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    Johns Island, SC Commercial Real Estate for Lease

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    Columbia, SC Greenville, SC Charleston, SC
    21 results
    Functional Space in Sea Island
    $12 SF/Yr
    2,710 SF

    Functional Space in Sea Island

    3609 River Road, Johns Island, SC 29455

    2,710 SF warehouse and office space for lease.

    • Functional space with 2,710 SF including warehouse and office area.
    • Convenient access to Freshfields Village, downtown Charleston, and the airport.
    • Warehouse includes two drive‑in doors.
    • Located in Sea Island Business Park.
    • Less than 9 miles from Kiawah and Seabrook Islands.
    Updated: Mar 25
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    Flex Warehouse Space For Lease
    $18 SF/Yr
    19,600 SF

    Flex Warehouse Space For Lease

    636 Main Rd, Johns Island, SC 29455

    Flex warehouse space for lease on Johns Island.

    • Rare flex space for lease on Johns Island.
    • Units available from ±1,400 SF up to ±19,600 SF.
    • Anticipated delivery in Q4 of 2025.
    • Located in the Rural Commercial Overlay District.
    • Each unit includes two offices, one restroom, and one 10'x10' overhead door.
    Updated: Mar 6
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    Flex Warehouse Space For Lease
    $18 SF/Yr
    19,600 SF

    Flex Warehouse Space For Lease

    Flex warehouse space for lease on Johns Island.

    636 Main Rd, Johns Island, SC 29455
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    Flexible Space on Johns Island
    $14 SF/Yr
    108,848 SF

    Flexible Space on Johns Island

    Adaptable warehousing, office, and showroom space available for lease.

    860 Main Road, Johns Island, SC 29455
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    Retail Space in Johns Island
    $15 SF/Yr
    1,200 SF

    Retail Space in Johns Island

    Retail space for lease in a bustling commercial district.

    3874 Savannah Hwy, Johns Island, SC
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    Showroom and Office Space
    $30 SF/Yr
    1,000 SF

    Showroom and Office Space

    1,000 SF showroom/office space on Maybank Highway for rent.

    3436 Maybank Hwy, Johns Island, SC
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    Johns Island Office Space Available
    $16 SF/Yr
    5,880 SF

    Johns Island Office Space Available

    Office space available for lease in Johns Island, SC.

    1810 Paulette Dr, Johns Island, SC
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    Retail and Service Opportunity
    Contact for pricing
    6,400 SF

    Retail and Service Opportunity

    Land and retail spaces for lease on Main Road.

    685 Main Road, Johns Island, SC 29455
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    Renovated Office Space Available
    $17 SF/Yr
    960 SF

    Renovated Office Space Available

    960 SF office space with excellent visibility.

    900 Main Rd, Johns Island, SC
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    Johns Island Office Suite
    $30 SF/Yr
    550 SF

    Johns Island Office Suite

    550 SF office suite in the heart of Johns Island.

    3546 Maybank Hwy, Johns Island, SC
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    Move-in Ready Office Space
    $25 SF/Yr
    1,885 SF

    Move-in Ready Office Space

    Move-in ready office space in Live Oak Square.

    1814 Crowne Commons Way, Johns Island, SC
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    Johns Island Retail/Office Space
    Contact for pricing

    Johns Island Retail/Office Space

    Newly renovated retail, office, or restaurant space on Johns Island.

    3575 Maybank Highway # P, Johns Island, SC 29455
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    Johns Island Freestanding Building
    $25 SF/Yr
    5,000 SF

    Johns Island Freestanding Building

    Move-in ready 5,000 SF building on Johns Island.

    3600 J Henry Cut, Johns Island, SC
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    Retail Space in Johns Island
    Contact for pricing
    3,005 SF

    Retail Space in Johns Island

    Retail space available for lease in Johns Island, SC.

    165 Village Green Dr, Johns Island, SC
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    Maybank Highway Retail/Office Opportunity
    $30 SF/Yr
    3,929 SF

    Maybank Highway Retail/Office Opportunity

    New construction opportunity on Maybank Highway in rapidly expanding Johns Island.

    Southwind Station Maybank Hwy, Johns Island, SC
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    Johns Island Retail Space
    Contact for pricing
    3,037 SF

    Johns Island Retail Space

    Retail space available for lease in Johns Island, SC.

    649 Freshfields Dr, Johns Island, SC
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    Medical/Professional Office Space Available
    $30 SF/Yr
    4,211 SF

    Medical/Professional Office Space Available

    Single-story office space ready for upfits near new developments.

    2947 Maybank Hwy, Johns Island, SC
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    Maybank Highway Development Opportunity
    $40 SF/Yr
    58,136 SF

    Maybank Highway Development Opportunity

    New construction opportunity for medical, professional office, or retail.

    Tallent Ln, Johns Island, SC
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    Retail Space Near Planned Development
    Contact for pricing

    Retail Space Near Planned Development

    Retail space bordering Long Savanna development, near US Hwy-17.

    1198 Bees Ferry Rd, Johns Island, SC 29455
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    Maybank Highway Commercial Space
    Contact for pricing
    58,136 SF

    Maybank Highway Commercial Space

    New construction with space for medical, office, or retail.

    Maybank Hwy, Johns Island, SC 29455
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    Publix Anchored Retail Center
    Contact for pricing
    58,841 SF

    Publix Anchored Retail Center

    58,841 SF retail center with national and local tenants.

    3642 Savannah Hwy, Johns Island, SC 29455
    View details
    Based on your search, we've compiled 43 Potential Opportunities for your consideration. Besides 21 Active listings in Johns Island, SC, we suggest exploring alternatives. Similar 22 Properties for Sales.

    Explore Similar Spaces for Sale in Johns Island, SC

    Consider Similar Space for Sale. We found 22 Spaces matching your search parameters.

    Johns Island Commercial Development Opportunity
    $1,250,000
    2.00 Acres

    Johns Island Commercial Development Opportunity

    Permit-ready 1.99-acre corner parcel for office development on Johns Island.

    2729 Bohicket Road, Johns Island, SC 29455
    View details
    Johns Island Acreage Opportunity
    $2,200,000
    6.45 Acres

    Johns Island Acreage Opportunity

    6.45 acres on Betsy Kerrison Parkway, Johns Island.

    4131 Betsy Kerrison Parkway, Johns Island, SC 29455
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    Johns Island Marsh Front Acreage
    $675,000
    9.69 Acres

    Johns Island Marsh Front Acreage

    Rare dockable acreage ideal for a dream home or hobby farm.

    3505 Legareville Road, Johns Island, SC 29455
    View details

    Johns Island, SC Commercial real estate Leasing Opportunities Market Analysis

    Explore Commercial real estate leasing options in Johns Island, SC with 21 listings featured on our commercial real estate exchange. The current inventory includes 5,862,871,080 square feet of properties with an estimated lease value of $129 SF/Yr.

    Estimated lease rates for Commercial real estate in Johns Island, SC begin at $12 SF/Yr, with an average of $21 SF/Yr and extend to $30 SF/Yr.
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