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    South Carolina Commercial Real Estate for Lease

    3,147 results
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    High-Visibility Gas Station & Store
    $23 SF/Yr
    52,272 SF

    High-Visibility Gas Station & Store

    5 Lane St, Yemassee, SC 29945

    Gas station and convenience store with high visibility and traffic.

    • High‑visibility location directly off I‑95 (Exit 38) with 41,992 daily traffic count.
    • Move‑in‑ready gas station and convenience store suitable for immediate operation.
    • Strategic location between Charleston, Hilton Head, and Savannah, serving tourists, commuters, and long‑haul drivers.
    • Direct access to I‑95 southbound and excellent highway visibility.
    • 5,413‑square‑foot convenience store with an open floor plan for flexible merchandising.
    Updated: Jan 17
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    Premier Commercial Space on Lady's Island
    $4,500 / Mo
    1,307 SF

    Premier Commercial Space on Lady's Island

    8 Celadon Dr, Beaufort, SC 29907

    High-visibility commercial space for lease on Lady's Island.

    • Maximum visibility and dedicated signage on Sam's Point Road, the main commercial artery of Lady's Island, offering high daily traffic flow.
    • Versatile, open‑concept layout with approximately 2,250 sq ft of modern, high‑end commercial space suitable for customization.
    • Modified Gross Lease at $4,500/month includes HOA, property taxes, building insurance, water, and trash collection, providing predictable budgeting.
    • Two‑story building with distinct ground floor (open floor plan, concrete floors) and upper floor (mix of offices, kitchenette, private entrance) spaces.
    • Ideal for medical/dental/wellness practices, high‑end retail/showrooms, professional services, or creative agencies.
    Updated: Jan 16
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    High Visibility Retail Space Available
    $1,950 / Mo
    1,250 SF

    High Visibility Retail Space Available

    Retail space in high-traffic area, ready for your business.

    12270 Highway 17 Byp, Murrells Inlet, SC 29576
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    Downtown Anderson Commercial Space Available
    $1,350 / Mo
    2,614 SF

    Downtown Anderson Commercial Space Available

    Versatile 1,300 SF space in historic downtown Anderson.

    122 W Whitner St, Anderson, SC 29624
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    Commercial Space on Sea Island Parkway
    $2,750 / Mo
    2,178 SF

    Commercial Space on Sea Island Parkway

    Commercial space with high visibility near Fripp and Hunting Islands.

    2123 Sea Island Pkwy, Saint Helena Island, SC 29920
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    Commercial Space on Harbor Island
    $1,200 / Mo
    436 SF

    Commercial Space on Harbor Island

    Commercial property with high visibility near Fripp and Hunting Islands.

    2123 Sea Is Pkwy Unit, Saint Helena Island, SC 29920
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    Salon Suite in Port Royal
    $625 / Mo

    Salon Suite in Port Royal

    Move-in ready salon suite with utilities and Wi-Fi included.

    2206 Mossy Oaks Rd, Port Royal, SC 29935
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    Harbor Island Commercial Office Space
    $450 / Mo
    436 SF

    Harbor Island Commercial Office Space

    Office space available on Harbor Island, excellent visibility and access.

    2123 Sea Island Pkwy, Saint Helena Island, SC 29920
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    Port Royal Office/Creative Space
    $1,250 / Mo
    871 SF

    Port Royal Office/Creative Space

    Renovated 750 SF office/creative space in iconic Arts Building.

    1404 Paris Ave, Port Royal, SC 29935
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    Commercial Space on Lady's Island
    $575 / Mo

    Commercial Space on Lady's Island

    Multi-tenant commercial building near downtown Beaufort and Beaufort High School.

    9a Rue Du Bois, Ladys Island, SC 29907
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    Downtown Beaufort Office Space
    $1,100 / Mo
    436 SF

    Downtown Beaufort Office Space

    Charming office space in downtown Beaufort with waterfront views.

    1011 Bay St, Beaufort, SC 29902
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    Salon Suite in Port Royal
    $625 / Mo

    Salon Suite in Port Royal

    80 sq ft salon suite available for rent.

    2206 Mossy Oaks Rd, Port Royal, SC 29935
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    Lady's Island Multi-Use Space
    $750 / Mo

    Lady's Island Multi-Use Space

    Multi-use commercial space available on Lady's Island, SC.

    9 Rue Du Bois, Ladys Island, SC 29907
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    Office/Storage Space with Land
    $1,000 / Mo
    1,307 SF

    Office/Storage Space with Land

    Commercial office/storage space with ample land in Beaufort, SC.

    40 Shanklin Rd, Beaufort, SC 29906
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    Renovated Office Space Available
    $1,900 / Mo
    436 SF

    Renovated Office Space Available

    Newly renovated 650 SF office space in Lady's Island.

    1 Merchants Ln, Ladys Island, SC 29907
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    Aiken Office Space For Lease
    $3,772 / Mo
    1,886 SF

    Aiken Office Space For Lease

    New build-out opportunity for office or medical space in Aiken.

    148 SW Unit, Aiken, SC 29801
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    Prime Retail Space in Aynor
    $2,009 / Mo
    1,507 SF

    Prime Retail Space in Aynor

    1,507 sq ft retail space in growing Aynor, SC.

    905 N Main St, Aynor, SC 29511
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    Wagener Loft Space For Rent
    $1,495 / Mo
    1,375 SF

    Wagener Loft Space For Rent

    Versatile loft in downtown Wagener, suitable for residential or commercial.

    108 Park St NW, Wagener, SC 29164
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    Renovated Office Space Available
    $2,075 / Mo
    1,120 SF

    Renovated Office Space Available

    Newly renovated office space for lease in Aiken, South Carolina.

    410 University Pkwy Unit, Aiken, SC 29801
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    Downtown Wagener Commercial Space Available
    $1,695 / Mo
    1,375 SF

    Downtown Wagener Commercial Space Available

    Premier commercial space in downtown Wagener, move-in ready and versatile.

    108 Park St NW, Wagener, SC 29164
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    Warehouse with Office and Yard
    $3,750 / Mo
    10,500 SF

    Warehouse with Office and Yard

    10500 sq ft warehouse with offices, loading dock, fenced yard.

    30 Bridge Ct, Sumter, SC 29150
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    Office Space in Marion, SC
    $1,000 / Mo
    2,000 SF

    Office Space in Marion, SC

    Office space featuring a reception area, offices, and conference room.

    1450 E Northside Ave, Marion, SC 29571
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    Office Space Near Timrod Park
    $700 / Mo
    150 SF

    Office Space Near Timrod Park

    Flexible office spaces in historic building near Timrod Park.

    720 S Coit St, Florence, SC 29501
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    Versatile Commercial Space in Florence
    $5,000 / Mo
    11,390 SF

    Versatile Commercial Space in Florence

    Commercial property with bay doors, ideal for automotive or warehouse.

    374 Darlington St, Florence, SC 29501
    View details

    South Carolina Commercial Real Estate Leasing Opportunities Market Analysis

    Explore Commercial Real Estate leasing options in South Carolina with 5000+ listings featured on our commercial real estate exchange. The current inventory includes 2,076,472,537,953 square feet of properties with an estimated lease value of $737,983.

    Estimated lease rates for Commercial Real Estate in South Carolina begin at $0.53 SF/Yr, with an average of $423 /Mo and extend to $84,000.

    In South Carolina, current lease rates show:

    • Office Properties & Spaces positioned at $153
    • Retail properties measuring $255
    • Office space assessed at $39
    • Industrial properties calculated at $541
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