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    Greenwood County, SC Commercial Real Estate for Lease

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    15 properties
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    Freestanding Drive-Through Restaurant
    Updated: Aug 20
    Freestanding Drive-Through Restaurant

    219 Bypass 72 NW, Greenwood, SC 29649

    Contact for pricing
    4,300 sqft
    4,300‑square‑foot freestanding restaurant building
    Drive‑through window and on‑site parking
    Lease or ground lease availability
    Multiple full‑motion ingress and egress points
    Directly off Bypass 72 NW in Greenwood, SC
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    Recycling Center with Dock Doors
    Updated: Oct 23, 2025
    Recycling Center with Dock Doors

    105 Spray Shed Rd, Greenwood, SC 29649

    Contact for pricing
    10,000 sqft
    10,000 SF recycling center available for lease
    Fully air‑conditioned space
    Features 4 dock doors and 1 drive‑in door
    Includes a trash compactor
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    Two-Level Retail Space
    Two-Level Retail Space

    308 Main Street, Greenwood, SC 29646

    Contact for pricing

    Flexible commercial layout with customer-facing display areas, offices, kitchen facilities, and public parking on both sides.

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    Retail Shopping Center for Lease
    Retail Shopping Center for Lease

    1306-1360 Bypass 72 NE, Greenwood, SC 29649

    Contact for pricing

    Leasing opportunities are available within a multi-unit retail shopping center in Greenwood, South Carolina.

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    Restaurant Opportunity in Greenwood, SC
    Restaurant Opportunity in Greenwood, SC

    452 Bypass 72 NW, Greenwood, SC

    Contact for pricing
    7,256 sqft 2.01 AC lot

    7,256 SF restaurant space with tenant improvements on 2.11 acres.

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    Renovated Industrial Warehouse
    Renovated Industrial Warehouse

    401 Puckett Ferry Rd, Greenwood, SC 29649

    Contact for pricing
    245,835 sqft

    Renovating industrial building offers ten dock high doors, ESFR sprinklers, and up to 29' clear height.

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    Manufacturing Facility with Dock Doors
    Manufacturing Facility with Dock Doors

    401 Puckett Ferry Rd, Greenwood, SC 29649

    Contact for pricing
    232,173 sqft

    Industrial manufacturing space features 7 dock-high doors, heavy power, and clear heights up to 71 feet.

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    Restaurant Space with Patio
    Restaurant Space with Patio

    529 Bypass 72 NW, Greenwood, SC 29649

    Contact for pricing
    8,483 sqft

    Second-generation restaurant space with a patio in a retail corridor off Hwy 72 Bypass with strong foot and vehicle traffic.

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    Lakelands Industrial Park Recycling Center
    Lakelands Industrial Park Recycling Center

    103 Spray Shed Rd, Greenwood, SC 29649

    Contact for pricing
    10,000 sqft

    10,000 SF recycling center with docks and drive-in door.

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    Retail Space in Greenwood, SC
    Retail Space in Greenwood, SC

    3353 Hwy 72 221 E, Greenwood, SC 29649

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    Retail space available in a high-traffic shopping center.

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    Industrial Flex Building with Docks
    Industrial Flex Building with Docks

    1405 Bypass 72 NE, Greenwood, SC 29649

    Contact for pricing
    53,900 sqft

    Flex facility offers fully conditioned office/retail space plus warehouse areas with four dock-leveler loading docks.

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    Retail Space Anchored by Walmart
    Retail Space Anchored by Walmart

    1413 Cambridge Ave E, Greenwood, SC

    Contact for pricing
    1.03 AC lot

    Retail space available in Greenwood, South Carolina, anchored by Walmart.

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    Industrial Space For Lease
    Industrial Space For Lease

    215 Puckett Ferry Rd, Greenwood, SC 29649

    Contact for pricing

    Industrial space available for lease in Greenwood, South Carolina.

