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    South Carolina Commercial Real Estate for Lease

    3,364 results
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    Aiken Commercial Office Building ForRent
    $4,758 / Mo
    2,595 SF

    Aiken Commercial Office Building ForRent

    160 Waterloo St SW, Aiken, SC 29801

    Commercial office building in a convenient and accessible area.

    • Central location in Aiken with easy access to major roadways and downtown amenities.
    • Ample on‑site parking for employees and visitors.
    • Functional layout with private offices, open work areas, and flexible space.
    • Excellent visibility for businesses.
    • Accessible approach with ramp.
    Updated: Mar 6
    View details
    Office Space in Hampton, SC
    Pending
    $800 / Mo
    871 SF

    Office Space in Hampton, SC

    12 Mulberry St E, Hampton, SC 29924

    Two offices with an open area available for rent.

    • Flexible workspace with two offices and an open area behind a partition.
    • Enjoy year‑round comfort with central heating and air conditioning.
    • Durable brick construction.
    • Features electric heating and cooling systems.
    • Public water source.
    Updated: Mar 6
    View details
    North Augusta Restaurant Space Available
    $3,500 / Mo
    1,440 SF

    North Augusta Restaurant Space Available

    Former restaurant for lease in high-demand North Augusta area.

    220 Georgia Ave, North Augusta, SC 29841
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    Restaurant Space in North Augusta
    $3,500 / Mo
    1,440 SF

    Restaurant Space in North Augusta

    Restaurant space near downtown North Augusta, ready for equipment.

    220 Georgia Ave, North Augusta, SC 29841
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    Retail Space on Highway 17
    $8,625 / Mo
    4,500 SF

    Retail Space on Highway 17

    Established retail space with highway frontage in Myrtle Beach.

    10589 N Kings Hwy, Myrtle Beach, SC 29572
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    New Office Building in Port Royal
    $750 / Mo
    44,431 SF

    New Office Building in Port Royal

    Centrally located office spaces with shared amenities and ample parking.

    1319 Ladys Island Dr, Port Royal, SC 29935
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    Myrtle Beach Office/Retail Space
    $2,218 / Mo
    2,360 SF

    Myrtle Beach Office/Retail Space

    Standalone building with high visibility, suitable for office or retail.

    720 Main St, Myrtle Beach, SC 29577
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    Lady's Island Versatile Office Space
    $3,600 / Mo
    19,602 SF

    Lady's Island Versatile Office Space

    Well-conditioned office space ideal for medical, wellness, or traditional office.

    27 Kemmerlin Ln, Beaufort, SC 29907
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    Office Space in Sumter, SC
    $1,660 / Mo
    1,459 SF

    Office Space in Sumter, SC

    1459 sq ft office space for rent in Sumter.

    501 S Wise Dr, Sumter, SC 29150
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    Renovated Commercial Space in Beaufort
    $5,000 / Mo

    Renovated Commercial Space in Beaufort

    3,200 SF renovated space ideal for retail or office.

    1810 Boundary St, Beaufort, SC 29902
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    Versatile Flex Space in Myrtle Beach
    $4,750 / Mo
    4,110 SF

    Versatile Flex Space in Myrtle Beach

    Adaptable commercial space for lease in the Arts & Innovation District.

    716 8Th Ave N, Myrtle Beach, SC 29577
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    Professional Office Suite in Murrells
    $525 / Mo
    81 SF

    Professional Office Suite in Murrells

    Executive office suite with shared amenities on Highway 17.

    3955 Highway 17 Byp, Murrells Inlet, SC 29576
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    Aiken Office Space for Rent
    $4,810 / Mo
    2,540 SF

    Aiken Office Space for Rent

    Renovated office space suitable for medical or administrative uses.

    5000 Woodside Executive Ct, Aiken, SC 29803
    View details
    Downtown Aiken Office Space Available
    Pending
    $437 / Mo
    5,258 SF

    Downtown Aiken Office Space Available

    Professional office space for lease in Downtown Aiken, South Carolina.

    231 Barnwell Ave NW, Aiken, SC 29801
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    Murrells Inlet Office Space
    $2,400 / Mo
    1,250 SF

    Murrells Inlet Office Space

    Multi-tenant office/retail/medical building with easy highway access. Available 4/1/26.

    637 Bellamy Ave, Murrells Inlet, SC 29576
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    Murrells Inlet Office Space
    $1,665 / Mo
    1,250 SF

    Murrells Inlet Office Space

    Multi-tenant office/retail/medical building with 1,250 SF available 4/1/26.

    637 Bellamy Ave, Murrells Inlet, SC 29576
    View details
    Executive Office Space in Surfside
    $475 / Mo
    120 SF

    Executive Office Space in Surfside

    Executive office space available with included utilities and amenities.

    1500 Business St, Surfside Beach, SC 29575
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    Aiken Industrial Space For Rent
    $8,000 / Mo
    15,080 SF

    Aiken Industrial Space For Rent

    15,080 SF industrial space on Equestrian Corridor.

    2969 Wagener Rd, Aiken, SC 29801
    View details
    Office Space Near Clemson
    $4,000 / Mo
    26,136 SF

    Office Space Near Clemson

    Two-level office building suitable for various businesses, near Clemson.

    865 Old Clemson Hwy, Seneca, SC 29678
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    Seneca Office Space For Lease
    $1,500 / Mo
    26,136 SF

    Seneca Office Space For Lease

    Two-level office building suitable for various businesses, near Clemson.

    865 Old Clemson Hwy, Seneca, SC 29678
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    Office Space in Seneca, SC
    $2,500 / Mo
    26,136 SF

    Office Space in Seneca, SC

    Commercial office space available for lease in Seneca, South Carolina.

    865 Old Clemson Hwy, Seneca, SC 29678
    View details
    Surfside Beach Freestanding Office Building
    $2,500 / Mo
    1,100 SF

    Surfside Beach Freestanding Office Building

    Freestanding office building for lease in downtown Surfside Beach.

    825 1St Ave N, Surfside Beach, SC 29575
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    Renovated Office Space For Rent
    $1,600 / Mo

    Renovated Office Space For Rent

    Newly renovated 650 SF office space with utilities included.

    1 Merchants Ln, Ladys Island, SC 29907
    View details
    Office Warehouse in Murrells Inlet
    $3,000 / Mo
    2,200 SF

    Office Warehouse in Murrells Inlet

    Office warehouse space for lease with great location and visibility.

    11772 S Highway 17 Byp, Murrells Inlet, SC 29576
    View details

    South Carolina Commercial real estate Leasing Opportunities Market Analysis

    Explore Commercial real estate leasing options in South Carolina with 5000+ listings featured on our commercial real estate exchange. The current inventory includes 1,512,396,378,306 square feet of properties with an estimated lease value of $283,761.

    Estimated lease rates for Commercial real estate in South Carolina begin at $0.51 SF/Yr, with an average of $261 SF/Yr and extend to $66,000.
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