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Charleston County, SC Commercial Real Estate for Lease

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116 results
Gregorie Ferry Landing
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Gregorie Ferry Landing

Discover many ways to work your way in Gregorie Ferry Landing

1240 Winnowing Way, Unit 100, Mount Pleasant, SC 29466
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Mount Pleasant Retail Space Available
$24 SF/Yr
5,250 SF

Mount Pleasant Retail Space Available

543 Long Point Road, Mount Pleasant, SC 29464

Retail space in prime Mount Pleasant location, available June 1, 2026.

  • Prime location in Mount Pleasant with high visibility and easy access near Long Point Road and Belle Hall Parkway.
  • Spacious 5,250 RSF layout offering flexibility for various business needs; suites can be leased together or separately.
  • Versatile space suitable for retail, office, or service‑oriented businesses.
  • Ample parking for tenants and customers.
  • Modern architecture and well‑maintained exterior with ultra‑high ceilings.
Updated: Mar 5
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Retail Space in Mt. Pleasant
$28 SF/Yr
3,689 SF

Retail Space in Mt. Pleasant

2700 Brickyard Parkway, Mount Pleasant, SC 29466

Retail space for lease in The Shoppes at Brickyard.

  • Extremely high traffic counts: 63,500 VPD on Hwy 17 N
  • Excellent central location serving the North Mt. Pleasant submarket
  • Located at the entrance of the Brickyard community in Mt. Pleasant
  • Great accessibility via lighted intersection to N. Highway 17
  • Available retail space: ±1,200‑3,689 SF
Updated: Mar 6
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Industrial Complex with Flexible Units
$15 SF/Yr
4,533 SF

Industrial Complex with Flexible Units

Multi-building industrial complex with modern construction and efficient layouts.

4509 Savannah Highway, Ravenel, SC 29470
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Class A Medical Office Building
$28 SF/Yr
14,084 SF

Class A Medical Office Building

Renovated medical/office building with ample parking in Mt. Pleasant.

1200 Innovation Way, Mount Pleasant, SC 29466
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Functional Space in Sea Island
$12 SF/Yr
2,710 SF

Functional Space in Sea Island

2,710 SF warehouse and office space for lease.

3609 River Road, Johns Island, SC 29455
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Medical Office in Mt. Pleasant
$34 SF/Yr
60,809 SF

Medical Office in Mt. Pleasant

Medical office space available for sublease in Mt. Pleasant.

1300 Hospital Dr, Mount Pleasant, SC 29464
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Highway 17 North Development Site
$40 SF/Yr
8,250 SF

Highway 17 North Development Site

Land approved for retail/office development on Highway 17 North.

3236 North Highway 17, Mount Pleasant, SC 29466
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Retail Pad Site with Drive-Thru
$125,000
3,050 SF

Retail Pad Site with Drive-Thru

Retail pad site with drive-thru potential on Long Point Road.

Mt Pleasant, SC 29464
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New Office Building in Mount Pleasant
$37 SF/Yr
9,849 SF

New Office Building in Mount Pleasant

Newly constructed office building in desirable Mount Pleasant location.

1681 Belle Isle Ave, Mount Pleasant, SC
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Renovated Shopping Center on Hwy 17
$32 SF/Yr
103,036 SF

Renovated Shopping Center on Hwy 17

Highly visible, renovated shopping center with frontage on Hwy 17.

627 Johnnie Dodds Blvd, Mount Pleasant, SC 29464
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Retail Pad Site with Drive-Thru
$125,000

Retail Pad Site with Drive-Thru

Retail pad site with drive-thru potential on Long Point Road.

Mt Pleasant, SC 29464
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Awendaw Flex Building For Lease
$5,833 /Mo
5,000 SF

Awendaw Flex Building For Lease

5,000 SF flex building on 0.5 acres available for lease.

6411 North Highway 17, Awendaw, SC 29429
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Flex Warehouse Space For Lease
$18 SF/Yr
19,600 SF

Flex Warehouse Space For Lease

Flex warehouse space for lease on Johns Island.

636 Main Rd, Johns Island, SC 29455
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Mount Pleasant Office Park Space
Contact for pricing
1,245 SF

Mount Pleasant Office Park Space

Office park with visibility, access, and nearby amenities for rent.

782 Johnnie Dodds Boulevard, Mount Pleasant, SC 29464
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Mount Pleasant Office Space Available
$30 SF/Yr
3,400 SF

Mount Pleasant Office Space Available

3,400 SF office space with ample parking and signage.

790 Johnnie Dodds Blvd, Mount Pleasant, SC
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Retail Space Near Ravenel Bridge
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863 SF

Retail Space Near Ravenel Bridge

Retail space in Whole Foods anchored shopping center available for lease.

855 Houston Northcutt Blvd, Mount Pleasant, SC 29464
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Mt. Pleasant Retail Space Available
$35 SF/Yr
2,975 SF

Mt. Pleasant Retail Space Available

Retail space for lease in Harris Teeter anchored shopping center.

2195 Tea Planters Ln, Mount Pleasant, SC
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Mount Pleasant Office Space Available
$28 SF/Yr
352 SF

Mount Pleasant Office Space Available

Office space in a well-maintained park with included utilities.

503 Wando Park Blvd, Mount Pleasant, SC
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Class A Flex Space
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4,380 SF

Class A Flex Space

Flex building with showroom/office and fully conditioned warehouse space.

547 Long Point Road # 104, Mount Pleasant, SC 29464
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Hotel Near Downtown Charleston
$1.00 SF/Yr
5,000 SF

Hotel Near Downtown Charleston

Hotel property for lease near downtown Charleston.

4213 Savannah Hwy, Ravenel, SC 29470
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Freestanding Office Building For Lease
$20 SF/Yr
3,400 SF

Freestanding Office Building For Lease

Two-story office property in a rapidly developing commercial corridor.

890 JOHNNIE DODDS BLVD, Mount Pleasant, SC
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Mount Pleasant Office Space Available
$26 SF/Yr
2,227 SF

Mount Pleasant Office Space Available

Office space available for lease in Mount Pleasant, SC.

1671 Belle Isle Avenue, Mount Pleasant, SC 29464
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Whipple Road Office Space Available
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Whipple Road Office Space Available

Office space for lease on Whipple Road with ample parking.

874 Whipple Rd, Mount Pleasant, SC 29464
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Charleston County, SC Commercial real estate Leasing Opportunities Market Analysis

Explore Commercial real estate leasing options in Charleston County, SC with 116 listings featured on our commercial real estate exchange. The current inventory includes 48,943,083,544 square feet of properties with an estimated lease value of $37,132.

Estimated lease rates for Commercial real estate in Charleston County, SC begin at $12 SF/Yr, with an average of $928 /Mo and extend to $36,000.
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