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South Carolina Commercial Real Estate for Lease

3,147 results
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Downtown Anderson Commercial Space Available
$1,350 / Mo
2,614 SF

Downtown Anderson Commercial Space Available

122 W Whitner St, Anderson, SC 29624

Versatile 1,300 SF space in historic downtown Anderson.

  • Prime location in historic downtown Anderson, across from the Anderson County Courthouse.
  • Versatile 1,300 square‑foot upper‑level space suitable for office, retail, or studio.
  • Adjacent to the City Parking Garage with ample street parking available.
  • Wood flooring throughout.
  • Adaptable floor plan.
Updated: Jan 15
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Commercial Space on Sea Island Parkway
$2,750 / Mo
2,178 SF

Commercial Space on Sea Island Parkway

2123 Sea Island Pkwy, Saint Helena Island, SC 29920

Commercial space with high visibility near Fripp and Hunting Islands.

  • Prime commercial location on Sea Island Parkway offering high visibility.
  • Close proximity to Fripp Island (5 miles) and Hunting Island (under 1 mile).
  • Ample parking for clients and employees.
  • Basement currently occupied by a vacation rental business (can vacate if needed).
  • Separate entrance/exit for basement tenant.
Updated: Jan 15
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Commercial Space on Harbor Island
$1,200 / Mo
436 SF

Commercial Space on Harbor Island

Commercial property with high visibility near Fripp and Hunting Islands.

2123 Sea Is Pkwy Unit, Saint Helena Island, SC 29920
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Salon Suite in Port Royal
$625 / Mo

Salon Suite in Port Royal

Move-in ready salon suite with utilities and Wi-Fi included.

2206 Mossy Oaks Rd, Port Royal, SC 29935
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Harbor Island Commercial Office Space
$450 / Mo
436 SF

Harbor Island Commercial Office Space

Office space available on Harbor Island, excellent visibility and access.

2123 Sea Island Pkwy, Saint Helena Island, SC 29920
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Port Royal Office/Creative Space
$1,250 / Mo
871 SF

Port Royal Office/Creative Space

Renovated 750 SF office/creative space in iconic Arts Building.

1404 Paris Ave, Port Royal, SC 29935
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Commercial Space on Lady's Island
$575 / Mo

Commercial Space on Lady's Island

Multi-tenant commercial building near downtown Beaufort and Beaufort High School.

9a Rue Du Bois, Ladys Island, SC 29907
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Downtown Beaufort Office Space
$1,100 / Mo
436 SF

Downtown Beaufort Office Space

Charming office space in downtown Beaufort with waterfront views.

1011 Bay St, Beaufort, SC 29902
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Salon Suite in Port Royal
$625 / Mo

Salon Suite in Port Royal

80 sq ft salon suite available for rent.

2206 Mossy Oaks Rd, Port Royal, SC 29935
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Lady's Island Multi-Use Space
$750 / Mo

Lady's Island Multi-Use Space

Multi-use commercial space available on Lady's Island, SC.

9 Rue Du Bois, Ladys Island, SC 29907
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Office/Storage Space with Land
$1,000 / Mo
1,307 SF

Office/Storage Space with Land

Commercial office/storage space with ample land in Beaufort, SC.

40 Shanklin Rd, Beaufort, SC 29906
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Renovated Office Space Available
$1,900 / Mo
436 SF

Renovated Office Space Available

Newly renovated 650 SF office space in Lady's Island.

1 Merchants Ln, Ladys Island, SC 29907
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Aiken Office Space For Lease
$3,772 / Mo
1,886 SF

Aiken Office Space For Lease

New build-out opportunity for office or medical space in Aiken.

148 SW Unit, Aiken, SC 29801
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Prime Retail Space in Aynor
$2,009 / Mo
1,507 SF

Prime Retail Space in Aynor

1,507 sq ft retail space in growing Aynor, SC.

905 N Main St, Aynor, SC 29511
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Wagener Loft Space For Rent
$1,495 / Mo
1,375 SF

Wagener Loft Space For Rent

Versatile loft in downtown Wagener, suitable for residential or commercial.

108 Park St NW, Wagener, SC 29164
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Renovated Office Space Available
$2,075 / Mo
1,120 SF

Renovated Office Space Available

Newly renovated office space for lease in Aiken, South Carolina.

410 University Pkwy Unit, Aiken, SC 29801
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Downtown Wagener Commercial Space Available
$1,695 / Mo
1,375 SF

Downtown Wagener Commercial Space Available

Premier commercial space in downtown Wagener, move-in ready and versatile.

108 Park St NW, Wagener, SC 29164
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Warehouse with Office and Yard
$3,750 / Mo
10,500 SF

Warehouse with Office and Yard

10500 sq ft warehouse with offices, loading dock, fenced yard.

30 Bridge Ct, Sumter, SC 29150
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Office Space in Marion, SC
$1,000 / Mo
2,000 SF

Office Space in Marion, SC

Office space featuring a reception area, offices, and conference room.

1450 E Northside Ave, Marion, SC 29571
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Office Space Near Timrod Park
$700 / Mo
150 SF

Office Space Near Timrod Park

Flexible office spaces in historic building near Timrod Park.

720 S Coit St, Florence, SC 29501
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Versatile Commercial Space in Florence
$5,000 / Mo
11,390 SF

Versatile Commercial Space in Florence

Commercial property with bay doors, ideal for automotive or warehouse.

374 Darlington St, Florence, SC 29501
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Houndslake Office Space for Lease
$534 / Mo
113 SF

Houndslake Office Space for Lease

Office spaces available in Houndslake Country Club, Aiken, SC.

918 Houndslake Dr, Aiken, SC 29803
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Retail Space in Sumter, SC
$900 / Mo
932 SF

Retail Space in Sumter, SC

Open retail space available for rent in a strip mall.

632 W Liberty St, Sumter, SC 29150
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Myrtle Beach Office and Warehouse
$5,000 / Mo
6,000 SF

Myrtle Beach Office and Warehouse

6,000 SF office and warehouse space with versatile layout.

106 Lichen Ct, Myrtle Beach, SC 29588
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South Carolina Commercial Real Estate Leasing Opportunities Market Analysis

Explore Commercial Real Estate leasing options in South Carolina with 5000+ listings featured on our commercial real estate exchange. The current inventory includes 2,076,472,537,953 square feet of properties with an estimated lease value of $737,983.

Estimated lease rates for Commercial Real Estate in South Carolina begin at $0.53 SF/Yr, with an average of $423 /Mo and extend to $84,000.

In South Carolina, current lease rates show:

  • Office Properties & Spaces positioned at $153
  • Retail properties measuring $255
  • Office space assessed at $39
  • Industrial properties calculated at $541
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