Medical Premises

Erie County, NY Medical Office Space for Sale

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Brooklyn, NY New York, NY Bronx, NY
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Two-Story Medical Office Building
Updated: Sep 25, 2025
Two-Story Medical Office Building

825 Wehrle Drive, Williamsville, NY

$1,845,000
11,822 sqft
Class A medical space featuring multiple exam rooms, offices, reception/waiting area, conference rooms, and business center.
Ample on‑site parking with room to expand.
Superb Thruway and Expressway access.
Easily accessible with multiple points of ingress/egress.
Strong demographics and traffic counts.
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825 Wehrle Drive, Williamsville, NY,

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Versatile Commercial Building in Buffalo
Updated: May 21
Versatile Commercial Building in Buffalo

1609 Genesee Street, Buffalo, NY 14211

$499,900
5,012 sqft · 0.43 AC lot
High‑visibility location on Genesee St with 5,012 sq. ft. of versatile commercial space suitable for various businesses.
Full accessibility features including an ELEVATOR, wheelchair ramp, and wide hallways.
Large 18,731 sq. ft. lot with an OVERSIZED PARKING LOT offering 25+ spaces.
Dual‑level income opportunity with estimated $6,000 total monthly rent.
Building is already configured for professional, clinical, administrative, or community operations.
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Live-Work Building with Chiropractic Office
Live-Work Building with Chiropractic Office

11881 Broadway Street, Alden, NY 14004

$324,900
2,444 sqft · 0.60 AC lot

Mixed-use live-work property with residential living space and a lobby plus two private office rooms.

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Adjoining Medical Office Suites
Adjoining Medical Office Suites

8600 Sheridan Drive, Clarence, NY 14221

$1,500,000
5,792 sqft · 1.10 AC lot

Three bright adjoining office suites offer separate entrances and private bathrooms with ample on-site parking.

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Dental Office with Apartment Upstairs
Dental Office with Apartment Upstairs

484 Ontario Street, Buffalo, NY 14207

$194,900
4,785 sqft · 0.08 AC lot

Investment opportunity: dental office with a spacious 3-bedroom apartment.

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Remodeled Office Building in East Amherst
Remodeled Office Building in East Amherst

6483 Transit Rd, East Amherst, NY 14051

$699,999
3,112 sqft · 0.35 AC lot

Remodeled 3,112 SF office building in a medical park.

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Tonawanda Commercial Building on Sheridan
Tonawanda Commercial Building on Sheridan

2084 Sheridan Dr, Tonawanda, NY 14223

$599,900
4,500 sqft · 0.38 AC lot

Versatile commercial building in a high-traffic location, ideal for investors.

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Historic Church Property with Medical Suite
Historic Church Property with Medical Suite

360 Genesee Street, Buffalo, NY 14204

$999,900
16,438 sqft · 0.87 AC lot

Central church building with sanctuary, medical suite, dining hall, and three on-site apartments with off-street parking.

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Live-Work Building with Separate Office Entrance
Live-Work Building with Separate Office Entrance

3405 North Buffalo Street, Orchard Park, NY 14127

$899,000

Single-story live-work property combines ADA-compatible office space with a 4-bedroom residence and 11 on-site parking spaces.

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Transit Road Retail Opportunity
Transit Road Retail Opportunity

6140 Transit Road, Depew, NY 14043

$1,275,000
2 sqft · 2.76 AC lot

2.76-acre site with existing building in high-traffic area.

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Updated Medical Office Condominium
Updated Medical Office Condominium

37 Maple Road, Buffalo, NY 14221

$299,999
2,100 sqft · 0.18 AC lot

Well-appointed office suite with a large waiting area and conference room, plus ample on-site parking for staff and clients.

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Orchard Park Commercial Property Opportunity
Orchard Park Commercial Property Opportunity

3290 California Road, Orchard Park, NY 14127

$890,000
5,760 sqft · 1.46 AC lot

High-visibility commercial property near Highmark Stadium with redevelopment potential.

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Remodeled Elmwood Village Medical/Office
Remodeled Elmwood Village Medical/Office

142 Bidwell Parkway, Buffalo, NY 14222

$899,999
2,643 sqft

High-end medical/office property in Buffalo's vibrant Elmwood Village.

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Union Road Medical Investment Property
Union Road Medical Investment Property

2100 Union Rd, West Seneca, NY 14224

$1,199,900
6,000 sqft

Cash flowing medical property with long-term tenant on Union Road.

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Medical Office with Dental Buildout
Medical Office with Dental Buildout

476 Hertel Ave, Buffalo, NY 14207

$552,750
3,685 sqft · 0.40 AC lot

Medical office space featuring a dental buildout and parking.

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Spacious Commercial Building in Buffalo
Spacious Commercial Building in Buffalo

1609 Genesee Street, Buffalo, NY 14211

$499,900
5,012 sqft · 0.43 AC lot

Versatile 5,012 sq ft building ideal for various businesses.

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Premium Medical Office Building For Sale
Premium Medical Office Building For Sale

8270 Wehrle Dr, Buffalo, NY 14221

$1,399,000
11,792 sqft · 1.08 AC lot

Medical office building in Williamsville, NY, with modern, flexible layout.

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Single-Story Office Building Near Expressway
Single-Story Office Building Near Expressway

721 Center Road, Buffalo, NY 14224

$380,184
3,600 sqft

3,600 SF office building with two suites and full basement.

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Niagara Falls Blvd Medical/Office Buildings
Niagara Falls Blvd Medical/Office Buildings

2001-2005 Niagara Fls Blvd, Amherst, NY

$1,700,000
18,890 sqft · 0.91 AC lot

Two buildings on Niagara Falls Blvd with high traffic counts.

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Two-Story Office Building For Sale
Two-Story Office Building For Sale

5813 Transit, Depew, NY 14043

$334,900
3,850 sqft

Two-story office building with income potential and on-site parking.

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Transit Road Commercial Property For Sale
Transit Road Commercial Property For Sale

11500 Transit Road, East Amherst, NY 14051

$349,000

Remodeled commercial property on Transit Road, ideal for office/retail.

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Medical Office Buildings on Niagara
Medical Office Buildings on Niagara

2005 Niagara Falls Blvd, Amherst, NY 14228

$1,700,000
19,000 sqft · 0.97 AC lot

Two medical office buildings on a high-traffic boulevard.

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Medical Office Building with Adjacent Lot
Medical Office Building with Adjacent Lot

3083 William Street, Buffalo, NY 14227

$650,000
6,400 sqft

Partially leased medical-focused office building with an adjacent developable parcel for expansion or additional parking.

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Redevelopment Opportunity Former Rite Aid
Redevelopment Opportunity Former Rite Aid

2474 Bailey Ave, Buffalo, NY 14215

$2,500,000
10,209 sqft

Freestanding former Rite Aid in high-traffic Buffalo location.

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Erie County, NY Medical Office Space Market Trends and Statistics

Explore 72 medical office space for sale in Erie County, NY, showcased through 42 active listings on our real estate platform. These investment opportunities span a total of 192,009 square feet of properties for sale, with an estimated market value of $27,535,947.

Sale prices for medical spaces in Erie County, NY start at $194,900, averaging $983,426, and reaching up to $2,500,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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