South Carolina Office Properties & Spaces for Rent & Lease

$750 / Mo

44,431 SF

New Office Building in Port Royal

1319 Ladys Island Dr, Port Royal, SC 29935

Centrally located office spaces with shared amenities and ample parking.

Centrally located in Port Royal, SC with terrific access.
Brand new office building.
Large parking lot.
Shared conference room.
Individual offices available for lease.

Updated: Mar 3

View details

$2,218 / Mo

2,360 SF

Myrtle Beach Office/Retail Space

720 Main St, Myrtle Beach, SC 29577

Standalone building with high visibility, suitable for office or retail.

Ideal central Myrtle Beach location with high visibility.
Standalone building offering independence and control.
Excellent accessibility from newly realigned Hwy 501.
Suitable for retail or professional office use.
Ample natural light due to large window facing main street.

Updated: Mar 2

View details

$3,600 / Mo

19,602 SF

Lady's Island Versatile Office Space

Well-conditioned office space ideal for medical, wellness, or traditional office.

27 Kemmerlin Ln, Beaufort, SC 29907

View details

$1,660 / Mo

1,459 SF

Office Space in Sumter, SC

1459 sq ft office space for rent in Sumter.

501 S Wise Dr, Sumter, SC 29150

View details

$5,000 / Mo

Renovated Commercial Space in Beaufort

3,200 SF renovated space ideal for retail or office.

1810 Boundary St, Beaufort, SC 29902

View details

$4,750 / Mo

4,110 SF

Versatile Flex Space in Myrtle Beach

Adaptable commercial space for lease in the Arts & Innovation District.

716 8Th Ave N, Myrtle Beach, SC 29577

View details

$525 / Mo

81 SF

Professional Office Suite in Murrells

Executive office suite with shared amenities on Highway 17.

3955 Highway 17 Byp, Murrells Inlet, SC 29576

View details

$2,400 / Mo

1,250 SF

Murrells Inlet Office Space

Multi-tenant office/retail/medical building with easy highway access. Available 4/1/26.

637 Bellamy Ave, Murrells Inlet, SC 29576

View details

$1,665 / Mo

1,250 SF

Murrells Inlet Office Space

Multi-tenant office/retail/medical building with 1,250 SF available 4/1/26.

637 Bellamy Ave, Murrells Inlet, SC 29576

View details

Aiken Commercial Office Building ForRent

$4,758 / Mo

2,595 SF

Aiken Commercial Office Building ForRent

Commercial office building in a convenient and accessible area.

160 Waterloo St SW, Aiken, SC 29801

View details

$475 / Mo

120 SF

Executive Office Space in Surfside

Executive office space available with included utilities and amenities.

1500 Business St, Surfside Beach, SC 29575

View details

$4,000 / Mo

26,136 SF

Office Space Near Clemson

Two-level office building suitable for various businesses, near Clemson.

865 Old Clemson Hwy, Seneca, SC 29678

View details

$1,500 / Mo

26,136 SF

Seneca Office Space For Lease

Two-level office building suitable for various businesses, near Clemson.

865 Old Clemson Hwy, Seneca, SC 29678

View details

$2,500 / Mo

26,136 SF

Office Space in Seneca, SC

Commercial office space available for lease in Seneca, South Carolina.

865 Old Clemson Hwy, Seneca, SC 29678

View details

Surfside Beach Freestanding Office Building

$2,500 / Mo

1,100 SF

Surfside Beach Freestanding Office Building

Freestanding office building for lease in downtown Surfside Beach.

825 1St Ave N, Surfside Beach, SC 29575

View details

$1,600 / Mo

Renovated Office Space For Rent

Newly renovated 650 SF office space with utilities included.

1 Merchants Ln, Ladys Island, SC 29907

View details

$3,000 / Mo

2,200 SF

Office Warehouse in Murrells Inlet

Office warehouse space for lease with great location and visibility.

11772 S Highway 17 Byp, Murrells Inlet, SC 29576

View details

$3,000 / Mo

1,625 SF

New Flex Development in Murrells

New construction flex space with build-to-suit options available.

