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    Depew, NY
    Medical Premises

    Depew, NY Medical Office Space for Sale

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    Buffalo, NY Bowmansville, NY Lacombe, LA
    Transit Road Retail Opportunity
    Updated: Mar 25
    Transit Road Retail Opportunity

    6140 Transit Road, Depew, NY 14043

    $1,275,000
    2 sqft
    High‑traffic location on Transit Road with 22,646 AADT
    2.76‑acre site in a C‑2 Shopping Center District
    Adjacent to a new O’Reilly Auto Parts location
    5,520 sq. ft. office/retail building currently on the property
    Located among local and national retailers
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    Two-Story Office Building For Sale
    Updated: Nov 21, 2025
    Two-Story Office Building For Sale

    5813 Transit, Depew, NY 14043

    $334,900
    3,850 sqft
    Great visibility due to corner location just north of Walden Avenue.
    Income potential from existing tenant and ability to subdivide remaining space.
    Suitable for professional office/medical use.
    Fully alarmed building with individual passcard entry for each unit.
    On‑site parking for 15 cars.
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    Union Road Medical/Professional Office
    Union Road Medical/Professional Office

    2355 Union Rd, Cheektowaga, NY

    Contact for pricing
    13,608 sqft · 0.60 AC lot

    Medical/professional office building for sale or lease on Union Road.

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    Turn Any Listing Into an Investment Snapshot Owner equity, real caprate, demand score for every listing. Go To Analytics Center
    Based on your search, we've compiled 12 Potential Opportunities for your consideration. Besides 3 Active listings in Depew, NY, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 1 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Union Road Medical Investment Property
    Union Road Medical Investment Property

    2100 Union Rd, West Seneca, NY 14224

    $1,199,900
    6,000 sqft

    Cash flowing medical property with long-term tenant on Union Road.

    View details
    Medical Office Building with Adjacent Lot
    Medical Office Building with Adjacent Lot

    3083 William Street, Buffalo, NY 14227

    $650,000
    6,400 sqft

    Partially leased medical-focused office building with an adjacent developable parcel for expansion or additional parking.

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    West Seneca Former Medical Office
    West Seneca Former Medical Office

    Buffalo, NY 14224

    Contact for pricing

    36,346 SF medical office space for sale/lease.

    View details
    Two-Story Medical Office Building
    Two-Story Medical Office Building

    825 Wehrle Dr, Williamsville, NY 14221

    $1,845,000
    11,822 sqft

    Two-story medical office building for sale in Amherst, NY.

    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Commercial Lot on Route 332
    Commercial Lot on Route 332

    1386 Hathaway Drive, Farmington, NY 14425

    $125,000
    0.83 AC lot

    Commercial lot suitable for office, medical, retail, or service uses.

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    Commercial Development Parcel with Utilities
    Commercial Development Parcel with Utilities

    Dorsett Heights, Mansfield, PA 16933

    $695,000
    2.76 AC lot

    Commercial-zoned parcel near Route 15 with public water, sewer, cable, and fiber for flexible site planning.

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    Commercial Zoned Land Parcel
    Commercial Zoned Land Parcel

    University Dr., Mansfield, PA 16933

    $495,000
    2.05 AC lot

    2.05-acre commercially zoned parcel with public water, sewer, and telecom utilities for flexible development uses.

    View details
    Commercial Land Near Oswego Hospital
    Commercial Land Near Oswego Hospital

    75-83 W Utica St, Oswego, NY 13126

    $299,000
    0.28 AC lot

    Development opportunity near Oswego Hospital with high visibility and traffic.

    View details

    Off-Market Properties in Depew, NY

    Consider similar Off-Market properties in Depew, NY. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    5102 Transit Rd
    MEDICAL CLINIC

    5102 Transit Rd, Depew, NY 14043-4465

    Value Estimation by Request
    3,501 sqft · 0.89 AC lot
    View details

    Depew, NY Medical Office Space Market Trends and Statistics

    Explore 4 medical office space for sale in Depew, NY, showcased through 3 active listings on our real estate platform. These investment opportunities span a total of 3,852 square feet of properties for sale, with an estimated market value of $1,609,900.

    Sale prices for medical spaces in Depew, NY start at $334,900, averaging $804,950, and reaching up to $1,275,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Top Commercial Asset Segments

    Commercial property segments ranked by active listings on the market

    Office Units 16
    Office buildings 10
    Medical Office Space 6

    Demographics Overview

    Population 25K
    Population Growth (5Y) +1.6%
    Median Household Income $73,373
    College Educated 40.0%

    High-Yield Neighborhoods for Investment

    Identify Depew submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

    Neighborhood Average Price
    14043 $805K

    Taxes & Financing

    Tax Rate vs County Average 2.54 pp above county avg
    Average Loan-to-Value 65.0%

    Listings Trend

    New vs delisted commercial listings in Erie County

    New Delisted

    Total CRE Inventory on Market (SF)

    Average Property Price per SF

    For-sale pricing trends across core commercial property types in Erie County

    Residential Income

    Property Size Breakdown

    The majority of commercial real estate listings in Depew fall within the 100,000+ square foot range.

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