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    South Carolina Medical Office Space for Lease

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    Brand-New Medical Office with Exam Rooms
    Updated: Jun 5
    Brand-New Medical Office with Exam Rooms

    116 Professional Park Dr., Conway, SC 29526

    $10,634/Mo
    3,988 sqft · $32 SF/Yr
    Brand‑new brick medical office space available for lease at Singleton Ridge Professional Business Park
    9 exam rooms plus 3 private offices, reception and lobby areas, and a medical technician workspace
    Includes a laboratory room and a dedicated computer room with dedicated HVAC
    3 bathrooms and a laboratory/medical support layout designed for clinical use
    25 on‑site parking spaces
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    Class A Medical Office Suite Renovated
    Updated: Jun 18
    Class A Medical Office Suite Renovated

    4310 Highway 17 Business, Murrells Inlet, SC 29576

    $8,000/Mo
    3,557 sqft · $26 SF/Yr
    Suite 103 offers 3,557 SF of Class A medical office space in a healthcare facility in Murrells Inlet, SC
    Tenant Improvement Allowance available for medical users to customize the space for clinical and operational needs
    Utilities, trash service, and janitorial service included in the rent
    Recently renovated building with dedicated patient and service elevators and a shared lobby with a complimentary coffee and beverage station
    Cosatron air purification system and Sentry 30 security system, plus an automatic water shut‑off system after business hours
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    Move-In Ready Second-Floor Office Suite
    Move-In Ready Second-Floor Office Suite

    4717 Highway 17 Bypass, Murrells Inlet, SC 29576

    $1,000/Mo
    863 sqft · $13 SF/Yr

    Second-floor suite with reception area, two private offices, private restroom, and kitchenette, in a high-visibility office building.

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    Professional Office Space Available
    Professional Office Space Available

    5187 Horry Dr., Murrells Inlet, SC 29576

    $3,670/Mo
    1,000 sqft · $44 SF/Yr

    Professional office space for lease in Murrells Inlet, SC.

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    Renovated Fully Furnished Office Building
    Renovated Fully Furnished Office Building

    792 John B White Sr Boulevard, Spartanburg, SC 29306

    $2,808/Mo

    Move-in ready office building with updated finishes and full furnishings, positioned for convenient regional access via major interstates.

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    Build-to-Suit Office Suite
    Build-to-Suit Office Suite

    148 Waterloo Street SW, Aiken, SC 29801

    $3,772/Mo
    1,886 sqft · $24 SF/Yr

    Cold-and-dark office space offered with options for tenant-led buildout for general or medical use.

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    Aiken Office/Medical Space Available
    Aiken Office/Medical Space Available

    5000 Woodside Executive Court, Aiken, SC 29803

    $4,810/Mo
    2,540 sqft · $22 SF/Yr

    Office and medical suites available in a professional Aiken complex.

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    Aiken Office Space for Rent
    Aiken Office Space for Rent

    5000 Woodside Executive Court, Aiken, SC 29803

    $4,810/Mo
    2,540 sqft · $22 SF/Yr

    Renovated office space suitable for medical or administrative uses.

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    Two-Story Professional Office Building
    Two-Story Professional Office Building

    8 Celadon Drive, Beaufort, SC 29907

    $3,800/Mo
    2,250 sqft · $20 SF/Yr

    Corner-positioned office building with flexible unit options and a modified gross structure that covers multiple operating expenses.

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    Class A Office Space
    Class A Office Space

    2315 N Main Street, Anderson, SC 29621

    $3,400/Mo

    Professional office suite for rent in Anderson, SC.

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    Turnkey Medical Office Suites
    Turnkey Medical Office Suites

    4100 N. Main Street, Columbia, SC 29203

    $20 SF/Yr
    3,742 sqft · $6,236/Mo

    Turnkey suites with exam rooms and plumbing, recently renovated common areas, designed for efficient medical operations.

