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    South Carolina Office Spaces for Lease

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    Greenville, SC Columbia, SC Charleston, SC North Charleston, SC Spartanburg, SC Rock Hill, SC Myrtle Beach, SC Summerville, SC
    964 properties
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    Medical Office Suite with Exam Rooms
    Medical Office Suite with Exam Rooms

    2891 Tricom Street Ste B, North Charleston, SC 29406

    Contact for pricing

    Suite includes reception, two exam rooms/offices, an open work area, and two bathrooms on an NNN basis.

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    Penthouse Office Floor For Rent
    Penthouse Office Floor For Rent

    1818 E Main St, Easley, SC 29640

    $15 SF/Yr

    Penthouse office floor in a centrally located professional office complex.

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    Retail or Medical Office Suite
    Retail or Medical Office Suite

    1514 Brentwood Dr, Columbia, SC 29206

    $35 SF/Yr
    5,680 sqft

    New construction suite in a mixed-use building visible from Forest Drive along the Forest Acres retail corridor.

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    Efficient Commercial Building with Storage
    Efficient Commercial Building with Storage

    1324 Richland St, Columbia, SC

    $22.50 SF/Yr
    1,926 sqft

    New, efficient 1,926 SF commercial building with included amenities.

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    Office/Warehouse Unit with Loading
    Office/Warehouse Unit with Loading

    1131 Shine Ave. Unit 7, Myrtle Beach, SC 29577

    Contact for pricing
    10,000 sqft

    Leasing option includes four temperature-controlled offices, two restrooms, and a heated/cooled warehouse with two loading docks.

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    Refreshed Office Building For Lease
    Refreshed Office Building For Lease

    620 W Evans Street, Florence, SC 29501

    $4,500/Mo
    3,000 sqft

    Standalone office building near Downtown Florence with private parking.

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    Charming Office with Exposed Brick
    Charming Office with Exposed Brick

    192 E Bay Street Ste 204, Charleston, SC 29401

    $25 SF/Yr

    Office space with exposed brick and lots of charm.

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    Private Office Suites For Lease
    Private Office Suites For Lease

    1004 Gervais St, Columbia, SC 29201

    $40 SF/Yr

    Private office suites available for lease with utilities included.

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    Refreshed Office Space Available
    Refreshed Office Space Available

    537 Long Point Road, Mt Pleasant, SC 29464

    Contact for pricing

    Modern office spaces with recent upgrades, ready for business.

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    Ribaut Road Commercial Space
    Ribaut Road Commercial Space

    960 Ribaut Road, Beaufort, SC 29902

    $30/Mo

    Commercial space available for rent in Beaufort, South Carolina.

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    Modern Office Park Suites
    Modern Office Park Suites

    1525 Sam Rittenberg Blvd, Charleston, SC 29407

    Contact for pricing

    Move-in-ready, fully renovated 2025 office suites within a multi-tenant business park offering shared on-site parking.

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    Renovated Office Space on Rivers
    Renovated Office Space on Rivers

    5418-5422 Rivers Ave, North Charleston, SC

    Contact for pricing
    2,150 sqft

    Recently renovated office space with new HVAC and ample parking.

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    Office Space For Lease
    Office Space For Lease

    12 Maple Tree Court |, Greenville, SC 29615

    Contact for pricing
    23 sqft

    Office suites available for lease in Greenville, SC.

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    Industrial Warehouse with Office Space
    Industrial Warehouse with Office Space

    885 Paragon Way, Rock Hill, SC 29730

    Contact for pricing
    300,080 sqft

    Tilt-wall concrete warehouse with 32–35' clear height, truck court, multiple dock doors, and conditioned offices.

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    Second-Floor Office Suite
    Second-Floor Office Suite

    840 Meeting St, West Columbia, SC 29169

    Contact for pricing

    Second-floor office suite with a kitchenette, reception area, four offices, and a conference room.

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    Lower-Level Office Suite with Lab Room
    Lower-Level Office Suite with Lab Room

    1405 Grove Road, Greenville, SC 29605

    Contact for pricing

    Lower-level suite with private offices, conference room, and lab/work room for medical or professional operations.

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    Downtown Columbia Office Space Available
    Downtown Columbia Office Space Available

    1338-1368 Main St, Columbia, SC

    $14 SF/Yr
    965 sqft

    Office spaces for lease in downtown Columbia, South Carolina.

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    First-Floor Retail/Office Suites
    First-Floor Retail/Office Suites

    1233 Ben Sawyer #500/600/700, Mount Pleasant, SC 29464

    Contact for pricing

    Move-in ready first-floor suites with parking and prominent visibility along Ben Sawyer Boulevard.

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    Office Building with I-95 Visibility
    Office Building with I-95 Visibility

    2240 North Douglas Street, Florence, SC 29501

    Contact for pricing

    Office building in a professional business park with visibility from I-95 and convenient access to I-20.

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    Office and Retail Space
    Office and Retail Space

    916 W. Poinsett Street, Greer, SC 29650

    Contact for pricing

    Office/retail space just off Wade Hampton Blvd on busy Poinsett Street in Greer.

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    Main Street Commercial Space Available
    Main Street Commercial Space Available

    1901 Main St, Columbia, SC

    Contact for pricing
    6,754 sqft

    Office and retail space with amenities on Main Street.

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    Daniel Island Office Space Available
    Daniel Island Office Space Available

    210 Seven Farms Dr, Charleston, SC

    $29.50 SF/Yr
    9,000 sqft

    Ground floor office space with private offices, conference room, and more.

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    Executive Office Suites
    Executive Office Suites

    Sullivans Island, SC 29482

    Contact for pricing

    Executive office suites offer large conference and meeting rooms, office equipment, and elevator access with on-site parking.

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    Flex Warehouse with Office Buildout
    Flex Warehouse with Office Buildout

    1022 Industrial Ct, Lexington, SC 29072

    Contact for pricing

    Flex space features 18' clear height and a 9' x 9' roll-up door with a layout including three offices and restrooms.

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