Mount Pleasant, SC
    For Lease
    • For Sale
    • For Lease
    • Recently Sold
    • Property Lookup
    • Brokers
    Space Uses
    • Retail
    • Restaurant
    • Office
    • Coworking
    • Medical Space
    • Automotive
    • Industrial
    • Warehouse
    • Flex
    • Hospitality
    • Sports & Entertainment
    • Specialty
    Rent
    Rent
    $
    $
    Size
    Property Size / SF

    Mount Pleasant, SC Commercial Real Estate for Lease

    Notify Me
    List
    Map
    Charleston, SC Wando, SC North Charleston, SC
    91 results
    Gregorie Ferry Landing
    View details
    Mount Pleasant Retail Space Available
    $24 SF/Yr
    5,250 SF

    Mount Pleasant Retail Space Available

    543 Long Point Road, Mount Pleasant, SC 29464

    Retail space in prime Mount Pleasant location, available June 1, 2026.

    • Prime location in Mount Pleasant with high visibility and easy access near Long Point Road and Belle Hall Parkway.
    • Spacious 5,250 RSF layout offering flexibility for various business needs; suites can be leased together or separately.
    • Versatile space suitable for retail, office, or service‑oriented businesses.
    • Ample parking for tenants and customers.
    • Modern architecture and well‑maintained exterior with ultra‑high ceilings.
    Updated: Mar 5
    View details
    Professional Office Space For Rent
    $895/Mo

    Professional Office Space For Rent

    845 Lowcountry Blvd, Mount Pleasant, SC 29464

    Prime location office building with walkable access to local favorites.

    • Prime location on Lowcountry Blvd with exceptional visibility and accessibility.
    • Free on‑site parking.
    • Walkable access to local favorites like Second State Coffee and Langdon’s Restaurant & Wine Bar.
    • Convenient access to Hwy 17.
    • Less than 10 minutes from downtown Charleston or the beach.
    Updated: Mar 7
    View details
    Retail Space in Mt. Pleasant
    $28 SF/Yr
    3,689 SF

    Retail Space in Mt. Pleasant

    Retail space for lease in The Shoppes at Brickyard.

    2700 Brickyard Parkway, Mount Pleasant, SC 29466
    View details
    Office Space Near Shopping Center
    $1,300/Mo

    Office Space Near Shopping Center

    Second-floor office space with natural light and free parking.

    1004 Anna Knapp Blvd, Mount Pleasant, SC 29464
    View details
    Class A Medical Office Building
    $28 SF/Yr
    14,084 SF

    Class A Medical Office Building

    Renovated medical/office building with ample parking in Mt. Pleasant.

    1200 Innovation Way, Mount Pleasant, SC 29466
    View details
    Mount Pleasant Office Space Available
    $895/Mo

    Mount Pleasant Office Space Available

    Office space for rent with parking, Wi-Fi, and conference room.

    845 Lowcountry Blvd, Mount Pleasant, SC 29464
    View details
    Class A Office Condo
    $22 SF/Yr
    2,000 SF

    Class A Office Condo

    High-end office condo available for lease in Mt. Pleasant.

    505 Belle Hall Parkway, Mount Pleasant, SC 29464
    View details
    Office Suite in Mt. Pleasant
    $30 SF/Yr
    1,245 SF

    Office Suite in Mt. Pleasant

    Office suite with private offices, reception, and conference room.

    782 Johnnie Dodds Boulevard #E, Mount Pleasant, SC 29464
    View details
    Medical Office in Mt. Pleasant
    $34 SF/Yr
    60,809 SF

    Medical Office in Mt. Pleasant

    Medical office space available for sublease in Mt. Pleasant.

    1300 Hospital Dr, Mount Pleasant, SC 29464
    View details
    Highway 17 North Development Site
    $40 SF/Yr
    8,250 SF

    Highway 17 North Development Site

    Land approved for retail/office development on Highway 17 North.

