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    South Carolina Commercial Real Estate for Lease

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    3,255 properties
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    New Retail Spaces in Development
    New Retail Spaces in Development

    9601 Ocean Highway, Pawleys Island, SC 29585

    $6,082/Mo
    2,500 sqft

    New retail spaces for lease in Pawleys Island, SC.

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    Medical Office End-Unit Suite
    Medical Office End-Unit Suite

    300 New River Parkway, Suite 6, Hardeeville, SC 29927

    $28 SF/Yr
    1,200 sqft

    Medical/professional end-unit includes reception, multiple exam and treatment rooms, lab area, kitchen, restroom, and storage.

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    North Myrtle Beach Office Space
    North Myrtle Beach Office Space

    1401 Highway 17 S, North Myrtle Beach, SC 29582

    $2,500/Mo
    2,376 sqft

    Office space available within existing rental management office.

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    Office Space in Vista District
    Office Space in Vista District

    500 Taylor Street, Columbia, SC 29201

    $23.25 SF/Yr
    6,782 sqft

    Office spaces for lease in Columbia's popular Vista district.

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    Second-Floor Office Suite
    Second-Floor Office Suite

    12019 Ocean Hwy., Pawleys Island, SC 29585

    $3,100/Mo
    1,800 sqft

    Second-floor Class A office space with open layout, kitchenette, two restrooms, and separate entrance along Highway 17.

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    High-Traffic Retail/Office Space Available
    High-Traffic Retail/Office Space Available

    2903 North Kings Highway, Myrtle Beach, SC 29577

    $16 SF/Yr
    10,361 sqft

    Highly visible commercial space on a primary Myrtle Beach corridor.

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    Inline Retail Space at Shopping Center
    Inline Retail Space at Shopping Center

    117 Rivertown Blvd, Conway, SC 29526

    $24 SF/Yr
    2,000 sqft

    Approximately 2,000 SF in-line retail space available at River Town Plaza, adjacent to Walmart and B&B Theaters.

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    Downtown Beaufort Office Space Available
    Downtown Beaufort Office Space Available

    1011 Bay Street, Beaufort, SC 29902

    $950/Mo
    192 sqft

    Inviting office space in the heart of Downtown Beaufort.

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    Retail Space in Calhoun Falls
    Retail Space in Calhoun Falls

    274 E Savannah St, Calhoun Falls, SC 29628

    $10 SF/Yr
    9,014 sqft

    9,014 SF retail space for lease in Calhoun Falls.

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    Renovated Retail Space Available
    Renovated Retail Space Available

    1012 E Shockley Ferry Rd, Anderson, SC 29624

    $1,500/Mo
    1,800 sqft

    Renovated retail building with frontage and open space.

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    Class A Mixed-Use Redevelopment
    Class A Mixed-Use Redevelopment

    400 Augusta Street, Greenville, SC 29601

    $28 SF/Yr
    3,190 sqft

    Located in Greenville’s Historic Westend, easily accessible to major routes.

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    Warehouse-Flex Suite with Drive-In Doors
    Warehouse-Flex Suite with Drive-In Doors

    3609 River Road, Johns Island, SC 29455

    $12 SF/Yr
    4,610 sqft

    Renovated suite includes a warehouse-flex layout with two drive-in doors, restroom and office space.

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    Creative Studio Space in Greenville
    Creative Studio Space in Greenville

    46 Lois Ave, Greenville, SC 29611

    $425/Mo
    5,800 sqft

    Stand-alone creative studio in Greenville's Arts District for rent.

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    Mount Pleasant Retail Space Available
    Mount Pleasant Retail Space Available

    543 Long Point Road, Mount Pleasant, SC 29464

    $24 SF/Yr
    5,250 sqft

    Retail space in prime Mount Pleasant location, available June 1, 2026.

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    Industrial Flex Building with Storage
    Industrial Flex Building with Storage

    2519 Wessinger Rd, Chapin, SC 29036

    $12 SF/Yr
    10,500 sqft

    Flexible industrial space with clear-span warehouse interiors and large paved outdoor storage.

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    Prime Retail/Office Space Available
    Prime Retail/Office Space Available

    6613 N Kings Hwy, Myrtle Beach, SC 29572

    $12 SF/Yr
    11,970 sqft

    Two-story retail/office space in high-traffic Myrtle Beach location.

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    In-Line Restaurant Retail Space
    In-Line Restaurant Retail Space

    2128 Oakheart Rd, Myrtle Beach, SC 29579

    $34 SF/Yr
    1,200 sqft

    1,200 SF in-line space with front order counter seating, prep kitchen with floor drains, and rear office/restroom.

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    Commercial Space with Drive-Up Windows
    Commercial Space with Drive-Up Windows

    5 S Church Street, Manning, SC 29102

    $1,280/Mo
    1,500 sqft

    1500 sq ft commercial space with drive-up windows.

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    Downtown Beaufort Office Space
    Downtown Beaufort Office Space

    1011 Bay Street, Beaufort, SC 29902

    $700/Mo
    112 sqft

    Office space in the heart of downtown Beaufort.

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    Commercial Office Space with Parking
    Commercial Office Space with Parking

    105-2514 River Rd, Piedmont, SC 29673

    $1,650/Mo
    1,200 sqft

    Flexible office space with modern finishes and on-site parking, available now with water and trash included.

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    New Bluffton Flex and Retail
    New Bluffton Flex and Retail

    5 Kitties Landing, Bluffton, SC 29910

    $25 SF/Yr
    8,000 sqft

    New flex and retail buildings in the heart of Bluffton.

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    Fully Serviced Business Solutions at SC, Columbia - Williams Street. Contact us today to book a tour!
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    Class A Medical Office Building
    Class A Medical Office Building

    1200 Innovation Way, Mount Pleasant, SC 29466

    $28 SF/Yr
    14,084 sqft

    Renovated medical/office building with ample parking in Mt. Pleasant.

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    Industrial Complex with Flexible Units
    Industrial Complex with Flexible Units

    4509 Savannah Highway, Ravenel, SC 29470

    $15.50 SF/Yr
    4,533 sqft

    Multi-building industrial complex with modern construction and efficient layouts.

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