Charleston County, SC Commercial Real Estate for Lease

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110 properties
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Gregorie Ferry Landing
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Furnished Executive Corner Office
Updated: Jul 13
Furnished Executive Corner Office

10 Shem Drive 100-E, Mount Pleasant, SC 29464

$136/Mo
Year built 2021 executive office space in the Coleman Blvd. business district
Office E is an approximately 11' x 10' corner office with multiple windows
Offered at $1,250 per month on a full‑service executive office sublease
Lease includes all utilities and high‑speed internet
Includes on‑site parking plus access to a shared conference room, shared kitchenette, and shared main lobby
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Furnished Executive Office Suite
Updated: Jul 13
Furnished Executive Office Suite

10 Shem Drive 100-C, Mount Pleasant, SC 29464

$177/Mo
Class A furnished executive office built in 2021 in the Coleman Blvd. business district
Office C with a window offers approximately 11' x 6' workspace
Lease at $975/month includes all utilities and high‑speed internet access
Full‑service lease includes on‑site parking plus access to a shared conference room, shared kitchenette, and shared main lobby
Private office has 9‑foot ceilings; main lobby has 11‑foot ceilings
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Retail Storefront Property
Retail Storefront Property

627 Hwy 17 N, Mount Pleasant, SC 29466

$32/Mo

For rent retail storefront on a major highway with a sizable 9.01-acre lot for flexible site planning.

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Class A Flex Space Available
Class A Flex Space Available

547 Long Point Road, Mount Pleasant, SC 29464

$20 SF/Yr
4,380 sqft

Flex space with showroom/office and warehouse, convenient location.

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Mount Pleasant Office Space Available
Mount Pleasant Office Space Available

1671 Belle Isle Avenue, Mount Pleasant, SC 29464

$26 SF/Yr
2,227 sqft

Office space available for lease in Mount Pleasant, SC.

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Office Space Near Shopping Center
Office Space Near Shopping Center

1004 Anna Knapp Blvd, Mount Pleasant, SC 29464

$1,300/Mo
204 sqft

Second-floor office space with natural light and free parking.

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Mount Pleasant Retail Space Available
Mount Pleasant Retail Space Available

543 Long Point Road, Mount Pleasant, SC 29464

$24 SF/Yr
5,250 sqft

Retail space in prime Mount Pleasant location, available June 1, 2026.

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Class A Medical Office Building
Class A Medical Office Building

1200 Innovation Way, Mount Pleasant, SC 29466

$28 SF/Yr
14,084 sqft

Renovated medical/office building with ample parking in Mt. Pleasant.

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Eco-Friendly Office Park Suite
Eco-Friendly Office Park Suite

3417 Maybank Highway, Johns Island, SC 29455

Contact for pricing
3,264 sqft

Office suites available in a four-building park with eco-friendly design and flexible space sizes.

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Retail Space in Mt. Pleasant
Retail Space in Mt. Pleasant

2700 Brickyard Parkway, Mount Pleasant, SC 29466

$28 SF/Yr
3,689 sqft

Retail space for lease in The Shoppes at Brickyard.

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Retail and Office Space Available
Retail and Office Space Available

4410 Savannah Hwy, Ravenel, SC 29470

$3,700/Mo
1,500 sqft

Retail and office spaces available for rent.

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Mount Pleasant Retail/Office/Medical Space
Mount Pleasant Retail/Office/Medical Space

1123 Queensborough Boulevard, Mount Pleasant, SC 29464

$30 SF/Yr
3,949 sqft

3,949 SF space ideal for retail, office, or medical.

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Class A Executive Office Suite
Class A Executive Office Suite

3425 Maybank Hwy, Johns Island, SC 29455

Contact for pricing
1,776 sqft

Well-appointed Class A executive suite within a landscaped office park, offering shared conference and reception amenities.

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Open Layout Office Studio
Open Layout Office Studio

1715 Hollydale Ct, Johns Island, SC 29455

Contact for pricing
2,000 sqft

Flexible open-plan suite formerly used as an indoor fitness studio, well-suited for a range of general office uses.

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Industrial Complex with Flexible Units
Industrial Complex with Flexible Units

4509 Savannah Highway, Ravenel, SC 29470

$15.50 SF/Yr
4,533 sqft

Multi-building industrial complex with modern construction and efficient layouts.

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Retail Space in Johns Island
Retail Space in Johns Island

3874 Savannah Hwy, Johns Island, SC

$15 SF/Yr
1,200 sqft

Retail space for lease in a bustling commercial district.

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Medical Office in Mt. Pleasant
Medical Office in Mt. Pleasant

1300 Hospital Dr, Mount Pleasant, SC 29464

$34 SF/Yr
60,809 sqft

Medical office space available for sublease in Mt. Pleasant.

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Renovated Shopping Center on Hwy 17
Renovated Shopping Center on Hwy 17

627 Johnnie Dodds Blvd, Mount Pleasant, SC 29464

$32 SF/Yr
103,036 sqft

Highly visible, renovated shopping center with frontage on Hwy 17.

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Mt. Pleasant Retail Space Available
Mt. Pleasant Retail Space Available

2195 Tea Planters Ln, Mount Pleasant, SC

$35 SF/Yr
2,975 sqft

Retail space for lease in Harris Teeter anchored shopping center.

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Bowman Place Retail Outparcel
Bowman Place Retail Outparcel

1132 Bowman Rd, Mount Pleasant, SC

$53 SF/Yr
1,500 sqft

Retail outparcel in Mt. Pleasant's premier retail destination.

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Mount Pleasant Office Space Available
Mount Pleasant Office Space Available

880 Johnnie Dodds Boulevard, Mount Pleasant, SC 29464

$28 SF/Yr
2,400 sqft

Office space available for lease in Mount Pleasant, SC.

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Flex Warehouse Space For Lease
Flex Warehouse Space For Lease

636 Main Rd, Johns Island, SC 29455

$18 SF/Yr
19,600 sqft

Flex warehouse space for lease on Johns Island.

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Mount Pleasant Office Space Available
Mount Pleasant Office Space Available

790 Johnnie Dodds Blvd, Mount Pleasant, SC

$30 SF/Yr
3,400 sqft

3,400 SF office space with ample parking and signage.

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Freestanding Office Building For Lease
Freestanding Office Building For Lease

890 JOHNNIE DODDS BLVD, Mount Pleasant, SC

$20.50 SF/Yr
3,400 sqft

Two-story office property in a rapidly developing commercial corridor.

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Charleston County, SC Commercial real estate Market Trends and Statistics

Explore Commercial real estate leasing options in Charleston County, SC with 110 listings featured on our commercial real estate exchange. The current inventory includes 584,150 square feet of properties with an estimated lease value of $1,322 /Mo.

Estimated lease rates for Commercial real estate in Charleston County, SC begin at $12 SF/Yr, with an average of $31.48 SF/Yr and extend to $140.73 SF/Yr.
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