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    Erie County, NY Medical Office Space for Lease

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    New York, NY Brooklyn, NY Bronx, NY
    63 results
    Main Street Commercial Space Available
    $2,400/Mo
    4,620 SF

    Main Street Commercial Space Available

    2290 Main Street, Buffalo, NY 14214

    First floor commercial space on Main Street, Buffalo, NY.

    • High visibility location on busy Main Street corridor.
    • Flexible layout suitable for office, medical, or retail use.
    • Welcoming entrance lobby for a positive first impression.
    • Multiple private office rooms.
    • Easy transition with minimal modifications needed.
    Updated: Feb 28
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    Getzville Salon Suite For Lease
    $725/Mo

    Getzville Salon Suite For Lease

    315 Campbell Boulevard, Getzville, NY 14068

    Private salon suite available for lease in Getzville, NY.

    • Built‑out salon suite, adaptable for various professionals.
    • Access to Vibe Studios' amenities: shared waiting room, two bathrooms, shared washer/dryer.
    • Utilities included in rent (Wi‑Fi, heat, electric).
    • Ample parking available.
    • Property built in 2021.
    Updated: Mar 25
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    Elmwood Avenue Professional Office Space
    $15 SF/Yr
    7,344 SF

    Elmwood Avenue Professional Office Space

    3,000 SF office space in high-traffic Kenmore/Elmwood corridor.

    2555 Elmwood Avenue, Buffalo, NY 14217
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    Commercial Office Building Near Route
    $249,900 SF/Yr
    1,500 SF

    Commercial Office Building Near Route

    Well-maintained office building suitable for various professional uses.

    8975 Boston State Road, Colden, NY 14033
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    Medical Building with Development Potential
    $650,000 SF/Yr
    3,200 SF

    Medical Building with Development Potential

    Partially leased medical building with developable lot on William Street.

    3083 William St, Cheektowaga, NY 14227
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    Medical Office Space For Rent
    $10 SF/Yr
    11,512 SF

    Medical Office Space For Rent

    Medical office space available for lease in Clarence, New York.

    8705 Sheridan Drive, Williamsville, NY 14221
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    Clarence Hollow Retail/Office Space
    $15 SF/Yr
    12,036 SF

    Clarence Hollow Retail/Office Space

    Retail, medical, or office space in Clarence Hollow.

    10995 Main St, Clarence, NY 14031
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    Medical/Professional Office Space Available
    $18 SF/Yr
    10,888 SF

    Medical/Professional Office Space Available

    Medical/professional office space for rent in Williamsville, NY.

    1829 Maple Road, Williamsville, NY 14221
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    Kenmore Avenue Retail/Office/Medical Space
    $8 SF/Yr
    12,270 SF

    Kenmore Avenue Retail/Office/Medical Space

    5,600 SF space for lease, suitable for retail/office/medical.

    974-976 Kenmore Ave, Buffalo, NY 14216
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    Remodeled Office Building in East Amherst
    $4,500/Mo
    3,112 SF

    Remodeled Office Building in East Amherst

    Premium remodeled office space in a vibrant business park.

    6483 Transit Rd, East Amherst, NY
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    Premier Medical Office Suites Available
    $18 SF/Yr
    16,194 SF

    Premier Medical Office Suites Available

    Two Class-A office suites in Lakeshore Medical Park, Hamburg, NY.

    4901 Camp Rd, Hamburg, NY 14075
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    Medical Office Space Available 2025
    $16 SF/Yr
    20,437 SF

    Medical Office Space Available 2025

    Medical office space available for lease in 2025.

    2733 Wehrle Drive, Williamsville, NY 14221
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    Springville Medical/Office Space Available
    $14 SF/Yr
    18,589 SF

    Springville Medical/Office Space Available

    Medical/office space for lease in Springville, New York.

    27 Franklin St, Springville, NY 14141
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    Niagara Ontario Plaza Leasing Opportunity
    $10 SF/Yr
    43,787 SF

    Niagara Ontario Plaza Leasing Opportunity

    Revitalized commercial hub with high traffic and unmatched accessibility.

    2211 Niagara Street, Buffalo, NY 14207
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    Versatile Space in Catalyst Fitness Plaza
    Contact for pricing
    23,000 SF

    Versatile Space in Catalyst Fitness Plaza

    Medical office, retail, and warehouse spaces available for lease.

    5087 Broadway, Depew, NY 14043
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    Remodeled Office Space on Transit
    Contact for pricing
    3,112 SF

    Remodeled Office Space on Transit

    Remodeled office space in a vibrant East Amherst business park.

    6483 Transit Rd, East Amherst, NY 14051
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    Orchard Park Retail Opportunity
    Contact for pricing
    1,986 SF

    Orchard Park Retail Opportunity

    Retail space for lease in a high-traffic Orchard Park location.

    3310 Southwestern Blvd, Orchard Park, NY 14127
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    West Seneca Medical/Office Space
    Contact for pricing
    4,500 SF

    West Seneca Medical/Office Space

    4,500+/- SF medical/office space in high-traffic West Seneca location.

    220 Center Road, West Seneca, NY 14224
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    Professional Office Space For Rent
    Contact for pricing
    11,000 SF

    Professional Office Space For Rent

    Office space ranging from 800 to 11,000 square feet.

    5811 South Park Avenue, Hamburg, NY 14075
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    Class A Medical Office Space
    $13 SF/Yr
    48,895 SF

    Class A Medical Office Space

    Premier medical office space in a thriving, convenient location.

    3950 East Robinson Road, Amherst, NY 14228
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    Transit Road Retail/Office Space
    $4 SF/Yr

    Transit Road Retail/Office Space

    Retail and office spaces available in high-traffic Transit Valley Plaza.

    5841 - 5859 Transit Road, East Amherst, NY 14051
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    Medical Office Space For Rent
    $16 SF/Yr

    Medical Office Space For Rent

    Medical office space with easy access to major highways.

    2733 Wehrle Drive, Williamsville, NY 14221
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    Prime Medical Office Space Available
    Contact for pricing
    18,210 SF

    Prime Medical Office Space Available

    Medical office space near Kenmore Mercy Hospital, ample plumbing.

    1491 Sheridan Dr, Buffalo, NY 14217
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    Transit Road Build-to-Suit Opportunity
    Contact for pricing
    16,000 SF

    Transit Road Build-to-Suit Opportunity

    Prime commercial land available for ground lease or build-to-suit.

    9450 Transit Road, East Amherst, NY 14051
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    Erie County, NY Medical Office Space Leasing Opportunities Market Analysis

    Explore Medical Office Space leasing options in Erie County, NY with 63 listings featured on our commercial real estate exchange. The current inventory includes 268,653 square feet of properties with an estimated lease value of $900,283.

    Estimated lease rates for Medical Office Space in Erie County, NY begin at $6 SF/Yr, with an average of $36,011 and extend to $650,000.
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