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    Standalone Office/Retail Building
    Standalone Office/Retail Building

    22 Sams Point Way, Beaufort, SC 29907

    $6,400/Mo
    3,526 sqft · $21 SF/Yr

    Standalone building with dedicated parking and monument signage, offered for flexible office, medical, or retail use.

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    Office Suites with Highway Frontage
    Office Suites with Highway Frontage

    2 Westbury Park Way, Bluffton, SC 29910

    $30 SF/Yr
    3,870 sqft · $9,675/Mo

    Two office suites are available with extensive Hwy 278 frontage and ample on-site parking for employees and visitors.

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    Medical Office Suite with Reception
    Medical Office Suite with Reception

    30 Memorial Medical Dr, Greenville, SC 29605

    $18 SF/Yr
    2,336 sqft · $3,504/Mo

    New LVP flooring supports a patient-ready layout with reception, private offices, and accessible restrooms.

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    West Ashley Office Space Available
    West Ashley Office Space Available

    1064 Gardner Road, Charleston, SC 29407

    $24 SF/Yr
    2,652 sqft · $5,304/Mo

    Office spaces for lease in central West Ashley location.

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    Single-Story Office Building
    Single-Story Office Building

    255 East Bay Street, Charleston, SC 29401

    $35 SF/Yr
    4,730 sqft · $13,795/Mo

    Centrally located office building with flexible lease terms and included parking to support medical or professional users.

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    Premier Medical Office Space Available
    Premier Medical Office Space Available

    1650 Skylyn Drive, Spartanburg, SC 29307

    $20 SF/Yr
    7,039 sqft · $11,731/Mo

    Class A medical office space in Spartanburg's prime location.

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    Class A Medical Office Building
    Class A Medical Office Building

    1200 Innovation Way, Mount Pleasant, SC 29466

    $28 SF/Yr
    14,084 sqft · $32,862/Mo

    Renovated medical/office building with ample parking in Mt. Pleasant.

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    Two-Story Office Building For Rent
    Two-Story Office Building For Rent

    123 Lawand Dr, Columbia, SC 29210

    $16 SF/Yr
    3,960 sqft · $5,583/Mo

    Two-story office building with flexible layout in central Columbia.

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    West Columbia Office/Medical Suite
    West Columbia Office/Medical Suite

    3618 Sunset Blvd., West Columbia, SC 29169

    $18 SF/Yr
    12,000 sqft · $18,000/Mo

    Office/medical suite for lease near Lexington Medical Hospital.

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    Spacious Office and Medical Suite
    Spacious Office and Medical Suite

    345 Patricia Lane, Fort Mill, SC 29708

    $29 SF/Yr
    8,988 sqft · $22,095/Mo

    8,988 SF professional office/medical suite in Fort Mill, SC.

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    Moncks Corner Medical Office Sublease
    Moncks Corner Medical Office Sublease

    422 Drive In Lane, Moncks Corner, SC 29461

    $22 SF/Yr
    7,490 sqft · $13,731/Mo

    Class A medical office building for sublease in Moncks Corner.

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    Seneca Office Space For Lease
    Seneca Office Space For Lease

    865 Old Clemson Highway, Seneca, SC 29678

    $1,500/Mo

    Two-level office building suitable for various businesses, near Clemson.

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    Rock Hill Medical/Office Suites
    Rock Hill Medical/Office Suites

    420 S Herlong Ave, Rock Hill, SC 29732

    $18 SF/Yr
    2,100 sqft · $3,150/Mo

    Medical/office suites in established Rock Hill medical complex for rent.

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    South Carolina Medical Office Space Market Trends and Statistics

    Explore Medical Office Space leasing options in South Carolina with 145 listings featured on our commercial real estate exchange. The current inventory includes 783,750 square feet of properties with an estimated lease value of $1,778 /Mo.

    Estimated lease rates for Medical Office Space in South Carolina begin at $8 SF/Yr, with an average of $24 SF/Yr and extend to $44 SF/Yr.
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