4960 Highway 17, Murrells Inlet, SC 29576

View details

$1,100 / Mo

840 SF

New Ellenton Office/Mixed-Use Space

Move-in ready office/mixed-use space in the heart of New Ellenton.

413 Main St S, New Ellenton, SC 29809

View details

$1,800 / Mo

1,874 SF

Remodeled Office Building For Rent

Remodeled office building with high traffic count in Dillon, SC.

1013 Highway 301 N, Dillon, SC 29536

View details

$1,300 / Mo

800 SF

Office or Retail Space Available

800 sq ft space suitable for office or retail.

9898 Merry Ln, Murrells Inlet, SC 29576

View details

$1,300 / Mo

1,485 SF

Dillon, SC Commercial Building

Standalone office/retail building for lease near Dillon's government hub.

307 W Harrison St, Dillon, SC 29536

View details

Premier Commercial Space on Lady's Island

$3,800 / Mo

1,307 SF

Premier Commercial Space on Lady's Island

Two-story commercial space with high visibility on Sam's Point Road.

8 Celadon Dr, Beaufort, SC 29907

View details

$750 / Mo

Downtown Beaufort Office Suite

Professional office suite in historic downtown Beaufort, SC.

711 Bladen Street Ln, Beaufort, SC 29902

View details

South Carolina Office Properties & Spaces Leasing Opportunities Market Analysis

Explore Office Properties & Spaces leasing options in South Carolina with 1921 listings featured on our commercial real estate exchange. The current inventory includes 624,370,021,322 square feet of properties with an estimated lease value of $14,304 /Mo.

Estimated lease rates for Office Properties & Spaces in South Carolina begin at $0.64 SF/Yr, with an average of $24 SF/Yr and extend to $276 SF/Yr.

South Carolina Office Properties & Spaces for Lease

New Office Building in Port Royal

Centrally located office spaces with shared amenities and ample parking.

Myrtle Beach Office/Retail Space

Standalone building with high visibility, suitable for office or retail.

Lady's Island Versatile Office Space

Office Space in Sumter, SC

Renovated Commercial Space in Beaufort

Versatile Flex Space in Myrtle Beach

Professional Office Suite in Murrells

Murrells Inlet Office Space

Murrells Inlet Office Space

Aiken Commercial Office Building ForRent

Executive Office Space in Surfside

Office Space Near Clemson

Seneca Office Space For Lease

Office Space in Seneca, SC

Surfside Beach Freestanding Office Building

Renovated Office Space For Rent

Office Warehouse in Murrells Inlet

New Flex Development in Murrells

New Ellenton Office/Mixed-Use Space

Remodeled Office Building For Rent

Office or Retail Space Available

Dillon, SC Commercial Building

Premier Commercial Space on Lady's Island

Downtown Beaufort Office Suite

South Carolina Office Properties & Spaces Leasing Opportunities Market Analysis

Office Properties & Spaces by market

Properties by type

Popular cities

Popular Categories

South Carolina Office Properties & Spaces for Lease

New Office Building in Port Royal

Centrally located office spaces with shared amenities and ample parking.

Myrtle Beach Office/Retail Space

Standalone building with high visibility, suitable for office or retail.

Lady's Island Versatile Office Space

Office Space in Sumter, SC

Renovated Commercial Space in Beaufort

Versatile Flex Space in Myrtle Beach

Professional Office Suite in Murrells

Murrells Inlet Office Space

Murrells Inlet Office Space

Aiken Commercial Office Building ForRent

Executive Office Space in Surfside

Office Space Near Clemson

Seneca Office Space For Lease

Office Space in Seneca, SC

Surfside Beach Freestanding Office Building

Renovated Office Space For Rent

Office Warehouse in Murrells Inlet

New Flex Development in Murrells

New Ellenton Office/Mixed-Use Space

Remodeled Office Building For Rent

Office or Retail Space Available

Dillon, SC Commercial Building

Premier Commercial Space on Lady's Island

Downtown Beaufort Office Suite

South Carolina Office Properties & Spaces Leasing Opportunities Market Analysis

Office Properties & Spaces by market

Properties by type

Popular cities

Popular Categories

Select Neighborhood

Create New Password