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    Commercial Land Near Walmart
    Commercial Land Near Walmart

    1421 Cambridge Ave, Greenwood, SC

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    1.58 AC lot

    Two lots available for rent near Highway 221.

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    Industrial Property for Lease
    Industrial Property for Lease

    401 Puckett Ferry Rd, Greenwood, SC 29649

    Contact for pricing

    Industrial property available for lease in Greenwood, SC.

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    Based on your search, we've compiled 113 Potential Opportunities for your consideration. Besides 15 Active listings in Greenwood County, SC, we suggest exploring alternatives. Similar 98 Properties for Sales.

    Similar Spaces for Sale in Greenwood County, SC

    Consider Similar Space for Sale. We found 98 Spaces matching your search parameters.

    Automotive Salvage Shop and Yard
    Automotive Salvage Shop and Yard

    314 S Hwy 221, Greenwood, SC 29646

    $1,599,000
    12,000 sqft 34.88 AC lot

    Operating salvage facilities include processing shops, an office, on-site housing, and a pond across a large acreage tract.

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    Metal Workshop Building and Home
    Metal Workshop Building and Home

    103 Smith St, Greenwood, SC 29649

    $750,000
    7,600 sqft

    Mixed-use property with a 50' x 100' metal workshop plus a brick home featuring dedicated office space and additional lots.

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    Multi-Unit Flex Building
    Multi-Unit Flex Building

    463 Calhoun, Greenwood, SC 29646

    $799,900
    6,000 sqft 0.47 AC lot

    GC-zoned commercial property with a resurfaced parking lot and adaptable office, retail, or light industrial configurations.

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    Auto Salvage Shop With On-Site Home
    Auto Salvage Shop With On-Site Home

    314 S Hwy 221, Greenwood, SC 29646

    $1,599,000
    12,000 sqft 34.88 AC lot

    Operating salvage-yard property with processing space, office facilities, and a two-bedroom residence.

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    Occupied Retail Space with Additional Lot
    Occupied Retail Space with Additional Lot

    1219 NE ByPass 72, Greenwood, SC 29649

    $939,000
    8,420 sqft 2.32 AC lot

    Two retail buildings totaling a substantial commercial footprint are fully occupied and include an additional lot for future development.

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    Partially Finished Live-Work Space
    Partially Finished Live-Work Space

    327 Main St floor 3, Greenwood, SC 29646

    $195,000
    1,817 sqft

    Third-floor space with C-1 zoning and flexibility for residential or commercial use.

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    Convenience Store Fuel Station
    Convenience Store Fuel Station

    623 Bypass 25 Ne, Greenwood, SC 29646

    $599,901
    1,365 sqft 0.94 AC lot

    Freestanding convenience retail building with pumps, tanks, canopy, and storage on a high-traffic US-25 corridor.

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    Flex Space with Warehouse Bays
    Flex Space with Warehouse Bays

    1201 E Cambridge Ave, Greenwood, SC 29649

    $395,000
    6,000 sqft

    Corner-lot commercial building combines finished offices, showroom space, and a fenced access area.

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    Turnkey Wedding and Event Venue
    Turnkey Wedding and Event Venue

    701 Wingert Road, Greenwood, SC 29649

    $985,000
    4,500 sqft 21.00 AC lot

    Turnkey event barn venue with bridal and groom suites, catering kitchen, manicured grounds, and ample parking.

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    Greenwood County, SC Commercial real estate Market Trends and Statistics

    Explore Commercial real estate leasing options in Greenwood County, SC with 15 listings featured on our commercial real estate exchange. The current inventory includes 571,947 square feet of properties.
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    Featured Greenwood County Real Estate Agencies

    Realmo connects you with licensed Greenwood County CRE brokers providing property specifications, local market pricing, and commercial transaction underwriting support.

    Hilton L. Dodgen Auction & Realty
    2720 Highway 25 South Greenwood, SC 29646
    Phone: 18642278777
    www.hldauction-realty.com

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