Johns Island, SC Commercial real estate for Rent & Lease

Updated: Jun 2

Eco-Friendly Office Park Suite

3417 Maybank Highway, Johns Island, SC 29455

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3,264 sqft

Four‑building office park with eco‑friendly design
Year built: 2017
Located on Maybank Highway on Johns Island
Available office space ranges from 1,488 to 3,264 SF
Spaces available in Buildings C & D

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Updated: Mar 6

Flex Warehouse Space For Lease

636 Main Rd, Johns Island, SC 29455

$18 SF/Yr

19,600 sqft 21.00 AC lot

Rare flex space for lease on Johns Island.
Units available from ±1,400 SF up to ±19,600 SF.
Anticipated delivery in Q4 of 2025.
Located in the Rural Commercial Overlay District.
Each unit includes two offices, one restroom, and one 10'x10' overhead door.

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Office/Retail Suite with Monument Signage

3430 Maybank Hwy, Johns Island, SC 29455

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1,000 sqft

Bright 1,000 SF suite along Maybank Highway with monument signage and ample on-site parking.

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Class A Executive Office Suite

3425 Maybank Hwy, Johns Island, SC 29455

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1,776 sqft

Well-appointed Class A executive suite within a landscaped office park, offering shared conference and reception amenities.

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Open Layout Office Studio

1715 Hollydale Ct, Johns Island, SC 29455

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2,000 sqft

Flexible open-plan suite formerly used as an indoor fitness studio, well-suited for a range of general office uses.

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Corner Retail Space

2831 Maybank Hwy, Johns Island, SC 29455

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1,362 sqft

Retail space is available within a General Business-zoned development in the City of Charleston.

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Functional Space in Sea Island

3609 River Road, Johns Island, SC 29455

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2,710 sqft

2,710 SF warehouse and office space for lease.

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Warehouse-Flex Suite with Drive-In Doors

3609 River Road, Johns Island, SC 29455

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4,610 sqft

Renovated suite includes a warehouse-flex layout with two drive-in doors, restroom and office space.

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Retail Space in Johns Island

3874 Savannah Hwy, Johns Island, SC

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1,200 sqft 1.34 AC lot

Retail space for lease in a bustling commercial district.

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Flexible Space on Johns Island

860 Main Rd, Johns Island, SC 29455

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9,150 sqft

Adaptable warehousing, office, and showroom space available for lease.

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Renovated Office Space Available

900 Main Rd, Johns Island, SC

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960 sqft 1.88 AC lot

960 SF office space with excellent visibility.

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Secured Industrial Laydown Yard

771 Brownswood Rd, Johns Island, SC 29455

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1.50 AC lot

Secured industrial land offered for laydown use, zoned BP Business Park, with perimeter fencing and renovation underway.

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Maybank Highway Development Opportunity

Tallent Ln, Johns Island, SC

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58,136 sqft 14.48 AC lot

New construction opportunity for medical, professional office, or retail.

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Based on your search, we've compiled 33 Potential Opportunities for your consideration. Besides 13 Active listings in Johns Island, SC, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 16 Properties for Sales.

Commercial real estate for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Renovated Flex Space with Open Layout

2467 Savannah Hwy, Charleston, SC 29414

$1,900/Mo

3,704 sqft

Open-plan suites include bathrooms and a break area.

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Freestanding Retail or Office Building

625 Skylark Drive, Charleston, SC 29407

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3,925 sqft

Freestanding building with strong signage visibility, positioned near major retail corridors for flexible retail or office use.

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Shopping Center Retail Units for Lease

2049 Savannah Highway, Charleston, SC 29407

$20-$22 SF/Yr

Two retail suites available at West Island Center with direct access to Savannah Highway and convenient access to I-526.

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Retail Space in Quadrangle Center

630 Skylark Drive, Charleston, SC 29407

$25 SF/Yr

1,040 SF available in West Ashley shopping center.

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Similar Spaces for Sale in Johns Island, SC

Consider Similar Space for Sale. We found 16 Spaces matching your search parameters.

Corner Commercial Lot with Building

571 Main Road, Johns Island, SC 29455

$350,000

896 sqft 0.33 AC lot

Zoned Rural Commercial corner lot with 293 ft Main Rd and 153 ft Old Pond Road frontage.

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Commercial Land Tract

3993 Betsy Kerrison Parkway, Johns Island, SC 29455

$1,495,000

3.33 AC lot

Commercial land near Kiawah and Seabrook Islands, Freshfields Village, and South Island Market.

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Commercial Land with Highway Frontage

Johns Island, SC 29455

$840,000

1.03 AC lot

Development-focused land site with Savannah Highway frontage and utility availability for future commercial use planning.

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Commercial Land with Highway Frontage

3820 Savannah Highway, Johns Island, SC 29455

$840,000

1.03 AC lot

Parcel with utility availability along Savannah Highway, subject to verification and county approval for commercial zoning.

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Approved Assisted Living Development Site

692 Bear Swamp Road, Johns Island, SC 29455

$285,000

2.30 AC lot

Commercial land in a planned unit development area with approval for an assisted living facility.

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Cleared Pasture Land Parcel

000 Brewton, Johns Island, SC 29455

$400,000

125,453 sqft

Mostly cleared pasture land near the Kiawah River, with an access requirement from Rosas Ln if purchased alone.

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Commercial Land With Road Frontage

3528 River Road, Johns Island, SC 29455

$299,000

2.20 AC lot

Commercial parcel along River Road with frontage, access, and potential for several development formats subject to zoning.

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Commercial Land Parcel

4011 Betsy Kerrison Parkway, Johns Island, SC 29455

$1,495,000

3.33 AC lot

Commercial land positioned near established residential, recreational, and commercial destinations.

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Johns Island Marsh Front Acreage

3505 Legareville Rd, Johns Island, SC 29455

$675,000

9.69 AC lot

Rare dockable acreage ideal for a dream home or hobby farm.

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Entitled Flex Space Redevelopment

771 Brownswood Rd, Johns Island, SC 29455

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41,000 sqft

Fully entitled redevelopment site with approved construction plans and outdoor storage capacity.

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Office Buildings with Rear Outbuilding

3461 Maybank Highway, Johns Island, SC 29455

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1,800 sqft 1.15 AC lot

CT-zoned commercial property with two existing buildings, multiple permitted use categories, and room for future expansion.

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