Mount Pleasant, SC Commercial Real Estate for Lease

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81 properties
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Gregorie Ferry Landing
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Furnished Executive Corner Office
Updated: Jul 13
Furnished Executive Corner Office

10 Shem Drive 100-E, Mount Pleasant, SC 29464

$136/Mo
Year built 2021 executive office space in the Coleman Blvd. business district
Office E is an approximately 11' x 10' corner office with multiple windows
Offered at $1,250 per month on a full‑service executive office sublease
Lease includes all utilities and high‑speed internet
Includes on‑site parking plus access to a shared conference room, shared kitchenette, and shared main lobby
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Furnished Executive Office Suite
Updated: Jul 13
Furnished Executive Office Suite

10 Shem Drive 100-C, Mount Pleasant, SC 29464

$177/Mo
Class A furnished executive office built in 2021 in the Coleman Blvd. business district
Office C with a window offers approximately 11' x 6' workspace
Lease at $975/month includes all utilities and high‑speed internet access
Full‑service lease includes on‑site parking plus access to a shared conference room, shared kitchenette, and shared main lobby
Private office has 9‑foot ceilings; main lobby has 11‑foot ceilings
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Retail Storefront Property
Retail Storefront Property

627 Hwy 17 N, Mount Pleasant, SC 29466

$32/Mo

For rent retail storefront on a major highway with a sizable 9.01-acre lot for flexible site planning.

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Class A Flex Space Available
Class A Flex Space Available

547 Long Point Road, Mount Pleasant, SC 29464

$20 SF/Yr
4,380 sqft

Flex space with showroom/office and warehouse, convenient location.

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Mount Pleasant Office Space Available
Mount Pleasant Office Space Available

1671 Belle Isle Avenue, Mount Pleasant, SC 29464

$26 SF/Yr
2,227 sqft

Office space available for lease in Mount Pleasant, SC.

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Office Space Near Shopping Center
Office Space Near Shopping Center

1004 Anna Knapp Blvd, Mount Pleasant, SC 29464

$1,300/Mo
204 sqft

Second-floor office space with natural light and free parking.

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Mount Pleasant Retail Space Available
Mount Pleasant Retail Space Available

543 Long Point Road, Mount Pleasant, SC 29464

$24 SF/Yr
5,250 sqft

Retail space in prime Mount Pleasant location, available June 1, 2026.

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Class A Medical Office Building
Class A Medical Office Building

1200 Innovation Way, Mount Pleasant, SC 29466

$28 SF/Yr
14,084 sqft

Renovated medical/office building with ample parking in Mt. Pleasant.

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Retail Space in Mt. Pleasant
Retail Space in Mt. Pleasant

2700 Brickyard Parkway, Mount Pleasant, SC 29466

$28 SF/Yr
3,689 sqft

Retail space for lease in The Shoppes at Brickyard.

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Mount Pleasant Retail/Office/Medical Space
Mount Pleasant Retail/Office/Medical Space

1123 Queensborough Boulevard, Mount Pleasant, SC 29464

$30 SF/Yr
3,949 sqft

3,949 SF space ideal for retail, office, or medical.

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Medical Office in Mt. Pleasant
Medical Office in Mt. Pleasant

1300 Hospital Dr, Mount Pleasant, SC 29464

$34 SF/Yr
60,809 sqft

Medical office space available for sublease in Mt. Pleasant.

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Renovated Shopping Center on Hwy 17
Renovated Shopping Center on Hwy 17

627 Johnnie Dodds Blvd, Mount Pleasant, SC 29464

$32 SF/Yr
103,036 sqft

Highly visible, renovated shopping center with frontage on Hwy 17.

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Mt. Pleasant Retail Space Available
Mt. Pleasant Retail Space Available

2195 Tea Planters Ln, Mount Pleasant, SC

$35 SF/Yr
2,975 sqft

Retail space for lease in Harris Teeter anchored shopping center.

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Bowman Place Retail Outparcel
Bowman Place Retail Outparcel

1132 Bowman Rd, Mount Pleasant, SC

$53 SF/Yr
1,500 sqft

Retail outparcel in Mt. Pleasant's premier retail destination.

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Mount Pleasant Office Space Available
Mount Pleasant Office Space Available

880 Johnnie Dodds Boulevard, Mount Pleasant, SC 29464

$28 SF/Yr
2,400 sqft

Office space available for lease in Mount Pleasant, SC.

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Mount Pleasant Office Space Available
Mount Pleasant Office Space Available

790 Johnnie Dodds Blvd, Mount Pleasant, SC

$30 SF/Yr
3,400 sqft

3,400 SF office space with ample parking and signage.

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Freestanding Office Building For Lease
Freestanding Office Building For Lease

890 JOHNNIE DODDS BLVD, Mount Pleasant, SC

$20.50 SF/Yr
3,400 sqft

Two-story office property in a rapidly developing commercial corridor.

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Single-Story Office in Wando Commons
Single-Story Office in Wando Commons

498 Wando Park Blvd, Mount Pleasant, SC

$24 SF/Yr
2,263 sqft

Single-story office space with convenient access to major routes.

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Class A Office Space Available
Class A Office Space Available

Bridgeside Blvd, Mount Pleasant, SC

$45 SF/Yr
3,700 sqft

Class A office space for rent in Mount Pleasant.

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Professional Office Building with Parking
Professional Office Building with Parking

845 Lowcountry Boulevard # A, Mount Pleasant, SC 29464

Contact for pricing
4,238 sqft

Office suites with windows, shared conference space, and free on-site parking in a high-visibility corridor.

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Retail Space in CVS-Anchored Center
Retail Space in CVS-Anchored Center

1405 Ben Sawyer Boulevard, Mount Pleasant, SC 29464

Contact for pricing
1,960 sqft

Well-located storefront space in an open-air retail center with strong visibility and flexible layout options.

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Mount Pleasant Office Condo For Lease
Mount Pleasant Office Condo For Lease

856 Lowcountry Boulevard, Mount Pleasant, SC 29464

Contact for pricing
2,880 sqft

Well-appointed office condo in central Mount Pleasant location.

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Retail/Office Space in Mount Pleasant
Retail/Office Space in Mount Pleasant

695 Johnnie Dodds Blvd, Mount Pleasant, SC

$35 SF/Yr
2,432 sqft

Highly visible retail/office space in the heart of Mount Pleasant.

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Dental-To-Medical Office Suite
Dental-To-Medical Office Suite

1065-C Johnnie Dodds Blvd, Mount Pleasant, SC 29464

Contact for pricing
1,500 sqft

Turn-key office currently set up for dental use, positioned across from a major hospital with convenient highway access.

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Mount Pleasant, SC Commercial real estate Market Trends and Statistics

Explore Commercial real estate leasing options in Mount Pleasant, SC with 81 listings featured on our commercial real estate exchange. The current inventory includes 303,484 square feet of properties with an estimated lease value of $954.10 /Mo.

Estimated lease rates for Commercial real estate in Mount Pleasant, SC begin at $12 SF/Yr, with an average of $36.70 SF/Yr and extend to $140.73 SF/Yr.
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