    3236 North Highway 17, Mount Pleasant, SC 29466
    View details
    Mount Pleasant Office Space Available
    $28 SF/Yr
    352 SF

    Mount Pleasant Office Space Available

    Office space in a well-maintained park with included utilities.

    503 Wando Park Blvd, Mount Pleasant, SC
    View details
    Mount Pleasant Office Space Available
    $26 SF/Yr
    2,227 SF

    Mount Pleasant Office Space Available

    Office space available for lease in Mount Pleasant, SC.

    1671 Belle Isle Avenue, Mount Pleasant, SC 29464
    View details
    Retail Land Lease Opportunity
    $95,000 SF/Yr
    46,114 SF

    Retail Land Lease Opportunity

    Retail land for lease in Mount Pleasant's shopping district.

    1734 N Highway 17, Mount Pleasant, SC 29464
    View details
    Multi-Tenant Office Building
    $26 SF/Yr

    Multi-Tenant Office Building

    Move-in ready office suites with first-floor lobby access, plus a second-floor option, with convenient shared parking onsite.

    1124 Park West Boulevard, Mount Pleasant, SC 29466
    View details
    New Office Building in Mount Pleasant
    $37 SF/Yr
    9,849 SF

    New Office Building in Mount Pleasant

    Newly constructed office building in desirable Mount Pleasant location.

    1681 Belle Isle Ave, Mount Pleasant, SC
    View details
    Renovated Shopping Center on Hwy 17
    $32 SF/Yr
    103,036 SF

    Renovated Shopping Center on Hwy 17

    Highly visible, renovated shopping center with frontage on Hwy 17.

    627 Johnnie Dodds Blvd, Mount Pleasant, SC 29464
    View details
    Single-Story Office in Wando Commons
    $24 SF/Yr
    2,263 SF

    Single-Story Office in Wando Commons

    Single-story office space with convenient access to major routes.

    498 Wando Park Blvd, Mount Pleasant, SC
    View details
    Retail Space Near Ravenel Bridge
    Contact for pricing
    863 SF

    Retail Space Near Ravenel Bridge

    Retail space in Whole Foods anchored shopping center available for lease.

    855 Houston Northcutt Blvd, Mount Pleasant, SC 29464
    View details
    Mount Pleasant Office Park Space
    Contact for pricing
    1,245 SF

    Mount Pleasant Office Park Space

    Office park with visibility, access, and nearby amenities for rent.

    782 Johnnie Dodds Boulevard, Mount Pleasant, SC 29464
    View details
    Mount Pleasant Office Space Available
    $28 SF/Yr
    2,400 SF

    Mount Pleasant Office Space Available

    Office space available for lease in Mount Pleasant, SC.

    880 Johnnie Dodds Boulevard, Mount Pleasant, SC 29464
    View details
    Mount Pleasant Office Space Available
    $30 SF/Yr
    3,400 SF

    Mount Pleasant Office Space Available

    3,400 SF office space with ample parking and signage.

    790 Johnnie Dodds Blvd, Mount Pleasant, SC
    View details
    Class A Flex Space
    Contact for pricing
    4,380 SF

    Class A Flex Space

    Flex building with showroom/office and fully conditioned warehouse space.

    547 Long Point Road # 104, Mount Pleasant, SC 29464
    View details
    Retail Space in CVS-Anchored Center
    Contact for pricing
    1,960 SF

    Retail Space in CVS-Anchored Center

    Well-located storefront space in an open-air retail center with strong visibility and flexible layout options.

    1405 Ben Sawyer Boulevard, Mount Pleasant, SC 29464
    View details

    Mount Pleasant, SC Commercial real estate Leasing Opportunities Market Analysis

    Explore Commercial real estate leasing options in Mount Pleasant, SC with 91 listings featured on our commercial real estate exchange. The current inventory includes 365,808 square feet of properties with an estimated lease value of $96,424.

    Estimated lease rates for Commercial real estate in Mount Pleasant, SC begin at $12 SF/Yr, with an average of $2,410 /Mo and extend to $95,000.
    List
    Map