Medical Premises

Erie County, NY Medical Office Space for Sale

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Mixed-Use Live-Work Property
Updated: May 3
Mixed-Use Live-Work Property

11881 Broadway Street, Alden, NY 14004

$324,900
2,444 sqft 0.60 AC lot
2,444‑square‑foot mixed‑use building on a 0.6‑acre lot
Residential area measures 1,868 square feet
576‑square‑foot commercial section with lobby and two private rooms
Commercial space is currently configured as a chiropractic office
Directly positioned on Broadway in Alden
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11881 Broadway Street, Alden, NY 14004

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Accessible Two-Story Office Building
Updated: May 21
Accessible Two-Story Office Building

1609 Genesee Street, Buffalo, NY 14211

$499,900
5,012 sqft 0.43 AC lot
5,012 SF two‑story brick office building on a 0.43‑acre lot
Valid Certificate of Occupancy with flexible office and multipurpose layouts
Full elevator, wheelchair ramp, and wide hallways for accessible circulation
Four bathrooms, with two on each floor, plus dedicated laundry areas
Oversized parking lot with 25+ spaces and multiple entry points
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Mixed-Use Property with Medical Space
Mixed-Use Property with Medical Space

6575 Transit Road, East Amherst, NY 14051

$999,000
3,330 sqft 1.00 AC lot

The property combines a medical-use commercial area with a renovated residential unit.

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Mixed-Use Property with Dental Office
Mixed-Use Property with Dental Office

484 Ontario Street, Buffalo, NY 14207

$194,900
4,785 sqft 0.08 AC lot

Operating dental office with an upstairs three-bedroom apartment and updated building systems.

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Adjoining Medical Office Suites
Adjoining Medical Office Suites

8600 Sheridan Drive, Clarence, NY 14221

$1,500,000
5,792 sqft 1.10 AC lot

Three bright adjoining office suites offer separate entrances and private bathrooms with ample on-site parking.

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Mixed-Use Property with Dental Office
Mixed-Use Property with Dental Office

484 Ontario Street, Buffalo, NY 14207

$194,900
4,785 sqft 0.08 AC lot

Two-level property combines an operating dental practice with an upstairs residential apartment and updated building systems.

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Mixed-Use Property with Apartments
Mixed-Use Property with Apartments

Buffalo, NY 14226

$799,000
0.34 AC lot

Mixed-use building with commercial space, two apartments, driveway parking, and a garage.

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Remodeled Office Building in East Amherst
Remodeled Office Building in East Amherst

6483 Transit Rd, East Amherst, NY 14051

$699,999
3,112 sqft 0.35 AC lot

Remodeled 3,112 SF office building in a medical park.

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Office Condominium with Conference Room
Office Condominium with Conference Room

37 Maple Road, Buffalo, NY 14221

$299,999
2,100 sqft 0.18 AC lot

Updated office condominium in zoning OB with central air, public sewer, and an extra-large client waiting area.

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Tonawanda Commercial Building on Sheridan
Tonawanda Commercial Building on Sheridan

2084 Sheridan Dr, Tonawanda, NY 14223

$599,900
4,500 sqft 0.38 AC lot

Versatile commercial building in a high-traffic location, ideal for investors.

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Mixed-Use Property with Medical Office
Mixed-Use Property with Medical Office

6575 Transit Road, East Amherst, NY 14051

$999,000
3,330 sqft 1.00 AC lot

Commercially zoned property combines an occupied medical-use suite with a renovated upper-level residence and expansion area.

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Two-Level Medical Office Building
Two-Level Medical Office Building

4080 Delaware Ave, Tonawanda, NY 14150

$850,000
10,322 sqft 1.14 AC lot

Two-level medical/professional building with 50+ parking spaces on a paved, striped lot.

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Spacious Commercial Building in Buffalo
Spacious Commercial Building in Buffalo

1609 Genesee Street, Buffalo, NY 14211

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5,012 sqft 0.43 AC lot

Versatile 5,012 sq ft building ideal for various businesses.

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Mixed-Use Office and Residential Duplex
Mixed-Use Office and Residential Duplex

2533 Sheridan Dr, Buffalo, NY 14150

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4,380 sqft

High-visibility property with first-floor medical or professional office space and second-floor office or two residential units.

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Medical Office Building with Adjacent Lot
Medical Office Building with Adjacent Lot

3083 William Street, Buffalo, NY 14227

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6,400 sqft

Partially leased medical-focused office building with an adjacent developable parcel for expansion or additional parking.

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Medical Office/Retail Building
Medical Office/Retail Building

6140 Transit Rd, Depew, NY 14043

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5,520 sqft

Medical office/retail building in C-2 Shopping Center District on a high-traffic corridor near a new O’Reilly Auto Parts.

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Victorian Office Building with Sauna
Victorian Office Building with Sauna

305 Main Street, Aurora, NY 14052

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4,212 sqft

Professional office with reception, multiple offices, sauna, full basement, and two-car garage.

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Medical/Professional Office Plaza
Medical/Professional Office Plaza

6199 Transit Rd, Depew, NY 14043

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16,763 sqft 1.00 AC lot

Retail and office plaza offering 161 feet of frontage along Transit Road with prominent parking and pylon signage.

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Professional Office Building with Gas Fireplace
Professional Office Building with Gas Fireplace

305 Main St, East Aurora, NY 14052

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4,212 sqft

Highly visible Main Street office building with a professional reception, waiting room, and gas fireplace.

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Medical Office with Dental Buildout
Medical Office with Dental Buildout

476 Hertel Ave, Buffalo, NY 14207

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3,685 sqft 0.40 AC lot

Medical office space featuring a dental buildout and parking.

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Live-Work Building with Separate Office Entrance
Live-Work Building with Separate Office Entrance

3405 North Buffalo Street, Orchard Park, NY 14127

$789,900

Single-story live-work property combines ADA-compatible office space with a 4-bedroom residence and 11 on-site parking spaces.

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Historic Mixed-Use Church Property
Historic Mixed-Use Church Property

360 Genesee St, Buffalo, NY 14204

$880,000
16,438 sqft

Historic church with a medical suite, dining hall, kitchen, and three on-site apartments, plus off-street parking.

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Stabilized Medical Office NNN Building
Stabilized Medical Office NNN Building

2556 Delaware Ave, Buffalo, NY 14216

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4,921 sqft

Fully leased corner medical office building is stabilized on NNN terms with a tenant extending through 2031.

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Renovated Office Space Near Campus
Renovated Office Space Near Campus

11 Summer St, Buffalo, NY

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2,740 sqft 0.57 AC lot

Renovated office space suitable for medical or standard offices.

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Erie County, NY Medical Office Space Market Trends and Statistics

Explore 72 medical office space for sale in Erie County, NY, showcased through 35 active listings on our real estate platform. These investment opportunities span a total of 199,579 square feet of properties for sale, with an estimated market value of $11,140,975.

Sale prices for medical spaces in Erie County, NY start at $194,900, averaging $655,351, and reaching up to $1,500,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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