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    Berkeley County, SC Medical Office Space for Lease

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    13 properties
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    Single-Story Office Building
    Updated: Jun 2
    Single-Story Office Building

    255 East Bay Street, Charleston, SC 29401

    $35 SF/Yr
    4,730 sqft $13,795/Mo
    4,730 SF single‑story office building in City of Charleston’s GB (General Business) zoning
    Currently leased to Roper Physician Partners; tenant will vacate with notice
    6 parking spaces included with the lease; 19 marked spaces in front, 2 marked spaces on Pinckney St, and 2 unmarked spaces in the rear
    Landlord will consider leasing “as is,” long‑term ground lease, and redevelopment
    Lease rate listed at $35/SF NNN
    View details
    Moncks Corner Medical Office Sublease
    Updated: Mar 6
    Moncks Corner Medical Office Sublease

    422 Drive In Lane, Moncks Corner, SC 29461

    $22 SF/Yr
    7,490 sqft $13,731/Mo
    Free‑standing ±7,490 SF Class A medical office building.
    Ideal for various medical uses (walk‑in clinic, orthodontist, infusion center, dentist, etc.) or another dialysis clinic.
    Sublease until 1/31/2036.
    Located in Moncks Corner's developing retail district near Walmart Supercenter and Tractor Supply Co.
    Ample parking along the sides and rear.
    View details
    Medical Office Space Available
    Medical Office Space Available

    3508 S Live Oak Dr, Moncks Corner, SC

    $32 SF/Yr
    8,000 sqft $21,333/Mo

    8,000 SF medical office space for lease.

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    West Ashley Medical Office Sublease
    West Ashley Medical Office Sublease

    2270 Ashley Crossing Ln, Charleston, SC

    $32 SF/Yr
    3,746 sqft $9,989/Mo

    3,746 SF medical office space available for immediate sublease.

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    Remodeled Office Space Available
    Remodeled Office Space Available

    1483 Tobias Gadson Blvd, Charleston, SC

    $27 SF/Yr
    1,312 sqft $2,952/Mo

    Centrally located office suites near St. Francis Hospital.

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    Renovating Office Park Suites
    Renovating Office Park Suites

    15 Gamecock Avenue Ste B, Charleston, SC 29407

    Contact for pricing
    3,625 sqft

    Two office suites are available within Orange Grove Office Park with ongoing renovations and quick access to I-26.

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    West Ashley Medical Office Space
    West Ashley Medical Office Space

    846 St Andrews Blvd, Charleston, SC

    $34 SF/Yr
    2,500 sqft $7,083/Mo

    2,500 SF medical office space available March 1, 2025.

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    Office/Medical Space on Saint Andrews
    Office/Medical Space on Saint Andrews

    1014 Saint Andrews, Charleston, SC

    $33.75 SF/Yr
    3,698 sqft $10,400/Mo

    Office or medical space available immediately on a major thoroughfare.

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    Two-Story Freestanding Office Building
    Two-Story Freestanding Office Building

    2125 Charlie Hall Boulevard #First Floor, Charleston, SC 29414

    Contact for pricing

    Entire first floor is available in a centrally located, medically oriented freestanding office building with ample parking.

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    Medical Office Space Available
    Medical Office Space Available

    2620 Clements Ferry Rd, Charleston, SC

    $35 SF/Yr
    18,000 sqft $52,500/Mo

    Medical office space for rent in Charleston's growing submarket.

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    West Ashley Office Space Available
    West Ashley Office Space Available

    1064 Gardner Rd, Charleston, SC 29407

    $24 SF/Yr
    3,812 sqft $7,624/Mo

    Office spaces available in central West Ashley from 962-3,812 SF.

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    Medical Office Space Available
    Medical Office Space Available

    2287 Henry Tecklenburg Dr, Charleston, SC 29414

    $24 SF/Yr

    Medical office space for lease near Bon Secours Hospital.

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    Retail and Medical Office Space
    Retail and Medical Office Space

    State Rd S-8-33, Charleston, SC 29492

    Contact for pricing

    Retail and medical office space at Point Hope community.

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    Based on your search, we've compiled 20 Potential Opportunities for your consideration. Besides 13 Active listings in Berkeley County, SC, we suggest exploring alternatives. Similar 3 Properties for Sales.

    Similar Spaces for Sale in Berkeley County, SC

    Consider Similar Space for Sale. We found 3 Spaces matching your search parameters.

    Free-Standing Office Building
    Free-Standing Office Building

    4476 Leeds Place West, Charleston, SC 29405

    $895,000
    5,000 sqft

    A flexible office layout offers private offices, open bullpen space, and exam-ready rooms for medical or legal use.

    View details
    Northbridge Executive Park Investment
    Northbridge Executive Park Investment

    1176-1180 Sam Rittenberg Blvd, Charleston, SC

    $15,968,500
    54,500 sqft 3.25 AC lot

    Two-building office campus near Ashley Landing redevelopment.

    View details
    Moncks Corner Retail/Office Space
    Moncks Corner Retail/Office Space

    111 A & B N Live Oak, Moncks Corner, SC

    Contact for pricing
    3,000 sqft 0.24 AC lot

    3,000 SF space in the heart of Moncks Corner.

    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Prime Development Opportunity in Greenville
    Prime Development Opportunity in Greenville

    39 Airpark Ct, Greenville, SC 29607

    Contact for pricing

    1.27 acre interstate-visible land for ground lease or build-to-suit.

    View details
    Prime Commercial Lot For Rent
    Prime Commercial Lot For Rent

    Tift Avenue N, Tifton, GA 31794

    $7,500/Mo

    0.66 acre commercial lot with high visibility.

    View details
    WINTER PARK Land Lease Opportunity
    WINTER PARK Land Lease Opportunity

    5589 LAKE HOWELL ROAD, Winter Park, FL 32792

    $8,500/Mo
    23,056 sqft $4.42 SF/Yr

    Commercial land lease opportunity in Winter Park, Florida.

    View details
    Corner Lot on Highway 72
    Corner Lot on Highway 72

    30472 Highway 72, Madison, AL 35756

    $5,000/Mo
    1,875 sqft $32 SF/Yr

    1.7 acre corner lot zoned for commercial, medical, residential.

    View details

    Berkeley County, SC Medical Office Space Market Trends and Statistics

    Explore Medical Office Space leasing options in Berkeley County, SC with 13 listings featured on our commercial real estate exchange. The current inventory includes 53,288 square feet of properties with an estimated lease value of $274.75 SF/Yr.

    Estimated lease rates for Medical Office Space in Berkeley County, SC begin at $22 SF/Yr, with an average of $30.53 SF/Yr and extend to $35 SF/Yr.
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