendly Office Park Suite

    Office suites available in a four-building park with eco-friendly design and flexible space sizes.

    3417 Maybank Highway, Johns Island, SC 29455

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    Open Layout Office Studio
    Contact for pricing
    2,000 SF
    Open Layout Office Studio

    Flexible open-plan suite formerly used as an indoor fitness studio, well-suited for a range of general office uses.

    1715 Hollydale Ct, Johns Island, SC 29455

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    Renovated Office Space Available
    $17 SF/Yr
    960 SF
    Renovated Office Space Available

    960 SF office space with excellent visibility.

    900 Main Rd, Johns Island, SC

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    Johns Island Office Suite
    $30 SF/Yr
    550 SF
    Johns Island Office Suite

    550 SF office suite in the heart of Johns Island.

    3546 Maybank Hwy, Johns Island, SC

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    Johns Island Office Space Available
    $16 SF/Yr
    5,880 SF
    Johns Island Office Space Available

    Office space available for lease in Johns Island, SC.

    1810 Paulette Dr, Johns Island, SC

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    Move-in Ready Office Space
    $25 SF/Yr
    1,885 SF
    Move-in Ready Office Space

    Move-in ready office space in Live Oak Square.

    1814 Crowne Commons Way, Johns Island, SC

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    Johns Island Retail/Office Space
    Contact for pricing
    Johns Island Retail/Office Space

    Newly renovated retail, office, or restaurant space on Johns Island.

    3575 Maybank Highway # P, Johns Island, SC 29455

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    Johns Island Freestanding Building
    $25 SF/Yr
    5,000 SF
    Johns Island Freestanding Building

    Move-in ready 5,000 SF building on Johns Island.

    3600 J Henry Cut, Johns Island, SC

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    Maybank Highway Retail/Office Opportunity
    $30 SF/Yr
    3,929 SF
    Maybank Highway Retail/Office Opportunity

    New construction opportunity on Maybank Highway in rapidly expanding Johns Island.

    Southwind Station Maybank Hwy, Johns Island, SC

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    Medical/Professional Office Space Available
    $30 SF/Yr
    4,211 SF
    Medical/Professional Office Space Available

    Single-story office space ready for upfits near new developments.

    2947 Maybank Hwy, Johns Island, SC

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    Maybank Highway Commercial Space
    $40 SF/Yr
    58,136 SF
    Maybank Highway Commercial Space

    New construction with space for medical, office, or retail.

    Maybank Hwy, Johns Island, SC 29455

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    Based on your search, we've compiled 26 Potential Opportunities for your consideration. Besides 14 Active listings in Johns Island, SC, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 4 Properties for Sales.

    Office Spaces for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Prime Showroom/Office/Automotive Space Available
    $8,700,000 SF/Yr
    24,000 SF
    Prime Showroom/Office/Automotive Space Available

    Rare opportunity on US Hwy 17 corridor in West Ashley.

    2137 Savannah Highway, Charleston, SC 29414

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    Savannah Highway Retail/Office Building
    $16 SF/Yr
    2,800 SF
    Savannah Highway Retail/Office Building

    Free-standing 2,800 SF retail or office building for lease.

    2413 Savannah Hwy, Charleston, SC

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    Retail and Office Space Available
    Contact for pricing
    1,500 SF
    Retail and Office Space Available

    Retail and office spaces available for rent.

    4410 Savannah Hwy, Ravenel, SC 29470

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    Ravenel Flex Space Available
    $15 SF/Yr
    4,533 SF
    Ravenel Flex Space Available

    Flex space with office, storage, and highway visibility.

    4509 Savannah Hwy, Ravenel, SC 29470

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    Similar Spaces for Sale in Johns Island, SC

    Consider Similar Space for Sale. We found 4 Spaces matching your search parameters.

    Johns Island Commercial Parcel For Sale
    $299,000
    2.20 Acres
    Johns Island Commercial Parcel For Sale

    2.2-acre commercial parcel on rapidly growing River Road corridor.

    3528 River Road, Johns Island, SC 29455

    View details
    Savannah Highway Office Opportunity
    $1,250,000
    Savannah Highway Office Opportunity

    Prime Johns Island location ideal for office or office building.

    3937 Savannah Highway, Johns Island, SC 29455

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    Class A Office Building
    $1,999,000
    5,945 SF
    Class A Office Building

    Furnished office building with marsh views and ample parking.

    1101 Landfall Way, Johns Island, SC

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    Johns Island Office Space Available
    $395,000
    1,148 SF
    Johns Island Office Space Available

    Office space for sale in Johns Island, South Carolina.

    2359 Bohicket Rd, Johns Island, SC

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    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Commercial Land in Murrells Inlet
    $2,500/Mo
    Commercial Land in Murrells Inlet

    1.49 acres of commercial land for lease.

    Inlet Square Dr., Murrells Inlet, SC 29576

    View details
    Land Lease Opportunity in Waxhaw
    $8,000/Mo
    Land Lease Opportunity in Waxhaw

    5.341-acre commercial land for lease in a high-growth area.

    5325 Waxhaw Marvin Road, Waxhaw, NC 28173

    View details
    Wilmington Corner Lot For Lease
    $9,000/Mo
    Wilmington Corner Lot For Lease

    Corner lot in Wilmington, NC, zoned for regional business.

    2726 Shipyard Boulevard, Wilmington, NC 28403

    View details
    Prime Development Opportunity in Greenville
    Contact for pricing
    Prime Development Opportunity in Greenville

    1.27 acre interstate-visible land for ground lease or build-to-suit.

    39 Airpark Ct, Greenville, SC 29607

    View details

    Johns Island, SC Office Spaces Leasing Opportunities Market Analysis

    Explore Office Spaces leasing options in Johns Island, SC with 14 listings featured on our commercial real estate exchange. The current inventory includes 84,261 square feet of properties with an estimated lease value of $256 SF/Yr.

    Estimated lease rates for Office Spaces in Johns Island, SC begin at $12 SF/Yr, with an average of $25 SF/Yr and extend to $40 SF/Yr.
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