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    Erie County, NY Mixed-use Properties for Sale

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    101 results
    Main Street Mixed-Use Investment
    $699,900
    3,641 SF

    Main Street Mixed-Use Investment

    4444 Main Street, Buffalo, NY 14226

    Renovated 5-unit commercial property on Main Street, Buffalo.

    • Prime Main Street location offers unmatched visibility and high traffic exposure.
    • Fully renovated, mixed‑use commercial property with five distinct income‑producing units.
    • Strong cash flow potential for investors or opportunity for owner‑operators.
    • Versatile spaces suitable for a wide range of business types.
    • On‑site parking lot with approximately 9 spaces.
    Updated: Apr 14
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    Turn-Key Restaurant with Warehouse
    $549,900
    10,908 SF

    Turn-Key Restaurant with Warehouse

    898 Genesee Street, Buffalo, NY 14211

    Restaurant, renovated apartment, and warehouse for diverse income streams.

    • Turn‑key, fully operational restaurant with all equipment and furnishings for immediate income generation.
    • Expansive commercial/industrial warehouse with loading door and generous storage.
    • Recently renovated three‑bedroom space adaptable for office, staff quarters, or additional rental unit.
    • Potential for multiple income streams from restaurant, warehouse, and residential space.
    • Warehouse features a new roof.
    Updated: Dec 30, 2025
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    Harlem Road Commercial Opportunity
    $519,999
    6,119 SF

    Harlem Road Commercial Opportunity

    6,119 Sqft building on 0.62-acre lot in high-traffic location.

    1113- 1125 Harlem Road, Buffalo, NY 14227
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    Harlem Road Commercial Opportunity
    $519,999
    6,119 SF

    Harlem Road Commercial Opportunity

    High-traffic location suitable for office, retail, or mixed-use redevelopment.

    1113- 1125 Harlem Road, Buffalo, NY 14227
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    Corner Investment Opportunity in Hamburg
    $549,900
    5,828 SF

    Corner Investment Opportunity in Hamburg

    Fully tenant-occupied commercial property with strong cash flow.

    4572 Clark Street, Hamburg, NY 14075
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    Lancaster Mixed-Use Investment Opportunity
    $669,000
    9,856 SF

    Lancaster Mixed-Use Investment Opportunity

    Mixed-use property in Lancaster Village with retail and residential units.

    5476 Broadway Street, Lancaster, NY 14086
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    Elmwood Village Mixed-Use Opportunity
    $799,000
    4,662 SF

    Elmwood Village Mixed-Use Opportunity

    Mixed-use property in vibrant Elmwood Village with commercial potential.

    615 Elmwood Avenue, Buffalo, NY 14222
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    Main Street Mixed-Use Investment
    $399,000
    4,620 SF

    Main Street Mixed-Use Investment

    High-visibility mixed-use property with income potential on Main Street.

    2290 Main Street, Buffalo, NY 14214
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    Mixed-Use Building in Seneca District
    $449,900
    4,515 SF

    Mixed-Use Building in Seneca District

    Mixed-use property with storefronts and updated apartments in Buffalo.

    2096 Seneca Street, Buffalo, NY 14210
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    Updated Mixed-Use Investment Opportunity
    $449,900
    7,748 SF

    Updated Mixed-Use Investment Opportunity

    Updated mixed-use property near Cazenovia Park with high income potential.

    2342 Seneca Street, Buffalo, NY 14210
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    Elmwood Village Mixed-Use Investment
    $449,000
    4,746 SF

    Elmwood Village Mixed-Use Investment

    Mixed-use property in desirable location with income and appreciation potential.

    1094 Elmwood Avenue, Buffalo, NY 14222
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    Mixed-Use Building on Bailey Avenue
    $425,000
    10,541 SF

    Mixed-Use Building on Bailey Avenue

    10,541 SF mixed-use building with retail and warehouse space.

    2824 Bailey Ave, Buffalo, NY 14215
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    Versatile Mixed-Use Investment Opportunity
    $259,900
    4,002 SF

    Versatile Mixed-Use Investment Opportunity

    Mixed-use property with commercial space and remodeled residential unit.

    543 S Park Avenue, Buffalo, NY 14204
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    Mixed-Use Property in Buffalo, NY
    $149,000
    4,160 SF

    Mixed-Use Property in Buffalo, NY

    Mixed-use property with bar/restaurant and two apartments for sale.

    1263 Clinton Street, Buffalo, NY 14206
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    Mixed-Use Property in Prime Location
    $429,900
    5,408 SF

    Mixed-Use Property in Prime Location

    Versatile property with commercial space and residential apartments.

    41 Elmwood Avenue, Buffalo, NY 14201
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    Mixed-Use Property Near Larkin Square
    $249,000
    3,408 SF

    Mixed-Use Property Near Larkin Square

    Mixed-use property with recent improvements, near Larkin Square.

    995 Exchange Street, Buffalo, NY 14210
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    Seneca Street Mixed-Use Investment Opportunity
    $149,900
    2,806 SF

    Seneca Street Mixed-Use Investment Opportunity

    Rehabbed mixed-use property with storefront and apartment near Cazenovia Park.

    2346 Seneca Street, Buffalo, NY 14210
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    Renovated Mixed-Use Building, Buffalo
    $499,000
    2,626 SF

    Renovated Mixed-Use Building, Buffalo

    Fully renovated mixed-use building in a convenient Buffalo location.

    970 Sycamore Street, Buffalo, NY 14212
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    Mixed-Use Property Near New Development
    $259,900
    4,002 SF

    Mixed-Use Property Near New Development

    Investment opportunity near new apartments, suitable for various businesses.

    543 S Park Avenue, Buffalo, NY 14204
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    Mixed-Use Building in Hertel Business District
    $950,000
    10,320 SF

    Mixed-Use Building in Hertel Business District

    9-unit mixed-use building with storefronts and apartments in prime location.

    1661 Hertel Avenue, Buffalo, NY 14216
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    Mixed-Use Building with Renovation Potential
    $199,000
    6,100 SF

    Mixed-Use Building with Renovation Potential

    Five-unit mixed-use building with renovation and income growth potential.

    696 Genesee Street, Buffalo, NY 14211
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    Genesee Street Mixed-Use Redevelopment Opportunity
    $570,000
    12,720 SF

    Genesee Street Mixed-Use Redevelopment Opportunity

    Mixed-use property in Cheektowaga, NY, ideal for redevelopment.

    2376 Genesee Street, Buffalo, NY 14225
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    Mixed-Use Building in Springville, NY
    $115,000
    4,108 SF

    Mixed-Use Building in Springville, NY

    4,108 SF mixed-use building in Springville's B-1 Business District.

    26 W Main Street, Springville, NY 14141
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    Mixed-Use Building in Springville, NY
    $115,000
    4,108 SF

    Mixed-Use Building in Springville, NY

    Mixed-use building with commercial and residential potential in Springville.

    26 W Main Street, Springville, NY 14141
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    Erie County, NY Mixed-Use Properties Investment Opportunities Market Analysis

    Explore 5000+ mixed-use properties for sale in Erie County, NY, showcased through 101 active listings on our real estate platform. These investment opportunities span a total of 862,003 square feet of properties for sale, with an estimated market value of $62,826,997.

    Sale prices for multi use buildings in Erie County, NY start at $115,000, averaging $766,182, and reaching up to $3,950,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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