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    Erie County, NY Medical Office Space for Lease

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    Medical Office Space with Exam Rooms
    Updated: Jun 11
    Medical Office Space with Exam Rooms

    4085 Seneca Street, Buffalo, NY 14224

    $2,750/Mo
    1,900 sqft 0.47 AC lot
    1,900‑square‑foot medical office property on 0.47 acres
    Four exam rooms, waiting room, and dedicated billing office
    Individual rooms may be available for lease, subject to owner approval
    Ample parking and accessible approach with ramp
    Forced‑air heating with natural gas and central air conditioning
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    New Retail Space Near I-90
    Updated: Sep 5
    New Retail Space Near I-90

    6842 Main Street, Williamsville, NY 14221

    $22 SF/Yr
    2,000 sqft
    2,000 SF retail space available for lease
    Built in 2025
    Suitable for retail, light medical, or small professional office use
    Physical therapy and chiropractic uses specifically identified
    Located at 6842 Main Street, Williamsville, NY 14221
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    Medical Office Space Available
    Medical Office Space Available

    4893 Transit Road, Lancaster, NY 14043

    $25 SF/Yr
    3,004 sqft

    3,004 SF medical suite for lease on Transit Road.

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    Turnkey Medical Office Suite
    Turnkey Medical Office Suite

    9097 Main Street, Clarence, NY 14031

    $18 SF/Yr
    3,700 sqft

    Fully built-out medical and professional space with multiple private offices, reception area, and several exam or treatment rooms.

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    Private-Entrance Office Suite
    Private-Entrance Office Suite

    4085 Seneca Street, West Seneca, NY 14224

    $2,750/Mo
    1,843 sqft

    Flexible office space with private entrance, lobby, air conditioning, and handicap-accessible ramp in a four-office complex.

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    West Seneca Medical/Office Space
    West Seneca Medical/Office Space

    220 Center Road, West Seneca, NY 14224

    $4,000/Mo
    4,500 sqft

    4,500+/- SF medical/office space in high-traffic West Seneca location.

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    Professional Office Space For Rent
    Professional Office Space For Rent

    5811 South Park Avenue, Hamburg, NY 14075

    $8.95 SF/Yr
    11,000 sqft 4.96 AC lot

    Office space ranging from 800 to 11,000 square feet.

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    Versatile Space in Catalyst Fitness Plaza
    Versatile Space in Catalyst Fitness Plaza

    5087 Broadway, Depew, NY 14043

    $12 SF/Yr
    23,000 sqft

    Medical office, retail, and warehouse spaces available for lease.

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    Medical Office Suites
    Medical Office Suites

    1829 Maple Road, Williamsville, NY 14221

    $18 SF/Yr

    Two available suite sizes, on-site parking, and natural light support a range of professional office configurations.

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    Medical Office Suites
    Medical Office Suites

    700 Michigan Ave., Buffalo, NY 14203

    Contact for pricing
    3,500 sqft

    Two adjacent medical office suites total 6,026 SF within a dedicated parking-equipped medical arts center.

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    Medical Office Building with Adjacent Lot
    Medical Office Building with Adjacent Lot

    3083 William St, Buffalo, NY 14227

    Contact for pricing
    7,404 sqft

    Medical-focused building with an adjacent parcel and second-floor office space.

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    Medical Office Space with Flexible Layouts
    Medical Office Space with Flexible Layouts

    400 International Dr, Buffalo, NY 14221

    $19 SF/Yr

    Lease modern medical office space with flexible layouts, modern finishes, and ample parking near major transportation routes.

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    West Seneca Medical Office Suites
    West Seneca Medical Office Suites

    550 Orchard Park Road, West Seneca, NY 14224

    Contact for pricing
    6,495 sqft

    Medical office suites available for lease in West Seneca.

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    Medical Building with Development Potential
    Medical Building with Development Potential

    3083 William Street, Cheektowaga, NY 14227

    Contact for pricing
    3,200 sqft

    Partially leased medical building with developable lot on William Street.

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    Medical Office Suites
    Medical Office Suites

    310 Sterling Dr, Orchard Park, NY 14127

    Contact for pricing
    1,181 sqft

    Medical office suites within Sterling Medical Park with ample on-site parking along the Milestrip retail corridor.

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    Built-Out Medical Office Space
    Built-Out Medical Office Space

    551 Farber Lakes Drive, Williamsville, NY 14221

    Contact for pricing
    3,507 sqft

    Specialized professional space includes medical office and spa-oriented improvements with dedicated building signage.

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    Updated Office Space For Rent
    Updated Office Space For Rent

    5763 Seneca Street, Elma, NY 14059

    $3,500/Mo

    Newly updated office space in Elma, turn-key ready.

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    Medical Office Suite on Second Floor
    Medical Office Suite on Second Floor

    52 South Union Road, Williamsville, NY 14221

    Contact for pricing
    7,162 sqft

    7,162 SF second-floor office suite in a two-story, elevator-equipped medical/professional building with ample parking.

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    Versatile Commercial Space For Lease
    Versatile Commercial Space For Lease

    Derby, NY 14047

    Contact for pricing
    2,000 sqft

    Adaptable commercial space suitable for medical, recreational, or retail businesses.

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    Medical Office Space Available
    Medical Office Space Available

    700 Michigan Ave., Buffalo, NY 14203

    Contact for pricing
    3,500 sqft

    Medical office suites in downtown Buffalo near medical campus.

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    Medical Office Suites
    Medical Office Suites

    550 Orchard Park Rd, Buffalo, NY 14224

    Contact for pricing
    2,550 sqft

    Healthcare-focused office suites are available within Western New York Medical Park, featuring attractive common areas and ample parking.

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    Tonawanda Freestanding Building For Lease
    Tonawanda Freestanding Building For Lease

    935 Sheridan, Tonawanda, NY 14150

    Contact for pricing
    7,920 sqft

    Freestanding building in Tonawanda, ideal for office, medical, or retail.

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    Transit Road Retail/Office Space
    Transit Road Retail/Office Space

    5841 - 5859 Transit Road, East Amherst, NY 14051

    $17.50 SF/Yr

    Retail and office spaces available in high-traffic Transit Valley Plaza.

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    Medical Office Suite with Common Areas
    Medical Office Suite with Common Areas

    550 Orchard Park Rd, West Seneca, NY 14224

    Contact for pricing
    1,200 sqft

    Healthcare office suite with common areas and vending options, plus ample parking.

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    Erie County, NY Medical Office Space Market Trends and Statistics

    Explore Medical Office Space leasing options in Erie County, NY with 48 listings featured on our commercial real estate exchange. The current inventory includes 219,339 square feet of properties with an estimated lease value of $213.27.

    Estimated lease rates for Medical Office Space in Erie County, NY begin at $2.50 SF/Yr, with an average of $15.23 SF/Yr and extend to $25 SF/Yr.
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