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    South Carolina Live-work Space for Lease

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    Columbia, SC Greenville, SC Charleston, SC
    Historic Mill Office Space Available
    $28 SF/Yr
    53,571 SF

    Historic Mill Office Space Available

    1802 Drayton Road, Suite 140B, Spartanburg, SC 29307

    Creative office space in a vibrant mixed-use community.

    • Located in Drayton Mills Marketplace, a successful adaptive‑reuse mixed‑use community.
    • ±3,934 SF office suite with restored historic mill character including exposed brick, high ceilings, and large windows.
    • Walkable access to restaurants, coffee shops, retail, fitness studio, and salons.
    • Connected to Drayton Mills’ trail network for walking, biking, and tenant events.
    • Flexible space suitable for office, creative studio, co‑working, or boutique professional services.
    Updated: Nov 25, 2025
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    Myrtle Beach Mixed-Use Office Space
    $21 SF/Yr
    4,135 SF

    Myrtle Beach Mixed-Use Office Space

    1101 Johnson Ave, Myrtle Beach, SC

    Office space in vibrant Myrtle Beach district with live-work-play lifestyle.

    • Exceptional location in Myrtle Beach's vibrant district, surrounded by retail, dining, and entertainment.
    • Live‑work‑play lifestyle with upscale residential units above, fostering a built‑in community and foot traffic.
    • Attractive amenities including landscaping, walkable streets, open seating, interactive fountains, and a village‑like atmosphere.
    • Dynamic year‑round events, including cultural festivals and family gatherings.
    Updated: Jul 30, 2025
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    Based on your search, we've compiled 18 Potential Opportunities for your consideration. Besides 2 Active listings in South Carolina, we suggest exploring alternatives. Similar 16 Properties for Sales.

    Explore Similar Spaces for Sale in South Carolina

    Consider Similar Space for Sale. We found 16 Spaces matching your search parameters.

    Iconic Mixed-Use Greenwood Property
    $400,000
    4,753 SF

    Iconic Mixed-Use Greenwood Property

    4,700+ sqft mixed-use property in vibrant Uptown Greenwood.

    204 Main Street, Greenwood, SC 29649
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    Redevelopment Opportunity in Beaufort, SC
    $2,495,000
    2.69 Acres

    Redevelopment Opportunity in Beaufort, SC

    Rare mixed-use redevelopment site with high visibility and trail access.

    12 Neil Road, Beaufort, SC 29906
    View details
    Highway 707 Live/Work Opportunity
    $1,800,000
    2,200 SF

    Highway 707 Live/Work Opportunity

    Unique live/work property with income potential on 3.65 acres.

    11091 Highway 707, Murrells Inlet, SC 29576
    View details
    Versatile Commercial Property on Highway 28
    $1,200,000
    1.67 Acres

    Versatile Commercial Property on Highway 28

    Two warehouse buildings totaling 17,500 SF on 1.67 acres.

    2810 Blue Ridge Boulevard, West Union, SC 29696
    View details
    Twin Garden Home with Pool
    $409,000
    2,375 SF

    Twin Garden Home with Pool

    Well-maintained home with pool, flex space, and community amenities.

    108 Dresden Drive, Goose Creek, SC 29445
    View details
    Greenwood Historic Building Fifth Floor
    $50,000
    1,817 SF

    Greenwood Historic Building Fifth Floor

    Fifth floor of historic building suitable for commercial or residential.

    327 Main St, Greenwood, SC 29646
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    Renovated Live-Work Space on Acreage
    $389,900
    2,400 SF

    Renovated Live-Work Space on Acreage

    Remodeled live-work space on 1.5 acres, suitable for various uses.

    1715 Cane Branch Rd., Loris, SC 29569
    View details
    Rock Hill Versatile Zoned Property
    $250,000
    0.04 Acres

    Rock Hill Versatile Zoned Property

    Charming property in desirable location, suitable for residence or office.

    221 S Charlotte Avenue, Rock Hill, SC 29730
    View details
    Restaurant/Convenience Store with Living Area
    $175,000
    1,500 SF

    Restaurant/Convenience Store with Living Area

    Commercial restaurant/convenience store with living area in Cross Anchor, SC.

    701 Union Highway, Cross Anchor, SC 29335
    View details
    Versatile Residential Office Space
    $395,000

    Versatile Residential Office Space

    Spacious property with living and business potential in Anderson.

    510 E Calhoun Street, Anderson, SC 29621
    View details
    Versatile Mixed-Use Commercial Property
    $750,000
    0.48 Acres

    Versatile Mixed-Use Commercial Property

    Over 5,000 sq ft commercial property with residential area.

    4327 Old Mill Road, Anderson, SC 29623
    View details
    New Ranch Home with CG Zoning
    $199,000
    0.16 Acres

    New Ranch Home with CG Zoning

    New 3-bedroom ranch with commercial zoning flexibility.

    109 NW Haddock Road, Orangeburg, SC 29115
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    Renovated Office and Living Space
    $925,000
    4,138 SF

    Renovated Office and Living Space

    Two-story building with flexible floorplan near Downtown Columbia.

    132 Stonemark Ln, Columbia, SC
    View details
    Live-Work Home with Detached Garage
    $297,900
    891 SF

    Live-Work Home with Detached Garage

    Charming home with heated, insulated garage and 3-phase power.

    11 Bainbridge Dr, Greenville, SC 29611
    View details
    Prosperity SC Acreage For Sale
    $75,000
    1.50 Acres

    Prosperity SC Acreage For Sale

    1.5 acre lot zoned for residential or commercial use.

    Brown Street, Prosperity, SC 29127
    View details
    King Street Live/Work Loft
    $675,000
    840 SF

    King Street Live/Work Loft

    Unique live/work loft in the heart of downtown Charleston.

    487 King St, Charleston, SC 29403
    View details

    South Carolina Live-work space Leasing Opportunities Market Analysis

    Explore Live-work space leasing options in South Carolina with 2 listings featured on our commercial real estate exchange. The current inventory includes 180,120,600 square feet of properties with an estimated lease value of $21 SF/Yr.

    Estimated lease rates for Live-work space in South Carolina begin at $21 SF/Yr, with an average of $21 SF/Yr and extend to $21 SF/Yr.
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